ライフサイエンスコーパス: lipolysis

1 on of hormone-sensitive lipase and increased lipolysis.

2 tegration and tended to limit the intestinal lipolysis.

3 n of desnutrin/ATGL and HSL and thus adipose lipolysis.

4 d VAT and decrease in insulin suppression of lipolysis.

5 exhibits impaired lipogenesis and increased lipolysis.

6 in oxygen consumption, Ucp1 expression, and lipolysis.

7 the GTPase ARF1, which is a key activator of lipolysis.

8 ression of endogenous glucose production, or lipolysis.

9 ial targets for treating obesity, as well as lipolysis.

10 hances macrolipophagy, an initiating step in lipolysis.

11 e activity and stimulated glucose uptake and lipolysis.

12 rolase activity and isoproterenol-stimulated lipolysis.

13 olism in response to increased ATGL-mediated lipolysis.

14 size led to an increased rate and extent of lipolysis.

15 inity determines protein localization during lipolysis.

16 restored the ability of insulin to suppress lipolysis.

17 lipase (ATGL), in the regulation of cardiac lipolysis.

18 and anchors LPL to the capillary wall during lipolysis.

19 xpression does not constantly impair cardiac lipolysis.

20 fully rescued the action of insulin against lipolysis.

21 s a key role in the suppression of adipocyte lipolysis.

22 sulin versus niacin-medicated suppression of lipolysis.

23 substrate utilization by regulating cardiac lipolysis.

24 PDE3B were examined for their regulation of lipolysis.

25 I, contributing to VLDL/HDL distribution and lipolysis.

26 t required for insulin to suppress adipocyte lipolysis.

27 d the loss of insulin-mediated inhibition of lipolysis.

28 the surface of lipid droplets and suppressed lipolysis.

29 g a critical role for PKA in Plin5-regulated lipolysis.

30 it inhibits basal and facilitates stimulated lipolysis.

31 le of perilipins 2 and 3 in regulating basal lipolysis.

32 he severe metabolic consequences of impaired lipolysis.

33 diated inhibition of glucose uptake requires lipolysis.

34 and forced expression of miR-145 attenuates lipolysis.

35 n adipocytes, plays a key role in regulating lipolysis.

36 they exhibited altered glucose disposal and lipolysis.

37 lipase (ATGL), a key enzyme in intracellular lipolysis.

38 d in de novo lipogenesis, beta-oxidation, or lipolysis.

39 before digestion but did not affect gastric lipolysis.

40 en transiently adapt to increased peripheral lipolysis.

41 ed hGP but failed to suppress adipose tissue lipolysis.

42 ase (ATGL), the key enzyme for intracellular lipolysis.

43 ed SNS signalling and possibly cause reduced lipolysis.

44 e stimulated both glucose uptake (17.4%) and lipolysis (17.7%); the mRNA expression of glucose transp

45 all adipose cells; increase in VAT, IHL, and lipolysis; 45% worsening of IMGU; and decreased expressi

46 issue inflammation and insulin regulation of lipolysis.A double-blind, placebo-controlled study compa

47 amus (MBH), display impaired fasting-induced lipolysis accompanied by a decreased norepinephrine cont

48 that fatty acids derived from ATGL-catalyzed lipolysis act as PPAR-alpha ligands.

49 Moreover, FAs from higher lipolysis activate peroxisome proliferator-activated rec

50 , our data indicate that excessive adipocyte lipolysis activates the JNK/NFkappaB pathway leading to

51 We found that lipolysis activates the JNK/NFkappaB signaling pathway a

52 We now show that defective lipolysis activates the Swe1 morphogenesis checkpoint ki

53 The structural determinants of ABHD5 lipolysis activation, however, are unknown.

54 years ago, to identify determinants of ABHD5 lipolysis activation.

