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1 ll length, containing the N-terminal nuclear localization signal.
2 ion, although AnkG lacks a predicted nuclear localization signal.
3 mediating ligand-induced exposure of nuclear localization signal.
4 n is combined with the deletion of a nuclear localization signal.
5 ng Esp1 into the nucleus with a SV40 nuclear localization signal.
6 hanges in the STAT3 dimer masked its nuclear localization signal.
7 rescent proteins sandwiched around a nuclear localization signal.
8 reas the N-terminus contains a mitochondrial localization signal.
9 uclear export signal (NES) but not a nuclear localization signal.
10 of Staufen1 into the nucleus via its nuclear localization signal.
11 e C-terminal basic stretch and basic nuclear localization signal.
12 omains, a proline-rich region, and a nuclear localization signal.
13 in mammalian Sun1, the SUN--nuclear envelope localization signal.
14 Its N-terminus harbors a nuclear localization signal.
15 n XPNPEP3 that was devoid of a mitochondrial localization signal.
16 ely spliced exon 3, encoding a mitochondrial localization signal.
17 inhibitor or by mutating a predicted nuclear localization signal.
18 a functional coiled-coil domain and nuclear localization signal.
19 serine 114, within a PKA site in the nuclear localization signal.
20 uclear export signal and an adjacent nuclear localization signal.
21 RAF3 to the nucleus via a functional nuclear localization signal.
22 -terminal transmembrane domain and a nuclear localization signal.
23 T (residues 16 to 24) that acts as a nuclear localization signal.
24 uclei after exposure of a C-terminal nuclear localization signal.
25 95-100 kDa, which lacked N-terminal nuclear localization signals.
26 oised for activation by calcium and membrane-localization signals.
27 ieved by selectively mutating virion nuclear localization signals.
28 is regulated by small GTPase activators and localization signals.
29 nucleoplasmic sequences and 12% for nuclear localization signals.
30 , a nuclear import factor that binds nuclear localization signals.
31 se R-motifs are found in canonical nucleolar localization signals.
32 clear import of viral genome via its nuclear localization signals.
33 rowing body of work on nuclear and nucleolar localization signals.
34 e 2 (AAV2) that act as nuclear and nucleolar localization signals.
35 ied, including a bipartite classical nuclear localization signal, a mitochondrial matrix targeting se
36 ontrol its localization, including a nuclear localization signal, a nuclear retention domain and a nu
38 uced to ablate a previously reported nuclear localization signal also resulted in a significant decre
39 to as pUL31, containing a bipartite nuclear localization signal, an intrinsically disordered region
40 r targeting sequences: two classical nuclear localization signals, an INM sorting motif, and a signal
41 2 separable functional signatures, a nuclear localization signal and a putative EDGE motif, that is c
42 Mutation analysis indicated that the nuclear localization signal and both the N- and C-terminal regio
43 t exons 5-15 of kazrin, encoding the nuclear localization signal and C-terminal domain, are not requi
44 of both a peptide-encoded N-terminal nuclear localization signal and C-terminal nuclear export signal
45 iced Set-beta transcript lacking the nuclear localization signal and demonstrated that the full-lengt
47 uncated Leo1(LA1186) protein lacks a nuclear localization signal and is distributed mostly in the cyt
48 e BAG6 sequence contains a canonical nuclear localization signal and is localized predominantly in th
49 of its isoforms, DNAJB6a, contains a nuclear localization signal and regulates beta-catenin signaling
50 ior requires coordinated action of a nuclear localization signal and reversible G protein (heterotrim
51 how that ICAP1 contains a functional nuclear localization signal and that nuclear localization impair
52 oteins contain a consensus bipartite nuclear localization signal and were found in the nucleus when i
53 ng, but specific Rbfox isoforms lack nuclear localization signals and accumulate in the cytoplasm.
