ライフサイエンスコーパス: local

1 or antagonistic drug characteristics and on local 5-HT1B receptor density.

2 Local 5-HT2CR knockdown in the BLA with stereotaxic inje

3 ndidates for potentially curative therapies (local ablation, resection, or transplantation).

4 nclear as the underlying architecture of the local actin network is often unknown.

5 Our study suggests that additionally to its local actions in the AD brain, TNF-alpha can also indire

6 diameters from wound edges is reminiscent of local activation of Toll in early embryonic ventral hypo

7 ural hybridization, which can be involved in local adaptation and in speciation processes, has been l

8 Genetic association studies of local adaptation combine data over populations.

9 may contain functional variants involved in local adaptation or reproductive isolation and may there

10 all, our results indicated a lack of thermal local adaptation, but a presence of plasticity in popula

11 erns of population structure consistent with local adaptation.

12 These data support the thesis that local adenosine generated by cells at the injury site is

13 s in brain parenchyma away from the point of local administration.

14 se (used in phase 3 trials), the most common local adverse events versus placebo within the first 14

15 ow cellular contact guidance is built on the local alignment of adhesions and individual protrusions.

16 challenges to antibiotics [40/44 (91%]) and local anaesthetics [41/44 (93%)].

17 In pursuance of efficient tools for the local analysis and characterization of novel photoelectr

18 s of irradiation of the interrogated sample, local analysis of semiconductor materials for light-indu

19 Inferring local ancestry in individuals of mixed ancestry has many

20 stimated local European ancestry (LEA) using Local Ancestry inference in adMixed Populations using Li

21 at LAIT provides convenience to run multiple local ancestry inference software.

22 Both local and global reactivity descriptors were used to stu

23 For stage 3, epidemic potential, we combined local and international scale connectivity assessments w

24 infections, including the implementation of local and national laboratory data-based surveillance sy

25 nd non-workday periods, the effectiveness of local and regional air pollution control policies and co

26 tion patterns and quality are analyzed among local and regional organizations working in hydrological

27 ces and species richness of poikilotherms at local and regional scales.

28 al ischemia followed by reperfusion leads to local and remote organ injury attributed to inflammatory

29 uble-strand breaks (DSB), apoptosis, and the local and systemic immune responses.

30 released implant-associated materials have a local and/or systemic impact on the peri-implant soft an

31 nderwent treatment at low-volume facilities (Local) and patients in the top quartile of travel distan

32 injection of 25 x 10 cells per segment under local anesthesia.

33 rated the deactivation of NsVBa, whereas the local anesthetic drug lidocaine was shown to antagonize

34 Here, we find that the local angiotensin II predominantly exists in the hypoxic

35 e initiation of the combs requires global or local anomalous dispersion which leads to many limitatio

36 ginal application as an approach to initiate local antigen-specific immunity, enhance previously exis

37 Increased IL-1beta boosts local antimicrobial peptides to facilitate microbiota re

38 and efficient biomonitoring tool to protect local aquatic ecosystems.

39 s transcription by attenuating the effect of local arginine methylation.

40 In addition to systemic inflammation, local arterial inflammation, driven by monocyte-derived

41 ls, nanostructures are often organized using local assembly rules that produce long-range order.

42 iving in England, with matching postcode and local authority data, to complete self-report surveys be

43 nocyte-like cells in the cochlea can mediate local autoinflammation via activation of the NLRP3 infla

44 d the extent of these effects are related to local availability of CB1 receptors.

45 yria and Saudi Arabia) and compare them with local bacterial communities sampled on clear days, all c

46 ring by mechanisms that are thought to tip a local balance of competing physical forces; cell-to-cell

47 a time-reversal-invariant surface state in a local bandgap in the (110)-projected bulk band structure

48 P responses, a disruption that resulted from local blockade of alpha7-nicotinic acetylcholine recepto

49 s involving neuronal-astrocytic signaling to local blood vessels to a multidimensional one in which m

50 ent of systemic inflammation, in addition to local brain inflammation, in Alzheimer's disease (AD) pr

51 type in mice by regulating blood-derived and local brain inflammatory cell populations involved in be

52 atric brain metabolism are uncommon, because local brain metabolism evolves significantly with age th

53 tivity in both pathways showed predominantly local but also some long-range correlations.

