ライフサイエンスコーパス: long non-coding RNA

1 ment in group 1 ILCs that is demarcated by a long non-coding RNA.

2 enes or partially overlapping with annotated long non-coding RNAs.

3 anscripts, including pluripotency-modulating long non-coding RNAs.

4 ble base modification of unknown function in long non-coding RNAs.

5 vel RNA transcripts, likely muscle-expressed long non-coding RNAs.

6 Here we identify FILNC1 (FoxO-induced long non-coding RNA 1) as an energy stress-induced long

7 on, whereas a subset of gene transcripts and long-non-coding RNAs adjacent to TE insertions are affec

8 chanistic link between an activity-dependent long non-coding RNA and epilepsy.

9 lung adenocarcinoma transcript 1 (MALAT1), a long non-coding RNA and key positive regulator of invasi

10 rent mutations in 20 protein-coding genes, 4 long non-coding RNAs and 10 untranslational regions.

11 ariety of non-coding RNA regions (microRNAs, long non-coding RNAs and antisense transcripts), leading

12 ition, we identified a large number of novel long non-coding RNAs and fusion transcripts and found th

13 his shared liability, we identified multiple long non-coding RNAs and RNA binding protein genes (DA37

14 e stimulating articles are presented: one on long non-coding RNAs, another on the ligand-activated tr

15 Furthermore, a long non-coding RNA antisense to FOXM1 (FOXM1-AS) promot

16 that together with coding genes, (antisense) long non-coding RNAs are deregulated in skin tissue of s

17 We also find that many long non-coding RNAs are preferentially expressed in ger

18 he secondary structure of the heart-specific long non-coding RNA Braveheart, leading to the discovery

19 on-coding RNA 1) as an energy stress-induced long non-coding RNA by FoxO transcription factors.

20 ction of small RNAs by RNA polymerase IV and long non-coding RNAs by RNA polymerase V.

21 Lastly, long non-coding RNAs can serve well as associated genes

22 Many RNAs, including pre-mRNAs and long non-coding RNAs, can be thousands of nucleotides lo

23 evolutionarily conserved sequence within the long non-coding RNA CCDC26 raising the possibility of di

24 Here, we review the roles of long non-coding RNAs, chromosomal organizational structu

25 cripts, over 90% of which fulfil criteria as long non-coding RNAs correlated with the protein-coding

26 Xist, a long non-coding RNA crucial for both forms of XCI, is ac

27 Plant long non-coding RNA database (PLncDB) attempts to provid

28 MIR876), and the differential methylation of long non-coding RNA documented for the first time.

29 including both microRNAs (e.g. miR-34a) and long non-coding RNAs (e.g. lincRNA-p21).

30 umber of uncharacterized promoter-associated long non-coding RNAs encoded by the mammalian genome, th

31 X-inactive specific transcript), a prototype long non-coding RNA essential for establishing X chromos

32 Gain of PVT1 long non-coding RNA expression was required for high MYC

33 gy stress FoxOs induce the expression of the long non-coding RNA FILNC1, which inhibits survival of R

34 ested binding specificity of PRC2 to certain long non-coding RNAs for recruitment to chromatin.

35 ent findings in human cells where endogenous long non-coding RNAs function to regulate the epigenome.

36 The X-linked Xist long non-coding RNA functions as an X inactivation maste

37 approximately 2 megabases that contains the long non-coding RNA gene PVT1, the CCDC26 gene candidate

38 (ALL) cell line fuses ETV6 with the putative long non-coding RNA gene STL.

39 iverse classes of RNA, ranging from small to long non-coding RNAs, have emerged as key regulators of

40 In conclusion, the long non-coding RNA HOTAIR is directly repressed by ER a

41 Long non-coding RNAs, however, exhibit more changes in e

42 tance, and a recent study indicated that the long non-coding RNA HOX transcript antisense RNA (HOTAIR

43 ribed ultraconserved regions (T-UCRs) encode long non-coding RNAs implicated in human carcinogenesis.

