ライフサイエンスコーパス: liver mitochondria

1 roblasts, HEK293 cells, and murine heart and liver mitochondria.

2 red to as mtMYH, has been purified from calf liver mitochondria.

3 n during 5-HT metabolism in isolated hamster liver mitochondria.

4 selectively localized in highly purified rat liver mitochondria.

5 sely affects the respiratory activity of rat liver mitochondria.

6 roximately 0.5 kD) in the matrix of isolated liver mitochondria.

7 ted to homogeneity from Percoll-purified rat liver mitochondria.

8 nd DA metabolism in isolated hamster and rat liver mitochondria.

9 and blocks mitochondrial pyruvate carrier in liver mitochondria.

10 d to ethanol, far in excess of that in adult liver mitochondria.

11 he permeability transition pore of heart and liver mitochondria.

12 e activity and the MMPT were measured in rat liver mitochondria.

13 s a key participant of ceramide formation in liver mitochondria.

14 findings, based upon their studies of mouse liver mitochondria.

15 e claim that a NOS isoform exists within rat liver mitochondria.

16 ansition (MPT) were assessed in isolated rat liver mitochondria.

17 g proteins derived from HeLa cells and mouse liver mitochondria.

18 pecific, because no decrease was observed in liver mitochondria.

19 ith mastoparan, an inducer of the MPT in rat liver mitochondria.

20 the metabolism of 10-HCO-THF by isolated rat liver mitochondria.

21 er membranes derived from swollen/shrunk rat liver mitochondria.

22 etic acid (DOPAC) in isolated hamster or rat liver mitochondria.

23 Isolated rat liver mitochondria (0.5 mg/ml) were incubated in multiwe

24 s, slightly enhanced respiration in isolated liver mitochondria (30.8% compared with control), lower

25 In isolated rat liver mitochondria, a cGMP analogue in the presence of a

26 dicate that increased levels of HNE in fetal liver mitochondria after maternal ethanol consumption re

27 y active state 3 respiration in AdN-depleted liver mitochondria, although further accumulation of AdN

28 nsition (MPT) pore opening in isolated mouse liver mitochondria, an effect that was prevented complet

29 e chose to readdress this question using rat liver mitochondria and employing a variety of assays tha

30 We also induce dANM for mouse liver mitochondria and envision that the separation mech

31 substrates of beta-oxidation in isolated rat liver mitochondria and hence are expected to yield 5,7-d

32 f tetraoleoyl-CL to tetralinoleoyl-CL in rat liver mitochondria and identified the intermediates lino

33 sm and lipid oxidation, is induced in fasted liver mitochondria and implicated in metabolic syndrome.

34 question by measuring K+ flux in intact rat liver mitochondria and in liposomes containing KATP chan

35 rt and oxidative phosphorylation in isolated liver mitochondria and in the cultured murine hepatoma c

36 brain nonsynaptosomal mitochondria and mouse liver mitochondria and mitoplast fractions derived from

37 ltransferase (GPAT) was determined using rat liver mitochondria and mutagenized recombinant rat GPAT

38 t fractionation, ultrapure, never frozen rat liver mitochondria and submitochondrial particles were o

39 atory showed that isolated, intact adult rat liver mitochondria are able to oxidize the 3-carbon of s

40 These studies confirm that liver mitochondria are early targets of injury during en

41 cute ethanol exposure in which HNE levels in liver mitochondria are strikingly increased.

42 (MT) localizes in the intermembrane space of liver mitochondria as well as in the cytosol and nucleus

43 r ion trap-mass spectrometry analyses of rat liver mitochondria as well as submitochondrial particles

44 GD3 directly induces the PT in isolated rat liver mitochondria at 30-100 microM in the presence of e

45 re we show that CBS proteins were present in liver mitochondria at a low level under normoxia conditi

46 idated using mouse cortical synaptosomes and liver mitochondria attached to XF24 V7 cell culture micr

47 In liver mitochondria, BAD resides in a functional holoenzy

48 Our aims were to determine if liver mitochondria become resistant to the MPT during ch

49 on in t-butyl hydroperoxide-stimulated fetal liver mitochondria, but not in adult mitochondria.

50 and an anti-mtGPAT immunoreactive protein in liver mitochondria, but not in microsomes.

