ライフサイエンスコーパス: load

1 m underlying late-onset Alzheimer's disease (LOAD).

2 Ag testing and had an undetectable HBV viral load.

3 ors of patient outcome, independent of viral load.

4 es more when they walk with (versus without) load.

5 sometric contraction to shortening under low load.

6 al and no effects of pesticides on infection load.

7 d with a mild elevation in fibrillar amyloid load.

8 cies respond, possibly due to low mutational load.

9 ockouts and challenged them with an oral fat load.

10 impairment, mortality, and spinal cord viral load.

11 calendar year, cohort, CD4 count, and viral load.

12 ime and correlated with the individual viral load.

13 RT or presenting with a high tissue parasite load.

14 ere strongly associated with the overall POP load.

15 ted for <1.5% of the incoming total nitrogen load.

16 ory symptoms, lung function, and nasal viral load.

17 hagocytosis, resulting in elevated bacterial load.

18 h in turn may promote crack initiation under load.

19 rives CD4 decline independently of the viral load.

20 erns linked to increased reward or cognitive load.

21 n population fitness known as the mutational load.

22 l among those with higher and lower chloride loads.

23 g TWA concentrations to derive flow-weighted loads.

24 tiretroviral therapy with undetectable viral loads.

25 get of rapamycin complex 1 (mTORC1) when GTP loaded.

26 the cells encode magnitude and frequency of loading.

27 m that emerges in these architectures during loading.

28 rproduction uncouples short G1 from fast MCM loading.

29 ir layers allows high levels of nanoparticle loading.

30 nd PH after at least 12 months of functional loading.

31 ion within the martian mantle due to crustal loading.

32 ith patients admitted for dofetilide initial loading.

33 s with CMV pneumonia had higher median viral loads (3.9 log10 IU/mL; interquartile range [IQR], 2.6-6

34 eline, 9 patients had a detectable HBV viral load, 7 had positive results on hepatitis B surface anti

35 bon +5.33 x 10(5) particles/ml higher carbon load (95% confidence interval, 1.56 x 10(5) to 9.10 x 10

36 est transfemoral amputees could benefit from load-adaptive powered knee controllers, and controller a

37 Evidence is summarized how mismatched eplet loads affect antibody responses and transplant outcomes.

38 Although we found higher viral loads among pneumonia cases than controls for some virus

39 stfeeding; ART treatments can suppress viral load and are key to preventing transmission to the child

40 al without considering the role of HCV viral load and genotype.

41 mune-compromised flies with higher bacterial load and gut cell death.

42 antitative PCR was used to compare bacterial load and Illumina MiSeq sequencing of the V1-V3 regions

43 vels, ASCs and HAI titers with reduced viral load and inflammatory responses in the cVLP group.

44 e that responded to both types of visuomotor load and its activity was associated with larger pupilla

45 significant increases in average daily peak load and overall electricity consumption in southern and

46 Although mutation load and PD-L1 immune cell (IC) staining have been assoc

47 Interestingly, viral load and tissue viremia, but not intermittent viral blip

48 emonstrated quantitative estimation of tumor load and tissue-of-origin mapping in the circulating cel

49 abling the system to be tuned to the desired load and to clear the working memory of currently held i

50 ent platform CoGe, assembled genomes are pre-loaded and available for analysis, as well as letting re

51 athode is presented here that enables sulfur loading and content as high as 46 mg cm(-2) and 70 wt% w

52 The reactions operated with low catalyst loading and generally occurre within 15 min at room temp

53 e distribution of positive instances in both loading and leakage models was similar in the two databa

54 s; however, they often feature high catalyst loading and low turnover numbers relative to non-oxidati

55 tration, ratio of t-butanol to slurry, solid loading and pH.

56 and adaptable geometries for the controlled loading and release of medicines is presented.

57 bules of mice subjected to dietary potassium loading and restriction, KS-WNK1 knockout mice were defi

58 ry phosphorylation of RhoA, reduced RhoA GTP-loading and reversal of myosin light chain phosphorylati

59 d and characterized two distinct Cdc8 cables loading and spreading cooperatively on individual actin

60 g liposomes with (52)Mn, through both remote-loading and surface labeling.