55 ts in dysfunctional elevated lipogenesis and lipolysis activities in mouse WAT as well as in stromal

56 Macrophage-induced WAT lipolysis also stimulates hepatic gluconeogenesis, promo

57 duces FGF21, which suppresses adipose tissue lipolysis, ameliorating hepatic steatosis.

58 urs) induction of gene networks that promote lipolysis and adipogenesis in mammalian adipocytes.

59 expression of genes related to proteolysis, lipolysis and amino acid/lipid catabolism and significan

60 anistic insights into the cross talk between lipolysis and autophagy, two key metabolic responses to

61 by shutting down catabolic processes such as lipolysis and beta-oxidation.

62 , a direct relationship was observed between lipolysis and carotenoid micellarisation for all emulsio

63 levels positively correlated with markers of lipolysis and cellular senescence.

64 ciency results in a de-repression of cardiac lipolysis and decreased cardiac TAG content.

65 valuable information about the extent of the lipolysis and enables a rapid discrimination among sampl

66 te impact of Plin5 overexpression on cardiac lipolysis and energy metabolism.

67 pocyte-specific gp130 deletion reduced basal lipolysis and enhanced insulin's ability to suppress lip

68 ltransferase-2 (DGAT2), and (b) decreases in lipolysis and FA beta-oxidation that paralleled a prolon

69 However, the role of AMPK in lipolysis and FA metabolism in adipose tissue has been c

70 c AMP (cAMP)/protein kinase A (PKA)-mediated lipolysis and fatty acid and glucose oxidation, as well

71 al framework for understanding intravascular lipolysis and GPIHBP1 and LPL mutations causing familial

72 xpression of FGF21 suppressed adipose tissue lipolysis and improved hepatic steatosis in these mice.

73 ther metformin has any additional effects on lipolysis and inflammation that will enhance burn recove

74 ction of a beta3-adrenergic agonist, in vivo lipolysis and ketogenesis were decreased in G0S2 transge

75 cytokines and stress hormones that stimulate lipolysis and ketogenesis.

76 unted beta-adrenoreceptor (beta-AR)-mediated lipolysis and lipid oxidation in adipose tissue, but the

77 uding impaired insulin action in suppressing lipolysis and lipid oxidation, accompanied by beta-cell

78 fat diets, associated with decreases in both lipolysis and lipid synthesis.

79 tence of an adaptive interdependence between lipolysis and lipid synthesis.

80 or of plasma TG levels through regulation of lipolysis and lipid synthesis.

81 ermogenic gene expression, and downregulated lipolysis and lipogenesis genes in epididymal WAT.

82 serving to facilitate the tight coupling of lipolysis and lipogenesis in activated brown fat.

83 ight, but correlated with down-regulation of lipolysis and lipogenic indices.

84 issue insulin action results in unrestrained lipolysis and lipotoxicity, which are hallmarks of the m

85 possibly secondary to the effects of reduced lipolysis and lower circulating fatty acid binding prote

86 he decreased LD formation is due to enhanced lipolysis and not caused by reduced triglyceride synthes

87 se cell size, VAT, or insulin suppression of lipolysis and only 8% worsening of insulin-mediated gluc

88 ence of ovalbumin and soy protein isolate on lipolysis and oxidation taking place during in vitro gas

89 leurotus sajor-caju mushroom on lipogenesis, lipolysis and oxidative stress in 3T3-L1 cells were inve

90 ling in POMC neurons controls adipose tissue lipolysis and prevents high-fat diet-induced hepatic ste

91 used by PHD2 inhibition in adipocytes blunts lipolysis and promotes benign adipose tissue expansion a

92 In particular, Egr1 suppresses lipolysis and promotes fat accumulation in adipocytes by

93 Lipolysis and proteolysis levels in cheeses from UHPH-tr

94 I, a critical inhibitor of triglyceride (TG) lipolysis and remnant TRL clearance.

95 ncy reduces the basal rate of adipose tissue lipolysis and results in adipocyte hypertrophy upon agin

96 These data demonstrate a critical role for lipolysis and substrate delivery to the liver, secondary

97 were treated with isoproterenol to activate lipolysis and the fatty acyl lipidome of released lipids

98 Br2 mediates ER stress-induced inhibition of lipolysis and thermogenesis in BAT.

99 ns adrenergic signaling, thereby attenuating lipolysis and thermogenic respiration.

