ライフサイエンスコーパス: little

1 However, we know little about how modern stormwater management practices

2 re well documented, but we know surprisingly little about how these pathways are coordinated when cel

3 Yet, we still know little about the ecology of chytrids, their life cycles,

4 mimicry is a striking phenomenon but we know little about the evolution of this trait in any species.

5 can be corrected essentially completely with little added computational cost.

6 In contrast, there was very little agonist action of I942 towards EPAC2 or protein k

7 With little and inconsistent information in the literature re

8 The in-plane symmetry breaking has little apparent connection to the underlying lattice, as

9 Many exotic species have little apparent impact on ecosystem processes, whereas o

10 e of spores, the exposure was detected in as little as 1 h without the use of antibodies or fluoresce

11 indow from approximately 5 nucleotides to as little as 1-2 nucleotides.

12 ely detected unique haplotypes comprising as little as 2% of a polyclonal infection.

13 DEEPER-Seq can create NGS libraries from as little as 20 pg DNA with PCR error correcting capabiliti

14 re peptides per protein and starting from as little as 200 mul of plasma.

15 of deuteration in the carbon source, and as little as 5% deuteration can be distinguished by analysi

16 n be reliably quantified, evidencing that as little as a few tens of copies of redox-labeled macromol

17 ent information is represented neurally, but little asks how even unintended harms influence judgment

18 dipole interactions that has so far received little attention compared to ion-ion interactions (salt

19 uorinated poly(aryl thioethers) has received little attention compared to the corresponding poly(aryl

20 Little attention has been given to how the asymmetric li

21 ent properties have been studied rigorously, little attention has been paid to the formation of singl

22 ve rise to domesticated rice, but relatively little attention has been paid to the origins and histor

23 Protein tyrosine phosphatases have received little attention in the study of SSc or fibrosis.

24 inal microbiota to this balance has received little attention.

25 healthcare outcomes and quality has received little attention.

26 robically germinating embryos, when there is little cell division.

27 lementation of the outcome measure must have little chance of inducing unintended adverse consequence

28 Although there was little change in CaN expression and localization after i

29 -130 cells per muL (range -472 to 266) with little change in CD4 cell percentage (-2.1%, range -8.4

30 convert the fast ions to neutral atoms with little change in momentum, transform these to a bright s

31 e to the use of diesel particle filters, but little change is seen in nitrogen dioxide over the perio

32 The widespread infection of these weeds by little characterised and persistent viruses and their po

33 There is also little clinical guidance for the use of these drugs and

34 ies claiming transgenerational impacts, with little compelling evidence.

35 However, there is little consensus about the factors that lead to umbilica

36 to evaluate the impact of hearing loss, with little consensus among researchers as to either preferen

37 inistration for major surgery, there remains little consensus on optimal strategies, due to the lack

38 individuals in an aging population, there is little consensus regarding its precise anatomic definiti

39 effects on ocean productivity have received little consideration aside from polar areas subject to p

40 almost entirely through AMPA receptors with little contribution from entry through NMDA receptors or

41 ccurs via a free radical mechanism with very little contribution from polar effects.

42 The study showed little correlation between HDL-C levels and asymptomatic

43 HF) disproportionately affects older adults, little data exist regarding the prevalence of American C

44 itions is challenging and there is currently little data from the wild.

45 of double radical MYBPC3 mutations, there is little data to guide clinical decision making in cases w

46 er complex state spaces, (b) learn with very little data, and (c) bridge long-term dependencies betwe

47 Surprisingly, there was very little difference between the two proteomes under standa

48 djustment for socio-demographic factors made little difference to these associations but a further ad

49 e glutamates to make GC-A-9E or GC-A-10E had little effect on activity, and sequential deletion of in

50 ion of the MLL1-4/COMPASS family members has little effect on early Hox gene activation.

51 onversely, nAChR activation appeared to have little effect on evoked responses from inhibitory thalam

52 circulating noradrenaline concentration had little effect on HR, potentially reflecting down-regulat

53 , potassium, and phosphorus content, but had little effect on other trace- and macro-nutrient element

54 Surprisingly, chronic hyperglycemia had little effect on primary T-cell reactivity after alloimm

55 tion on the aromatic rings had comparatively little effect on quadricyclane lability, substitution at

56 We find that the deletion of LMP2A alone has little effect on the ability of EBV to cause lymphomas b

57 (CI 6.1%, 20%), and accounting for them had little effect on the long-term association between SBP a

58 native interpretations of the trace call had little effect on these ratios.

