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1 for lipoprotein lipase and very-low-density lipoprotein receptor.
2 oproteinase-9 pathway in pericytes through a lipoprotein receptor.
3 hibits cholesterol uptake by the low-density lipoprotein receptor.
4 regulating neuronal migration by binding to lipoprotein receptors.
5 gnition sequence in the cytoplasmic tails of lipoprotein receptors.
6 ran sulfate proteoglycans (HSPGs) as remnant lipoprotein receptors.
7 2 cm(2)+/-0.023 [n=9], P2X7(-/-) low density lipoprotein receptor(-/-) : 0.084 cm(2)+/-0.01 [n=11], P
9 labeled anti-lectinlike oxidized low-density lipoprotein receptor 1 antibody, which detects the lecti
10 detects the lectinlike oxidized low-density lipoprotein receptor 1 that is overexpressed on a variet
18 mice, which are deficient in the low-density lipoprotein receptor and in which hypercholesterolemia i
19 ering, with the discovery of the low-density lipoprotein receptor and its physiology and not only the
20 over, they reveal an unexpected link between lipoprotein receptor and sphingolipid signaling that, in
21 clearance of remnants occurs via low density lipoprotein receptors and the heparan sulfate proteoglyc
23 onger Sepp1 isoforms bind to the low density lipoprotein receptor apoER2, but the mechanism remains u
24 DH is caused by mutations in the low-density lipoprotein receptor, apolipoprotein B, or proprotein co
25 Ubiquitous blocking of LRP1 or additional lipoprotein receptors by overexpressing receptor-associa
26 acrophage by modulating oxidized low-density lipoprotein receptor CD36, phagolysosomal maturation blo
28 that the amino-terminal modular low-density lipoprotein receptor class A (LA) domains within HP14 ar
29 -coenzyme A reductase, and human low-density lipoprotein receptor), compared to uninfected controls.
31 cted deletion of DNGR-1 in Ldlr (low-density lipoprotein receptor)-deficient mice (Ldlr(-/-)) signifi
33 c lesions from high-fat diet-fed low-density lipoprotein receptor-deficient (Ldlr(-/-)) mice in a tim
34 radiated, atherosclerosis-prone, low-density lipoprotein receptor-deficient (Ldlr(-/-)) mice received
36 t cells in atherosclerosis-prone low-density lipoprotein receptor-deficient (Ldlr(-/-)) mice, we show
45 hways have been shown to protect low-density lipoprotein receptor-deficient mice (Ldlr(-/-)) from ear
46 f diet-induced insulin-resistant low-density lipoprotein receptor-deficient mice and of genetically o
47 d reduced steatosis in livers of low-density lipoprotein receptor-deficient mice fed a Western diet.
48 ecreased hepatic inflammation in low-density lipoprotein receptor-deficient mice on a Western-type di
49 e response pathways in livers of low-density lipoprotein receptor-deficient mice on a Western-type di
51 the AngII-infused hyperlipidemic low-density lipoprotein receptor-deficient mouse (LDLR(-/-)) model,
52 and insulin resistance in mice, low-density lipoprotein receptor-deficient, S100A9-deficient bone ma
54 exin type 9 (PCSK9) binds to the low-density lipoprotein receptor, escorting it to its destruction in
55 onarily conserved pathway for the control of lipoprotein receptor expression and cellular lipid uptak
57 tein 1 (LRP1) is a member of the low density lipoprotein receptor family and plays important roles in
58 -AP-2 and directs endocytosis of low density lipoprotein receptor family members by recognizing a pho
59 perone that binds LRP1 and other low density lipoprotein receptor family members in the endoplasmic r
60 eptor (VLDLR) is a member of the low-density lipoprotein receptor family that binds multiple ligands
61 liposomes utilize scavenger and low-density lipoprotein receptors for endocytosis and enter cells th
63 aising the expression of SREBP2, low-density lipoprotein receptor, HMGCo-A reductase, and the cholest
67 R/KR) mice are intercrossed with low density lipoprotein receptor knock-out mice (Ldlr(-/-)), they de
72 d PB-NLCs were investigated in a low density lipoprotein receptor knockout (LDLr-/-) mouse model, inc
73 n- (OVA-) sensitized C57BL/6 and low-density lipoprotein receptor knockout mice (LDLr(-/-)) for 5 wee
76 ve transfer of apop(ox)-DCs into low-density lipoprotein receptor knockout mice either before or duri
77 te T cell lipid composition and responses in lipoprotein receptor knockout mice even in the absence o
78 r leakage in the eyecups of very low-density lipoprotein receptor knockout mice, a model of subretina
83 ts an atheroprotective action on low density lipoprotein receptor (LDL-r(-/-)) female mice, but, in c
84 Investigation on the role of low-density lipoprotein receptor (LDL-R) as a hepatocyte surface rec
85 ulates surface expression of the low-density lipoprotein receptor (LDL-R), increasing serum LDL-C.