100 beta3-adrenergic receptors (ADRB3) triggers lipolysis and up-regulates production of IL-6 in adipocy

101 le in the regulation of ACTH-induced adipose lipolysis and whole-body energy balance.

102 ater circulating TG disposal, lower systemic lipolysis, and better fatty acid handling by lean tissue

103 increased basal and isoproterenol-stimulated lipolysis, and decreased adipocyte differentiation, whil

104 ory cytokines and stress hormones, increased lipolysis, and decreased G0S2 and increased CGI-58 mRNA

105 Insulin is a key regulator of adipose tissue lipolysis, and impaired adipose tissue insulin action re

106 promote hepatic lipogenesis, adipose tissue lipolysis, and impaired beta-oxidation), these factors c

107 us adipose cell size, insulin suppression of lipolysis, and regional fat responses to short-term over

108 y enhancing VLDL-TG uptake, intracellular TG lipolysis, and subsequent mitochondrial fatty acid oxida

109 ulators involved in fatty acid oxidation and lipolysis, and thus promoted hepatic steatosis.

110 file, mitochondrial capacity, fat oxidation, lipolysis, and tissue-specific insulin sensitivity.

111 unction, absent browning of WAT, and reduced lipolysis, and were therefore cold-intolerant.

112 and tested which intracellular mediators of lipolysis are affected in adipose tissue.

113 ins that regulate energy homeostasis through lipolysis are thus likely to play an important role in d

114 expression but still fails to inhibit basal lipolysis as effectively as wild-type perilipin 1.

115 increasing expression of CPT1A, and inducing lipolysis as indicated by elevation of the lipase ATGL,

116 n of hormone-sensitive lipase and consequent lipolysis, as do knockouts of dopamine beta-hydroxylase,

117 We investigated whole-body lipolysis, ATIS, and beta-cell function relative to ATIS

118 the development of LVH, adipose tissue (AT) lipolysis becomes elevated upon endurance training to co

119 hawing and pasteurization increased the milk lipolysis before digestion but did not affect gastric li

120 With higher overall adipose lipolysis, both models of AMPK-ASKO mice are lean, havin

121 eficiency is associated with increased basal lipolysis, 'browning' of white fat and a healthy metabol

122 rom P. sajor-caju stimulated lipogenesis and lipolysis but attenuated protein carbonyl and lipid hydr

123 d this medium stimulated UCP1 expression and lipolysis by 3T3-L1 adipocytes.

124 Mechanistically, we show that intravascular lipolysis by adipocyte lipoprotein lipase and hepatic up

125 inflammasome-activated macrophages improved lipolysis by decreasing levels of MAOA and caspase-1.

126 ific overexpression of G0S2 inhibits cardiac lipolysis by direct protein-protein interaction with ATG

127 RP3 in ageing restored catecholamine-induced lipolysis by downregulating growth differentiation facto

128 mice, supporting the model that core reduces lipolysis by engaging ATGL.

129 Inhibition of adipocyte lipolysis by insulin is important for whole-body energy

130 pocytes, regulates both basal and stimulated lipolysis by interacting with adipose triglyceride lipas

131 scavenger receptor CD36 and their subsequent lipolysis by lysosomal acid lipase (LAL) was important f

132 lipolysis is tightly regulated and excessive lipolysis causes hepatic steatosis, as NEFA released fro

133 gy demands under stress, whereas superfluous lipolysis causes metabolic disorders, including dyslipid

134 basal and induced glucose uptake as well as lipolysis compared with untreated controls.

