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1 ociated with linking inorganic elements into long chains.
2 ngth, with Fermi level crossing observed for long chains.
3 sed were unable to optimally search over all long chains.
4 everity of neuropathy and the levels of very-long-chain 1-deoxyceramides such as C24 (P < 0.05), with
5 sm that enables Hydra to specifically modify long-chain 3-oxo-homoserine lactones into their 3-hydrox
7 86, Subfamily A, Polypeptide2 (CYP86A2) and Long Chain Acyl Synthetase2 (LACS2), which catalyze two
9 mice decreased acetylation of mitochondrial long-chain acyl-CoA dehydrogenase, a known SIRT3 deacety
13 f cardiac lipotoxicity overexpressing ACSL1 (long-chain acyl-CoA synthetase 1) in cardiomyocytes, we
16 This study revealed a central role of the long-chain acyl-CoA synthetase LCS2 in the production of
17 s a prodrug that requires activation by very long-chain acyl-CoA synthetase-1 (ACSVL1) to modulate bo
21 Recent findings indicate that inhibition of long-chain acyl-CoA synthetases with triacsin C, a fatty
22 KO) mice have lower ECHA activity, increased long-chain acyl-CoAs, and decreased ATP in the heart und
24 nfrared microspectroscopy, the cutin mutants long-chain acyl-coenzyme A synthetase2 (lacs2), permeabl
27 odel in which oxy-Mb is a novel regulator of long-chain acylcarnitine and fatty acid pools in Mb-rich
29 P = .01, .04, and .05, respectively), and 1 long-chain acylcarnitine metabolite (palmitoyl carnitine
32 ted metabolomics studies showed that several long-chain acylcarnitines (10:1, 12:0, 12:2, 18:1, and 1
33 evels of free fatty acid, ketone bodies, and long-chain acylcarnitines and 2) cardiac triglyceride ac
36 Human RV long-chain FAs were increased and long-chain acylcarnitines were markedly reduced in PAH v
37 eline concentrations of short-, medium-, and long-chain acylcarnitines who were randomly assigned to
39 of myocardial lipid intermediates, including long-chain acylcarnitines, the primary subset of energet
40 ell established activities of the sirtuins, "long chain" acyllysine modifications were also shown to
41 ganic ice-nucleating surfaces, monolayers of long chain alcohols are particularly effective, while mo
44 ble cavitands in the Staudinger reduction of long-chain aliphatic diazides (C8 , C10 , and C12 ).
46 Affimer characterization was achieved using long-chained alkanethiol linkers coupled with oligoethyl
50 construction of imide and amide bonds with a long-chain alkyl group is an attractive feature of this
51 from serum or water on glass substrates via long-chain alkyls and tagged with reporter gold nanopart
54 we studied structural features of the novel long chains and analyzed the assembly of these into tetr
56 as not compensated by enhanced generation of long-chain apocarotenals but resulted in higher levels o
57 tpI-4 protein may facilitate the transfer of long-chain as well as very-long-chain fatty acids into t
58 evealed that like the alpha3 chain the novel long chains assemble to homotetramers that are incorpora
60 atty acyl (C18) ceramide, cause elevation of long-chain base (LCB) substrates and decrease in C18 cer
61 ough an additional hydroxyl in the sphingoid long-chain base slightly destabilized the ceramide's int
63 en coexpressed with Arabidopsis SPT subunits long-chain base1 (LCB1) and LCB2 and the small subunit o
65 biosynthetic precursors, including sphingoid long chain bases and ceramides, have important signaling
66 levels of RSB1, which encodes an exporter of long chain bases dihydrosphingosine (DHS) and phytosphin
67 long-chain fatty acids (VLCFA) and sphingoid long-chain bases, which are amide linked to form ceramid
69 activity, this enzyme can use cellobiose and long-chain cellodextrins with a degree of polymerization
71 Pharmacological analysis demonstrated that long-chain ceramide regenerated from C6-ceramide through
72 showed strong specificity, interacting with long chain chitooligosaccharides but not with maltooligo
73 through by general diffusion while allowing long chain chitooligosaccharides to pass through by a fa
75 the complex mixture of short-, median-, and long-chain CPs (SCCPs, MCCPs, and LCCPs) in Australian s
79 rt-chain congeners, polycondensates based on long-chain difunctional monomers are often dominated by