54 e materials, where tiling units arrange with local but no long-range order, remains challenging.

55 Local calcium upstroke was delayed (23.9+/-4.9 versus 10

56 rature-sensitive liposomes can reliably cure local cancer in mouse models.

57 Cities Initiative (CRSCI) that aims to build local capacity to assess and respond to the health impac

58 drives bacterial cell division by directing local cell wall synthesis.

59 tested by formalizing an index that measures local changes in climate using station data and comparin

60 nvironment complexity measure, CA, to assess local changes in complexity during synthetic transformat

61 e, unveiling the quantum phase transition of local character.

62 While annealing improves local chemical and electronic uniformity resulting in hi

63 ated domains (TADs), defined by preferential local chromatin interactions, and chromosome compartment

64 synaptic input, its precise relationship to local circuit architecture remains unclear.

65 These results imply that local circuitry is not a major contributor to gamma osci

66 rom large numbers of neurons across multiple local circuits and, importantly, allow stable tracking o

67 We have identified the local circuits of a population of cells in V1 layer (L)4

68 y elevated in NP, and there was evidence for local class switch recombination in NP.

69 , cleared or otherwise altered in structure, local climates and microclimates change.

70 wo coevolving costly traits: cooperative and local cohesive tendencies.

71 he landscape, with unknown repercussions for local communities and biodiversity conservation.

72 ive rise to spatial and temporal patterns in local community structure.

73 g avoidance or as a response to more intense local competition among kin.

74 he power and flexibility to be resident on a local computer or serve as a web-based environment, enab

75 tron beam illumination greatly increases the local concentration of free radicals, thereby strongly i

76 le can be protected from degradation, higher local concentrations and targeted delivery to the site o

77 ns may typically experience when adapting to local conditions.

78 rstood, modifications to cytosine affect the local conformational dynamics of a DNA duplex in a confi

79 e, DeltaG, of 6 kcal.mol(-1) between the two local conformations around a single bond.

80 challenge, in conjunction with remodeling of local connectivity.

81 ound 31 AIT-GLs (15 post-2010), ranging from local consensus reports to international position papers

82 and show that it proceeds in three stages: a local constriction ("waist formation"), pulsation-which

83 ollowing surgery with the goal of maximizing local control and increasing overall survival.

84 r non-MALT lymphomas (988 patients) reported local control rates to be 93.1%; 5-year and 10-year dise

85 cold air to East Asia and thus causes severe local cooling.

86 ces in intrinsic corticospinal excitability, local cortical GABA levels, and reaction time (RT) in a

87 nt density distribution, but they induce the local current crowding around the voids: this local curr

88 ocal current crowding around the voids: this local current crowding enhances the lateral void growth

89 using donor and recipient factors, based on local data sets, will be more beneficial in the Australi

90 nputs or coactivation of a smaller subset of local dendrodendritic inputs with coincidence excitation

91 emilocal density functionals, from the basic local density approximation (LDA) to our most advanced g

92 effective way of mapping the EM field or the local density of states with nanometre spatial resolutio

93 olecular electrostatic repulsions and forces local dipoles in each layer of the stacked strands to al

94 artial response, 38%; stable disease [SD] or local disease progression [DP], 13%) versus 33% of high-

95 between populations and recolonization after local disturbances.