135 Chronically enhancing WAT lipolysis could produce ectopic steatosis because of an

136 A lipolysis degree similar to that reported in vivo was re

137 eleased from succinate-induced inhibition of lipolysis, demonstrating a function of Sucnr1 in adipose

138 The kinetics of proteolysis and lipolysis differed according to the physiological stage

139 ovide the first evidence that adipose tissue lipolysis directly promotes the development of exercise-

140 accumulation of sn-1,3 DAG originating from lipolysis does not inhibit insulin-stimulated glucose up

141 ed by impaired suppression of adipose tissue lipolysis due to decreased insulin secretion and to a re

142 hypertriglyceridemia and excessive systemic lipolysis during intravenous lipid overload.

143 This results in enhanced lipolysis, elevated concentrations of free fatty acids,

144 y of IKKbeta also leads to increased adipose lipolysis, elevated plasma free fatty acid (FFA) levels,

145 tty acid metabolism (lipogenesis, oxidation, lipolysis, esterification) and fatty acid uptake in >900

146 que provides a complete molecular picture of lipolysis, evidencing for the first time, whether prefer

147 Tween80 emulsions led to a higher lipolysis extent (53-57%) and carotenoid bioaccessibilit

148 ameliorates ER stress-induced inhibition on lipolysis, fatty acid oxidation, oxidative metabolism, a

149 s and enhanced insulin's ability to suppress lipolysis from mesenteric but not epididymal adipocytes.

150 eported patients with T2D, we also estimated lipolysis (from [(2)H5]glycerol turnover rate and circul

151 GAT lipolysis fuels fatty acid oxidation in LSCs, especially

152 However, the specific roles of lipolysis-generated mediators in adipose inflammation re

153 Excessive adipocyte lipolysis generates lipid mediators and triggers inflamm

154 In agreement with reduced WAT lipolysis, glucocorticoid- initiated hepatic steatosis a

155 Whole-body lipolysis (glycerol appearance rate [GlyRa], [(2)H5]glyc

156 Endogenous glucose production, lipolysis (glycerol, nonesterified fatty acid), and glyc

157 Lipolysis (glycerol, nonesterified fatty acids) and endo

158 liver fat induces mitochondrial metabolism, lipolysis, glyceroneogenesis and a switch from lactate t

159 abetes (T1D) and measure rates of whole-body lipolysis, hepatic acetyl CoA content, pyruvate carboxyl

160 Leptin infusion reduced rates of lipolysis, hepatic glucose production (HGP), and hepatic

161 Leptin-induced decreases in lipolysis, HGP, and ketogenesis in DKA were also nullifi

162 etic (T1D) rats exhibited decreased rates of lipolysis, HGP, and ketogenesis; these effects were reve

163 l size, VAT, IHL, and insulin suppression of lipolysis highlight these factors as potential mediators

164 Pancreatic lipase expression increased lipolysis in 3T3-L1 cells.

165 was found that cranberries directly induced lipolysis in adipocytes and down-regulated the expressio

166 These findings suggest that unsuppressed lipolysis in adipocytes elicited by HFD feeding is linke

167 Previously, we have found that lipolysis in adipocytes is controlled by early growth re

168 hereas perilipin 1 potently suppresses basal lipolysis in adipocytes, perilipins 2 and 3 facilitate h

169 ORLA promotes insulin-induced suppression of lipolysis in adipocytes.

170 rol (TAG) hydrolase activity, lowering basal lipolysis in adipose tissue.

171 RF4), a transcriptional regulator of fasting lipolysis in adipose tissue.

172 We aimed to measure the rate and extent of lipolysis in an in vitro duodenum digestion model, using

173 moxia and reduced beta-adrenergic-stimulated lipolysis in both normoxia and hypoxia.

174 P/PKA pathways, contributing to the enhanced lipolysis in Cav-1 KO cells.

175 gene expression at multiple levels, enhances lipolysis in epididymal WAT (eWAT) because of the upregu

176 ibit a pro-inflammatory phenotype and induce lipolysis in GAT.