44 The roles of long non-coding RNAs in cancer metabolism remain largely

45 their abundance, the molecular functions of long non-coding RNAs in mammalian nervous systems remain

46 ribes a novel function for human centromeric long non-coding RNAs in the recruitment of HJURP and CEN

47 ed for the first time an important role of a long, non-coding RNA in antigenic variation and demonstr

48 We further identify the long non-coding RNA LeXis as a mediator of this effect.

49 These include both an antisense long non-coding RNA (lncRNA) and a short PCSK6 isoform p

50 dence that the mutation and dysregulation of long non-coding RNA (lncRNA) are associated with numerou

51 Long non-coding RNA (lncRNA) are emerging as contributor

52 hylation of DNA by RdDM is the production of long non-coding RNA (lncRNA) by RNA polymerase V (Pol V)

53 ak association lies upstream of LOXL1-AS1, a long non-coding RNA (lncRNA) encoded on the opposite str

54 The discovery of long non-coding RNA (lncRNA) has dramatically altered ou

55 Here we report that the long non-coding RNA (lncRNA) HOTAIR (for HOX Transcript

56 r nuclear factor kappa B (NF-kappaB) and the long non-coding RNA (lncRNA) HOTAIR (HOX transcript anti

57 Here, we show that NEAT1 long non-coding RNA (lncRNA) is a direct transcriptional

58 Long non-coding RNA (lncRNA) is a large class of gene tr

59 e other transcript variants, indicating that long non-coding RNA (lncRNA) is processed after transcri

60 We identified a rodent-specific long non-coding RNA (lncRNA) linc1281, hereafter Ephemer

61 MATR3 also binds and regulates the levels of long non-coding RNA (lncRNA) Neat1 and together with PAB

62 yses, including coding-transcript profiling, long non-coding RNA (lncRNA) profiling and coexpression

63 21, P = 5.06 x 10(-8); OR = 1.15) within the long non-coding RNA (lncRNA) RP11-58A18.1 and ~500 kb fr

64 y shown that mice with genetic knockout of a long non-coding RNA (lncRNA) steroid receptor RNA activa

65 We identified a long non-coding RNA (lncRNA) that arises from the antise

66 ied a cis-regulatory element demarcated by a long non-coding RNA (lncRNA) that controls the function

67 rrelates with the expression of an antisense long non-coding RNA (lncRNA) that has previously been sh

68 PCGEM1 is a long non-coding RNA (lncRNA) that is often upregulated i

69 effective for muscle knockdown of Malat1, a long non-coding RNA (lncRNA) that is retained in the nuc

70 m(6)A alters the local structure in mRNA and long non-coding RNA (lncRNA) to facilitate binding of he

71 he imprinted minimal PWS locus encompasses a long non-coding RNA (lncRNA) transcript processed into m

72 Long non-coding RNA (lncRNA) transcription into a downst

73 Clustering by mRNA, long non-coding RNA (lncRNA), and miRNA expression conve

74 Active transcription of the neuron-specific long non-coding RNA (lncRNA), UBE3A-ATS, has been shown

75 The intronless ht-WNT10B resembles a long non-coding RNA (lncRNA), which suggests its involve

76 Several lines of evidence suggest that long non-coding RNA (lncRNA)-dependent mechanisms regula

77 Alu element in a cytoplasmic, polyadenylated long non-coding RNA (lncRNA).

78 of uncharacterized non-coding RNAs including long non-coding RNA (lncRNA).

79 The human genome is replete with long non-coding RNAs (lncRNA), many of which are transcr

80 A central element of this process are long non-coding RNAs (lncRNA), which in Arabidopsis thal

81 g have enabled the discovery of thousands of long non-coding RNAs (lncRNAs) across many species.

82 Many long non-coding RNAs (lncRNAs) affect gene expression, b

83 RNA exosome and identified a vast number of long non-coding RNAs (lncRNAs) and enhancer RNAs (eRNAs)

84 Long non-coding RNAs (lncRNAs) are a diverse and poorly

85 Long non-coding RNAs (lncRNAs) are a diverse class of RN

86 Long non-coding RNAs (lncRNAs) are a family of novel gen

87 Long non-coding RNAs (lncRNAs) are a fascinating, but st

88 Long non-coding RNAs (lncRNAs) are a kind of RNAs with r

89 Long non-coding RNAs (lncRNAs) are a novel class of regu

90 Long non-coding RNAs (lncRNAs) are a novel class of tran

91 Recent studies suggest that the long non-coding RNAs (lncRNAs) are also involved in many

92 Long non-coding RNAs (lncRNAs) are an emerging class of

93 Alterations in long non-coding RNAs (lncRNAs) are associated with human

94 In these tumors, expression of long non-coding RNAs (lncRNAs) are deregulated and close

95 these transcriptomic responses and show that long non-coding RNAs (lncRNAs) are dynamically regulated