61 such porous structures as a function of CNT loading and the method used for their surface functional

62 re we provide a global estimate of microbial loads and air-sea exchanges over the tropical and subtro

63 nucleoside analogue entecavir reduced viral loads and decreased liver inflammation.

64 inical signs for 2 years, despite high viral loads and the accumulation of large intracellular inclus

65 ants with clinical signs had higher parasite loads and were significantly more likely to be detected

66 g) testing and had an undetectable HBV viral load, and 3 had negative results on HBsAg testing and ha

67 iable analysis, age, historical plasma viral load, and ART regimen changes prior to interruption were

68 Viral serology, viral load, and liver biochemistry were performed at regular i

69 post-TAVR blood pressure, systemic arterial load, and mortality.

70 trate differences in survival and mutational load as well as stromal and immune cell composition.

71 These were tested with the Xpert HCV Viral Load assay, and results were compared to quantification

72 Heritability and polygenic load associated with Tourette syndrome, OCD, and ADHD we

73 st adjuvanted antigen 85B (Ag85B)/peptide 25-loaded BCG-mimicking nanoparticle formulation was evalua

74 these structures hold great promise as high load bearing and impact-resistant materials due to a uni

75 wood fibers, and added silicates yielding a load-bearing and low-subsidence composite.

76 tment and that this is required for improved load-bearing capacity and silencing of the spindle assem

77 l surfaces and to tether microfibrils into a load-bearing network, thereby playing a central role in

78 t was performed at baseline and after saline load before and after pericardial resection in normal ca

79 cleosomes or roadblocks resulted in helicase loading being dependent on an additional origin sequence

80 ct comparisons of erosion during pulsed heat loading between PFC candidate materials will ensure that

81 lated with 5-30 folds within the equiaxially loaded biphasic scaffolds compared to unstrained samples

82 hose on treatment to have a suppressed viral load by 2020, with each individual target reaching 95% b

83 ventricle adapts to the increasing vascular load by enhancing contractility ("coupling") to maintain

84 ment source; therefore, we hypothesized that loading C3 from plasma was a route of establishing intra

85 s on the heart, and over time, these chronic loads can cause heart failure.

86 The encapsulation efficiency (82.8%), loading capacity (35.38%) and FT-IR spectroscopy demonst

87 with uniform size distribution, large oxygen loading capacity, high LLL12 encapsulation efficiency, w

88 e in catalytic efficiency compared to the Pt loaded carbon sphere catalyst in aqueous hydrogenation r

89 timized in batch mode, by evaluating protein loading, caseinolytic activity and the coagulation prope

90 In the first stage of clamp loading, clamp loaders bind and stabilize clamps in an o

91 rapidly but transiently to the MHC class II loading compartment, as does Ag conjugated to H4B4.

92 In the stereodetermining step the resulting loaded complex evolves via an inner-sphere mechanism int

93 ovides a binding site for the Scc2/4 cohesin loading complex, thereby directing cohesin loading to ce

94 The loading concentration had no influence on short-term flu

95 dent SEDFIT-MSTAR analysis across a range of loading concentrations.

96 We show that, for the inbreeding loads considered, CM leads to unacceptably high extincti

97 t for the virus to evolve intermediate viral loads consistent with maximising transmission, as is obs

98 itive to changes in ventricular geometry and loading, current therapy is mainly focused on resting co

99 mouse model, we demonstrate that doxorubicin-loaded (D)CDX-RBCNPs have superior therapeutic efficacy

100 nt of the cholesterol measured by this paper-loaded DART mass spectrometry (pDART-MS) is statisticall

101 ure confounders and normalizing the residual load data for each country, we estimate a common dose-re

102 Postpartum hepatitis C viral (HCV) load decline followed by spontaneous clearance has been

103 Attachment lifetimes under load decrease monotonically with force, indicating slip-

104 o enhanced protection with reduced bacterial load, decreased chemokine expression, and reduced inflam

105 at inhibited ORC-DNA binding showed helicase loading defects.

106 ic skin sectioning, with 74.2+/-9.18% of VD3 loading delivered intradermally.

107 , saturated fat, dietary fiber, and glycemic load derived from self-report of dietary intake and circ

108 Drug loading did not affect the radiopacity and there was a d

109 ) around immediately loaded (IL) and delayed loaded (DL) implants in smokers and non-smokers.

