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1  triggers uncoating is a pivotal question of long standing.
2                                          The long-standing acid growth theory postulates that auxin t
3  the causes of cis-regulatory variation is a long-standing aim in evolutionary biology.
4           Imaging single proteins has been a long-standing ambition for advancing various fields in n
5                                            A long-standing ambition in ecosystem science has been to
6 eracting magnetic fine particle systems is a long standing and difficult inverse problem.
7                   In this review, we discuss long-standing and recent evidence supporting the occurre
8 ral catalytic Chan-Lam amination, overcoming long-standing and unsolved amine and organoboron limitat
9                                         As a long-standing and widely used web application for functi
10 etation of statistical methods and tests are long-standing and widespread.
11 l studies are warranted to determine whether long-standing anterior uveitis increases risk of endothe
12            Synthetic organic chemists have a long-standing appreciation for transition metal cyclopen
13                                     However, long-standing archaeological emphasis on typological ana
14          Furthermore, this code disavows the long-standing assumption that face cells encode specific
15 different end wall types, contradicting this long-standing assumption.
16                While such relapse has been a long-standing battle in craniofacial care of patients, c
17 ding of stomatal mechanics and questions our long-standing beliefs about structurally important facto
18                                         As a long-standing biomedical model, rats have been frequentl
19                          Thus, CLS removes a long-standing bottleneck in transcriptome annotation and
20                                            A long-standing but fundamental question in lightning stud
21 euronal nets (PNNs) enwrapping PV+ cells are long-standing candidates for playing such a role, yet th
22 icronutrient chromium picolinate (CrP), with long-standing cardiovascular benefits, inhibits TSP-1 ex
23 mation - visual search in short - has been a long-standing central topic in vision science.
24 standing prebiotic nucleotide synthesis is a long standing challenge thought to be essential to eluci
25 rect arylation of cyclopentanones has been a long-standing challenge because of competitive self-aldo
26 transfer between a material and protein is a long-standing challenge confronting applications in bioe
27 g-term delivery of growth factors has been a long-standing challenge for stem cell-based tissue engin
28 lls within their native spatial context is a long-standing challenge in biology.
29 utes to many important molecules and solve a long-standing challenge in chemistry.
30  Global searching for reaction pathways is a long-standing challenge in computational chemistry and b
31                      This method overcomes a long-standing challenge in distinguishing rotational mot
32 eaction and its direct characterization is a long-standing challenge in physical chemistry.
33 nator mode to a sub-thermal state has been a long-standing challenge in physics.
34 esence of multiple reactive sites has been a long-standing challenge in the field.
35                                            A long-standing challenge is thus to observe individual gr
36                                            A long-standing challenge of untargeted metabolomic profil
37 mit Texas hold'em, the leading benchmark and long-standing challenge problem in imperfect-information
38  groups (for example, natural products) is a long-standing challenge that has been addressed using ca
39                                   A critical long-standing challenge though is that key features of t
40                                It has been a long-standing challenge to increase the melted zone (MZ)
41                                It has been a long-standing challenge to produce air-stable few- or mo
42  heavy fermion compounds and has presented a long-standing challenge to transport theory.
43 oper interpretation of field potentials is a long-standing challenge.
44 s needed for proper embryogenesis has been a long-standing challenge.
45 ia an iron carbene intermediate represents a long-standing challenge.
46 unsaturated lipid isomers, however, remain a long-standing challenge.
47 anslational motions in the z-axis has been a long-standing challenge.
48 ng identification of drivers of synchrony, a long-standing challenge.
49 etal catalysts is crucial to addressing this long-standing challenge.
50 has made significant progress toward solving long-standing challenges facing the US health care syste
51 droxyl groups in carbohydrates is one of the long-standing challenges in chemistry.
52 fluids and microscopic defects is one of the long-standing challenges in understanding a broad range
53 itude lower than either constituent, defying long-standing composite bounds.
54 ion and analyses are important and have been long-standing computational problems in bioinformatics.
55 s of an entire protein, thus challenging the long-standing concept of overdamped global protein dynam
56                           Drug toxicity is a long-standing concern of modern medicine.
57                        Our results resolve a long-standing controversial hypothesis and indicate that
58                       These findings resolve long-standing controversies regarding elastin structure
59 lights recent work that sheds light on these long-standing controversies.
60 f vertebrate gills has been the subject of a long-standing controversy [2-8].