96 Long non-coding RNAs (lncRNAs) are emerging as new playe

97 Novel, profound and unexpected roles of long non-coding RNAs (lncRNAs) are emerging in critical

98 Long non-coding RNAs (lncRNAs) are expressed in a highly

99 A transcripts such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are important genetic reg

100 ial, and growing evidence has indicated that long non-coding RNAs (lncRNAs) are important players in

101 Long non-coding RNAs (lncRNAs) are important regulators

102 To identify what long non-coding RNAs (lncRNAs) are involved in non-small

103 Long non-coding RNAs (lncRNAs) are largely heterogeneous

104 Although long non-coding RNAs (lncRNAs) are non-protein-coding tr

105 Long non-coding RNAs (lncRNAs) are not translated into p

106 Early reports indicate that long non-coding RNAs (lncRNAs) are novel regulators of b

107 To date, Y chromosome-linked long non-coding RNAs (lncRNAs) are poorly characterized

108 Long non-coding RNAs (lncRNAs) are potentially important

109 As long non-coding RNAs (lncRNAs) are prominent regulators

110 Long non-coding RNAs (lncRNAs) are prominently associate

111 We evaluated the potential of circulating long non-coding RNAs (lncRNAs) as biomarkers of subclini

112 Long non-coding RNAs (lncRNAs) can recruit PRC2 to chrom

113 Long non-coding RNAs (lncRNAs) comprise a diverse class

114 Long non-coding RNAs (lncRNAs) constitute a large, yet m

115 Most long non-coding RNAs (lncRNAs) encoded by eukaryotic gen

116 Although the functional role for long non-coding RNAs (lncRNAs) has been best defined in

117 More recently, long non-coding RNAs (lncRNAs) have attracted much atten

118 While functional roles of several long non-coding RNAs (lncRNAs) have been determined, the

119 Although many long non-coding RNAs (lncRNAs) have been discovered, the

120 Several of the thousands of human long non-coding RNAs (lncRNAs) have been functionally ch

121 Thousands of long non-coding RNAs (lncRNAs) have been identified in m

122 Long non-coding RNAs (lncRNAs) have been implicated in d

123 Long non-coding RNAs (lncRNAs) have been implicated in n

124 Long non-coding RNAs (lncRNAs) have been implicated in t

125 To date, a large number of long non-coding RNAs (lncRNAs) have been recently discov

126 Long non-coding RNAs (lncRNAs) have been shown to be cri

127 For example, although long non-coding RNAs (lncRNAs) have been shown to critic

128 Recently, long non-coding RNAs (lncRNAs) have emerged as an import

129 Long non-coding RNAs (lncRNAs) have emerged as important

130 Long non-coding RNAs (lncRNAs) have emerged as potential

131 Long non-coding RNAs (lncRNAs) have emerged as regulator

132 h a small number of the vast array of animal long non-coding RNAs (lncRNAs) have known effects on cel

133 In particular, the biological roles of long non-coding RNAs (lncRNAs) have never been character

134 Long non-coding RNAs (lncRNAs) have recently been found

135 Transcription-regulating long non-coding RNAs (lncRNAs) have the potential to con

136 Further, ethanol-induced upregulation of long non-coding RNAs (lncRNAs) HOTAIR and MALAT1 in endo

137 In addition to widespread transcription of long non-coding RNAs (lncRNAs) in mammalian cells, bidir

138 Moreover, through screening hypoxia-related long non-coding RNAs (lncRNAs) in PDK1-positive tissue,

139 hough recent studies have indicated roles of long non-coding RNAs (lncRNAs) in physiological aspects

140 The roles of long non-coding RNAs (lncRNAs) in regulating cancer and

141 m comparable, with a distinct enrichment for long non-coding RNAs (lncRNAs) in snRNA-seq.