96 the same unimodal core coalignment but form local domains of microtubules polymerizing in the same d

97 s these barriers might be useful to estimate local DOX concentrations in the tumor and in the surroun

98 sensitive to global change effects that are local (e.g., more rain in some places), which would comp

99 ur quantitative understanding of the role of local ECM size and arrangement in cell emergence-based m

100 that the effects of climatic fluctuations on local ecosystems are complex in these sensitive alpine a

101 Intravaginal drug delivery can elicit a local effect, or deliver drugs systemically without hepa

102 the molecule at [Formula: see text] has only local effects and does not have any significant impact o

103 Goltz syndrome-associated mutations and the local effects of AFR.

104 nteraction between Au NBs and QDs produces a local electric signal enhancement under Ultraviolet-visi

105 ree-band Hubbard model, which represents the local electronic structure of the copper-oxygen plane.

106 vides an electrostatic meter that will allow local electrostatic potential and energetics to be measu

107 pendence occurs at the ensemble level, where local elements are already merged into global representa

108 Local endocytic events involving receptors for axon guid

109 on activity, with G-actin immobilized by the local enrichment of phosphatidylinositol (3,4,5)-triphos

110 ue to interactions with nuclear spins in the local environment.

111 The data suggest complex local environmental response to warm climates in Antarct

112 opulations usually show adaptations to their local environments as a result of natural selection.

113 hence fluctuations, while creating distinct local environments whose functional role needs future in

114 nd phenotypically as they adapt to different local environments.

115 We found that local eQTL were more frequently mapped to adjacent genes

116 Local ERAS teams from hospitals are trained to implement

117 udy were included, which was approved by the local ethics board and written informed consent was obta

118 ls and Methods The study was approved by the local Ethics Committee, and all patients or their parent

119 spectively acquired data was approved by the local ethics committee.

120 METHODS AND We estimated local European ancestry (LEA) using Local Ancestry infer

121 Binet stage C, and was correlated with both local expansion of metabolically active bone marrow docu

122 those with mild glaucoma at baseline on the Local Eye (4.68 [6.62] vs 3.07 [5.60]) and Visual Functi

123 ernal consistency were 0.83 and 0.89 for the Local Eye and Visual Function subscales, respectively, a

124 duced repression of TGFbeta signaling in the local fibroblasts.

125 which displayed unusually strong coupling to local field potential even before seizures.

126 Our aim in the present study was to record local field potentials and unit activity from these two

127 and recorded scalp electroencephalogram and local field potentials from deep brain stimulation elect

128 Local field potentials were recorded from the subthalami

129 residues (Ser/Thr(296/297)) may perturb the local fold.

130 te in the environment and accumulate through local food webs.

131 evious models of ice age adjustment or other local (for example, tectonic) effects.

132 Our results indicate that changes in local frustration also affect partitioning in vivo betwe

133 gement in cell emergence-based migration and local gap closure.

134 re, we introduce a method for estimating the local genetic correlation between gene expression and a

135 eographic Ancestry Positioning (GAP) relates local genetic distances between samples to their spatial

136 of antigen-specific B cells were detected in local genital draining lymph nodes.

137 uperlattice, in which an evaporation-induced local gradient of NC concentration causes simultaneous n

138 re compared with what was obtained using the Local Gradient Orientation method.

139 urgery, analysed by masked central review of local histopathology reports.

140 tionally isolated microdomains, facilitating local homeostasis by redistributing ions, removing neuro

141 ncluding chemotherapeutics consistent with a local hospital waste stream.

142 l immune activation is suspected to modulate local human immunodeficiency virus (HIV) RNA levels and

143 partly explaining the mechanism of action of local hyperthermia to treat viral warts.

144 IL-1R2 plays an important inhibitory role in local IL-1- and neutrophil-dependent tissue inflammation

145 e interplay between cancer subclones and the local immune microenvironment.

146 cancer immunotherapy have focused heavily on local immune responses in the tumor microenvironment.

147 Local immunization modified favorably the course of infe

148 n anesthetic that has recently been used for local infiltration in total knee arthroplasty (TKA).

