ライフサイエンスコーパス: liquid ventilation

1 verse events clearly attributable to partial liquid ventilation.

2 mproved during total, but not during partial liquid ventilation.

3 is improved during total followed by partial liquid ventilation.

4 entially better approach to applying partial liquid ventilation.

5 ge, allowing successful performance of total liquid ventilation.

6 de, intratracheal pulmonary ventilation, and liquid ventilation.

7 ning, tracheal gas insufflation, and partial liquid ventilation.

8 s of lungs from animals treated with partial liquid ventilation.

9 lation = 0.41 +/- 0.02 mL/cm H2O/kg, partial liquid ventilation = 0.47 +/- 0.08, p = .151).

10 = O.48 +/- 0.03 mL/cm H2O/kg, total/partial liquid ventilation = 0.50 +/- 0.17 mL/cm H2O/kg) were ob

11 with controls (pulmonary compliance: partial liquid ventilation, 0.43 +/- 0.04 mL/ cm H2O/kg; control

12 tilation = 0.43 +/- 0.03 mL/cm H2O/kg, total liquid ventilation = 1.13 +/- 18 mL/cm H2O/kg, p <.001;

13 al: gas ventilation 6 +/- 1 mL/cm H2O, total liquid ventilation 14 +/- 4 mL/cm H2O, p < .0001; surfac

14 ysiologic shunt after 50 mL/kg dose: partial liquid ventilation, 2 +/- 8%; control, 64 +/- 5%; p = .0

15 (gas ventilation = 89 +/- 7 mL/kg/min, total liquid ventilation = 22 +/- 10 mL/kg/min, p <.001; gas v

16 Ultrafast cooling with total liquid ventilation (32 degrees C within 5 min in the eso

17 s ventilation = 91 +/- 12 mL/kg/min, partial liquid ventilation = 41 +/- 11 mL/kg/min, p < .001).

18 ompared with the gas ventilated group (total liquid ventilation 44 +/- 17 mL, gas ventilation 2 +/- 8

19 animals (gas ventilation = 93 +/- 8%, total liquid ventilation = 45 +/- 11%, p<.001; gas ventilation

20 volume observed with gas ventilation (total liquid ventilation 50 +/- 14 mL, gas ventilation 4 +/- 9

21 p<.001; gas ventilation = 95 +/- 3%, partial liquid ventilation = 61 +/- 12%, p<.001), while static c

22 (gas ventilation = 69 +/- 11%, total/partial liquid ventilation = 71 +/- 3%) and a decrease in static

23 nt: gas ventilation 4 +/- 1 mL/cm H2O, total liquid ventilation 9 +/- 3 mL/cm H2O, p < .01).

24 al oxygen saturation after 50 mL/kg: partial liquid ventilation, 96 +/- 3%; control, 55 +/- 8%; p = .

25 ; d) CVF-PLV group, animals received partial liquid ventilation after cobra venom factor; e) CVF-PEEP

26 groups: surfactant alone (S; n = 8); partial liquid ventilation alone (PLV-only; n = 8); surfactant f

27 Later on, total liquid ventilation also mitigated the systemic inflammat

28 These data suggest that both partial liquid ventilation and PEEP result in a reduction in neu

29 kable biocompatibility, with applications in liquid ventilation and synthetic blood.

30 ventilator strategies, inhaled nitric oxide, liquid ventilation, and extracorporeal life support (ECL

31 After induction of lung injury, all partial liquid ventilation animals received intratracheal perflu

32 flammatory infiltration in the total/partial liquid ventilation animals when compared with the gas ve

33 ay pressure release ventilation, and partial liquid ventilation are potential protective ventilatory

34 pediatric, and adult--have been treated with liquid ventilation as part of clinical trials.

35 nspiratory and expiratory phase during total liquid ventilation at low respiratory rates, apparently

36 Partial liquid ventilation attenuates oxidative damage to lipids

37 ; b) PLV-CVF group, animals received partial liquid ventilation before the induction of lung injury;

38 information available from studies involving liquid ventilation, both laboratory-based and clinical t

39 Total liquid ventilation can elicit rapid cardioprotective coo

40 s were lower in animals treated with partial liquid ventilation compared with conventionally ventilat

41 onary blood flow is preserved during partial liquid ventilation compared with gas ventilation in olei

42 rate achieved 58% versus 0% and 8% in total liquid ventilation, control, and conventional cooling gr

43 Partial liquid ventilation, conventional mechanical ventilation,

44 d significance (p < .05) only in the partial liquid ventilation-conventional ventilation animals.