86 planted into lethally irradiated low density lipoprotein receptor Ldlr(-/-) mice on an atherogenic di
87 bit recognition of oxLDL by KCs, low-density lipoprotein receptor (Ldlr(-/-) ) mice were immunized wi
88 to mice that do not express the low density lipoprotein receptor (Ldlr(-/-)), which are hyperlipidem
89 a Western-type diet and lacking low-density lipoprotein receptor (Ldlr(-/-)T39(-/-)) show decreased
90 oss-of-function mutations in the low-density lipoprotein receptor (LDLR) and homozygous familial hype
92 owth factor-like-A domain of the low density lipoprotein receptor (LDLR) and mediates LDLR degradatio
93 ct of the treatments on cellular low-density lipoprotein receptor (LDLR) and proprotein convertase su
94 lly deficient iPSC utilizing the low-density lipoprotein receptor (LDLR) deficiency Familial Hypercho
96 ficiently blocked PCSK9-mediated low density lipoprotein receptor (LDLR) degradation in cell lines, i
97 n and receptors belonging to the low density lipoprotein receptor (LDLR) family, known to be involved
99 a patient with mutations in the low-density lipoprotein receptor (LDLR) gene that result in familial
100 e polymorphism in exon 12 of the low-density lipoprotein receptor (LDLR) gene, rs688, has been associ
101 thionine beta-synthase (CBS) and low-density lipoprotein receptor (LDLr) genes were deficient (Ldlr(-
102 rol and an overexpression of the low-density lipoprotein receptor (LDLR) in pancreatic tumor cells.
105 e recently demonstrated that the low-density lipoprotein receptor (LDLR) is a major apoE receptor in
109 osclerotic lesion macrophages of low-density lipoprotein receptor (Ldlr) knockout mice fed a Western
111 atients who already have reduced low-density lipoprotein receptor (LDLR) levels, such as those with h
118 te that modulating levels of the low-density lipoprotein receptor (LDLR), a cell surface receptor tha
119 ruits its cargoes, including the low-density lipoprotein receptor (LDLR), and mediates endocytosis, e
121 f the identified substrates, the low-density lipoprotein receptor (LDLR), ERdj5 is required not for d
122 N1), Occludin (OCLN), SR-BI, and low-density lipoprotein receptor (LDLR), function mainly at postatta
123 adhesion molecule-1 (ICAM-1) and low-density lipoprotein receptor (LDLR), inter- and intraspecies foo
124 fied 2 nonsynonymous variants in low-density lipoprotein receptor (LDLR), namely p.G116S and p.R730W.
125 eptor molecules CD81, claudin-1, low-density lipoprotein receptor (LDLr), occludin, and SR-BI did not
126 lisin/kexin type 9 (PCSK9) binds low-density lipoprotein receptor (LDLR), preventing its recycling.
