ライフサイエンスコーパス: liver X receptor alpha

1 roxylase, and the oxysterol nuclear receptor liver X receptor alpha.

2 ncoupling protein-1, or transcription factor liver X receptor-alpha.

3 Recently, we identified an enrichment of liver X receptor alpha and beta (LXRalpha/beta) in the n

4 o 6-fold increases in foam cells of mRNA for liver X receptor alpha and cholesterol efflux factors AB

5 The oxysterol receptors LXR (liver X receptor)-alpha and LXRbeta are nuclear receptor

6 Liver X receptor-alpha and -beta are members of the nucl

7 ator-activated receptor-alpha and -delta and liver X receptor-alpha and -beta mRNAs were detected in

8 Whereas both liver X receptor-alpha and liver X receptor-beta are exp

9 l regulatory element-binding protein-1c, and liver X receptor-alpha and the expression of their targe

10 is; (ii) whether this effect is mediated via liver X receptor-alpha and/or liver X receptor-beta; and

11 The liver X receptors alpha and beta (LXRalpha and LXRbeta)

12 egulated by the nuclear oxysterol receptors, liver X receptors alpha and beta (LXRalpha and LXRbeta).

13 2-related factor 2 (NRF2) but not on nuclear liver X receptors alpha and beta (LXRalpha,beta), peroxi

14 MASs serve as ligands for liver X receptors alpha and beta(LXRalpha and LXRbeta),

15 CD68, SR-AI, liver-X-receptor-alpha, and PPARgamma were regulated in

16 liferator-activated receptor (PPAR)gamma and liver-X-receptor-alpha, and the cholesterol efflux pump

17 me proliferator-activated receptor alpha and liver X receptor alpha as well as with the circadian osc

18 ompanied by a significant stimulation of the liver X receptor alpha-ATP-binding cassette transporter

19 alpha activity (z = 2.0, P = 6.6 x 10(-7)), liver X receptor alpha/beta agonism (z = 2.1, P = 2.8 x

20 e proliferator-activated receptor gamma, and liver X receptor alpha but was unable to reduce accumula

21 The level of liver X receptor alpha expression correlated directly wi

22 Retroviral expression of liver X receptor alpha in human breast cancer MDA-MB435S

23 ome proliferator-activated receptor alpha or liver X receptor alpha knockout mice were exposed to str

24 Liver X receptor alpha (LXR alpha) agonists and a high c

25 us work has implicated the nuclear receptors liver X receptor alpha (LXR alpha) and LXR beta in the r

26 adipocyte genes and chose one of these, the liver X receptor alpha (LXR alpha), for further analyses

27 e present study, we investigated the role of liver X receptor alpha (LXR(alpha)) and LXR(beta) in the

28 In addition, nuclear liver x receptor-alpha (LXRa), also regulated by TH, ind

29 The nuclear receptors liver X receptor alpha (LXRalpha) (NR1H3) and LXRbeta (N

30 Dysregulation of liver X receptor alpha (LXRalpha) activity has been link

31 The nuclear hormone receptors liver X receptor alpha (LXRalpha) and LXRbeta function a

32 s with many NRs, while L2 interacts with the liver X receptor alpha (LXRalpha) and the estrogen recep

33 Here we show the unexpected role of liver X receptor alpha (LXRalpha) as a direct transcript

34 Knockdown of liver X receptor alpha (LXRalpha) inhibited ABC transpor

35 activation of TLR-mediated innate immune and liver X receptor alpha (LXRalpha) signaling pathways.

36 nuclear hormone receptor for oxysterols, the liver X receptor alpha (LXRalpha), regulates cholesterol

37 level, and its expression is upregulated by liver X receptor alpha (LXRalpha).

38 -sensitive transcription factor SREBP-1c and liver X receptor alpha (LXRalpha).

39 enic transcription factors, most prominently liver x receptor alpha (LXRalpha).

40 ion of the anti-atherogenic nuclear receptor liver X receptor alpha (LXRalpha; Nr1h3) and its downstr

41 We have reported previously that liver X receptor-alpha (LXRalpha) can mediate a novel cA

42 mRNA and protein expression by up-regulating liver X receptor-alpha (LXRalpha) in macrophages.

43 have shown that the nuclear hormone receptor liver X receptor-alpha (LXRalpha) is a major transcripti

44 epatic DNL was due to coactivation by Vpr of liver X receptor-alpha (LXRalpha) with increased express

45 We determined that ATF6 induces liver X receptor-alpha (LXRalpha), an Mertk-inducing tra

46 r-activated receptor-alpha (PPAR-alpha), and liver X receptor-alpha (LXRalpha).

47 hese influences of HLP might be mediated via liver-X receptor alpha (LXRalpha)/ATP-binding cassette t

48 er for the nuclear hormone receptor known as liver X receptor alpha, (LXRalpha [NR1H3]), which is the

49 40, a co-repressor of feed-forward activator liver X receptor alpha, may mediate the negative regulat

50 Whereas liver X receptor-alpha-/- mice revealed no alterations i

51 ysterol treatment induced differentiation in liver X receptor-alpha-/- mice whereas in liver X recept

52 PP diet stimulated the hepatic expression of liver X receptor alpha mRNA.

53 osynthesis is provided by oxysterols through liver-X-receptor alpha (NR1H3), while feedback regulatio

54 317 induces dramatic up-regulation of p27 in liver X receptor alpha-overexpressing MDA-MB435S cells.

55 ased, as are key lipid metabolism regulators liver X receptor alpha, peroxisome proliferator-activate

56 BP) alpha, C/EBPbeta, C/EBPdelta, PPARgamma, liver X receptor alpha, sterol regulatory element-bindin

57 ic gluconeogenesis primarily by upregulating liver X receptor alpha through the natriuretic peptide p

58 Although liver X receptor alpha was induced, there was no detecta