61      The current study serves to resolve the long-standing controversy about the active sites for SCR
62                        Our results resolve a long-standing controversy and explain how cells use cent
63                                            A long-standing controversy is whether a NOS exists within
64               Applying this principle to the long-standing controversy of calmodulin binding to ion c
65            Moreover, our results resolve the long-standing controversy over the origin of the incomme
66                      This finding resolves a long-standing controversy regarding the role of glial ce
67 yloidogenic polypeptide that eliminates this long-standing controversy.
68 one variant H2A.Z on transcription remains a long-standing conundrum.
69 tion affected by congenital, prelingual, and long standing deafness?
70 d challenge in evolutionary biology, despite long-standing debate about the relative importance of na
71                                     First, a long-standing debate about the significance of aggressio
72 ividuals make decisions has been a matter of long-standing debate among economists and researchers in
73  structure and interactions, thus settling a long-standing debate as to whether or not the claim of u
74 of both naive and effector cells, fuelling a long-standing debate centred on whether memory T cells d
75                                            A long-standing debate concerns how functional responses a
76                               There has been long-standing debate on how free charges are generated i
77                      This work addresses the long-standing debate over fractal models of packing stru
78                           This clarifies the long-standing debate over the viability of metal confine
79 ommon error signal, which cannot resolve the long-standing debate regarding whether both eyes are inn
80           These results strongly support the long-standing debate that if the coarsening of Ptnano fr
81 t, and they help to bring resolution to this long-standing debate.
82  they regulate their own transportation is a long-standing debate.
83                                   One of the long standing debates in actinide chemistry is the level
84                                              Long-standing debates exist over the timing and mechanis
85 plain features such as the DUPAL anomaly and long-standing differences between Indian and Pacific Oce
86   Our analysis methodology, which resolves a long-standing disagreement on defect structures and the
87                          The results resolve long-standing discrepancies between structural and funct
88                              To address this long-standing discrepancy, we measured hippocampal activ
89                                Patients with long-standing disease need regular ophthalmic checkups b
90                                 However, the long-standing dogma that reticulate evolutionary process
91                Hydrogen sulfide removal is a long-standing economic and environmental challenge faced
92 e for neuroscientific discoveries in shaping long-standing economic views of decision-making.
93  Trapping or cooling molecules has rallied a long-standing effort for its impact in exploring new fro
94 dentified in all domains of life, there is a long-standing effort to search in prokaryotes and eukary
95      These results provide insights into the long-standing effort to understand the structural attrib
96                                      It is a long-standing enigma how glycogen storage disease (GSD)
97 termediate in Africa and Asia - represents a long-standing enigma in ecology.
98 or to the end of their natural lifespan is a long-standing evolutionary puzzle [1-4].
99 (ARDS) is undefined in neonates, despite the long-standing existing formal recognition of ARDS syndro
100 n and measurement of polymer chains remain a long-standing fundamental issue in conjugated polymers a
101 encies in primates and carnivores, filling a long-standing gap in mammalian bioacoustics and providin
102                        Our study addresses a long-standing gap in the repertoire of human prion disea
103   The identification of this enzyme closes a long-standing gap in understanding of the riboflavin bio
104 olid-state thermoelectric devices has been a long standing goal.
105 ity-dependent plant population dynamics is a long-standing goal in ecology.
106 f adaptive diversity within populations is a long-standing goal in evolutionary biology, with importa
107 zation of the mouse genes, hence, has been a long-standing goal in mammalian and human genetics.
108 es and selectivities of natural enzymes is a long-standing goal in protein chemistry.
109 ng of the fetal gamma-globin gene has been a long-standing goal in the treatment of sickle cell disea
110                    Our approach achieves the long-standing goal of a tight feedback cycle between com
111                                            A long-standing goal of artificial intelligence is an algo
112                                            A long-standing goal of DNA nanotechnology has been to ass
113 tunability of lyotropic materials has been a long-standing goal of liquid crystal research.
114                                            A long-standing goal of neuroscience has been to understan
115                                            A long-standing goal of psychopathology research is to dev
116  to measurable behavioral changes has been a long-standing goal of systems neuroscience.
117                                   One of the long-standing goals of the DNA nanotechnology field has
118  bridge this gap using data from a large and long-standing HIV-1 prospective cohort, in Uganda.
119 mmunogens of practical value for solving the long-standing HIV-1 vaccine problem.
120 tiology of HFpEF is most commonly related to long-standing hypertension and atherosclerosis, a signif
121                          Skeletal changes of long-standing hypoparathyroidism are irreversible.
122 pine revealed spondylarthropathic changes of long-standing hypoparathyroidism.