110 Results under loading dose and maintenance therapy regimens were nearl

111 zumab emtansine 3.6 mg/kg; pertuzumab 840 mg loading dose, 420 mg maintenance doses) or docetaxel, ca

112 ime curve 6 mg/mL x min; trastuzumab 8 mg/kg loading dose, 6 mg/kg maintenance doses) plus pertuzumab

113 f custirsen 640 mg intravenously after three loading doses of 640 mg.

114 a hepatic arterial pump or port, irinotecan-loaded drug-eluting beads, and radioembolization using (

115 mistry model, we find that increased aerosol loading due to anthropogenic activities in China substan

116 on whose expression is associated with viral load during experimental rhinovirus infection of asthmat

117 that this resulted from increased cognitive load during language switches.

118 Abnormal pulsatile aortic loading during exercise occurs in HFpEF independent of h

119 nteraction sites for proteins, enabling high loading efficiency and enhanced stability.

120 sion, re-assembled casein micelles with high loading efficiency show promise for improving vitamin D

121 2i, 1) the HT depot surface gained high MK2i-loading efficiency through charge-charge interaction, an

122 along the food chain to reduce Campylobacter load, especially on chicken meat.

123 le range and the root-mean-squared error) of load estimates a modeling exercise showed that passive s

124 o clear trends were evident in the ratios of load estimates from passive samplers relative to grab sa

125 of character evolution describing how viral load evolves on the phylogeny of whole-genome viral sequ

126 hypothesized that transfusion of leukocytes loaded ex vivo with the lipophilic antifungal posaconazo

127 complement to the chemistry surrounding the loading, extension, and offloading of assembly lines tha

128 Here we show that deletion of the cohesin-loading factor Nipbl in mouse liver leads to a marked re

129 uel during migration, but the effect of fuel loads (fat) acquired at stopover sites on the subsequent

130 Here, we use iron oxide-loaded ferritin proteins to create a stable and highly e

131 t is widely applicable and enables high drug loading for improved ADC potency.

132 which we use to compute national electricity loads for temperatures that lie outside each country's c

133 Only under large loading forces can the motor head release ATP at a fast

134 imilar (instead of elevated) NO3(-) leachate load from soybean fields (no N fertilizer applied).

135 ompression and tension) and nano-indentation loading geometries, our findings demonstrate that the fo

136 only one eliciting low GI of 50 and glycemic load (GL) of 13 while the rest exhibited GI ranging from

137 2) when sweetness is proportional to caloric load, greater metabolic responses are observed.

138 Late systolic load has been shown to cause diastolic dysfunction in an

139 experimental conditions and dealt only with loading, here we reduced the scope to the molecular char

140 t % of carboxymethyl cellulose with an areal loading higher than 3 mg cm(-2) achieve an overall speci

141 The drug-loaded hollow nanoparticles were effective at delivering

142 A similar risk was seen with high betaPV loads (HR 1.8, 95% confidence interval 1.2-2.8).

143 d crestal bone loss (CBL) around immediately loaded (IL) and delayed loaded (DL) implants in smokers

144 showed significant association with genetic load in a pan-cancer analysis.

145 Pneumococcal load in blood was not associated with respiratory tract

146 re was no significant difference in mutation load in cancer-associated genes between regions that wer

147 We hypothesized that an elevated mutation load in combination with T cell clonal dominance among i

148 gh expression of IL1beta and high D. nodosus load in footrot samples.

149 Defining mutation load in individual pancreatic cancers and the optimal as

150 analysis to compare NO3(-) concentration and load in NT and CT systems via two major transport pathwa

151 not enhance their excitability and oxidative load in response to chronic mutant alpha-synuclein overe

152 se critical bone cells respond to mechanical load in vivo, as well as provide a technique to determin

153 Here, we report that optimization of caloric loading in B6 mice subject to HFS, characterized by incr

154 tagonist leg muscle coactivation during limb loading in early stance, and (2) changes in the magnitud

155 methodology to optimize fat-soluble vitamin loading in re-assembled casein micelles, and to evaluate

156 nnual timescales coincides with hydrological loading in the upper Mississippi embayment.