45 Partial liquid ventilation decreases pulmonary neutrophil accumu

46 d an oleic acid-induced lung injury: partial liquid ventilation during acute lung injury (OA-PLV) and

47 Animals treated with partial liquid ventilation exhibited attenuation of dinitropheny

48 rate was significantly lower in the partial liquid ventilation-flow interruption group (p < .05).

49 Animals treated with partial liquid ventilation-flow interruption had a significantly

50 quid ventilation (S-PLV; n = 8); and partial liquid ventilation-followed by surfactant (PLV-S; n = 8)

51 n=5) over the ensuing 2.5 hrs, or with total liquid ventilation for 1 hr, followed by partial liquid

52 id ventilation for 1 hr, followed by partial liquid ventilation for 1.5 hrs (total/partial liquid ven

53 Ten infants received partial liquid ventilation for 24 to 76 hours.

54 completed the study if they received partial liquid ventilation for at least 24 hours.

55 was significantly lower in the total/partial liquid ventilation group when compared with that of the

56 a induced by total liquid ventilation (total liquid ventilation group) or by combination of cold sali

57 Five animals (partial liquid ventilation group) underwent sequential intratrac

58 0 minutes of total liquid ventilation (total liquid ventilation group, n = 12) or IV cold saline (con

59 as achieved within 5-10 minutes in the total liquid ventilation group.

60 ter perflubron administration in all partial liquid ventilation groups.

61 Partial liquid ventilation, high-frequency ventilation, and inha

62 ) liquid, such as perflubron, during partial liquid ventilation improves lung function and also reduc

63 nuous positive-pressure ventilation (partial liquid ventilation) improves lung function in animals wi

64 onstrate the feasibility of performing total liquid ventilation in rodents.

65 We evaluated the technique of partial liquid ventilation in six pediatric patients with the ac

66 d to assess bacterial recovery after partial liquid ventilation in vivo in rabbits.

67 ased from baseline (before injury or partial liquid ventilation) in the most dependent areas of the l

68 Whether partial liquid ventilation is effective in the treatment of infa

69 Liquid ventilation is one of the most extensively studie

70 The partial liquid ventilation-jet ventilation group had the highest

71 Partial liquid ventilation leads to clinical improvement and sur

72 Ultrafast cooling by total liquid ventilation limits the post-cardiac arrest syndro

73 eatments or no treatment (control): modified liquid ventilation (MLV), intramuscular ampicillin, MLV

74 mals were assigned to receive either partial liquid ventilation (n = 16) with perflubron (18 mL/kg vi

75 iquid ventilation for 1.5 hrs (total/partial liquid ventilation, n=5).

76 k for comparison with newer therapies (i.e., liquid ventilation, nitric oxide).

77 groups: a normal group that received partial liquid ventilation (Normal-PLV) and two acute lung injur

78 to decipher the effect of hypothermic total liquid ventilation on the systemic and cerebral response

79 f) PLV only group, animals received partial liquid ventilation only; g) GV only group, animals recei

80 Partial liquid ventilation or conventional ventilation was conti

81 The partial liquid ventilation-oscillation group required higher mea

82 s had a tracheostomy tube designed for total liquid ventilation placed under anesthesia.

83 y oscillatory ventilation (HFOV) and partial liquid ventilation (PLV) also decrease lung injury and i

84 g opacification by perflubron during partial liquid ventilation (PLV) and extracorporeal membrane oxy

85 Patients undergoing partial liquid ventilation (PLV) are often monitored with pulmon

86 Partial liquid ventilation (PLV) has been shown to be an effecti

87 Partial liquid ventilation (PLV) improves oxygenation in several

88 onary neutrophil accumulation during partial liquid ventilation (PLV) in the setting of acute lung in

89 Partial liquid ventilation (PLV) with perflubron (PFB) has been

90 evaluated the safety and efficacy of partial liquid ventilation (PLV) with perflubron in adult patien