59 ppressed by another set of stimuli that have little effect when presented in isolation.

60 For two nonamino acid buffers, TRIS had little effect while HEPES resulted in a 40 times lower r

61 ate feeding behavior, whereas inhibition has little effect, suggesting parallel pathways.

62 as changes in visual lead-in variability had little effect.

63 mes that do not alter polySia expression had little effect.

64 tal C-terminal-specific antibody (Tau46) had little effect.

65 Behavioural interventions alone have shown little efficacy, indicating limited success in modulatin

66 weeks, how often have you felt tired or had little energy?' Univariate GCTA-GREML found that the pro

67 in single food oral immunotherapy, there is little evidence concerning the safety and efficacy of tr

68 Moreover there is very little evidence for the cost-effectiveness of changing c

69 Our findings provide little evidence of a causal association between smoking

70 There is little evidence that CNI-sparing/minimization strategies

71 Moreover, we found little evidence that miRNAs previously shown to be assoc

72 Overall, there is little evidence that the program expansion improved air

73 h deep-sea data from the same region suggest little exchange of Operational Taxonomic Units (OTUs) be

74 ants (CNVs) on Type 2 Diabetes (T2D) remains little explored.

75 Relatively isolated subpopulations benefit little from high surrounding population immunity to tran

76 f individual studies or chemical experience, little has been done so far to systematically assess the

77 s or resistant genes in general, but provide little help in prioritizing and identifying gene cluster

78 Little however is known about the ancestry and history o

79 Little, however, is known about the mechanisms that medi

80 e regularly snow covered in winter, there is little hydro-climatologic knowledge in the cities impact

81 stent southward shift of the ITCZ during the Little Ice Age until the beginning of the 19th Century.

82 re than 2 decades ago, these discussions had little impact on epidemiologic practice.

83 Sample weighting approaches had little impact on field-estimated trait responses to elev

84 at introducing a bias toward GDP tubulin has little impact on the observed MT stabilization.

85 rmeability ratio of CFTR from 0.4 to 1.0 had little impact upon either the secreted HCO3(-) concentra

86 urfuryl alcohol formation was found to be of little impact.

87 natural organic matter (NOM) has relatively little impact.

88 We found that activation of the CSAR evokes little increase in cardiac contractility with an exagger

89 e., they can be combined and compounded with little increase in complexity), and "hackable" (i.e., th

90 cance and, despite excellent power, provided little independent confirmation of previously published

91 Despite their relevance little information about physicochemical characteristics

92 ation has been extensively studied, there is little information about resistance of skin microbiota i

93 onal alpha1-adrenergic ligands, yet there is little information describing this drug class at the alp

94 Very little information exists for long-term changes in genet

95 However, there is very little information on how the clock influences the perfo

96 eillance in reducing mortality, and there is little information on the harms available to patients co

97 To date, little information on the Vif-A3H interface has been ava

98 However, so far there is only little information regarding the ionization and fragment

99 e size in mammals and birds shows remarkably little interspecific variation compared with other taxa.

100 Consequently, very little is currently known about how expression of Eya1 i

101 ntexts on adults and older individuals, very little is currently known regarding regional changes in

102 lly distinct and experimentally dissociable, little is known about ambiguity sensitivity in individua

103 Little is known about bone mineral density (BMD) during

104 Relatively little is known about changes in bee community compositi

105 differences have been known for decades, yet little is known about differences at the fine scale.

106 However, little is known about disease progression, viral spread,

107 box or focussed on specific groups, whereas little is known about entire soil networks.

108 Relatively little is known about factors that initiate immunosuppre

109 ant Arabidopsis (Arabidopsis thaliana), very little is known about floral induction in tulip.