51 he mtUDG activity did not change with age in liver mitochondria, but there was a small increase in ac

52 The permeability transition pore of rat liver mitochondria can be closed by chelating free Ca2+,

53 and extent were normal in isolated Mfn2(-/-) liver mitochondria, consistent with the finding that acu

54 s, the P/O ratios obtained with isolated rat liver mitochondria consistently exceed 2.5 with NAD-link

55 l-related decreases in COX activity found in liver mitochondria could be attributable to HNE adduct f

56 he overall activity of the CU in cardiac and liver mitochondria, even at the highest estimated values

57 Here we report that liver mitochondria exhibit ceramide formation from sphin

58 Percoll-purified rat liver mitochondria exhibited a negligible contamination

59 Immunoblot analysis of mouse liver mitochondria failed to detect AQP8 expression, wit

60 Respiratory control index values on rat liver mitochondria for this series suggested uncoupling

61 Isolated liver mitochondria from alcohol-treated mice had a great

62 uding analytical parameters, from a study of liver mitochondria from control and diabetic rats are pr

63 Additionally, liver mitochondria from ethanol-fed rats containing high

64 Liver mitochondria from homozygous mutant mice, with a c

65 Liver mitochondria from iPLA(2)gamma(-/-) mice were mark

66 s suggested the presence of a second GPAT in liver mitochondria from mtGPAT(-/-) mice.

67 Liver mitochondria from PY plus LPS or PY plus TNF-alpha

68 mitoKATP-mediated K+ flux in both heart and liver mitochondria from rat.

69 In this study we examined the properties of liver mitochondria from transgenic mice expressing HCV c

70 Liver mitochondria from transgenic mice expressing the H

71 y accelerated Ca(2+)-induced mPTP opening in liver mitochondria from wild-type mice.

72 dienoyl-CoA reductase (EC 1.3.1.34) from rat liver mitochondria has been investigated.

73 We also report that highly purified liver mitochondria have ceramidase, reverse ceramidase,

74 active proteins in wild type and mtGPAT(-/-) liver mitochondria have different isoelectric points.

75 In liver mitochondria, imeglimin redirects substrate flows

76 bited calcium-induced AIF release from mouse liver mitochondria, implicating the involvement of an en

77 y examines the effect of alcohol exposure on liver mitochondria in a rat model and explores the inter

78 responsible for the accumulation of AdNs in liver mitochondria in a strictly Ca(2+)-dependent way wi

79 mitoylcarnitine-supported respiration of rat liver mitochondria in concentration-dependent and time-d

80 Here, we show that liver mitochondria in fasting mice adapt to the demand o

81 ase in oxidative phosphorylation observed in liver mitochondria in response to glucagon and Ca(2+)-mo

82 yze changes in lysine acetylation from mouse liver mitochondria in the absence of SIRT3.

83 PCs and PSs in lipid extracts from isolated liver mitochondria in two different rat strains.

84 d that ribosomes stably bind to purified rat liver mitochondria in vitro.

85 inhibitor of Ca2+-stimulated respiration of liver mitochondria in vitro.

86 AdN content, state 3 respiration and CRC in liver mitochondria in wild type but not in SCaMC-3-KO mi

87 istent with this concept, H2O2 production by liver mitochondria increases from 5 minutes to 3 hours a

88 During fasting, NAD in liver mitochondria increases, thereby triggering SIRT5 d

89 e activity was also observed in isolated rat liver mitochondria incubated with alpha-TOS and tBOOH.

90 expressing HCV core protein, and from normal liver mitochondria incubated with recombinant core prote

91 Brain and liver mitochondria isolated by a discontinuous Percoll g

92 susceptibility to the calcium-induced MPT in liver mitochondria isolated from a knock-in HD mouse mod

93 In contrast, liver mitochondria isolated from iNOS-/- mice fed ethano

94 Using mouse liver mitochondria isolated from ogg1(-/-) mice, we show

95 antisera against various subfractions of rat liver mitochondria (mitoplast, inner membrane, intermemb

96 Mn-SOD expression and activity of Ad.SOD2 in liver mitochondria of infected animals was increased nea

97 This effect is also seen in liver mitochondria of RSV-fed animals (50 mg/kg/day).

98 e level of total glutathione was 30% less in liver mitochondria of the Sod2(-/+) mice.

99 r, the levels of ceramide were dissimilar in liver mitochondria of WT and NCDase KO mice.

100 SOD1 specifically in spinal cord, but not in liver, mitochondria of SOD1 mice and patients.

101 her is associated with the outer membrane of liver mitochondria (OM cyt b5).