157 tosis and increased nasopharyngeal bacterial loads in ccl3(-/-) mice.

158 ar pH (pHi ) recovery (decrease) from alkali loads in neurons and, surprisingly, adjacent astrocytes.

159 vironment and respond to changing mechanical loads in order to maintain cartilage homeostasis.

160 nerve activity produces large and rapid acid loads in presynaptic terminals.

161 Patients with higher peripheral blood viral loads in primary infection and greater changes in viral

162 d develop comparable pathology and bacterial loads in the organs, demonstrating that the plasmid does

163 periences of societal inequality (allostatic load) increase the complexity of studying breast cancer

164 Further, the equiaxial load induced region-specific differentiation of ASCs wit

165 ype mice was found to significantly increase load-induced bone formation and Wnt/beta-catenin activit

166 nolic acid (AA), in ameliorating hemodynamic load-induced cardiac fibrosis and identified its intrace

167 Load-induced relative changes were determined and analyz

168 ding to the release and decomposition of the loaded initiator to generate free radicals.

169 The extracted solution containing DOC was loaded into the injection valve of the continuous flow m

170 efficient encapsulation of drugs via remote loading into membrane vesicles derived from red blood ce

171 Remote drug loading into nano-liposomes is in most cases the best me

172 Wnt5a-Rac/Rho-mediated decrease in parasite load is associated with an increase in F- actin assembly

173 in tissue deformation induced by head impact loading is greatest in sulcal locations, where pathology

174 Mechanical loading is necessary for the development and maintenance

175 onfigurable Huygens' metasurface realized by loading it with controllable active elements.

176 mation can characterize a tumor's neoantigen load, its cadre of infiltrating immune cell types, the T

177 Ru-loaded LaScSi shows outstanding catalytic activity for a

178 do not become infected, although high tumour loads lead to high mortality.

179 es, our findings demonstrate that the former loading leads to size-independent mechanical properties

180 inical presentation: intrarenal polyomavirus load levels and Banff interstitial fibrosis ci scores.

181 itumor and anti-metastasis efficacy of CREKA-loaded liposome was more obvious than that of free Dox o

182 used T2-weighted scans to quantify WM lesion loads (LLs) and diffusion-weighted images to assess thei

183 ave cirrhosis, and have a pretreatment viral load <6,000,000 IU/mL.

184 The respective Li(+)-, Na(+)-, and Mg(2+)-loaded materials exhibit high ionic conductivity values

185 examined time to LTC (defined as first viral load measurement after release) and viral suppression at

186 ides an efficient and reproducible method of loading micelles with hydrophobic drugs.

187 Results from experiments using AGO2-loaded miRNAs in duplex with target mRNAs indicate that

188 When loading MK2i, 1) the HT depot surface gained high MK2i-l

189 erstanding of how organic carbon and nitrite loads modulate N2O accumulation in denitrification, whic

190 Effective viral load monitoring and point-of-care resistance tests could

191 Landon Myer and colleagues discuss viral load monitoring for pregnant HIV-positive women and thos

192 2.8-16.8 months) in this setting where viral load monitoring was available.

193 perator input to enhance the access to viral load monitoring.

194 -rTMS), all including an N-back task (3 task loads: N1, N2, N3; control condition: N0) inside the MR

195 osome that enable therapeutically viable API-loaded nano-liposomes, referred to as nano-drugs.

196 Rapid diffusion of these DNA-loaded nanocomplexes observed in fresh tissues ex vivo d

197 peutic implications of these natural, remote-loaded nanoformulations are studied both in vitro and in

198 anding of the intracellular behavior of drug-loaded nanoparticles, and provides insights for the desi

199 Our hybrid dielectric-loaded nanoridge plasmonic platform may serve as a funda

200 The accumulation of drug-loaded NPs targeted with 3F8 versus with control antibod

201 cyte death resulted in the highest bacterial load observed starting from early adulthood.

202 elite controllers (ie, persons with a viral load of </=40 copies/mL) and noncontrollers, antibody pa

203 ment, the proportion who died or had a viral load of 400 copies/mL or higher at 12 months post-ART in

204 st that such practices could help reduce the load of antibiotic-resistance genes in the environment.