80 clusively for the dominating Dols, while for long-chain Dols, the relative input of the MEP and MVA p
83 anisms underlying protection include reduced long chain FA uptake, shifts in FA distribution (lipidom
85 y acid receptor (FFAR) 1 (FFA1), which binds long-chain FA (LCFA), and SCFA receptors FFA2 and FFA3 w
87 e first time, higher bioaccessibility of the long-chain FAs than the short- and medium-chain FAs was
90 provide insight into the regulation of very long chain fatty acid (VLCFA) biosynthesis in Brassica n
92 ter interface in presence of model saturated long chain fatty acid and alcohol surfactants, nonanoic
93 presence of protective mechanisms toward the long chain fatty acid effects in bacteria belonging to C
94 etwork is necessary for ileal propionate and long chain fatty acid sensing to regulate glucose homeos
95 longases that catalyze the synthesis of very long chain fatty acids (C24 to C26) required for ceramid
96 recyclable, due to incomplete degradation of long chain fatty acids (LCFA) released during lipids hyd
100 he metabolic regulator factors elongation of long chain fatty acids 7 (Elovl7) and cytochrome B5 redu
101 scribe the structure of CD36 in complex with long chain fatty acids and a CD36-binding PfEMP1 protein
103 dratases are required for elongation of very long chain fatty acids, and HACD1 has a role in early my
109 We showed that NLMs lost saturated very-long-chain fatty acid (FA; C24:0) SM in cancer cells and
110 chefflera elegantissima) contained only very-long-chain fatty acid (VLCFA) derivatives such as alcoho
113 ons with apolar molecules; both hexane and a long-chain fatty acid belonging to the quorum-sensing sy
115 growth in mucus and on plates containing the long-chain fatty acid oleate as the sole carbon source.
116 that ACAD9 knockout in HEK293 cells affected long-chain fatty acid oxidation along with Cl, both of w
117 loss of an obligate enzyme in mitochondrial long-chain fatty acid oxidation, carnitine palmitoyltran
119 showed an enrichment of 2-hydroxylated very-long-chain fatty acid-containing GIPCs and polyglycosyla
122 , suggesting that enhanced synthesis of very-long-chain fatty acid/trihydroxy LCB ceramides promotes
123 alls and found a reduction in the amounts of long-chain fatty acids (C18:0) in the atltpI-4 mutant.
124 e the importance of oxidation of blood-borne long-chain fatty acids (Fa) in the cardiomyocytes for co
127 ct in synthesis of unsaturated long and very long-chain fatty acids (LCFAs and VLCFAs) and depletion
130 ingolipids are synthesized de novo from very long-chain fatty acids (VLCFA) and sphingoid long-chain
131 ccumulation of peroxisomal educts (like very-long-chain fatty acids [VLCFAs] or branched-chain fatty
132 ent mitochondrial model of beta-oxidation of long-chain fatty acids and main energy-redox processes i
133 art and muscle reduced complete oxidation of long-chain fatty acids by 87 and 69%, respectively, with
134 is led to a significant increase in the very-long-chain fatty acids C24 and C26 in the cuticular wax
136 ietary and bacteria-derived medium-chain and long-chain fatty acids exacerbate, whereas short-chain f
137 tabolomics analysis, we found an increase in long-chain fatty acids in BMPR2 mutant mouse RVs compare
138 Cs and sterols and suggested a role for very-long-chain fatty acids in the interdigitation between th
139 ACAD9 also retains enzyme ACAD activity for long-chain fatty acids in vitro, but the biological rele
140 mportation of docosohexaenoic acid and other long-chain fatty acids into fetal and adult brain and is
141 tions in ABCD1 lead to incorporation of very-long-chain fatty acids into phospholipids, we separately
142 e the transfer of long-chain as well as very-long-chain fatty acids into the apoplast, depending on t
143 without fatty acids, but in the presence of long-chain fatty acids is "switched on" as a proton tran
144 mation, whereas supplementation with omega 3 long-chain fatty acids protect against intestinal inflam
146 d bioactive molecules that include amides of long-chain fatty acids with taurine [N-acyl-taurines (NA
147 oline species containing polyunsaturated and long-chain fatty acids, indicating the presence of matur
