ライフサイエンスコーパス: lipidome

1 ups that collectively represent the cellular lipidome.

2 ted the phenotype to brain transcriptome and lipidome.

3 quantitative measurements across the diverse lipidome.

4 on leads to significant remodeling of the PM lipidome.

5 Pulmonary Disease (COPD) on the lung barrier lipidome.

6 netic clusters that characterized the plasma lipidome.

7 tale for free radical activity in the cell's lipidome.

8 greatest similarity to the synaptic vesicle lipidome.

9 cies have been evaluated for their meibomian lipidomes.

10 subclasses, with dramatic alterations in the lipidome across developmental stages.

11 ighly dynamic temporal response in the serum lipidome after IR exposure.

12 model genetically by solving M. tuberculosis lipidomes after deletion of the iron-dependent regulator

13 genase activity has a profound impact on the lipidome also beyond the class of ether lipids.

14 this effect by modulating the intracellular lipidome, altering fatty acid composition and restrictin

15 rformance of the PLESA approach for in-depth lipidome analysis by comparing it to conventional lipid

16 This study presents a comprehensive lipidome analysis of Sauvignon blanc grape juice by comb

17 liquid chromatography-mass spectrometry and lipidome analysis using (1)H nuclear magnetic resonance

18 itant transcriptomic measurements define the lipidome and demonstrate immediate responses in fatty ac

19 We evaluated plasma FA lipidome and its association with the prognosis of cirrh

20 to explore the influence of the grape juice lipidome and lipid metabolism in yeast on the aroma prof

21 relations of apolipoproteins with the plasma lipidome and proteome.

22 determinant of global changes in the hepatic lipidome and suggest the hypothesis that these actions c

23 l overlap in the genetic basis of the plasma lipidome and T2D-related traits.

24 that our understanding of the composition of lipidome and the function of lipids is incomplete.

25 d time-dependent responses of the macrophage lipidome and transcriptome to 25OHC treatment.

26 disease by covering a greater portion of the lipidome and using annotation which does not over-report

27 dicate an intimate coupling between cellular lipidomes and glycomes.

28 used mass spectrometry to map the proteomes, lipidomes, and metabolomes of 174 yeast strains, each la

29 male individuals suggesting a healthy plasma lipidome as resource for early biomarker discovery.

30 eding at the levels of the transcriptome and lipidome as well as metabolic fluxes, providing evidence

31 -OHOA), an antitumor compound, on xenografts lipidome based on IMS.

32 nant analysis Q(2)(Y) of 0.728] in the fecal lipidome between participants with normal blood glucose

33 ause of the great diversity exhibited in the lipidome, but no automated lipid classification exists t

34 to obtain detailed information on the whole lipidome, but the reliable quantitation of multiple lipi

35 matrices providing a deeper analysis of the lipidome by IMS.

36 We report that the lipidome changes with the cell cycle.

37 pids, we quantitatively targeted >150 plasma lipidome components in age- and body mass index-matched,

38 f concept, we employed sUHR to determine the lipidome composition and fluxes of 62 nitrogen-containin

39 Analysis of the host lipidome confirmed that symbiosis establishment was acco

40 e inter-individual variability in the plasma lipidome contributes to the genetic basis of T2D is unkn

41 ed on highly corresponding transcriptome and lipidome data.

42 Eggert et al. explore the dynamics of the lipidome during cell division and provide new insights o

43 rometry (LC-MS/MS) to investigate the murine lipidome during normal postnatal lung development.

44 The size of the putative lipidome far exceeds the number currently classified, de

45 discriminate between common and durum wheat lipidome for an authenticity purpose was explored.

46 s, for the first time, thus categorizing the lipidome for future MALDI-MSI studies of pulmonary disea

47 lipids and small molecules that constitute a lipidome for Mycobacterium tuberculosis.

48 tudy addresses temporal changes in the serum lipidome from 4 h to 28 d in nonhuman primates (NHPs) wi

49 LVPs lipidome from four patients was determined via electrosp

50 We performed a genetic study of the human lipidome in 1212 individuals from 42 extended Mexican Am

51 Here, we studied umbilical cord serum lipidome in infants who later developed T1D (N = 33); in

52 characterized the nuclear and mitochondrial lipidome in mouse liver throughout the day, upon differe

53 g of dynamic reconfiguration of the cellular lipidome in response to mild nitroxidative stress.