110 hippocampus supports memory encoding [1, 2], little is known about hippocampal activity during sponta

111 Little is known about how and where effectors are secret

112 Very little is known about how archaeal cells orchestrate tra

113 ed glucose causes beta-cell dysfunction, but little is known about how cells handle excess fuels to a

114 However, little is known about how cells sense and respond to mec

115 Little is known about how donor factors, timing of procu

116 pathogen exposure and epithelial injury, yet little is known about how enteropathogens may circumvent

117 However, little is known about how genes are specifically affecte

118 Little is known about how genetic variation and epigenet

119 At present, relatively little is known about how growth cone collapse occurs pr

120 spite more than a century of research on HR, little is known about how it is so tightly regulated and

121 However, surprisingly little is known about how LMP1 expression is regulated i

122 In human cells, little is known about how long noncoding RNAs (lncRNAs)

123 st majority of protein-encoding transcripts, little is known about how miRNAs themselves are degraded

124 by nucleoid-associated proteins (NAPs), but little is known about how NAP activity is coupled to cel

125 However, relatively little is known about how slow hemodynamic oscillations

126 However, very little is known about how stress response, neural proces

127 However, little is known about how the activity of these proteins

128 s are fairly well understood, but relatively little is known about how the extracellular matrix (ECM)

129 Little is known about how the proportions of dependency

130 However, little is known about how these cathelicidins affect TLR

131 ic relays on their way to a destination, but little is known about how these relays form and the func

132 mones, and neurotransmitters, but relatively little is known about how they are formed.

133 However, little is known about how this is happening in practice

134 However, little is known about how viruses resist IFITM inhibitio

135 fied by different fatty acids; however, very little is known about how zDHHC enzymes contribute to ac

136 Little is known about immune-modulatory effects of nilot

137 n terrestrial environments but comparatively little is known about interactions between microplastics

138 valent amyloid found to date, but remarkably little is known about it.

139 using acute respiratory illnesses and so far little is known about its biology.

140 of the primary drivers of species loss, yet little is known about its effect on other components of

141 However, little is known about its effects on humans.

142 NMD machinery is conserved between kingdoms, little is known about its evolution.

143 molecular characteristics of the scar, very little is known about its mechanical properties.

144 udies have demonstrated its high prevalence, little is known about its potential consequences on visu

145 Little is known about its role in the nervous system.

146 However, little is known about mechanisms and effector molecules

147 Little is known about mechanisms that restrain IL-17 cyt

148 rm a family of anion channels in plants, but little is known about most of its members.

149 nd spike frequency adaptation but relatively little is known about PIP2 's control of these AHPs.

150 Little is known about placental vitamin D metabolism and

151 However, little is known about posttranscriptional regulation of

152 in neuronal excitability have been observed, little is known about specific changes within neuronal e

153 fect of synaptic activation on beta-amyloid, little is known about Tau protein.

154 Furthermore, little is known about the allergen molecules causative f

155 Little is known about the association between structural

156 during adult in-hospital cardiac arrest, but little is known about the association between tracheal i

157 role in regulating harmful algal blooms, but little is known about the biochemical and physiological

158 c LCs have been characterized biochemically, little is known about the biology of amyloidogenic plasm

159 ffer across the general population; however, little is known about the brain characteristics supporti

160 as9 structures and its functional mechanism, little is known about the catalytic state of the Cas9 HN

161 posity by affecting developmental processes, little is known about the chemicals' effects on adult ad

162 ance of this layer of complexity, relatively little is known about the compositional heterogeneity of

163 Little is known about the cost-effectiveness of this app

164 However, little is known about the direct impact of transplanted

165 s also concentrated at the dendritic spines, little is known about the direct physiological functions

166 However, unlike for individual components, little is known about the distributions of mutational ef

167 e potential on the timescale of seconds, and little is known about the downstream effects from this m

168 Little is known about the drug survival of second-line b

169 oving catalyst activity and selectivity, yet little is known about the dynamic compositional and stru

170 Little is known about the effectiveness of contemplative

171 Little is known about the efficacy of the combination of

172 lopment of small-molecule therapeutics, very little is known about the environmental factors associat

173 However, little is known about the factors influencing GCC thickn

174 Little is known about the function of the cholinergic ef

175 Little is known about the functional development of indi

176 ual perceives the world in a unique way, but little is known about the genetic basis of variation in