142 ealed the transcription of a wide variety of long non-coding RNAs (lncRNAs) in the genomes of several

143 TA databases indicated similarity with plant long non-coding RNAs (lncRNAs) involved in splicing regu

144 The expression of long non-coding RNAs (lncRNAs) is dysregulated in hepato

145 Thousands of long non-coding RNAs (lncRNAs) lie interspersed with cod

146 nal to zygotic transition and annotated 1120 long non-coding RNAs (lncRNAs) many of which differentia

147 We hypothesized that circulating long non-coding RNAs (lncRNAs) may act as diagnostic mar

148 There is a growing perception that long non-coding RNAs (lncRNAs) modulate cellular functio

149 Long non-coding RNAs (lncRNAs) play critical roles in di

150 New evidence indicates that long non-coding RNAs (lncRNAs) play crucial roles in epi

151 Long non-coding RNAs (lncRNAs) play key roles in human d

152 specific gene promoters is also mediated by long non-coding RNAs (lncRNAs) produced by RNA polymeras

153 other mammalian genomes produce thousands of long non-coding RNAs (lncRNAs) raises many fascinating q

154 It is increasingly clear that long non-coding RNAs (lncRNAs) regulate a variety biolog

155 Long non-coding RNAs (lncRNAs) regulate diverse biologic

156 Although long non-coding RNAs (lncRNAs) regulate various cellular

157 Long non-coding RNAs (lncRNAs) regulating gene expressio

158 ost response to infection, the roles of many long non-coding RNAs (lncRNAs) remain unknown.

159 Despite the overwhelming number of human long non-coding RNAs (lncRNAs) reported so far, little i

160 Increasing evidence suggests that long non-coding RNAs (LncRNAs) represent a new class of

161 Circulating long non-coding RNAs (lncRNAs) serve as valuable biomark

162 c deletion strategy to screen for functional long non-coding RNAs (lncRNAs) that is based on a lentiv

163 sent here a workflow to identify and analyze long non-coding RNAs (lncRNAs) via RNA-Seq data.

164 Over 3,000 genes encoding previously unknown long non-coding RNAs (lncRNAs) were revealed through the

165 efforts have vastly expanded the catalog of long non-coding RNAs (lncRNAs) with varying evolutionary

166 that detect and repair DNA damage, in which long non-coding RNAs (lncRNAs), a new class of regulator

167 ripts, including primary microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and enhancer RNAs (eRNAs

168 nt and gene silencing are thought to involve long non-coding RNAs (lncRNAs), but few specific lncRNAs

169 ed in a cell-type-specific manner, producing long non-coding RNAs (lncRNAs), rather than protein-codi

170 s such as small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs), undergo trans-splicing a

171 mong putatively ERalpha-regulated intergenic long non-coding RNAs (lncRNAs), we identified nuclear en

172 Long non-coding RNAs (lncRNAs), which are non-coding RNA

173 Long non-coding RNAs (lncRNAs), which have evolved as im

174 vasively transcribed to produce thousands of long non-coding RNAs (lncRNAs).

175 ammalian genomes encode tens of thousands of long non-coding RNAs (lncRNAs).

176 g both short non-coding RNAs (microRNAs) and long non-coding RNAs (lncRNAs).

177 ing frames (ORFs) and which have been termed long non-coding RNAs (lncRNAs).

178 will be translated (mRNAs) from the class of long non-coding RNAs (lncRNAs).

179 as helped to reveal a large transcriptome of long non-coding RNAs (lncRNAs).

180 cripts make up the non-coding RNAs including long non-coding RNAs (lncRNAs).

181 oaches have identified thousands of putative long non-coding RNAs (lncRNAs).

182 oteins, and a significant subset of them are long non-coding RNAs (lncRNAs).

183 anisms that regulate gene expression such as long non-coding RNAs (lncRNAs).

184 mes are transcribed into numerous regulatory long non-coding RNAs (lncRNAs).

185 nal annotation or no protein product such as long non-coding RNAs (lncRNAs).

186 o provide the following functions related to long non-coding RNAs (lncRNAs): (i) Genomic information

187 nse-associated region contains two genes for long, non-coding RNAs (lncRNAs), AL157359.3 and AL157359

188 nces are disproportionately present in human long, non-coding RNAs (lncRNAs).

189 products generated by ASOs targeting nuclear long non-coding RNA Malat 1 and pre-mRNA were degraded b

190 sequences derived from a non-polyadenylated long non-coding RNA (MALAT1), which can form a stabilizi

191 iduals with hypereosinophilic syndrome, this long non-coding RNA may represent a potential therapeuti

192 ion, thereby showing that circularization of long non-coding RNAs may alter RNA function and protect

193 ogical significance of metastasis-associated long non-coding RNA, metastasis-associated lung adenocar

194 ebra finch brain, altering the expression of long non-coding RNAs, microRNAs, transcription factors a

195 transcriptional profiling, we found that the long non-coding RNA MIR100HG and two embedded microRNAs,

196 to this scenario when it was shown that the long non-coding RNA molecule lincRNA-p21, known to be in

197 pression of 110 RNA-binding proteins and 137 long non-coding RNAs, most of them previously not linked

198 and their impact on expression of the linked long non-coding RNA, Nctc1.