205 h recombinant Wnt5a caused a decrease in the load of antimony-sensitive and -resistant parasites, thu

206 We monitored the viral load of MJNV RNA in various tissues of shrews, which wou

207 our approach, we demonstrate that a greater load of Neanderthal-derived genetic variants (higher "Ne

208 Significantly, increased cellular load of R-loops and DSBs, which are normalized on RNaseH

209 for some viruses, the utility in using viral load of URT specimens to define viral pneumonia was equi

210 nt of fill volume variation in the effective load of your reactions.

211 ame as those obtained with a Pt cathode at a loading of 0.1 milligram of Pt per centimeter squared.

212 Further, we report on successful co-loading of 17-AAG (Hsp90) and rapamycin (mTOR) (g-EAR).

213 formance metrics are attributed to the large loading of active materials, minimization of inactive ma

214 en too low ethanol yields at the high-solids loading of biomass needed during fermentation to realize

215 The device allows the simultaneous loading of cells into 16 separate chambers, each contain

216 anding CD/linalool-IC-NFs facilitate maximum loading of linalool up to 12% (w/w).

217 osely related field of nanoparticle membrane-loading of liposomes and polymersomes.

218 ystems have been severely affected by excess loading of macronutrients (e.g., nitrogen and phosphorus

219 results indicate that the increased ribosome loading of modified mRNAs renders them more permissive f

220 Maternal loading of piRNAs in oocytes is further required for the

221 for antibiotic susceptibility testing, from loading of sample to diagnostic readout, is less than 30

222 istic gene induction is achieved by assisted loading of STAT3 on chromatin by NF-kappaB.

223 We combined loading of the lipophilic dye FM1-43 with photoconversio

224 We demonstrate the loading of two model drugs: the chemotherapeutic doxorub

225 sed to provide dynamic population normalized loads of illicit drugs and pharmaceuticals during a know

226 of 65 in the bictegravir group had HIV-1 RNA loads of less than 50 copies per mL compared with 31 (93

227 retroviral therapy, and 29 (36.7%) had viral loads of more than 50 000 copies per mL.

228 onditions and the human originated microbial loads of these products were determined.

229 l auristatin E (MMAE) significantly increase loading on a per-vehicle basis as compared to antibody-d

230 e procedures often place pressure and volume loads on the heart, and over time, these chronic loads c

231 lyze effects of this loss and other cochlear loads on TM traveling waves.

232 t chains and produces antigenic peptides for loading onto major histocompatibility complex (MHC) clas

233 No such difference in bacterial load or lesion size was detected in galectin-3(-/-) mice

234 stimulated using BK virus peptide libraries loaded or not on monocytes-derived dendritic cells.

235 configurations coupled with a flexibility in loading order, resulting in many possible junctional out

236 of misfolded/unfolded proteins when protein load overwhelms the ER folding capacity, which activates

237 oni-corrected P value [BP] = 1.3 x 10-3) and LOAD (P = 6.22 x 10-6; BP = 4.1 x 10-3).

238 bly adorned with Toll-like receptor-9 ligand-loaded particles using streptavidin-biotin cross-linking

239 gularis populations as mean stigmatic pollen load per population.

240 tes hybrid plasmon polariton with dielectric-loaded plasmonic waveguiding.

241 els, we predict that (1) relative to passive loading, polymerization of Suc in the phloem, even in th

242 7 from included pharmacophores (or from drug loaded porous particles).

243 rrelation coefficients, and better canonical loading profiles than the competing methods.

244 This process is featured with pre-loading proteins into polysaccharide fine particles via

245 DENV infections were detected and viral load quantitated by real-time reverse transcription-poly

246 cally dissociating the Fn.peptide complex at loading rates relevant to the cardiovascular system, var

247 tion in digesters, permitting higher organic loading rates.

248 o substantial interannual variability, a 25% load reduction is required before there is 95% certainty

249 At zero PO4(3-) loading, reductive dissolution appears to be constrained

250 ed to control electrical properties and drug-loading/release characteristics.