148 noleic acid, odd-chain fatty acids, and very long-chain fatty acids, was associated with lower incide
149 he upper surface of the petal is enriched in long-chain fatty acids, which are constituents of the wa
152 tabolism and vacuolar morphology through the long-chain fatty acyl-CoA synthetase Faa1, independently
153 ember 2 (Them2) is a mitochondria-associated long-chain fatty acyl-CoA thioesterase that is activated
154 requires strict control of the metabolism of long-chain fatty acyl-CoAs because of the multiplicity o
155 of class II ceramide synthases that use very-long-chain fatty acyl-coenzyme A and trihydroxy LCB subs
156 hyde-deformylating oxygenase (cADO) converts long-chain fatty aldehydes to alkanes via a proposed dif
160 though AH-7614 did not antagonize the second long-chain free fatty acid receptor, free fatty acid rec
162 monoacylglycerol, glycerol, and medium- and long-chain free fatty acids, reflective of lipid mobiliz
163 pounds of low volatility, such as medium and long-chain free fatty acids, whereas compounds with high
164 ed in photoreceptor cells and generates very long chain (>/=C28) polyunsaturated fatty acids includin
166 al isolates also displayed strong binding to long-chain "human-like" alpha2,6-linked sialic acids and
168 rogenation of carbon monoxide (CO), produces long chain hydrocarbons and offers an alternative to the
169 ecific nature of the interaction between the long-chain hydrocarbons and the hydrophobic amino acids.
170 While traditionally mainly methanol and long-chain hydrocarbons are produced by CO hydrogenation
172 ates for the cleavage of C-C single bonds in long-chain hydrocarbons, we analyzed protein structures
174 suggest that 1-deoxysphingolipids, the very-long-chain in particular, play a role as molecular inter
175 formed between charged micelles (i.e., from long chain ionic surfactants) and neutral cyclodextrins
176 dicated that the cardioprotective effects of long-chain (LC) n-3 (omega-3) polyunsaturated fatty acid
177 about the metabolic fate of the intermediary long-chain (LC) n-3 polyunsaturated fatty acid (PUFA) do
180 selectivities for the biphasic production of long-chain linear aldehydes under benign aqueous conditi
181 lipid order, indicating that segregation of long-chain lipids into myelin sheets is a process specif
190 of gamma-linolenic acid, palmitic acid, and long-chain monounsaturated fatty acids, and it explained
197 ermine whether supplementation with 2.7 g of long-chain n-3 polyunsaturated fatty acids in pregnancy
199 owing FA intervention, a reduction in plasma long-chain n-3 PUFA was associated with a reduction in a
200 dietary intake and adipose tissue content of long-chain n-3 PUFAs and subsequent 5-y change in body w
201 Dietary intake and adipose tissue content of long-chain n-3 PUFAs were neither consistently nor appre
205 gher proportions of certain VLC n-3 and very long-chain n-6 PUFAs in plasma phospholipids at age 8 ye
206 at the same reaction can be tuned to produce long-chain n-aldehydes, 1-alcohols and olefins, as well
207 hanogenic consortium capable of mineralizing long-chain n-paraffins (C28 -C50 ) was enriched from San
208 he very short synthesis of highly stereopure long-chain natural products containing remote, methyl-be
210 butyl) rather than the ones with medium and long chains (octyl, dodecyl, hexadecyl and eicosyl).
212 o distinct forms of soft matter, composed of long chains of covalently and noncovalently linked struc
213 cturally extremely simple, polyP consists of long chains of covalently linked inorganic phosphate gro
214 ylogenetically diverse microbes that produce long chain, olefinic hydrocarbons have received much att
216 This new microalga can be cultivated for long chain omega-3 fatty acids and lutein production in
220 To assess the efficacy of 2 forms of oral long-chain omega-3 (omega-3) essential fatty acid (EFA)
223 ion.We tested the effects of high-dose, very-long-chain omega-3 fatty acids on adipose tissue inflamm
224 ontain a rich source of the health promoting long-chain omega-3 fatty acids, eicosapentaenoic (EPA) a
225 ffer in fatty acid composition, specifically long-chain omega-3 polyunsaturated fatty acid (LCPUFA) c
227 or psychosis is dietary supplementation with long-chain omega-3 polyunsaturated fatty acids (PUFAs).
