ライフサイエンスコーパス: lipooligosaccharide

1 efficiently than those induced by wild-type lipooligosaccharide.

2 onserved component of lipopolysaccharide and lipooligosaccharide.

3 and synthesized a distinct, faster-migrating lipooligosaccharide.

4 ialic acid to a membrane acceptor resembling lipooligosaccharide.

5 iron-regulated proteins TbpB and CopB and to lipooligosaccharide.

6 serum samples contained new IgG directed at lipooligosaccharide.

7 was not reproduced by purified H. influenzae lipooligosaccharide.

8 reas the other aggregates contained only 14C-lipooligosaccharide.

9 ivation and attachment of sialic acid to the lipooligosaccharide.

10 defined but is not related to sialylation of lipooligosaccharide.

11 nfluenzae contributes to the toxicity of the lipooligosaccharide.

12 ntibody response directed against gonococcal lipooligosaccharide.

13 activation correlated with disaggregation of lipooligosaccharides.

14 , due to oligosaccharide moieties within the lipooligosaccharides.

15 Isolated N. gonorrhoeae lipooligosaccharide, a known virulence factor from this

16 The lipooligosaccharides, a major component of the outer mem

17 mnus, formalin-fixed H. somnus, nor purified lipooligosaccharide altered monolayer integrity within a

18 ATCC 43431 genes encode proteins involved in lipooligosaccharide and capsular biosynthesis, as expect

19 ho-N-acetylneuraminic acid, which sialylates lipooligosaccharide and converts to serum resistance gon

20 o major surface features, the outer membrane lipooligosaccharide and flagella, are highly variable an

21 rophoresis mobilities that resemble those of lipooligosaccharide and lipopolysaccharide.

22 lotting and mass spectrometry indicated that lipooligosaccharide and outer membrane proteins P2 and P

23 ng STAT to MSn data generated from bacterial lipooligosaccharides and an N-linked glycan.

24 sion by human epithelial cells than did NTHI lipooligosaccharides and envelope proteins.

25 ipids change systematically from hydrophilic lipooligosaccharides and phenolic glycolipids to hydroph

26 ng the mutant in expression of Opa proteins, lipooligosaccharide, and pilin.

27 attach to peptides, proteins, carbohydrates, lipooligosaccharides, and DNA.

28 OMPs, fimbriae, pili, and lipooligosaccharide are several types of surface antigen

29 d (sialic acid) can be incorporated into the lipooligosaccharides as a terminal nonreducing sugar.

30 Thus, in addition to lipooligosaccharide assembly, Kdo is required for mening

31 An anti-lipooligosaccharide bactericidal monoclonal Ab (mAb) 2C7

32 bstitutions from the heptose II group of the lipooligosaccharide beta-chain did not impact levels of

33 sertional inactivation of the phase-variable lipooligosaccharide biosynthesis gene lgtC in R2866 augm

34 ied a PCR fragment with high homology to the lipooligosaccharide biosynthesis gene lic2B (originally

35 pervariable regions, such as the capsule and lipooligosaccharide biosynthesis regions.

36 unique genes in H. somnus 129Pt involved in lipooligosaccharide biosynthesis, carbohydrate uptake an

37 enes encode proteins involved in capsule and lipooligosaccharide biosynthesis, restriction and modifi

38 rain 2019 genes involved in carbohydrate and lipooligosaccharide biosynthesis.

39 phosphoglucomutase, an enzyme important for lipooligosaccharide biosynthesis.

40 coccal PorB.1B in the presence of sialylated lipooligosaccharide bound more fH, more effectively limi

41 Exogenous sialylation of gonococcal lipooligosaccharide causes resistance to serum bacterici

42 ids, reminiscent of the trehalose-containing lipooligosaccharide class of antigens but lacking the no

43 Lipooligosaccharide configurations were predicted in non

44 dium containing [(14)C]acetate yielded (14)C-lipooligosaccharides containing approximately 600 cpm/ng

45 iants within biofilms have on their surfaces lipooligosaccharides containing sialic acid (NeuAc) and

46 Gel sieving resolved 14C-lipooligosaccharide-containing aggregates with an estima

47 adds the terminal N-acetylglucosamine to the lipooligosaccharide core of Y. pestis.