251 The high cognitive load required to navigate such a workflow is detrimental

252 or HEV genotypes (code 8578/13) showed viral load results falling within the result ranges generated

253 C correlated directly with both plasma viral load (Rho = 0.3531; P = 0.0218) and the proviral copy nu

254 ate less brain beta-amyloid and have a lower LOAD risk.

255 ive of diffuse RV fibrosis, for which volume loading seems to be a risk factor.

256 , for which transport distances are largest, loading seems, counterintuitively, to occur by means of

257 Given its negative effect, genetic load should make tumors more sensitive to anticancer dru

258 carried out by two conformers that can both load simultaneously on the origin of transfer DNA.

259 he timescale of 100-200 ns before the proton-loading site is protonated.

260 behaviour and fatigue life under a realistic load spectrum.

261 d, decreased peak ICa-L offsets increased SR load such that Ca(2+) release from the SR was maintained

262 oma observed a reduction in cumulative tumor load, suggesting most benefit to be gained by early conv

263 d on responses to HIV-1-infected and peptide-loaded target cells.

264 g data of human immunodeficiency virus (HIV) load testing are pivotal to limiting the threat of HIV d

265 IMD(0), GES, water load testing, and symptoms were then compared in 177 pat

266 ients, which will be vital in ensuring viral load tests are appropriately used to improve the quality

267 d new genomic measures of damaging passenger load that can accurately predict the fitness costs of pa

268 as is observed, and not the very high viral loads that previous models have predicted, an effect tha

269 al sample; (iii) serially diluting cells and loading them into the ichip; (iv) returning the ichip to

270 n loading complex, thereby directing cohesin loading to centromeres.

271 apable of delivering well-defined mechanical loads to metatarsal bones of living mice while simultane

272 enerally, RF caused an increase of microbial loads to values >/=6.0logCFU/mL after 7days of storage.

273 eport a microfluidic platform lab-on-a-disc (LOAD) to provide a sample-to-answer solution.

274 Iron-loaded transferrin binds to transferrin receptor 1 on th

275 the median time to undetectable plasma viral load (VL) can be reduced from approximately 5 d to appro

276 Although WHO recommends viral load (VL) monitoring for those on antiretroviral therapy

277 We compared the rectal HCV viral load (VL) with paired blood HCV VL.

278 g among women with undetectable plasma viral load (VL).

279 virus and hepatitis delta virus (HDV) viral loads (VL) during tenofovir-containing antiretroviral th

280 count documentation, whereas higher patient load was associated with decreased attrition.

281 Load was higher in MCPP cases than controls (median, 4.0

282 The urinary black carbon load was positively associated with medium-term to chron

283 HHV-6 shedding rate and viral load were similar between children with primary or chron

284 Allergen loads were on average higher in DCC than in homes.

285 uconeogenic module operates through assisted loading, whereby GR doubles the number of sites occupied

286 quantify the heritability of set-point viral load, which is the fraction of variation in this phenoty

287 rsity explains 29% of the variation in viral load while host factors explain 8.4%.

288 sm were abolished by reducing the neutrophil load with in vivo administration of an anti-Ly6G antibod

289 d NTSLs containing doxorubicin (Dox) were co-loaded with a nanobubble contrast agent (perfluoropentan

290 ocessing and PCR amplification functions was loaded with all reagents needed for sample processing an

291 In the case of cages loaded with C60 or C70 fullerenes, ultrafast host-to-gue

292 oatings of polyethylene glycol (PEG) and are loaded with cisplatin (CDDP) could be delivered across b

293 The results showed that nanoparticles loaded with hydroxycinnamic acids (HA-NCs) have diameter

294 This study demonstrated that scaffolds loaded with PEI-(pBMP-2+pFGF-2) could be an effective wa

295 fic for a foreign MHC class II molecule type loaded with peptides from leukocytes from the graft.

296 cell-targetable, icosahedral DNA-nanocapsule loaded with photoresponsive polymers, we show cytosolic

297 caffolds were prepared via freeze drying and loaded with plasmid DNA encoding perlecan domain I and V

298 ized with long-lived induced-dendritic cells loaded with the pp65 viral antigen (iDCpp65) exhibited a

299 be run on a gram scale with reduced catalyst loading without impacting the efficiency.

300 blood sample had high cell-associated viral loads without a marked CD8 lymphocytosis or NK cell dist