91 We evaluated the effects of partial liquid ventilation (PLV) with two different dosages of t

92 mpared the effects of surfactant and partial liquid ventilation (PLV), and the impact of administrati

93 Animals were assigned to receive partial liquid ventilation (PLV, n = 15) with perflubron (18 mL/

94 Treatment with perfluorochemical partial liquid ventilation (PLV: PP-5 or H-130) or conventional

95 Total liquid ventilation provides ultrafast and potently neuro

96 only; n = 8); surfactant followed by partial liquid ventilation (S-PLV; n = 8); and partial liquid ve

97 information known to the medical field about liquid ventilation still comes from the laboratory.

98 Experimental techniques include liquid ventilation, surfactant administration and extrac

99 haled nitric oxide, almitrine, prostacyclin, liquid ventilation, surfactant, and immune-modulating th

100 We tested whether total liquid ventilation (TLV) can be used to rapidly cool and

101 The ability of total liquid ventilation to enhance recruitment of atelectatic

102 ce of perflubron-filled lungs during partial liquid ventilation to treat acute respiratory distress s

103 3 hours of mild hypothermia induced by total liquid ventilation (total liquid ventilation group) or b

104 hermia induced by either 30 minutes of total liquid ventilation (total liquid ventilation group, n =

105 -phosphatidylcholine activity in the partial liquid ventilation treated- vs. control rabbits demonstr

106 The phospholipid content of the partial liquid ventilation treated- vs. the control rabbits demo

107 The lower lobes of all partial liquid ventilation-treated animals demonstrated less dam

108 All partial liquid ventilation-treated animals had less lung injury

109 In this animal model, partial liquid ventilation using conventional or high-frequency

110 Total followed by partial liquid ventilation was associated with a reduction in al

111 nsion of normal atelectatic lungs with total liquid ventilation was associated with an 11-fold increa

112 Total liquid ventilation was associated with an increase in pu

113 In the other three infants, partial liquid ventilation was discontinued within four hours in

114 Partial liquid ventilation was initiated by instilling perflubro

115 Partial liquid ventilation was instituted with perflubron (Liqui

116 Total liquid ventilation was performed for 3 hrs with 20 mL.kg

117 Total liquid ventilation was performed with a pressure-limited

118 of the perfluorocarbon-filled lungs (partial liquid ventilation) was then performed.

119 ications potentially associated with partial liquid ventilation were limited to pneumothoraces in two

120 onary compliance was observed during partial liquid ventilation when compared with controls (pulmonar

121 which gas exchange is improved during total liquid ventilation when compared with gas ventilation in

122 y following attempted reexpansion with total liquid ventilation when compared with gas ventilation in

123 gnificantly reduced during total and partial liquid ventilation when compared with physiologic shunt

124 d beyond 28 days after initiation of partial liquid ventilation whereas 5 patients survived to discha

125 aled nitric oxide, aerosolized vasodilators, liquid ventilation) will require further research.

126 entional gas ventilation (n = 8); b) partial liquid ventilation with conventional ventilation (n = 7)

127 requency oscillation (n = 7); and e) partial liquid ventilation with high-frequency flow interruption

128 conventional ventilation (n = 7); c) partial liquid ventilation with high-frequency jet ventilation (

129 requency jet ventilation (n = 7); d) partial liquid ventilation with high-frequency oscillation (n =

130 requency oscillatory ventilation and partial liquid ventilation with perfiubron was well tolerated he

131 nventional mechanical ventilation or partial liquid ventilation with Perflubron (18 mL/kg by bolus fi

132 We conclude that partial liquid ventilation with Perflubron appears to have no ne

133 We studied the efficacy of partial liquid ventilation with perflubron in 13 premature infan

134 Partial liquid ventilation with perflubron provides effective im

135 unction of expiratory flow rate during total liquid ventilation with perflubron.

136 Liquid ventilation with perfluorocarbon previously has n

137 flammatory activity and suggest that partial liquid ventilation with PFC may be considered in future

138 d whole-body cooling can be induced by total liquid ventilation with temperature-controlled perfluoro

139 Partial liquid ventilation with the perfluorochemical, perflubro