127 of-of-principle, we targeted the low-density lipoprotein receptor (Ldlr), which when deleted, leads t
128 poprotein E (apoE)-deficient and low-density lipoprotein receptor (LDLR)-deficient mice that produce
129 sly demonstrated that macrophage low-density lipoprotein receptor (LDLR)-related protein 1 (LRP1) def
130 osine-protein kinase), and Lrp4 (low-density lipoprotein receptor (LDLR)-related protein 4), an LDLR
134 a IDOL and inducible degrader of low-density lipoprotein receptor [LDLR]), with LDL cholesterol stati
135 a mechanism that is dependent on low-density lipoprotein receptors (LDLRs) and LDLR-related protein 1
138 PCSK9 levels, increased hepatic low-density lipoprotein receptor levels, and decreased plasma choles
139 y showed that SERPINA3K binds to low-density lipoprotein receptor-like protein 6 (LRP6) with a K(d) o
145 s analyzed in aortic arches from low density lipoprotein receptor(-/-) mice consuming a high-choleste
147 lanted into irradiated recipient low-density lipoprotein receptor(-/-) mice, and atherosclerosis was
149 rotein-deficient (apoE(-/-)) and low-density lipoprotein receptor negative (LDLR(-/-)) mice (0.05 mmo
151 DS AND Paradoxically, Ldlr(-/-) (low-density lipoprotein receptor null) mice deficient in miR-146a de
152 ion size was found in Ldlr(-/-) (low-density lipoprotein receptor null) mice transplanted with bone m
153 ed atherosclerosis in irradiated low-density lipoprotein receptor null-recipient mice and in apolipop
156 Cre-IKKbeta-flox system rendered low density lipoprotein receptor-null mice resistant to vascular inf
157 ar smooth muscle lineage of male low-density lipoprotein receptor-null mice, a background susceptible
158 fied alpha2M delivers its misfolded cargo to lipoprotein receptors on macrophages and reduces Abeta1-
159 harboring targeting motifs from low-density lipoprotein receptor or neuron-glia cell-adhesion molecu
160 ermeability, whereas blockade of low-density lipoprotein receptors or exposed lysine residues resulte
161 rest to address drugs and contrast agents to lipoprotein-receptor-overexpressing cancer cells found i
163 arizes our current understanding of the role lipoprotein receptors play in CNS function and AD pathol
166 d dramatic reductions in hepatic low-density lipoprotein receptor protein and increased plasma low-de
167 n/kexin type 9 (PCSK9) regulates low density lipoprotein receptor protein levels by diverting it to l
168 veloped in these mice, LDLR(-/-)/low-density lipoprotein receptor Rag 1 double-knockout mice (lacking
171 in the liver can override other low-density lipoprotein receptor regulatory pathways leading to card
172 d pGSK-3beta(Ser9), unchanged pPDK1, pTau or lipoprotein receptor related protein 1 (LRP1), higher gl
173 mation involves Frizzled4 (Fz4), low-density lipoprotein receptor related protein 5/6 (Lrp5/6), Tetra
174 ed the phosphorylation of the Wnt coreceptor lipoprotein receptor related protein 6 (LRP6) and induce
175 nalization of Abeta bound to the low density lipoprotein receptor related protein-1, a key Abeta clea
176 1/2), to their cognate receptor, low-density-lipoprotein-receptor related protein 6 (LRP6), in the pl
177 distinct receptors, namely, the low-density lipoprotein receptor-related protein (LRP) and cell surf
179 healthy donors was decreased after blocking lipoprotein receptor-related protein (LRP), a CRT recept
180 ously reported that RanBP9 binds low-density lipoprotein receptor-related protein (LRP), amyloid prec