177 ulate the age-related reduction in adipocyte lipolysis in mice by lowering the bioavailability of nor

178 Defective lipolysis in mice lacking adipose triglyceride lipase pr

179 ed FLD of Angptl4 is sufficient to stimulate lipolysis in mouse primary adipocytes and that increasin

180 A selective PHD inhibitor suppressed lipolysis in murine and human adipocytes in vitro and in

181 an unanticipated role of Cav-1 in regulating lipolysis in non-adipose tissue, indicating that Cav-1 i

182 ne-depleted adipocytes exhibited lower basal lipolysis in normoxia and reduced beta-adrenergic-stimul

183 ins 2 and 3 facilitate higher rates of basal lipolysis in other tissues where constitutive traffic of

184 n, energy expenditure and PYY, and decreased lipolysis in overweight/obese men.

185 m in EC and that it regulates cAMP-dependent lipolysis in part via the autocrine production of PGI2.

186 inhibit beta-adrenoreceptor agonist-promoted lipolysis in primary mouse adipocytes and to promote che

187 like adipocytes, also undergo cAMP-mediated lipolysis in response to beta-AR stimulation.

188 n impact of FA synthesis and mobilization by lipolysis in somatic tissues on oocyte fate in Caenorhab

189 creased AMPK and HSL activities and promoted lipolysis in T37i differentiated brown adipocytes.

190 overexpression (Ad-FLD) not only induces WAT lipolysis in vivo but also reduces diet-induced obesity

191 he role of AMPK in the regulation of adipose lipolysis in vivo, we generated mice with adipose-tissue

192 ions in hepatic acetyl CoA by suppression of lipolysis in white adipose tissue (WAT) leading to reduc

193 Glucocorticoids promote lipolysis in white adipose tissue (WAT) to adapt to ener

194 ecessary and sufficient for the induction of lipolysis in white adipose tissue and are an efferent ef

195 Lipolysis in white adipose tissues (WAT) and lipolysis-i

196 Lipolysis in white adipose tissues (WAT) and lipolysis-induced blood glucose rise were increased in I

197 Mechanistically, we found that adipose lipolysis-induced SphK1 up-regulation is mediated by the

198 red insulin-mediated Akt phosphorylation and lipolysis inhibition.

199 In adipocytes, lipolysis is a highly regulated process involving hormon

200 leagues provide evidence that suppression of lipolysis is a key facet of leptin-mediated restoration

201 in lymphocytes and show that cell intrinsic lipolysis is deterministic for memory T cell fate.

202 in adipocytes is normal in the elderly, how lipolysis is impaired in ageing remains unknown.

203 Adipose tissue lipolysis is tightly regulated and excessive lipolysis c

204 domain responsible for stimulating adipocyte lipolysis is unknown.

205 zyme that mediates the rate-limiting step in lipolysis, is a key point of this regulation.

206 (FA) of o/w emulsions on both the pancreatic lipolysis kinetics and the bioaccessibility of released

207 tric phase were directly associated with the lipolysis kinetics during the intestinal phase.

208 ets was the key parameter to control gastric lipolysis kinetics, the pattern of released fatty acids

209 ng gastrointestinal conditions in modulating lipolysis kinetics.

210 intralipids or by inhibiting adipose tissue lipolysis led to failure in EGP suppression, thus suppor

211 erent in vitro digestion experiments and the lipolysis levels reached were evaluated using (1)H NMR s

212 tion raised EGP, lowered TGD, and stimulated lipolysis, LOx, and ketogenesis.

213 s TG-lowering alleles involved in peripheral lipolysis (LPL and ANGPTL4) had no effect on liver fat b

214 dicated by elevation of the lipase ATGL, the lipolysis marker glycerol and release of fatty acids.