54 inery that recognizes one class of dendritic localization signals and establish its role in the polar
56 argeting motif that is distinct from nuclear localization signals and that can be computationally pre
57 protein coding genes encode multiple protein-localization signals and that, in 20-d-old adult fly hea
58 conserved Myc box regions but lacks nuclear localization signals and the bHLHZ domain essential for
59 inally truncated PTBP3 isoforms lack nuclear localization signals and/or most of the RRM1 domain and
61 sequence indicated the presence of a nuclear localization signal, and subcellular fractionation of LN
62 t NF-kappaB dimerization properties, nuclear localization signals, and binding to cytosolic IkappaBs
64 of selection, contain functional subcellular localization signals, and their readthrough is regulated
65 ending on TLRs' expression pattern, cellular localization, signaling, and deployment of inflammatory
70 oylation site at Lys(1172) or of the nuclear localization signal at Lys(1147) abolished L1-stimulated
71 495X FUS, which abrogates a putative nuclear localization signal at the C-terminus of FUS, in HEK-293
73 derived mutant LT (MCV350) lacking a nuclear localization signal binds hVam6p but fails to inhibit hV
74 se substrate is fused to a bipartite nuclear localization signal (bNLS) and nuclear export signal (NE
76 CK1delta catalytic activity and centrosomal localization signal (CLS) are required to rescue cilia f
80 port of proteins harboring a classic nuclear localization signal (cNLS) or the spontaneous nuclear im
81 revious studies linked the classical nuclear localization signal (cNLS) receptor, importin-alpha/Srp1
82 th with defects in M9- and classical nuclear localization signal (cNLS)-mediated protein import, nucl
86 r DCL4 transcript isoform encoding a nuclear localization signal, DCL4(NLS), is present in Arabidopsi
87 , and K376A) in conjunction with the nuclear localization signal deletion did not result in cytoplasm
88 verexpression of TEF3-1, but not its nuclear localization signal-deletion mutant (TEF3-DeltaNLS), ind
89 erexpressing exogenous FUS without a nuclear localization signal (DeltaNLS-FUS), which developed prog
90 9-Delta1/N60 fragment, which lacks a nuclear localization signal, displayed enhanced cytoplasmic vs.
92 A2 function for endosomal escape and nuclear localization signals for nuclear targeting and (ii) trig
93 d, nonactivating fatty acids inhibit nuclear localization signal formation by destabilizing this acti
94 d this localization is dictated by a nuclear localization signal found in the Adi3 T-loop extension,
96 s was restricted to the PM by fusing to a PM localization signal from the Rit GTPase, the resulting p
98 ET genes was investigated by pAtTET::NUCLEAR LOCALIZATION SIGNAL-GREEN FLUORESCENT PROTEIN/beta-GLUCU
99 amino acids of MxB to function as a nuclear localization signal; however, the ability of the N-termi
100 he interaction was mediated by two nucleolar localization signals identified by bioinformatics and mu
101 idues 11-27 and an isoleucine-lysine nuclear localization signal (IK-NLS) motif at residues 35-40.
102 ference, together with the lack of a nuclear localization signal in any of the AnkA orthologues, sugg
104 s have been shown to deteriorate the nuclear localization signal in FUS and thereby facilitate cytopl
106 hinge domain, we identified a novel nuclear localization signal in the A/B domain of thyroid hormone
107 uch nonlinear processing generates an object-localization signal in the apical dendritic tuft of laye
108 ism whereby L takes advantage of the nuclear localization signal in the COOH region of 2A to enhance
109 essing human TDP-43 with a defective nuclear localization signal in the forebrain (hTDP-43-DeltaNLS),
111 GRs or those with a mutation in the nuclear localization signal in the muscle of MGRKO mice indicate
112 lization is mediated by a complex cis-acting localization signal in the nos 3' untranslated region th
114 uttling protein, and it contains two nuclear localization signals in the basic region and one nuclear
115 sids, which leads to the exposure of nuclear localization signals in the C terminus of core protein a
117 in the nucleus through the action of nuclear localization signals in the repeated regions of the prot
118 ion studies identified and confirmed nuclear localization signals in XLG2 and XLG3 and a nuclear expo
120 expressing full-length HDM-2 with a membrane-localization signal into untransformed MCF-10-2A cells n
121 reen fluorescent protein (GFP) and a nuclear localization signal is fused to the amino terminus of GF
123 tion of NRDE-3 requires a functional nuclear localization signal, is required for nuclear RNAi, and r
124 isoform, which lacks the N-terminal nuclear localization signal, is restricted to the cytoplasm.