54 Here, we used UPLC/TOF-MS to survey the lipidome in SOD1(G86R) mice, a model of ALS.

55 We report the archaeal lipidome in SPM from diverse oceanic regimes.

56 ling of unsaturation patterns within complex lipidomes including human plasma.

57 Methods expanding coverage of the lipidome increase the likelihood of biomarker discovery

58 ociated with the model and altered the serum lipidome, independently of GLP-1 secretion.

59 implify the process and interrogate a larger lipidome into a single analysis.

60 ences reduce the dimensionality of the human lipidome into clusters that are associated with risk fac

61 l lipid species, we investigated whether the lipidome is genetically redundant and whether its geneti

62 reported, characterization of changes in the lipidome is lacking.

63 The human lipidome is made up of thousands of ubiquitous lipid spe

64 this hypothesis, we analyzed the fatty acyl lipidome of AF by liquid chromatography-mass spectrometr

65 based approach was employed to determine the lipidome of brain tissues affected by AD.

66 ferentially affected the brain and brown fat lipidome of control and P301S mice, preventing lipid vac

67 We then compared the lipidome of loa1Delta mutant and wild-type strains.

68 However, the plasma lipidome of NAFLD and whether NASH has a distinct plasma

69 pproaches have been developed to profile the lipidome of plants with increasing chemical and spatial

70 Here we quantify the comprehensive lipidome of rat synaptic membranes during postnatal deve

71 The cellular lipidome of RAW264.7 was markedly changed in a parallel

72 nol to activate lipolysis and the fatty acyl lipidome of released lipids was determined by using LC-M

73 eal the detailed composition of the membrane lipidome of the model strain Synechococcus sp. WH7803 an

74 While profiling the lipidome of the mouse brain by mass spectrometry, we dis

75 In exploring the lipidome of various living systems, novel lipids are bei

76 on the other hand, was vastly different from lipidomes of all other tested species.

77 with mass spectrometry were used to evaluate lipidomes of all tested species.

78 shotgun mass spectrometry, we determined the lipidomes of the host Madin-Darby canine kidney cell, it

79 e the high-throughput analysis of a cellular lipidome on a large scale directly from the extracts of

80 The rabbit meibomian lipidome, on the other hand, was vastly different from l

81 ss also induced a pronounced reallocation of lipidome peak area to triacylglycerols.

82 e biphasic and dynamic response to the serum lipidome post-irradiation emphasize the importance of de

83 e scope, accuracy, and dynamic range of full-lipidome quantitative shotgun profiling.

84 This suggests an essential role for lipidome remodeling in viral replication.

85 The proteome, lipidome, RNA content, and carbohydrate composition of E

86 The lipidome-scale data highlight the dynamic, light-driven

87 Therefore we concluded that the lipidome should be considered an important component of

88 Given these findings through a time-varied lipidome status, the present study provided valuable ins

89 induced some significant 1-y changes in the lipidome, they were not significantly associated with su

90 ornutum maintained more than 92% of its core lipidome under oxidative stress, patterns in biomarker d

91 Lipidomes undergo permanent extensive remodeling, but ho

92 Particularly, the lipidome varied over time, demonstrating the temporally

93 gically normal conditions, but how a healthy lipidome varies within the population is poorly understo

94 used metabolomics to test if the cord-blood lipidome was affected in children diagnosed with type 1

95 nretinide on insulin action and the cellular lipidome was assessed in a number of lipid-challenged mo

96 In this observational study, plasma FA lipidome was investigated in 51 cirrhotic patients befor

97 examine the effect of the diet on the brain lipidome, we performed Shotgun Lipidomics.

98 also find that GPMVs have slightly different lipidomes when isolated from cells adapted for growth at

99 minor lipid classes in the hepatic cellular lipidome, which collectively represent >80% of the total

100 lidated lipidomics platform to map the fecal lipidome, which integrates unique information about host

101 match to humans in terms of their meibomian lipidomes, while canines were the second closest species

102 unprecedented diversity of the thaumarchaeal lipidome with 118 different lipids suggests that membran

103 Modulating the T-cell lipidome with polyunsaturated fatty acids impaired the p

104 ted with profound alterations in the hepatic lipidome with significant reductions in both desaturatio

105 of the structure and function of lipids (the lipidome) within a living system.