186 We achieve this by targeting the Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1) receptor.
187 MTS-5 is rapidly endocytosed via low density lipoprotein receptor-related protein 1 (LRP1) and degrad
188 ors for these secreted proteins, low-density lipoprotein receptor-related protein 1 (LRP1) and Integr
189 6535, located within intron 1 of low-density-lipoprotein receptor-related protein 1 (LRP1) demonstrat
190 clearance and signaling receptor low density lipoprotein receptor-related protein 1 (LRP1) in both pr
191 trated significant roles for the low-density lipoprotein receptor-related protein 1 (LRP1) in the met
197 lso requires the function of the low-density lipoprotein receptor-related protein 1 (LRP1), a major a
198 associated with its reduction in low-density lipoprotein receptor-related protein 1 (LRP1), an Abeta
199 d both alpha2M and its receptor, low-density lipoprotein receptor-related protein 1 (LRP1), in cultur
200 An Abeta clearance receptor, the low-density lipoprotein receptor-related protein 1 (LRP1), is abunda
201 apoE and sAbeta compete for the low-density lipoprotein receptor-related protein 1 (LRP1)-dependent
204 ecific interactions of apoE with low-density lipoprotein receptor-related protein 1 on brain vascular
206 s mRNA and protein expression of low density lipoprotein receptor-related protein 2 and alpha-synucle
207 ts with SNMG were retrospectively tested for lipoprotein receptor-related protein 4 (LRP4) antibodies
208 ain was impaired in mice lacking low-density lipoprotein receptor-related protein 4 (Lrp4), a protein
209 dentified autoantibodies against low-density lipoprotein receptor-related protein 4 (LRP4), an agrin
210 euromuscular synapses, and (iii) low-density lipoprotein receptor-related protein 4 (Lrp4), which res
211 ein acting downstream from agrin/low-density lipoprotein receptor-related protein 4 (LRP4)/MuSK, has
212 tified previously in vitro LRP4 (low-density lipoprotein receptor-related protein 4) as a facilitator
213 tein, which interacts with LRP4 (low-density lipoprotein receptor-related protein 4) to activate the
214 dentified novel functions of the low-density lipoprotein receptor-related protein 4-muscle-specific k
215 acid position (p.R1188W) in the low density lipoprotein receptor-related protein 5 (LRP5) gene segre
216 g ligand or receptors, including low-density lipoprotein receptor-related protein 5 (LRP5) gene.
217 yptophan hydroxylase 1 (Tph1) or low-density lipoprotein receptor-related protein 5 (Lrp5) that are i
219 mice in which a mutation in the low-density lipoprotein receptor-related protein 5 Wnt coreceptor ca
220 d the Wnt-activated Frizzled and low-density lipoprotein receptor-related protein 5/6 receptors and p
221 it binds to the Wnt co-receptor low-density lipoprotein receptor-related protein 6 (LRP6) in cellula
222 contributions of Wnt coreceptor low-density lipoprotein receptor-related protein 6 (LRP6) in the vas
225 induced by a constitutively active mutant of lipoprotein receptor-related protein 6 (LRP6) or beta-ca
226 Interactions between Cav-1 and low-density lipoprotein receptor-related protein 6 (LRP6) were repor
227 Additionally, inhibition of low-density lipoprotein receptor-related protein 6 (LRP6) with eithe
228 is gene 2, as well as coreceptor low density lipoprotein receptor-related protein 6 (LRP6), are marke
229 including the expression of the Wnt receptor-lipoprotein receptor-related protein 6 (LRP6), phosphory
230 and Wnt3a and the Wnt coreceptor low-density lipoprotein receptor-related protein 6 (LRP6), possibly
236 ch as frizzled homolog 7 (FZD7), low density lipoprotein receptor-related protein 6 and transcription
237 he E1E2 domain of Wnt coreceptor low-density lipoprotein receptor-related protein 6, Mab2F1, on canon
238 Fetal liver cells derived from low-density-lipoprotein receptor-related protein 6-deficient mice (L
239 e encoding WNT receptors (frizzled [FZD] and lipoprotein receptor-related protein [LRP] family member
