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   1 nerally consistent with the known profile of lisdexamfetamine.                                       
  
  
     4 inge eating and related psychopathology, and lisdexamfetamine and topiramate reduced weight in adults
  
  
  
  
  
  
    11 pen-label phase (dose optimization, 4 weeks [lisdexamfetamine dimesylate, 50 or 70 mg]; dose maintena
    12  12) were randomized to placebo or continued lisdexamfetamine during a 26-week, double-blind, randomi
  
  
  
    16 sdexamfetamine responders (placebo, n = 138; lisdexamfetamine, n = 137), the observed proportions of 
  
    18 e, 50 or 70 mg]; dose maintenance, 8 weeks), lisdexamfetamine responders (</=1 binge eating day per w
  
  
    21  months was lower in participants continuing lisdexamfetamine than in those randomized to placebo.   
    22 system arousal occurred more frequently with lisdexamfetamine than placebo (relative risk range, 1.63
  
    24 ased on a Cox proportional hazards model for lisdexamfetamine vs placebo, was 0.09 (95% CI, 0.04-0.23
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