126 P-43 protein, as a disruption of its nuclear localization signal leads to mislocalization and aggrega
127 tead, this ability is dependent on a nuclear localization signal located in its N-terminal 40 amino a
128 ption complexes through the use of targeting/localization signals may provide new avenues for designi
129 screen for novel factors associated with RNA localization signals mediating minus end-directed mRNA t
130 LANA1(S) proteins lack an N-terminal nuclear localization signal motif, and some isoforms differ from
132 sequences do not correspond to known nuclear localization signal motifs, they represent a new motif f
134 ed with recombinant NEMO but not the nuclear localization signal mutant version and induced nuclear i
136 AP (AAP2) nuclear (NLS) and nucleolar (NoLS) localization signals near the carboxy-terminal region of
138 st substrates that carry a classical nuclear localization signal (NLS) and bind to importin alpha1, S
139 nal region of FMDV 3D that acts as a nuclear localization signal (NLS) and in template binding is als
140 evidence that Cby harbors bona fide nuclear localization signal (NLS) and nuclear export signal (NES
141 on protein between RecA containing a nuclear localization signal (NLS) and the DNA-binding domain of
143 quence analyses revealed a potential nuclear localization signal (NLS) at the C terminus of IPSE/alph
144 P24 recognizes a unique nonclassical nuclear localization signal (NLS) binding site on KPNA5 that is
146 nction genetic approach, a bipartite nuclear localization signal (NLS) derived from the nucleoplasmin
147 studies that UNE-S harbours a robust nuclear localization signal (NLS) directing SerRS to the nucleus
149 be the identification of a potential nuclear localization signal (NLS) in the C-terminal region of I2
152 thin the MeCP2 protein sequence, the nuclear localization signal (NLS) is reported to reside between
153 dy documents multifunctionality of a nuclear localization signal (NLS) located at the N-terminal regi
154 importin alpha/beta from a bipartite nuclear localization signal (NLS) located in the tail domain [14
155 analysis suggests that a monopartite nuclear localization signal (NLS) may reside in the N-terminal l
156 Consistent with the presence of a nuclear localization signal (NLS) motif within the GmHSP40.1 cod
157 on domain although it does possess a nuclear localization signal (NLS) motif, whilst Cry3 lacks both
158 hBVR nuclear export signal (NES) and nuclear localization signal (NLS) mutants demonstrated its criti
159 Here we show that mutation of the nuclear localization signal (NLS) of human Kinesin-14 HSET cause
160 acterized the importin-alpha binding nuclear localization signal (NLS) of rat ChREBP, identifying it
161 We found that, in addition to the nuclear localization signal (NLS) of XPA, importin-alpha4 or/and
162 26 and Ser828, located in a putative nuclear localization signal (NLS) on the Drosophila melanogaster
163 x virus 1 (HSV-1) mutant lacking the nuclear localization signal (NLS) on the ICP0 gene (0DeltaNLS) i
165 show that importin alpha binds to a nuclear localization signal (NLS) present in the cytoplasmic tai
166 Moreover, acetylation of Skp2 in the nuclear localization signal (NLS) promotes its cytoplasmic reten
167 ING4 is known to bind p53 via its nuclear localization signal (NLS) region and to enhance transcri
170 ed the structure and conservation of nuclear localization signal (NLS) sequences previously identifie
171 protein VP1-2 contains an N-terminal nuclear localization signal (NLS) that is critical for capsid ro
173 ting on RNA (ADAR1) carries a unique nuclear localization signal (NLS) that overlaps one of its doubl
