ライフサイエンスコーパス: lispro

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1 te of hypoglycemia was 12% less with insulin lispro (6.4 +/- 0.2 vs. 7.2 +/- 0.3 episodes/30 days, P

2 Insulin lispro, an insulin analog recently developed particularl

3 We compared insulin lispro and regular human insulin in the mealtime treatme

4 ve types of insulin (human, bovine, porcine, Lispro, and Lantus) were used as model products in the s

5 tudies employed Lys(B28), Pro(B29)-insulin ("lispro") as a model prandial analog that is less thermod

6 No evidence was noted that insulin lispro differs in immunogenicity from RHI in previously

7 In conclusion, insulin lispro improves postprandial control, reduces hypoglycem

8 largine, both combined with prandial insulin lispro, in patients with type 2 diabetes.

9 tiated, including human insulin (P28K29) and Lispro insulin (K28P29), which differ only by the interc

10 ed as prandial insulin (for example, insulin lispro, insulin aspart, or insulin glulisine) and basal

11 tors (glimepiride, insulin glargine, insulin lispro, liraglutide, pioglitazone, or sitagliptin).

12 Insulin lispro [Lys (B28), Pro (B29) human insulin] is a rapidly

13 For patients receiving insulin lispro, no significant changes occurred in antibody stat

14 glargine once daily and rapid-acting insulin lispro or aspart before meals (the basal-bolus group) du

15 ents were randomly assigned to begin insulin lispro or continue on RHI.

16 2.0 mmol/l in patients treated with insulin lispro (P < 0.001).

17 Dulaglutide in combination with lispro resulted in a significantly greater improvement i

18 f insulin-specific antibodies (ISA), insulin lispro-specific antibodies (LSA), and cross-reactive ant

19 sotherm) is approximately twice as large for Lispro than for porcine insulin.

20 hypoglycemic episodes was less with insulin lispro than with regular human insulin therapy during th

21 ucose was significantly lower during insulin lispro therapy.

22 ting this allosteric switch, 3-iodo-Tyr(B26)-lispro thus illustrates how a nonstandard amino acid sub

23 t tyrosine adjoining the engineered sites in lispro (Tyr(B26)) by 3-iodo-Tyr (i) augments its thermod

24 we contrasted the immunogenicity of insulin lispro versus regular human insulin (RHI) in patients pr

25 Insulin lispro was injected immediately before the meal, and reg

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