149 Mechanistically, CTRP6 regulates local inflammation and glucose metabolism by targeting m

150 properties are also observed in addition to local inflammation.

151 pithelial barrier are integral components of local inflammatory and innate immune responses.

152 igate further or to compare to more detailed local information.

153 ation of the Smad2/3 signaling axis, we used local injection of adeno-associated viral vectors (AAVs)

154 o noninvasively image kidney dysfunction and local injuries at the anatomical level.

155 to be fast, portable and avoid the need for local installation.

156 lding, which are likely defined by intrinsic local interactions between amino acids close to each oth

157 re hindered to simultaneously minimize their local interactions.

158 nd output neurons as well as region-specific local interneurons.

159 seen features are reported, highlighting the local interplay between ordered and disordered structure

160 veloped, aiming on the combined benefit of a local irradiation of the analyzed sample and a microelec

161 onset of the summer monsoon, suggesting that local land-atmosphere feedbacks involving desiccated soi

162 n of several issues such as HIPAA, state and local licensure requirements, credentialing and privileg

163 Systemic administration in mice followed by local light-emitting diode (LED)-based illumination, eit

164 eceptive fields and preclude any bias toward local light-intensity fluctuations.

165 f CCRs, but rather mimic the compositions of local lithologies.

166 DNA-damaging chemotherapy, consistent with a local loss of DDR, and identify a potential therapeutic

167 icoduodenectomy (PD) for patients treated at local, low-volume centers and those traveling to high-vo

168 Electron correlations tend to generate local magnetic moments that usually order if the lattice

169 action between conducting electron spins and local magnetic moments.

170 atomic spin and orbital magnetic moments and local magnetocrystalline anisotropy.

171 d individuals obtained in 2012 and 2013 from local markets in Madagascar, Tanzania, Vietnam and Cambo

172 nd to depend strongly on the energy level of local mesoscale eddy variability.

173 Dynamic local methylation was evident during gastrulation, which

174 during carotid endarterectomy revealed that local miR-100 expression was inversely correlated with i

175 ion, which can be maintained by bulk but not local monocarboxylates or by neuronal glycolysis.SIGNIFI

176 ctin dynamics within foot processes controls local morphology.

177 Residual local motions at the edges of the strands, underscored b

178 picosecond (tens to hundreds of picoseconds) local motions occur throughout the protein and are domin

179 the ion pore remains closed, indicating that local movements of the transmembrane helices can control

180 Local mRNA translation in growing axons allows for rapid

181 cell properties in parallel with analysis of local mucosal cytokine responses induced by nasal allerg

182 onses than inactivated vaccines by eliciting local mucosal immunity and systemic B cell- and T cell-m

183 In addition, local muscle tissue radioprotection by lead shielding du

184 assume that therapeutic effects accrue from local myocardial effects of engrafted MSCs.

185 adopt the CUFID framework and extend it for local network alignment, specifically to solve network q

186 a new view of functional diversity within a local neural population.

187 These frequencies appear to aggregate local neuronal activity, but it is unclear how this rela

188 However, above a local noise level of 20%, the model with nonspecific pla

189 Understanding how the paradox biases local observations can inform better measurements of net

190 or at the same temperature as measured by a local observer.

191 ons can learn non-linear body dynamics using local, online and stable learning rules is unclear.

192 g that occurs for molecules residing in high local optical fields of plasmonic nanostructures.

193 to such approaches, possibly contributing to local or distant recurrence.

194 ion (DBS) for Parkinson's disease (PD) under local or general anaesthesia exist, and there remains si

195 and placebo groups, and only grade 1 (mild) local or systemic adverse events occurred in both groups

196 We detected no significant differences in local or systemic adverse events or laboratory abnormali

197 s not the case; pronounced deviations of the local order from that observed in the bulk at defects an

198 ating concentrations of 25-hydroxyvitamin D, local osteoblastic conversion of 25-hydroxyvitamin D to

199 with stage 2 to evaluate possible spread of local outbreaks nationally, regionally, and internationa

200 ar nucleus (PVN) are mediated via actions on local OXT neurons in male Wistar rats.