102 inhibitor of the permeability transition in liver mitochondria, only protects against neuronal injur

103 lity transition or cytochrome c release from liver mitochondria or GCDC-induced mitochondrial depolar

104 Using rat liver mitochondria, our data demonstrate that calcium-me

105 However, liver mitochondria possess alternative anabolic pathways

106 ion (109% compared with control) in isolated liver mitochondria, probably due to increased levels of

107 dependent increases in oxidant production by liver mitochondria promote the induction of antioxidant

108 ificantly decreased respiratory rates in rat liver mitochondria relative to untreated controls, compl

109 r carnitine) as CPT I in skeletal muscle and liver mitochondria, respectively.

110 globin and nitrite to isolated rat heart and liver mitochondria resulted in the inhibition of respira

111 Protease treatment of rat liver mitochondria revealed that GPAT has a membrane-pro

112 ot affect the State 4Deltapsi of RBM and rat liver mitochondria (RLM).

113 tochondria in PC12 cells and of isolated rat liver mitochondria showed that hypoxia induced depolariz

114 In isolated mouse liver mitochondria, SR4 similarly increased oxygen consu

115 GST release) and NAPQI toxicity in isolated liver mitochondria (succinate dehydrogenase inactivation

116 Experiments on lysates from rat liver mitochondria suggest the ratio MB/cytochrome c is

117 Studies with isolated mouse liver mitochondria suggested that [Dmt1,dnsDap4]DALDA ta

118 el of the mPT in populations of isolated rat liver mitochondria that quantitatively describes Ca(2+)-

119 Rottlerin increased the QO2 of isolated rat liver mitochondria to a level similar to that produced w

120 tAPE, we purified the APE activity from beef liver mitochondria to near homogeneity, and showed that

121 were characterized by exposing isolated rat liver mitochondria to physiological and pathological rat

122 Liver mitochondria undergo dynamic alterations following

123 ake, even though ruthenium red-inhibited rat liver mitochondria undergo rapid pore opening under anal

124 on monoamine metabolism in isolated hamster liver mitochondria using 5-HT as the substrate.

125 Finally, Western blot analyses of rat liver mitochondria, using NOS (neuronal or endothelial)

126 We found that the GSH content of isolated liver mitochondria was diminished by >/=50% in GGT(-/-)

127 Similarly, peroxidase activity of murine liver mitochondria was high with FFA-OOH.

128 ed by the 2,4-dienoyl-CoA reductase from rat liver mitochondria was investigated.

129 might be linked, respiration of isolated rat liver mitochondria was measured after addition of Zn(2+)

130 se (CPS)-1, a protein primarily localized to liver mitochondria, was found to be present in high conc

131 atory control ratios (RCRs) of GGT(-/-) mice liver mitochondria were </=60% those of wild-type mice p

132 Intact and swelling bovine heart and rat liver mitochondria were examined with an excitation wave

133 nd, recombinant SCAD activity and antigen in liver mitochondria were found up to 7-fold of normal con

134 em mass spectrometry, respectively, when rat liver mitochondria were incubated with elaidoyl-CoA but

135 s end, changes in H(2)O(2) production by rat liver mitochondria were monitored at different rates of

136 Hepatocytes and liver mitochondria were obtained from bile duct-ligated

137 Rat liver mitochondria were purified by differential and Per

138 Extracts of isolated rat liver mitochondria were subjected to blue native polyacr

139 ate production was confirmed in isolated rat liver mitochondria where formate production from serine,

140 so be efficiently imported into isolated rat liver mitochondria, where it is processed to its native

141 idation (FAO) proteins were less abundant in liver mitochondria, whereas FAO protein content was indu

142 PHOS subunits were coordinately increased in liver mitochondria, whereas mitochondria of other tissue

143 ificant degradation of mtDNA in isolated rat liver mitochondria, whereas the same concentration of dy

144 We identified NEIL1 in liver mitochondria, which could account for the residual

145 Nnt inhibition in liver mitochondria, which do not require substrates to d

146 mounts of the ROS hydrogen peroxide, whereas liver mitochondria, which express a different Ant isofor

147 heir genomes and isolated a protein from rat liver mitochondria with 8-oxoguanine (8-oxodG) DNA glyco

148 Moreover, incubation of respiring rat liver mitochondria with [(14)C]cytidine diphosphate lead

149 Incubating mouse liver mitochondria with an HCV core (100 ng/mg) in vitro

150 such as tetraethylammonium and lysine by rat liver mitochondria with EC50 = 11-15 microM.

151 Incubation of intact liver mitochondria with physiological, micromolar concen