215 The results show that IL-6 cytokine-induced lipolysis may be restricted to mesenteric white adipose

216 Lipolysis measurements revealed that Sucnr1(-/-) mice we

217 lly, we found that hypothalamic induction of lipolysis mediated the brain's action in promoting this

218 The kinetics of lipolysis, micelle formation and carotenoid bioaccessibi

219 ns 2 or 3 stabilize ABHD5 and suppress basal lipolysis more effectively than WT perilipins 2 or 3.

220 hat, in addition to its ability to stimulate lipolysis, NE induces energy expenditure in BA by promot

221 Increased lipolysis, nutrient transfer to the milk gland, and milk

222 Lipolysis occurred in milk before digestion and was high

223 Notably, PKA-induced lipolysis of LDs enriched with Plin5 carrying a single m

224 iggers ER autophagy and subsequent lysosomal lipolysis of TG, followed by mitochondrial oxidation of

225 ein lipase (LPL) activity and stimulates the lipolysis of triacylglycerol stored by adipocytes in the

226 We conclude that UFAs generated via lipolysis of visceral fat by pancreatic lipases convert

227 transformed" extract could be used to induce lipolysis on fat tissue.

228 we investigated the impact of adipose tissue lipolysis on the development of exercise-induced cardiac

229 had no beneficial effects on adipose tissue lipolysis or inflammation in insulin-resistant adults.

230 y, catecholamine-induced lipid mobilization (lipolysis), or insulin-stimulated lipid synthesis in adi

231 ected carotenoid bioaccessibility (p<0.001), lipolysis, particle size and zeta potential.

232 Additionally, lipolysis, particle size, and zeta potential of the mice

233 To test whether this beta-AR-dependent lipolysis pathway was altered in a model of alcoholic fa

234 m cells through necrosis, by attenuating the lipolysis pathway, but spared differentiated cells.

235 report that during catecholamine-stimulated lipolysis, Perilipin 5 is phosphorylated by protein kina

236 n recent work suggesting that pancreatic fat lipolysis plays an important role in SAP, we evaluated t

237 Adipose tissue lipolysis produces glycerol and nonesterified fatty acid

238 Results also suggest that lipolysis products are very rapidly solubilized in the b

239 evidence that gp130-mediated adipose tissue lipolysis promotes hepatic steatosis and insulin resista

240 man milk on its gastrointestinal kinetics of lipolysis, proteolysis and structural disintegration.

241 Together, we show that autophagy-mediated lipolysis provides free fatty acids to support a mitocho

242 eoxy-D-glucose/positron emission tomography, lipolysis (RaGly) with [U-(2) H5 ]-glycerol, oral glucos

243 The estimated lipolysis rate constants of the studied FA (C8:0, C10:0>

244 he I148M variant impedes intrahepatocellular lipolysis rather than stimulates TAG synthesis.

245 ificant increase in UCP1 mRNA (p = 0.03) and lipolysis-related ATGL mRNA (p = 0.04).

246 Lipidomic analyses indicate that TAG lipolysis releases free fatty acids at a time that corre

247 revent lipotoxicity, whereas TAG hydrolysis (lipolysis) remobilizes fatty acids from endogenous stora

248 Glucocorticoid-induced lipolysis requires the phosphorylation of cytosolic horm

249 adipocytes reduced or increased ACTH-induced lipolysis, respectively.

250 droxybutyrate concentrations and the rate of lipolysis rose markedly.

251 is (PRIM) or secondarily from adipose tissue lipolysis (SEC).

252 Lipolysis showed an early decrease in glycerol release i

253 rves for energy, in such a way that blocking lipolysis starves them to death.

254 ition of the JNK/NFkappaB axis abrogated the lipolysis-stimulated COX-2 expression.