48 of intranasal immunization with a detoxified-lipooligosaccharide-cross-reactive mutant of diphtheria

49 An M. kansasii, DeltaMKAN27435 partially lipooligosaccharide-deficient mutant absorbed marginally

50 Detoxified-lipooligosaccharide (dLOS)-protein conjugates from nonty

51 oraxella catarrhalis strain 25238 detoxified lipooligosaccharide (dLOS)-protein conjugates induced a

52 e substitution from the lipid A component of lipooligosaccharide, due to insertional inactivation of

53 molecular determinants of host-meningococcal lipooligosaccharide (endotoxin) interactions at patho-ph

54 bacterial DNA, outer membrane proteins, and lipooligosaccharide (endotoxin).

55 e, but not TLR4 agonists including LPS or GC lipooligosaccharide enhanced HIV-1 infection of primary

56 lecules (PorB.1A or PorB.1B); sialylation of lipooligosaccharide enhances fH binding.

57 ed bactericidal Abs directed against the 2C7 lipooligosaccharide epitope as well as murine antigonoco

58 A gonococcal lipooligosaccharide epitope defined by the mAb 2C7 is be

59 l antibody (MAb) 2C7 recognized a gonococcal lipooligosaccharide epitope, identified the epitope dire

60 not affect either the rate of growth or the lipooligosaccharide expression profile of this mutant.

61 The lipooligosaccharide from Neisseria gonorrhoeae (GC), con

62 unresponsive to protein-free preparations of lipooligosaccharide from Neisseria gonorrhoeae and LPS f

63 nsis LPS did not compete with a radiolabeled lipooligosaccharide from Neisseria meningitidis for bind

64 and composition analyses have shown that the lipooligosaccharides from three other H. ducreyi strains

65 The structures of the lipooligosaccharides fromBrucella melitensismutants affe

66 involve outer surface structures, including lipooligosaccharide glycans and outer surface proteins.

67 This strain produced the lipooligosaccharide glycoforms produced by the parental

68 We report the cloning of the gene (lgtG, lipooligosaccharide glycosyl transferase G) encoding the

69 resent study, the Neisseria gonorrhoeae lgtA lipooligosaccharide glycosyltransferase gene was used to

70 Nontypeable Haemophilus influenzae (NTHI) lipooligosaccharide htrB mutants exhibited greater than

71 sule expression decreased binding of an anti-lipooligosaccharide IgM mAb ( approximately 1.2- to 2-fo

72 were incubated with H. ducreyi or H. ducreyi lipooligosaccharide in vitro.

73 14C-Labeled capsule copurified with (14)C-lipooligosaccharides in peak B from NMBACE1, whereas the

74 Lipooligosaccharides in peaks A and B had the same fatty

75 emonstrate that the physical presentation of lipooligosaccharide, including possible interactions wit

76 acid and that the sialic acid content of the lipooligosaccharides increases concomitant with the tran

77 esults in the loss of phosphorylation of the lipooligosaccharide inner core and causes attenuation in

78 em results in loss of phosphorylation of the lipooligosaccharide inner core and causes attenuation in

79 derived sialic acid to Neisseria gonorrhoeae lipooligosaccharide is hypothesized to be an important m

80 suggesting that neither pili nor full-length lipooligosaccharide is required for H. ducreyi to bind t

81 hat, like the alpha chain, the beta chain of lipooligosaccharide is subject to antigenic variation.

82 he pathway of sialic acid incorporation into lipooligosaccharides is understood, the transporter resp

83 Structural studies demonstrated that the lipooligosaccharide isolated from the mutant strain lack

84 -time of flight mass spectometry analysis of lipooligosaccharides isolated from a biofilm, the plankt

85 onosaccharides (5-8), which are fragments of lipooligosaccharide IV (LOS-IV) from Mycobacterium marin

86 A mutant that produces truncated lipooligosaccharide (KDO(2)-lipid A) and a mutant defect

87 serves a dual role in modifying not only the lipooligosaccharide lipid anchor lipid A with pEtN, but

88 se membrane fibrils and blebs, which contain lipooligosaccharide (LOS) and immunoglobulin binding pro

89 . gonorrhoeae FA19 that produces a truncated lipooligosaccharide (LOS) and is non-transformable.