175 otein (GFP) reporter fusion assays a nuclear localization signal (NLS) that was mapped to a 23-amino-
176 of influenza virus A/WSN/33 when its nuclear localization signal (NLS) was disrupted by R101S and R10
177 nt mouse, nBmp2NLS(tm), in which the nuclear localization signal (NLS) was inactivated to prevent nuc
178 ear localization, and a nonclassical nuclear localization signal (NLS) was mapped to a short, highly
180 port that Nurr1 contains a bipartite nuclear localization signal (NLS) within its DNA binding domain
182 f topo IIalpha, while preserving the nuclear localization signal (NLS), enhances the decatenation che
183 a cell penetrating peptide (CPP), a nuclear localization signal (NLS), or a bifunctional CPP-NLS or
184 translocated into the nucleus via a nuclear localization signal (NLS), specific among keratins, wher
185 and threonine residues adjacent to a nuclear localization signal (NLS), thereby abrogating its NLS ac
187 s required in the nucleus to release nuclear localization signal (NLS)-containing cargo from import r
189 mediate nuclear transport by linking nuclear localization signal (NLS)-containing proteins to importi
190 esmata, targeted to the nucleus in a nuclear localization signal (NLS)-dependent manner, where it loc
192 phate (RanGTP) gradient that imports nuclear localization signal (NLS)-specific cargoes (NLS-cargoes)
201 ortin alpha (Imp alpha), and variant nuclear localization signals (NLS) representing a range of bindi
202 0-nm diameter) and without (< 10 nm) nuclear localization signals (NLS), macroscopic transport rates
207 Previous studies have described one nuclear localization signal (NLSI) in p53 and speculated on two
208 idues within the peptides containing nuclear localization signals (NLSs) 1 and 2 were non-acetylated,
209 ant pathogen Phytophthora sojae uses nuclear localization signals (NLSs) for translocation of protein
210 al nucleocytoplasmic import pathway, nuclear localization signals (NLSs) in cargo proteins are recogn
211 Importin alpha1 can bind classical nuclear localization signals (NLSs) in two NLS-binding sites, kn
213 their bacterial homologues, possess nuclear localization signals (NLSs) to enter the cell nucleus du
214 proteins have been shown to contain nuclear localization signals (NLSs), although its biological rol
217 s of influenza A viruses contain two nuclear localization signals (NLSs): a well-studied monopartite
218 lpha and NRF-2beta contain intrinsic nuclear localization signals (NLSs): the Ets domain within NRF-2
220 modular signals for nuclear import (nuclear localization signals, NLSs) and export (nuclear export s
221 Here, we show that NSs contains a nucleolar localization signal (NoLS) and induces disorganization o
222 to target the nucleolus through a nucleolar localization signal (NoLS) localized between residues 33
223 leolus, and deletion of a putative nucleolus localization signal (NoLS) within its N-terminal moiety
224 nce that is predicted to contain a nucleolar localization signal (NoLS), only p8 is found in the nucl
226 orylation at S659, which exposed the nuclear localization signal of ACSS2 for importin alpha5 binding
227 sphorylation sites reside around the nuclear localization signal of Alp7, and the phosphodeficient al
228 ith point mutations in the canonical nuclear localization signal of CMAS, which relocated the enzyme
230 redicted deleterious variants in the nuclear localization signal of Heterogeneous Nuclear Ribonucleop
231 to bind to HIV-1 capsid and (ii) the nuclear localization signal of MxB, which is important for the a
233 glycerol medium, and removal of the nuclear localization signal of Rat1, the nuclear homolog of Xrn1