255 The lipolysis-stimulated lipoprotein receptor (LSR) is the h

256 Here, we show that Lipolysis-stimulated lipoprotein receptor (LSR), a compo

257 appears to cause exacerbated adipose tissue lipolysis, suggesting that strategies to reduce muscle l

258 Inhibition of lipolysis suppressed M2 activation during infection with

259 We also show that lipolysis suppresses glucose uptake by inhibiting the ma

260 2-deficient hepatocytes exhibit increased TG lipolysis, TG turnover, and fatty acid oxidation as comp

261 However, Ad-PLIN5 cells had higher lipolysis than Ad-PLIN2 cells, which increased further b

262 adipose triglyceride lipase (ATGL)-mediated lipolysis that plays important roles in metabolism, tumo

263 Catecholamine-induced lipolysis, the first step in the generation of energy su

264 gh ACTH was known to stimulate PKA-dependent lipolysis, the functional involvement of MRAP in adipocy

265 The extent of lipolysis, the molar proportions of acyl groups/fatty ac

266 nd considers CLA's linkage with lipogenesis, lipolysis, thermogenesis, and browning of white and brow

267 ode that links beta-adrenergic signaling and lipolysis to changes in the transcriptional regulation o

268 a highly regulated metabolic process called lipolysis to free fatty acids that serve as energy subst

269 enhance the ability of Atgl/Cgi-58-mediated lipolysis to induce the activity of peroxisome prolifera

270 tochondrial biogenesis, lipid oxidation, and lipolysis under a high fat diet, leading to elevated ene

271 ered lipid metabolism, in particular induced lipolysis upon starvation.

272 issue compared with niacin, which suppresses lipolysis via a different pathway.

273 Basal and adrenergically stimulated lipolysis was attenuated in adipose explants isolated fr

274 Conversely, lipolysis was decreased and lipogenesis was increased in

275 Robustly enhanced lipolysis was found in gonadal fat of Adipoq(-/-) dams.

276 Suppression of lipolysis was greater during PeHI than PoHI and was dela

277 Lipolysis was higher in males than females in C and HG c

278 and Glut4 translocation were decreased, and lipolysis was increased.

279 uppress hepatic acetyl CoA, PC activity, and lipolysis was lost in high-fat-fed rats, a phenomenon re

280 The rate of lipolysis was monitored by measuring the increase of abs

281 Despite inactivating BSSL, instantaneous lipolysis was not affected by pasteurization (mean +/- S

282 Lipolysis was not stimulated by HG or high hydrocortison

283 In general, results indicated that enzymatic lipolysis was the driving factor influencing the quality

284 uced, but the ability of insulin to suppress lipolysis was unaltered.

285 atriuretic peptide, and thus, induce adipose lipolysis, we studied peripheral and systemic metabolism

286 f insulin such as protein synthesis and anti-lipolysis were normal.

287 ile concentration, on the extent of in vitro lipolysis when using a static model that simulates human

288 ic steatosis due to increased adipose tissue lipolysis, when fasted or fed a high-fat low-carbohydrat

289 During lipolysis, when LDs and their surfaces shrink, some, but

290 s and profound suppression of adipose tissue lipolysis, which decreases delivery of FAs to the liver.

291 hite adipose tissue (WAT) leads to increased lipolysis, which further increases hepatic triglyceride

292 n, hepatic acetyl CoA content and whole-body lipolysis, which results from decreases in plasma ACTH a

293 Consequently, nicotine increases lipolysis, which results in body weight reduction, but t

294 e-sensitive lipase and consequently activate lipolysis, which then enables the transfer of fatty acid

295 storage and diminish macrophage-induced WAT lipolysis will reverse the root causes of type 2 diabete

296 oncentration in adipose tissue, and restored lipolysis with increased levels of the key lipolytic enz

297 However, the mechanisms that link lipolysis with inflammation remain elusive.

298 tion of the PKA pathway and of lipid droplet lipolysis with transcriptional regulation to promote eff

299 duced inflammation that stimulates increased lipolysis within adipocytes.

300 R299N and ABHD5 G328S) selectively disrupted lipolysis without affecting ATGL lipid droplet transloca