ライフサイエンスコーパス: lobuloalveolar

1 irus or only Env transgenes showed increased lobuloalveolar budding.

2 ridine labeling in the terminal end buds and lobuloalveolar buds.

3 or RANK control the proliferation of mammary lobuloalveolar cells during pregnancy through inhibitor

4 ression of IRF6 in quiescent, differentiated lobuloalveolar cells of the lactating mammary gland comp

5 ice should show premature development of the lobuloalveolar compartment because of hyperactivation of

6 ull mice show accelerated development of the lobuloalveolar compartment, premature milk production, a

7 t Delta N 89 beta-catenin induces precocious lobuloalveolar development and differentiation in the ma

8 in virgin transgenic females, Skp2B induces lobuloalveolar development and differentiation of the ma

9 eta-/- mammary glands displayed only limited lobuloalveolar development and ductal side branching.

10 y curtailed in transgenic virgin mice, while lobuloalveolar development and functional differentiatio

11 nase-dead Pak1 transgene revealed incomplete lobuloalveolar development and impaired functional diffe

12 r2 constitutive expression drives precocious lobuloalveolar development and increased milk protein ex

13 regnancy-associated ductal sidebranching and lobuloalveolar development are markedly reduced due to d

14 (TGF-beta) is thought to regulate ductal and lobuloalveolar development as well as involution in the

15 model, we show that Agr2 facilitates normal lobuloalveolar development by regulating mammary epithel

16 the mammary glands of mice leads to impaired lobuloalveolar development due to decreased epithelial c

17 in D1 is a major downstream target of PRL in lobuloalveolar development during pregnancy and is ampli

18 ctal elongation in virgin animals, increased lobuloalveolar development during pregnancy, and delayed

19 in conjunction with local factors, leads to lobuloalveolar development during pregnancy.

20 irectly on the mammary epithelium to produce lobuloalveolar development during pregnancy.

21 the terminal end buds, as well as decreased lobuloalveolar development in adult females, and fewer m

22 regulates epithelial cell proliferation and lobuloalveolar development in the mammary gland.

23 the actions of E2 on cell proliferation and lobuloalveolar development in the mammary glands of fema

24 steroids, which stimulate proliferation and lobuloalveolar development of mammary epithelial cells,

25 verexpression of cyclin D2 may block mammary lobuloalveolar development through inhibition of cyclin

26 Lobuloalveolar development was delayed in response to pr

27 Lobuloalveolar development was not affected in glands th

28 alpha, is required for ductal morphogenesis, lobuloalveolar development, and functional differentiati

29 igment cell localization, precocious mammary lobuloalveolar development, and the appearance of mammar

30 D1 is a critical molecule in normal mammary lobuloalveolar development, these data suggest that over

31 esults in a highly specific defect in murine lobuloalveolar development.

32 one of the effector molecules essential for lobuloalveolar development.

33 the synthesis of milk despite the absence of lobuloalveolar development.

34 during pregnancy, and fail to undergo normal lobuloalveolar development.

35 g and the formation of alveolar buds, but no lobuloalveolar development.

36 rgin Cox-2 transgenic mice showed precocious lobuloalveolar differentiation and enhanced expression o

37 of Hif1a in the mouse mammary gland impairs lobuloalveolar differentiation during lactation.

38 ient epithelial cells fail to undergo normal lobuloalveolar differentiation during pregnancy.

39 n vivo and retained the potential to undergo lobuloalveolar differentiation in response to hormones o

40 ration, decreased ductal branching, impaired lobuloalveolar differentiation, and inability to lactate

41 for cyclin D1 induction and proliferation of lobuloalveolar epithelial cells.

42 hat different stages of ductal branching and lobuloalveolar formation are regulated by distinct sets

43 condary branching, ductal side-branching and lobuloalveolar formation.

44 Consistently, pregnancy induced extensive lobuloalveolar growth in the absence of cyclin D1.

45 on by s80(Cyt1) occurred simultaneously with lobuloalveolar growth that was unimpeded by s80(Cyt1), s

46 asia associated with apocrine metaplasia and lobuloalveolar hyperdevelopment during lactation.

47 ation of S phase fraction and development of lobuloalveolar hyperplasia.

48 The severity of lobuloalveolar impairment ranged from lobular hypoplasia

49 mammary gland resulted in the development of lobuloalveolar-like structure, which mimics the gland fr

50 However, mammary lobuloalveolar outgrowth during pregnancy was curtailed,

51 sponse to estrogen treatment and the mammary lobuloalveolar proliferation stimulated by estrogen plus

52 While there was no lobuloalveolar structure in control virgin mice, express

53 y during sexual maturation, but fail to form lobuloalveolar structures during pregnancy because of de

54 rease in ductal branching, smaller and fewer lobuloalveolar structures, and a decrease in luminal sec

55 ulted in a loss of ductal side-branching and lobuloalveolar structures, ductal dilation, and decrease