177 However, little is known about the genetic structure and changes

178 In contrast to adult MDS, little is known about the genomic landscape of pediatric

179 Little is known about the health effects of school class

180 Little is known about the impact of another testing stra

181 However, little is known about the impact of cytoreductive chemot

182 elds from biology to computer science, still little is known about the impact of environmental change

183 imary sensitizer, whereas in Central Europe, little is known about the importance of LTP sensitizatio

184 Little is known about the in vivo fate of drug particles

185 Relatively little is known about the in vivo functions of newly eme

186 However, little is known about the interaction partners of PRMT7.

187 ls may play a role in viral persistence, but little is known about the kinetics of the generation, th

188 Little is known about the mechanism and structure of thi

189 d generation of reactive oxygen species, but little is known about the mechanism of their early invol

190 However, little is known about the mechanism(s) by which this fee

191 ritical importance for our daily activities, little is known about the mechanisms driving the develop

192 e advantage under conditions of hypoxia, but little is known about the mediators of this effect.

193 However, little is known about the metabolic changes that epimast

194 in injury associated with preterm birth, but little is known about the microglial response in preterm

195 However, little is known about the molecular and cellular determi

196 Little is known about the molecular mechanisms driving v

197 hat AM induces internalization of CLR*RAMP2, little is known about the molecular mechanisms that regu

198 pite its central role in protein degradation little is known about the molecular mechanisms that sens

199 crucial initiators of immune responses, but little is known about the molecular pathways used by DCs

200 In contrast to a wealth of human studies, little is known about the ontogeny and consistency of em

201 unctions in the context of inflammation, but little is known about the potential functions of C3 on r

202 rtunity for clean energy via hydropower, but little is known about the potential impact of dam-buildi

203 However, little is known about the predictive value of frequently

204 However, little is known about the production source of ET-1 in i

205 ost terminals in the central nervous system, little is known about the regulation of their AP shape d

206 However, little is known about the regulatory mechanisms of ILC2s

207 However, little is known about the role of bat ectoparasites in t

208 rins during cell spreading and motility, but little is known about the role of EGFR in these mechanos

209 role in differential progression to CCC, but little is known about the role of epigenetic modificatio

210 s response to chemotherapy and radiotherapy, little is known about the role of histone expression in

211 tulated as essential for normal development, little is known about the specific functions of the diff

212 However, little is known about the specific relationship between

213 ed predominately of the protein Ribeye, very little is known about the structural dynamics of ribbons

214 t role in extracellular matrix biosynthesis, little is known about the structural requirements of LOX

215 ompanied by orofacial motor dysfunction, but little is known about the structural substrates accounti

216 Little is known about the sustained or slowly reversible

217 Little is known about the TL1A-response pathways that re

218 e of mortality in HFpEF is sudden death, but little is known about the underlying mechanisms.

219 o the insulin promoter are known, relatively little is known about the upstream regulators of insulin

220 However, little is known about their association with outcomes in

221 e been shown to inhibit HIV/SIV replication, little is known about their expression in vivo Expressio

222 ins is one of the largest in eukaryotes, but little is known about their function in brain developmen

223 However, little is known about their functions in parasitic nemat

224 contribute to gene expression complexity but little is known about their impact on translation.

225 manifest as a reaction to new drug use, but little is known about their incidence and epidemiology.

226 underlie many learning and memory processes, little is known about these properties specifically on c

227 Little is known about these small RNAs in litchi (Litchi

228 thway and the energy metabolism pathway, but little is known about this cross-regulation.

229 However, little is known about whether and how long-range cross-f

230 Little is known about whether and how these RecQ helicas

231 However, little is known about whether depression affects individ

232 c cardiac repair and healing after ischemia, little is known about whether T cells directly impact ca

233 To date, little is known about whether the ERN can inform the cho

234 Little is known about which lesion subtypes may serve as

235 nflammatory mechanical hypersensitivity, yet little is known as to the post-translational mechanism b

236 viruses are transmitted via insect vectors, little is known at the molecular level as to how the vir

237 Little is known of how unique PNG mechanisms arose and e

238 Little is known of the mechanism of triplet microtubule

239 However, they are under researched and little is known of their impact on patients' lives.

240 anism leading to abnormal tooth development, little is known regarding how hypomorphic enamel is form

241 iated rolling have been extensively studied, little is known regarding how tumor cell rolling on sele

242 ll line or a published flea genome sequence, little is known regarding R. typhi biology in flea vecto

243 Yet little is known regarding the direct effects of IL-4 on

244 Little is known whether PH heightens the risk of heart f

245 Little is known, however, about the assembly mechanism a

246 Little is known, however, about the termination kinetics

247 Little is known, however, how transcranial current stimu

248 Furthermore, little is understood about the early events in the estab

249 their physical and chemical properties, but little is understood about the morphology and dynamics o

250 ppocampal CA2 and CA3 regions, but there are little known about their physiological function.