240 pse number were mediated via the low-density lipoprotein receptor-related protein and subsequent Ca(2
241 (ADAM9), reticulon 4 (RTN4), and low-density lipoprotein receptor-related protein associated protein
242 ociated protein (an inhibitor of low density lipoprotein receptor-related protein function) and requi
244 tutions within LRP1B, encoding a low-density lipoprotein receptor-related protein tied to both the NM
245 on of eNOS was decreased by anti-low density lipoprotein receptor-related protein-1 (LRP) antibody an
246 ound that the endocytic receptor low density lipoprotein receptor-related protein-1 (LRP-1) plays a m
249 s including mannose receptor and low-density lipoprotein receptor-related protein-1 (LRP1) have been
250 scular hypothesis, impairment of low-density lipoprotein receptor-related protein-1 (LRP1) in brain c
254 giopep-2 (ANG), a ligand for the low-density lipoprotein receptor-related protein-1 (LRP1), has also
255 vation of beta1 integrin via the low density lipoprotein receptor-related protein-1 (LRP1), which lea
262 exin domain of MMP9 binds to the low-density lipoprotein receptor-related protein-1, triggers phospho
263 some-dependent degradation in an low-density lipoprotein receptor-related protein-1-dependent manner.
265 hat Wnt receptors (Frizzled4 and low-density lipoprotein receptor-related protein5 [Lrp5]) and activi
266 igand-binding antagonist for the low-density lipoprotein receptor-related proteins (LRPs), and siRNA-
267 a ligand for the WNT coreceptors low-density lipoprotein receptor-related proteins 5 and 6 (LRP-5 and
268 hese results complement our understanding of lipoprotein receptor-related proteins 5 and 6 (LRP5/6),
271 how that the soluble form of the low-density lipoprotein receptor relative, LR11/SorLA (sLR11), suppr
272 rotein E receptor 2 and the very low density lipoprotein receptor, resulting in the phosphorylation o
273 ion, and function of the murine high density lipoprotein receptor scavenger receptor class B type I (
274 itellogenin receptor Yolkless, a low density lipoprotein receptor superfamily member, occur; a functi
276 B type 1), encoded by the gene SCARB1, is a lipoprotein receptor that binds both high-density lipopr
277 also known as SorLA, is a mosaic low-density lipoprotein receptor that exerts multiple influences on
279 BI (SR-BI) and BII (SR-BII) are high-density lipoprotein receptors that recognize various pathogens,
280 th the RELN receptor VLDLR (very low-density lipoprotein receptor); this was confirmed by a RELN-bind
281 odies prevent the degradation of low density lipoprotein receptor, thus lowering serum levels of LDL-
282 venting the recirculation of the low-density lipoprotein receptor to the hepatocyte cell surface.
283 a 95-141) that separates the two low-density lipoprotein receptor type A (LDLR-A) domains does not af
286 a the lipoprotein receptors very low density lipoprotein receptor (VLDLR) and apolipoprotein E recept
287 n E receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR) and is internalized by cell
288 d that miR-200c targets the very low density lipoprotein receptor (Vldlr) and its ligand reelin, whic
289 Receptor 2 (ApoER2) and the very low density lipoprotein receptor (VLDLR) are type I transmembrane pr
292 viously, we have shown that very low density lipoprotein receptor (VLDLR) is virtually absent in prea
294 ding through the receptors, Very low-density lipoprotein receptor (Vldlr), Apolipoprotein receptor 2
295 in another Reelin receptor, very low-density lipoprotein receptor (VLDLR), had normal rod bipolar mor
297 another angiogenic model of very-low-density lipoprotein receptor (Vldlr)-deficient (Vldlr (-/-) ) mi
299 apparent effect of hypoxia on HSPGs, whereas lipoprotein receptors (VLDLR and SR-B1) were transiently
300 an interaction with VLDLR (very low-density lipoprotein receptor), while the APOER2 signaling pathwa
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