90 innate immune signaling pathways, including lipooligosaccharide (LOS) and other pathogen-derived mol

91 Outer membrane complex containing both lipooligosaccharide (LOS) and proteins and LOS from Neis

92 ilms differentially express both epitopes of lipooligosaccharide (LOS) and the outer membrane protein

93 Human IgGs that bind the neisserial L7 lipooligosaccharide (LOS) are bactericidal for L3,7 and

94 Outer membrane proteins (OMP) and lipooligosaccharide (LOS) are major surface antigens of

95 We identified Neisseria meningitidis lipooligosaccharide (LOS) as an acceptor for complement

96 is selection was observed in three different lipooligosaccharide (LOS) backgrounds, indicating that i

97 Lipooligosaccharide (LOS) based conjugate vaccines deriv

98 ylobacter CPS independent of the pathway for lipooligosaccharide (LOS) biosynthesis and identify a no

99 cant variation in the genetic content of the lipooligosaccharide (LOS) biosynthesis loci with concomi

100 The lipooligosaccharide (LOS) biosynthesis region is one of

101 d the role of cj1136 in C. jejuni virulence, lipooligosaccharide (LOS) biosynthesis, and host coloniz

102 Analysis of tetrameric repeat regions within lipooligosaccharide (LOS) biosynthetic genes in both str

103 terminal N-acetyllactosamine present on its lipooligosaccharide (LOS) by acquiring CMP-N-acetyl-5-ne

104 ransferase (Lst) that sialylates the surface lipooligosaccharide (LOS) by using exogenous (in all N.

105 nt study, we show that Neisseria gonorrhoeae lipooligosaccharide (LOS) can bind to the asialoglycopro

106 f Neisseria gonorrhoeae may express a single lipooligosaccharide (LOS) component on their cell surfac

107 uctural and antigenic phase variation in its lipooligosaccharide (LOS) components after in vivo and i

108 emophilus ducreyi strains examined contain a lipooligosaccharide (LOS) consisting of a single but var

109 lly transmitted disease chancroid produces a lipooligosaccharide (LOS) containing a terminal sialyl N

110 Purified lipooligosaccharide (LOS) containing lipid A devoid of t

111 The inner core of neisserial lipooligosaccharide (LOS) contains heptose residues that

112 Neisserial lipooligosaccharide (LOS) contains three oligosaccharide

113 of Campylobacter jejuni 81-176 lgtF and galT lipooligosaccharide (LOS) core mutants.

114 Three genes involved in biosynthesis of the lipooligosaccharide (LOS) core of Campylobacter jejuni M

115 a inhabiting mucosal surfaces, NTHi produces lipooligosaccharide (LOS) endotoxins that lack the O sid

116 NTHI produces lipooligosaccharide (LOS) endotoxins which lack polymeri

117 erparts in E. coli; (iii) sialylation of the lipooligosaccharide (LOS) epitope recognized by monoclon

118 A candidate vaccine that targets a lipooligosaccharide (LOS) epitope recognized mAb 2C7 att

119 gnizes a widely in vivo-expressed gonococcal lipooligosaccharide (LOS) epitope.