251 sease and Parkinson's disease, to relatively little loss, as seen in progressive supranuclear palsy.

252 f C-H bonds have been reported recently, but little mechanistic data on these processes are available

253 This result suggests that quantitatively little methylation or demethylation occurs in cytoplasmi

254 age of 50; however, the known genes explain little of the heritability.

255 ion differentiation rate explains relatively little of the variation in speciation rate among lineage

256 Little or no attention is placed on the environmental im

257 m, causing disease of variable severity with little or no direct systemic effects.

258 tic region, the transition was gradual, with little or no genetic input from incoming farmers [7].

259 g patients who are ethnic minorities or have little or no health insurance.

260 nt allergenic proteins are standardized with little or no information about compositional differences

261 location of the stimulus, but they provided little or no information about orientation independently

262 For example, many larvae display little or no movement.

263 Too little or too much iron can have important clinical cons

264 re RpoE activity was elevated expressed very little pertussis toxin.

265 on in folate levels among tomato accessions, little polymorphism was found in folate biosynthesis gen

266 Little progress has been made searching for risk-causati

267 deer populations, a factor that has received little research attention in recent years, despite its r

268 y, empathy, psychotherapy), but surprisingly little research has been aimed at identifying the effect

269 e a rich source of polyphenols, but there is little research on their postprandial effects.

270 There is little room for cropland expansion to increase productio

271 The revised 4-item Little Schmidy, the LS4, predicts pediatric falls when a

272 that had a common Zn(2+) bimetallo core but little sequence similarity and different auxiliary domai

273 that the gills of a cartilaginous fish, the little skate (Leucoraja erinacea), are in fact endoderma

274 While causing little skin irritation, vaccination efficacy of BCG-MNAs

275 heres required for song production have been little studied.

276 There has been relatively little study of posttraumatic stress disorder or obsessi

277 Nevertheless, very little success was achieved in the realization of electr

278 We found little support for the alternative hypothesis that fores

279 and Subantarctic Zones during the LGM, with little surface nitrate transport between them.

280 ) MPhi expressed IL-10R, CD206, and CCR2 but little TNF-alpha or CX3CR1.

281 unctional and nonfunctional Envs contributes little to HIV infection of human lymphoid tissue ex vivo

282 -0.10 to 0.24; moderate certainty evidence), little to no difference in proportion stunted (eight few

283 Additionally, knockdown of hgrs-1 had little to no effect on SNX-1 and RME-8 microdomains, sug

284 nhibition initiated 1 week post-I/R provided little to no further protection in mice with ablation of

285 tted helminths compared with controls led to little to no improvement in weight over a period of abou

286 ngth viral RNA abundance or distribution had little-to-no net effect on Gag assembly competency when

287 There is currently little understanding of how initial community structure

288 There is little understanding of mechanisms enabling defense meta

289 es in Southern Ocean food webs, but there is little understanding of the factors influencing its succ

290 however, the regulation of HSJ1 function is little understood.

291 complementary marker linkage maps that have little use in disease association analysis and breeding.

292 pproved more than a decade ago but have been little utilized because of a variety of medical, financi

293 Little variation among watersheds in potential spawning

294 Injection of ATP at 150 mum caused little Wallerian degeneration and behavioral tests showe

295 Very little was previously known about how the carboxymethyla

296 mporaneous with humans for almost a century, little was recorded about its ecology.

297 Tail handled mice showed little willingness to explore and investigate test stimu

298 iquid, the activation energy for eta changes little with cooling towards the glass transition tempera

299 However, little work has been done to optimize such transplantati

300 oratory accomplished this feat; without them little would have been done.