230 ed fraction was almost consistently >50% for long-chain perfluoroalkyl carboxylates and sulfonates (>
233 atively low drinking water concentrations of long-chain PFAAs substantially increase human body burde
235 online SPE-HPLC-MS/MS was used to measure 10 long-chain PFASs in serum from blood collected cross-sec
236 on a limited selection of rather well-known long-chain PFASs, particularly perfluorooctanesulfonate
238 heir term infants, we measured PFOA and four long-chain PFCAs (ng/mL) in third-trimester maternal ser
240 t atmospheric inputs (via precursors) of the long-chain PFCAs are important contributors in the study
244 , due to increasing hydrophobicity, with the long-chain phosphonium ILs being toxic while the shorter
245 ents have revealed that mammals, fungal, and long-chain plant cis-PTs are heteromeric enzymes compose
246 s, mechanical behavior, and degradability of long-chain polyester, polyamides, polyurethanes, polyure
250 arly stage accompanied by the dissolution of long-chain polysulfide, and solid-state transition from
251 eiving breast milk with higher levels of n-3 long chain polyunsaturated (LCP) fatty acids (OR 0.50; 9
252 Fish fed the CS diet had significantly more long chain polyunsaturated fatty acid than had those fed
253 nterest in the de novo production of omega-3 long chain polyunsaturated fatty acids such as eicosapen
254 in, targets liver cancer cells and increases long chain polyunsaturated fatty acids, but decreases ce
257 9-week experimental feeding period to reduce long-chain polyunsaturated fatty acid (LC-PUFA) and pers
259 othesized that the n-6:n-3 (omega-6:omega-3) long-chain polyunsaturated fatty acid (LCPUFA) ratio in
260 shed 15%-30% after adjustment for mercury or long-chain polyunsaturated fatty acid concentrations.
261 adjusted for umbilical cord blood mercury or long-chain polyunsaturated fatty acid concentrations.
262 sted that docosahexaenoic acid (DHA), an n-3 long-chain polyunsaturated fatty acid, might reduce the
263 ized in the stroma, then converted into very-long-chain polyunsaturated fatty acids (FAs) at the endo
264 strated to have the ability to biosynthesize long-chain polyunsaturated fatty acids (LC-PUFA) from C1
265 a daily intake of up to 500 mg omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA) is reco
267 t increased maternal intake of omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFAs) during
268 ntal studies show that dietary omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFAs) reduce
274 nt formulas in the United States contain the long-chain polyunsaturated fatty acids (PUFAs) docosahex
275 d perinatal periods, many nutrients, such as long-chain polyunsaturated fatty acids [contained in fis
276 l studies suggest that levels of n-3 and n-6 long-chain polyunsaturated fatty acids are associated wi
278 are markedly enriched in omega-3 and omega-6 long-chain polyunsaturated fatty acids, which others hav
280 n of main group elements (groups 13-16) into long chains provides access to materials with fascinatin
282 n stunting and low serum omega-3 and omega-6 long-chain PUFAs, which are essential for growth and dev
283 y, gas phase enthalpies of formation of many long chain saturated and unsaturated fatty acids and of
284 hment in sterols and sphingolipids with very long chain saturated fatty acids when compared with the
286 s show significantly greater accumulation of long-chain saturated ceramides that are substrate for AC
287 FAs and low n-6 (omega-6) FAs, 2) high very-long-chain saturated FAs, 3) high n-3 (omega-3) FAs, 4)
288 tearic acid, odd-chain fatty acids, and very-long-chain saturated fatty acids and low concentrations
289 geted lipidomics strategies, we identify two long-chain saturated NATs-N-tetracosanoyl-taurine [NAT(2
291 ally and classified into short-, medium-, or long-chain scores, in a case-cohort study within the Pre
292 are associated with diabetes; however, very-long-chain SFAs (VLSFAs), with 20 or more carbons, diffe
293 entrations of Tg and Tg analogs with various long-chain substitutions at the O-8 position extensively
294 multiple linear regression revealed that the long-chain-to-intermediate-chain acylcarnitine ratio inv
296 prene, E. ulmoides has evolved to synthesize long-chain trans-polyisoprene via farnesyl diphosphate s
297 Finally, we report that resting levels of long-chain triacylglycerols in mitochondrial myopathy co
298 h lower levels of mycolic acid wax ester and long-chain triacylglycerols than those for wild-type bac
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