120 asymmetry, with lipopolysaccharide (LPS) or lipooligosaccharide (LOS) exclusively in the outer leafl

121 The lipooligosaccharide (LOS) expressed by gonococci spontan

122 ophilus ducreyi 35000 possessing a truncated lipooligosaccharide (LOS) failed to bind the LOS-specifi

123 lity, we found that the toxicity of purified lipooligosaccharide (LOS) from M986, a group B disease s

124 Lipooligosaccharide (LOS) from Moraxella catarrhalis has

125 We have previously shown that the lipooligosaccharide (LOS) from Neisseria meningitidis an

126 Lipooligosaccharide (LOS) from Neisseria meningitidis en

127 decyl sulfate-polyacrylamide gel analysis of lipooligosaccharide (LOS) from Neisseria meningitidis ha

128 The native lipooligosaccharide (LOS) from Neisseria meningitidis st

129 Lipooligosaccharide (LOS) glycoforms from Haemophilus in

130 Lipooligosaccharide (LOS) has been implicated in the adh

131 Lipooligosaccharide (LOS) has been shown to play a role

132 e alpha-oligosaccharide (alpha-OS) moiety of lipooligosaccharide (LOS) have been identified.

133 Lipooligosaccharide (LOS) heptose (Hep) glycan substitut

134 The role of NTHi lipooligosaccharide (LOS) in adherence was examined usin

135 Biosynthesis of the variable core domain of lipooligosaccharide (LOS) in Neisseria gonorrhoeae is me

136 The sialylation of lipooligosaccharide (LOS) in Neisseria meningitidis play

137 of nontypeable Haemophilus influenzae (NTHI) lipooligosaccharide (LOS) in the induction of proinflamm

138 ed nontypeable Haemophilus influenzae (NTHi) lipooligosaccharide (LOS) in the pathogenesis of otitis

139 Both live H. ducreyi and purified H. ducreyi lipooligosaccharide (LOS) induced significant interleuki

140 Lipooligosaccharide (LOS) is a component of the gonococc

141 Lipooligosaccharide (LOS) is a major surface antigen of

142 Lipooligosaccharide (LOS) is a major surface antigen of

143 Lipooligosaccharide (LOS) is a major surface antigen of

144 Lipooligosaccharide (LOS) is a major surface component o

145 C. jejuni lipooligosaccharide (LOS) is a potent activator of Toll-

146 The lipooligosaccharide (LOS) is an outer membrane component

147 Haemophilus ducreyi lipooligosaccharide (LOS) is capable of inducing an infl

148 Campylobacter jejuni 81-176 lipooligosaccharide (LOS) is composed of two covalently

149 The lipooligosaccharide (LOS) is considered to be a major vi

150 ganglioside mimicry in Campylobacter jejuni lipooligosaccharide (LOS) is considered to be involved i

151 To determine how lipooligosaccharide (LOS) modifications would affect the

152 To begin to understand the role of the lipooligosaccharide (LOS) molecule in chancroid infectio

153 s both express the lacto-N-neotetraose (LNT) lipooligosaccharide (LOS) molecule that can be sialylate

154 Moraxella catarrhalis isolates express lipooligosaccharide (LOS) molecules on their surface, wh

155 A lipooligosaccharide (LOS) mutant of Neisseria meningitid

156 ct of a Haemophilus ducreyi pyocin-resistant lipooligosaccharide (LOS) mutant, HD35000R.

157 Neither lipooligosaccharide (LOS) nor lipid A could be isolated

158 Structural comparison of the lipooligosaccharide (LOS) of a lic2B mutant to that of t

159 The lipooligosaccharide (LOS) of H. influenzae has been impl

160 The lipooligosaccharide (LOS) of Haemophilus ducreyi contain

161 To define the role of the surface lipooligosaccharide (LOS) of Haemophilus ducreyi in the

162 The lipooligosaccharide (LOS) of Haemophilus ducreyi, the et

163 The lipooligosaccharide (LOS) of Haemophilus influenzae cont

164 The lipooligosaccharide (LOS) of Haemophilus somnus undergoe

165 In order to determine if the lipooligosaccharide (LOS) of M. catarrhalis has a role i

166 However, molecular mimicry of the lipooligosaccharide (LOS) of most C. jejuni strains with

167 ransferases involved in the synthesis of the lipooligosaccharide (LOS) of Neisseria gonorrhoeae.

168 Lipooligosaccharide (LOS) of Neisseria meningitidis is t

169 required for inner-core biosynthesis of the lipooligosaccharide (LOS) of Neisseria meningitidis.