234 SBMA, we genetically manipulated the nuclear localization signal of the polyglutamine-expanded AR.
235 bic domain and a proximal C-terminal nuclear localization signal of VP4 were required for (i) cytolys
240 ion sites: one (short form) with the nuclear localization signal only, exclusively localized in the n
242 srupting Arl13b's palmitoylation site, cilia localization signal, or GTPase handling altered the Shh
243 trated via the assembly of stable QD-nuclear localization signal peptide bioconjugates that promoted
244 in its free form or in complex with nuclear localization signal peptides as the starting conformatio
246 not a truncated version lacking the nuclear localization signal protects from pathogenic TDP-43-medi
247 identified a novel proline-tyrosine nuclear localization signal (PY-NLS) in DJ-1, and we found that
248 portin recognizes a proline-tyrosine nuclear localization signal (PY-NLS) in the N-terminal tail of N
249 Mutations in the proline/tyrosine-nuclear localization signal (PY-NLS) of the Fused in Sarcoma pro
251 o species are due to gain/loss of cis-acting localization signals rather than to differences in the R
253 go proteins, including the classical nuclear localization signals, recognized by the adaptor importin
255 -characterized basic amino acid-rich nuclear localization signal region at positions 101 to 105, M1 c
256 onstrate that the positively charged nuclear localization signal region in the tail in apo-OsCaM61 is
259 r truncated Ptpmt1 lacking the mitochondrial localization signal restored the differentiation capabil
260 of mouse and human, and contained nucleolar localization signal, RNA-binding domain and several phos
262 ls showed that all of them contain a nuclear localization signal sequence flanking to the K1 segment
263 rthermore, despite the presence of a nuclear localization signal sequence in Gag, we observed no foam
264 The C terminus encompassing the nuclear localization signal sequesters the enzyme in the nucleus
265 g proteins (EBs) through the microtubule tip localization signal SKIP, which lies N terminal to MCAK'
266 d to nuclei, through the fusion with nuclear localization signal, still exerts strong antiproliferati
267 last targeting signal and a putative nuclear localization signal, suggesting that they are dual targe
269 tor SP1, and coexpression of SP1 and nuclear localization signal-tagged HSP27 synergistically activat
270 playing an established mitochondria-specific localization signal targets mitochondria, and that an in
272 Orc6 and Orc1 each contain a single nuclear localization signal that is essential for nuclear locali
273 hat residues (20)KY(21) constitute a nuclear localization signal that is not required for the ability
274 -1314 possesses a conserved putative nuclear localization signal that may facilitate the nuclear targ
275 elements consists of a high-affinity nuclear localization signal that mediates indirect tethering to
276 with importin alpha via a classical nuclear localization signal that recruits importin alpha to the
278 and restricting access to a primary nuclear localization signal through which the apoptogenic form i
279 by mutating Ser rich clusters of the nuclear localization signal to Ala abolished nuclear import and
281 have expressed KpnI fused to a mitochondrial localization signal to induce a specific mitochondrial d
282 rallels effects of the attachment of nuclear localization signal to Sis1, indicating that Cur1 acts o
283 very of potent Tat inhibitors that utilize a localization signal to target a dominant negative protei
284 ruction is also used in multipartite nuclear localization signals to provide broad substrate specific
285 fuse the ADAR2 domain, tagged with a nuclear localization signal, to an RNA binding peptide from bact
290 inal 25 amino acids to function as a nuclear localization signal was not required for restriction.
291 1 (FHY1) and fhy1-like, an intrinsic nuclear localization signal was proposed to be involved in the n
292 PAD4 or PADV), the only PADI with a nuclear localization signal, was previously shown to act in myel
293 tNLS algorithm uncovered a potential nuclear localization signal, whereas the algorithm DBS-Pred retu
294 t in the shorter isoform, contains a nuclear localization signal, whereas the C terminus of B56epsilo
297 dreCmas1 was mediated by a bipartite nuclear localization signal, which seemed irrelevant for other e
298 both a nuclear export sequence and a nuclear localization signal, whose activities are regulated by p
299 nd-sensing beta2 loop and a tertiary nuclear localization signal within the alpha-helical cap of the
300 ation complex is further promoted by nuclear localization signals within the nucleocapsid and integra
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