201 eduction, suggesting a significant effect of local oxygenic photosynthesis on Pacific AMZ biogeochemi

202 ve tissue and extracellular matrix, inducing local pancreatic fibrosis and an inflammatory response.

203 ts and computationally predict the impact of local particles' environment on the recorded IR spectra.

204 cid-labile hydrazone linker as a function of local pH and time within live cells.

205 mpacted by both exports of plumes upwind and local photochemical reactions.

206 We also found that both plant size and local plant kinship negatively impact pollen dispersal a

207 g is found within these domains resulting in local polarization rotation and hence impart a mixed Nee

208 we developed an instrument for variations in local pollution concentrations that is unlikely to be co

209 ith longitudinal single-unit recordings in a local population (<1 mm(3)).

210 trials, many cells tended to covary with the local population.

211 In monkey visual area V1, nearby local populations driven by different visual stimulation

212 sity, and similarity of hospital isolates to local populations.

213 esented for HIV testing and counselling at a local primary health-care centre.

214 l secondary structure element rather than by local primary sequence.

215 aries much less drastically in space or with local primary sources.

216 techniques so far, there is a clear need for local-probe measurements.

217 We propose that this local processing enables the dense VG3-AC plexus to cont

218 es auditory delay, suggesting less efficient local processing.

219 our observations raise the possibility that local production of astrocyte proteins may support micro

220 ent, infiltration of inflammatory cells with local production of proinflammatory cytokines, and subse

221 e DC production of complement components and local production of the anaphylatoxin C5a.

222 l survival (OS), and cumulative incidence of local progression (CILP).

223 We identified 3 mechanisms underlying local progression in the remnant pancreas: (1) residual

224 onsidered to be due to blood infiltration or local proliferation, although the presence of resident h

225 portant resource for studies on the roles of local protein synthesis and axon degeneration in ALS and

226 fusion contribute to this rejuvenation, but local protein synthesis is also likely.

227 pe of secondary structure of the segment and local quality of the map.

228 tivation of RA required for tight control of local RA concentrations, is significantly downregulated

229 Thus, we demonstrate that an approach of local, randomized tailoring of bond stiffness via microa

230 The primary endpoint was time to local recurrence in the resection cavity, assessed by bl

231 The estimated local recurrence rates were 1.4% at 5 years, 1.8% at 7.5

232 ies that reported a disease-related outcome (local recurrence, nodal metastasis, distant metastasis,

233 Local recurrences following brachytherapy are uncommon 5

234 divided into two groups with a total of 151 local recurrent HCC lesions abutting the diaphragm.

235 ing the core has the potential to recover if local reductions in CBF are restored.

236 pendent protein kinase signaling, suggesting local regulation of PPARalpha.

237 We hypothesize that the local release of drug into the tumor vasculature and res

238 This case-control study was approved by the local research ethics committee.

239 al time-scales that may be attributed to the local resistivity profile at the target rear.

240 In a computational model of a local RT network featuring slow Cl(-) extrusion kinetics

241 001) than those who were seen initially at a local rural hospital.

242 nic disturbances to identify what determines local savanna vegetation heterogeneity.

243 Up-scaled local-scale results were similar to system-scale results

244 neurin) focuses and insulates termination of local second messenger responses.

245 ed immune activation associated with a large local secretion of cytokines.

246 Based on the atomic structure, we propose a local seeding model where the kinked GGA motifs in the s

247 to obtain robust estimates of the impact of local sequence features on mutation parameters and used

248 at TOP2A cleavage has functionally conserved local sequence preferences, occurs in cleavage cluster r

249 The local sequence-dependent features of DNA found in high-r

250 king them cumbersome to store and analyze on local servers.

251 iating domains, as switching markedly favors local (short-range) contacts over distant ones.