170 de gel electrophoresis demonstrated that the lipooligosaccharide (LOS) of the galU mutant migrated fa

171 ined the effect of sialylation of gonococcal lipooligosaccharide (LOS) on MBL function.

172 The lipooligosaccharide (LOS) outer core represents a protot

173 of lacto-N-neotetraose-expressing gonococcal lipooligosaccharide (LOS) play an important role in inva

174 hosphoethanolamine on the lipid A portion of lipooligosaccharide (LOS) plays an important role in Tol

175 The lipooligosaccharide (LOS) present in the outer membrane

176 ningitidis utilizes capsular polysaccharide, lipooligosaccharide (LOS) sialic acid, factor H binding

177 ), factor H (fH) binding protein (fHbp), and lipooligosaccharide (LOS) sialylation.

178 most serotypes, which was homologous to the lipooligosaccharide (LOS) sialyltransferase gene, lst, o

179 nd a range of isogenic mutants revealed that lipooligosaccharide (LOS) structure and capsulation infl

180 NANA is transferred primarily to a 4.5-kDa lipooligosaccharide (LOS) structure by a GC sialyltransf

181 corrected] Galbeta1 --> 4Glcbeta1 --> 4HepI) lipooligosaccharide (LOS) structure exclusively; the oth

182 N. meningitidis resulted in expression of a lipooligosaccharide (LOS) structure that contained only

183 beta-1,4 N-acetylglucosamine (Gal-GlcNAc)-R lipooligosaccharide (LOS) structure.

184 lic-3 and lgtC, that generate phase-variable lipooligosaccharide (LOS) structures.

185 Strain 35000HP produces a lipooligosaccharide (LOS) that contains D-glycero-D-mann

186 ic meningococcal case strains were of the L8 lipooligosaccharide (LOS) type; four of these were both

187 Neisseria meningitidis lipooligosaccharide (LOS) was a potent direct inducer of

188 the infectivity of gonococci with sialylated lipooligosaccharide (LOS) was compared with the infectiv

189 ulin G3), specific for Moraxella catarrhalis lipooligosaccharide (LOS) was evaluated for its function

190 s fH than those of their parent strains when lipooligosaccharide (LOS) was sialylated, whereas PorB m

191 the lacto-N-neotetraose (LNnT) structure on lipooligosaccharide (LOS) were phagocytosed by neutrophi

192 the causative agent of chancroid, produces a lipooligosaccharide (LOS) which terminates in N-acetylla

193 oethanolaminylation of lipid A on neisserial lipooligosaccharide (LOS), a major cell-surface antigen,

194 Lipooligosaccharide (LOS), a major outer membrane compon

195 Lipooligosaccharide (LOS), a major surface antigen of th

196 Lipooligosaccharide (LOS), a predominant surface-exposed

197 to an alternative outer membrane structure, lipooligosaccharide (LOS), because disseminated disease

198 eisseria meningitidis and sialylates surface lipooligosaccharide (LOS), facilitating resistance to co

199 aluate the impact on inflammation induced by lipooligosaccharide (LOS), Haemophilus influenzae type b

200 A major surface-exposed component of NTHi, lipooligosaccharide (LOS), is a virulence factor as well

201 size that multiple NTHi molecules, including lipooligosaccharide (LOS), mediate cellular interactions

202 Lipopolysaccharide, lipooligosaccharide (LOS), or endotoxin is important in

203 nic bacteria, truncation of surface glycans, lipooligosaccharide (LOS), or lipopolysaccharide (LPS) h

204 Various membrane markers including lipooligosaccharide (LOS), the 16-kDa outer membrane lip

205 predominant NTHI outer membrane protein, and lipooligosaccharide (LOS), the specific endotoxin of NTH

206 n C. jejuni suggest that all strains produce lipooligosaccharide (LOS), with about one-third of strai

207 netically and structurally defined capsule-, lipooligosaccharide (LOS)-, and sialylation-altered muta

208 adhesins, including structures found in the lipooligosaccharide (LOS).

209 type, including two that contained truncated lipooligosaccharide (LOS).