199 tion also requires transcription in cis of a long non-coding RNA, Nctc1.

200 F4A1, the tumor suppressor gene PTEN and the long non-coding RNA NEAT1.

201 set of specialized proteins assembled on the long non-coding RNA NEAT1; they have a role in nuclear r

202 aspeckles are nuclear bodies form around the long non-coding RNA, Neat1, and RNA-binding proteins.

203 Here we show that the long non-coding RNA, NEAT1, directly modulates neuronal

204 kles are built co-transcriptionally around a long non-coding RNA, NEAT1.

205 CODE and modENCODE, and as interest grows in long non-coding RNAs, often initially recognized by thei

206 actors including regulators of pluripotency, long non-coding RNAs, or the presence of architectural p

207 The long non-coding RNA PARTICLE (Gene PARTICL- 'Promoter of

208 ependence of high MYC protein levels on PVT1 long non-coding RNA provides a much needed therapeutic t

209 g messenger RNAs and non-coding RNAs such as long non-coding RNAs, pseudogenes and circular RNAs.

210 (P=1.42 x 10(-12)), 8p12 at lnc-KIF13B-1, a long non-coding RNA (rs643472; P=3.41 x 10(-8)), and 2p2

211 t study, Leucci et al. report a role for the long non-coding RNA SAMMSON in driving mitochondrial fun

212 t advances suggest that chromatin-associated long non-coding RNA scaffolds also recruit chromatin-mod

213 The long non-coding RNA SChLAP1 was identified as the highes

214 ger in length and represent a novel class of long, non-coding RNA species.

215 the translation product of the bi-functional long non-coding RNA steroid receptor activator RNA 1 (SR

216 Although long non-coding RNAs such as HOTAIR have been implicated

217 HOTAIR is a long non-coding RNA that interacts with the polycomb rep

218 HOTAIR is a long non-coding RNA that is overexpressed, promotes meta

219 N-BLR is a primate-specific long non-coding RNA that modulates the epithelial-to-mes

220 Here we identify a long non-coding RNA that we termed Morrbid, which tightl

221 Long non-coding RNAs that are expressed from the opposit

222 Notably, ZNF750 promoted the expression of a long non-coding RNA (TINCR), which mediated both cancer-

223 They describe how a primate-specific long non-coding RNA titrates the levels of a microRNA th

224 , but also reveals a regulatory mechanism by long non-coding RNAs to control energy metabolism and tu

225 luster of nearly 40 microRNAs and their host long non-coding RNA transcript (lnc-MGC) are coordinatel

226 s between the proteins involved in small and long non-coding RNA transcriptional regulatory mechanism

227 address this issue, here we characterize the long non-coding RNA transcriptome in primary human monoc

228 f-origin-specific expression of two opposing long non-coding RNAs, Tsix and Xist, in mice.

229 s intact but silenced by a nuclear-localized long non-coding RNA, UBE3A antisense transcript (UBE3A-A

230 , the abundance of many miRNA precursors and long non-coding RNAs was dramatically altered in THC-tre

231 y cohort, all protein-coding genes and known long non-coding RNAs were ranked by fold change in expre

232 how that transcription of a Hand2-associated long non-coding RNA, which we named upperhand (Uph), is

233 stantly-acting control elements of antisense long non-coding RNAs, which in turn regulate targeted ge

234 d 1200 protein coding genes (PCGs) and 100 long non-coding RNAs with domestication-associated haplo

235 chromatin domain and induces expression of a long non-coding RNA within the upstream promoter region

236 The long non-coding RNA X-inactive specific transcript (XIST

237 Notably, expression and coating by the long non-coding RNA XACT are early events in XCI erosion

238 genetic silencing in which expression of the long non-coding RNA XIST initiates the heterochromatiniz

239 The process of XCI is dependent upon the long non-coding RNA Xist, which is expressed from and co

240 The master regulator of this process is the long non-coding RNA Xist.

241 is initiated by upregulation of the lncRNA (long non-coding RNA) Xist and recruitment of specific ch

242 Here we discover an Xist antisense long non-coding RNA, XistAR (Xist Activating RNA), which

243 Interestingly, a long non-coding RNA, ZEB2NAT, was demonstrated to be ess