252 ty analysis further confirmed the absence of local sink-source pairs in the vStr.

253 tracellular electric fields and depletion of local sodium ion nanodomains.

254 iate broad patterns of community turnover to local, species-level effects, ultimately improving our u

255 mically induced strain can interact with the local strain existing at solid-solid interfaces.

256 , and is both induced by and stabilized with local strains generated by a network of ferroelectric do

257 essibility and stiffness, without disrupting local structural heterogeneity.

258 phous molybdenum oxyhydroxide hydrate with a local structural order composed of polyanionic trimeric

259 We found that local structure and large network distances in spatially

260 ing experiments, we have determined that the local structure of Mg1-xNixAl2O4 spinel cannot be unders

261 nucleic acids, providing valuable probes for local structure, dynamics, and ligand binding.

262 tures and hydrophobic cores, and can contain local structures not accessible with l-amino acids.

263 The local study combines these models with a database of syn

264 Whereas the local/sub-regional component is attributed to sea breeze

265 more rapidly to climatic warming compared to local summer surface air temperatures (SATs).

266 Local sweat rate and/or forearm blood flow differed as a

267 y macrophages is one pathway that suppresses local T cell proliferation.

268 h heparin is accompanied by large changes in local tau conformations and irreversible aggregation.

269 (57.4% [27 of 47] vs 7.4% [seven of 94]) and local tenderness (59.6% [28 of 47] vs 8.5% [eight of 94]

270 st cancer has raised questions about optimal local therapy for the axilla.

271 In this work, we show that the local thermal conductivity along a single Si nanowire ca

272 hese states has been limited so far to their local thermodynamic and magnetic properties, determined

273 ble kirigami metamaterials with controllable local tilting orientations on demand through prescribed

274 demonstrating negligible clearance from the local tissue 24h after delivery ex vivo.

275 e biochemical and mechanical features of the local tissue boundary.

276 sed focused ultrasound treatment groups: (a) local tissue liquefaction via boiling histotripsy, (b) t

277 e of prion sequestration and destruction via local tissue macrophages, prion trafficking by B and den

278 y of liver enzymes and histology analysis of local tissues identified differences between EBOTAb-trea

279 mmunities respond to concurrent stressors at local-to-regional scales remains largely unknown.

280 activity indexes the change in the number of local topological connections available for future trave

281 IT and the coupling of lattice strain to the local transition temperature of the phase transition.

282 demonstrate SynapTRAP's efficacy and report local translation in the cortex of mice, where we identi

283 set of universal relations which relate the local transmission, reflection, and polarization convers

284 Local treatment failure was a relatively infrequent even

285 potential of FOLH1/GCPII inhibitors for the local treatment of IBD.

286 other evaluated biometrics for prediction of local tumor recurrence after renal cell carcinoma ablati

287 Conclusion Local tumor recurrence in the NEPTR may be predicted by

288 Cancer cells exert mastery over the local tumor-associated stroma (TAS) to configure protect

289 the unit cell are related to each other by a local twofold noncrystallographic symmetry axis, a confo

290 web portal, in the cloud, or downloaded for local use, and is easily integrated with other methods f

291 We propose a model in which the local variance in tension between junctions determines w

292 trade-off between bacterial genome size and local variation in climatic conditions.

293 cortex subregions are distinctly targeted by local versus distal acupuncture electrostimulation, acup

294 upuncture electrostimulation, acupuncture at local versus distal sites may improve median nerve funct

295 monoamines serotonin and noradrenaline, and local vessel dilation is induced by glutamatergic neuron

296 ease in water usage may significantly impact local water resources.

297 extreme AOD that is attributed to increased local wildfire emissions and long-range (transcontinenta

298 ical rainforest have severe consequences for local wildlife communities.

299 Results suggested that local (within field) inoculum sources may be responsible

300 Data were collected from local youth at high risk of HIV infection and, specifica