210 igenic and structural phase variation in its lipooligosaccharide (LOS).

211 cterium lost the ability to bind to purified lipooligosaccharide (LOS).

212 A major virulence factor is cell wall lipooligosaccharide (LOS).

213 lar rod protein, FlgG; the lipid A domain of lipooligosaccharide (LOS); and several N-linked glycans.

214 s with pathogenic Neisseria or with purified lipooligosaccharides (LOS) after previous exposure to LO

215 irected at a number of surface proteins, and lipooligosaccharides (LOS) and detoxified LOS may be an

216 Lipopolysaccharides (LPS) and lipooligosaccharides (LOS) are the main lipid components

217 nd contain outer membrane proteins (OMP) and lipooligosaccharides (LOS) in their natural conformation

218 . ducreyi culture supernatant and H. ducreyi lipooligosaccharides (LOS) induced IDO expression, which

219 the carbohydrate sialic acid into C. jejuni lipooligosaccharides (LOS) is associated with increased

220 Experiments utilizing endotoxin aggregates, lipooligosaccharides (LOS) isolated from metabolically l

221 Cell surface lipooligosaccharides (LOS) of H. ducreyi are thought to

222 The lipooligosaccharides (LOS) of Haemophilus ducreyi are hi

223 The outer cores of the lipooligosaccharides (LOS) of many strains of Campylobac

224 Neu5Gc can be incorporated into cell surface lipooligosaccharides (LOS) of nontypeable Haemophilus in

225 ccurring during NTHi disease is initiated by lipooligosaccharides (LOS) on the bacterial surface.

226 the etiologic agent of chancroid, expresses lipooligosaccharides (LOS) that are highly sialylated.

227 , NTHi has on its surface a diverse array of lipooligosaccharides (LOS) that influence host-bacterial

228 Neisseria gonorrhoeae make relatively large lipooligosaccharides (LOS) that structurally resemble hu

229 atty acid acylation, we compared endotoxins (lipooligosaccharides (LOS)) from hexa-acylated wild-type

230 of nontypeable H. influenzae is dominated by lipooligosaccharides (LOS), many of which incorporate si

231 2 strain which produces a complex mixture of lipooligosaccharides (LOS), the mutant strains 281.25 an

232 on in the oligosaccharide component of their lipooligosaccharides (LOS).

233 with different unusual free lipids, such as lipooligosaccharides (LOS).

234 performance of two EIAs (adsorption EIA and lipooligosaccharide [LOS] EIA) that detect antibodies to

235 sts (adsorption enzyme immunoassay [EIA] and lipooligosaccharide [LOS] EIA) to detect current Haemoph

236 Neisserial lipooligosaccharides (LOSs) are a family of complex cell

237 Lipooligosaccharides (LOSs) are cell surface-exposed gly

238 Neisseria gonorrhoeae lipooligosaccharides (LOSs) induce immunoglobulin G that

239 Unique glycolipids called lipopolysaccharide/lipooligosaccharide (LPS/LOS) are enriched in the cell-s

240 m-negative bacterial lipopolysaccharides and lipooligosaccharides (LPSs or LOSs, endotoxin) within in

241 nzae cannot incorporate sialic acid into its lipooligosaccharides, making the organism unable to surv

242 nally, these data suggest that the 1291 msbB lipooligosaccharide may suppress cytokine induction.

243 t are found in Campylobacter jejuni includes lipooligosaccharides mimicking human glycolipids, capsul

244 Analysis of lipooligosaccharide moieties using an enzyme-linked immu

245 matory responses elicited by the lptA mutant lipooligosaccharide more efficiently than those induced

246 wed no changes in sensitivity as a result of lipooligosaccharide mutations in oligosaccharide and lip

247 Neither purified lipooligosaccharide nor PorB from N. lactamica is likely

248 Purified lipooligosaccharide of C. jejuni appears to be the major

249 d with purified outer membranes and purified lipooligosaccharide of homologous infecting strains and

250 The lipooligosaccharide of N. gonorrhoeae has a hexa-acylate

251 s studies have shown that the outer membrane lipooligosaccharides of H. ducreyi contain terminal sial

252 few high-carbon sugars are also found in the lipooligosaccharides of the outer cell walls of Gram-neg

253 The major lipooligosaccharides of the sexually transmitted pathoge

254 We previously identified lipooligosaccharide on Neisseria meningitidis as an acce

255 tures by means of specific subpopulations of lipooligosaccharides on the bacterial surface that are d

256 eltaNspA Deltalst mutant unable to sialylate lipooligosaccharide or bind human fH via the known fH li

257 f sialic acid as a component of cell surface lipooligosaccharides or capsular polysaccharides has bee

258 The lipooligosaccharide, outer membrane protein patterns, an

259 pe- and species-specific glycopeptidolipids, lipooligosaccharides, phenolic glycolipids, and the genu

260 spectroscopy, the molecular elasticities of lipooligosaccharides present on NTHI cell surfaces were

261 ylglucosamine and distal sugars found in the lipooligosaccharide produced by the parental strain.

262 had similar outer membrane protein (OMP) and lipooligosaccharide profiles and growth rates except for

263 ad similar growth rates in broth and similar lipooligosaccharide profiles.

264 diator modulates the composition of the NTHI lipooligosaccharides, resulting in effects on biofilm ma

265 e degree of sialylation or expression of the lipooligosaccharide sialic acid acceptor, lacto-N-neotet

266 mbrane-bound factor H (fH; AP inhibitor) and lipooligosaccharide sialic acid, the meningococcal fH li

267 The aim of this study was to determine how lipooligosaccharide sialylation affects the serum sensit

268 Both endogenous and exogenous lipooligosaccharide sialylation are associated with incr

269 thesis genes synX and synC caused defects in lipooligosaccharide sialylation but not mutations in the

270 een polysialic acid capsule biosynthesis and lipooligosaccharide sialylation pathways in group B Neis

271 d in the loss of encapsulation and intrinsic lipooligosaccharide sialylation that may promote adheren

272 essential for survivability of NTHI in vivo, lipooligosaccharide sialylation was indispensable.

273 meningococcal fH ligands (fHbp and NspA) and lipooligosaccharide sialylation were deleted in all stra

274 isolates are rendered resistant in vitro by lipooligosaccharide sialylation.

275 and NspA (DeltafHbp DeltaNspA mutant) or the lipooligosaccharide sialyltransferase (Deltalst mutant)

276 main determinant of serum resistance in F62, lipooligosaccharide sialyltransferase (Lst).

277 is not fully understood, but alterations in lipooligosaccharide structure can affect such resistance

278 The hldA mutant has a truncated lipooligosaccharide structure, contains lipid A in its o

279 of selected surface-associated proteins and lipooligosaccharide structure, known to contribute to vi

280 ption of PhoPQ-mediated modifications to the lipooligosaccharide structure.

281 19 and two FA 19 derivatives with truncated lipooligosaccharide structures were more susceptible to

282 h plasmids containing Haemophilus influenzae lipooligosaccharide synthesis genes (lsg).

283 om m-Tn3(Cm) insertions into the 7.4-kb lsg (lipooligosaccharide synthesis genes) region of Hib DNA,

284 translation, and the inhibition of bacterial lipooligosaccharide synthesis.

285 protein and soluble CD14-induced delivery of lipooligosaccharides to endothelial cells and cell activ

286 structure of a recently identified bacterial lipooligosaccharide, to appear foreign to the immune sys

287 ins, polysialic acid capsule or a particular lipooligosaccharide variant.

288 2, HMW1/2, and Hap or expressing a truncated lipooligosaccharide was compared to that of parental str

289 forms were two- to fourfold greater when the lipooligosaccharide was derived from planktonic or biofi

290 cance of phosphoethanolamine extensions from lipooligosaccharide, we found that phosphoethanolamine s

291 n, FlgG, and the lipid A domain of C. jejuni lipooligosaccharide with a pEtN residue.

292 zae (NTHi) is dependent on the decoration of lipooligosaccharide with sialic acid.