123 ur findings add considerable weight to three long-standing hypotheses according to which the sex disp
124                               We tested this long-standing hypothesis by assessing geographic covaria
125                                 We test this long-standing hypothesis by depleting miR-200, a family
126                                            A long-standing hypothesis is that neurons fire less durin
127                                            A long-standing hypothesis maintains that the high-(3)He/(
128 s of a pathogen with Siglecs and support the long-standing hypothesis that activating counterparts of
129             Protein mutagenesis supports the long-standing hypothesis that four conserved GXQ amino a
130               Our results do not support the long-standing hypothesis that interspecific territoriali
131     We review recent findings supporting the long-standing hypothesis that the waves of TE invasions
132 pirical experiment with snails supports this long-standing hypothesis.
133  debris volume, revealing the origins of the long-standing hypothesized correlation between the wear
134                                              Long standing IBD predisposes individuals to colitis-ass
135                                            A long-standing idea is that fixation depends on soil nutr
136     Conservation across phyla emphasizes the long-standing importance of the Psp system in prokaryote
137 data have begun to challenge the notion that long-standing in vivo observations are driven solely by
138                                          The long-standing inability to visualize connections between
139                              Addressing this long-standing incongruity, we used calorimetry and magne
140 esents a notable departure from the previous long-standing increases in the number of postdoctorates
141                         Accordingly, decades-long standing inefficiencies in targeted nuclear gene ed
142 d to heterosexual males; recent, compared to long-standing, infection (OR, 2.72 [95% CI, 1.64-4.52]);
143 tion and stabilization mechanisms has been a long standing interest in the material field.
144                         Nanoparticles are of long-standing interest for the treatment of neurological
145 ty in neural systems, which is a question of long-standing interest in computational neuroscience.
146            However, such correlations are of long-standing interest in fields including ecology.
147                                      Despite long-standing interest in the association of psychiatric
148                               There has been long-standing interest in the role of bacterial communit
149 s inflammatory bowel disease, there has been long-standing interest in understanding the molecular ba
150                                    There are long-standing interests in the potential benefits of vit
151 her sampled Iranian group, consistent with a long-standing isolation of Zoroastrians from outside gro
152 (MDs) form in a GeSi/Si(001) film has been a long standing issue.
153                                          One long-standing issue in directed C-H functionalization is
154 n, or direct physical processes represents a long-standing issue in ecology, with important consequen
155  use of this method in Drosophila to solve a long-standing issue in patterning of the embryonic centr
156                                            A long-standing issue in topological insulator research ha
157         However, this has been hampered by a long-standing issue in transcriptional profiling of diss
158 or strongly correlated oxides, it has been a long-standing issue regarding the role of the chemical o
159 sistance to particle irradiation damage is a long-standing issue.
160 zheimer's disease (AD) associated with their long-standing kidney disease and/or neurotoxic immunosup
161 uired light exposure by >98% and resolving a long-standing limitation in optogenetic inhibition.
162                                   However, a long-standing limitation of SSF has been too low ethanol
163  incorporating this modified model reduces a long-standing mismatch between the modeled and observed
164 sents a substantial advance in resolving the long-standing model data conflict of Miocene Antarctic i
165  budding yeast Saccharomyces cerevisiae is a long-standing model for the three-dimensional organizati
166 us and lack apparent sequence specificity, a long-standing model is that targeting occurs via protein
167 id binding behaviors of Akt, contrary to the long-standing model of Akt regulation.
168 l network manipulation promises to unravel a long-standing mystery in neuroscience: how does microcir
169                  As a result, the key to the long-standing mystery of how trees maintain phloem trans
170 ure and function of A6 in order to solve the long-standing mystery of poxvirus membrane biogenesis.
171 In this issue of Cell, Wenzel et al. solve a long-standing mystery regarding how damage to cell membr
172 dependent sex determination (TSD) has been a long-standing mystery; in particular, the thermosensitiv
173 e transport, and monkeys with diet-dependent long-standing obesity/T2DM.
174 e, offering a novel basis to account for the long-standing observation of favorable prognosis associa
175 tudies (GWAS) and pathway analyses supported long-standing observations of an association between imm
176                         Here, we address the long-standing open question of whether every pure bipart
177                                            A long-standing paradigm assumes that the chemical and iso
178                      Modular redefinition: A long-standing paradigm in modular polyketide synthase en
179                                            A long-standing paradigm posits that hypothalamic corticot
180 ases, it is time to revisit the existing and long-standing paradigm supporting aspirin use for second
181 parental brain may contribute to solving the long-standing paradox of self-sought hedonic exposure to
182 OS process and provide new insights into the long-standing paradox of the duration of the induced mag
183 omic inbreeding coefficients may resolve the long-standing paucity of data on inbreeding depression i
184 olation and occlusion in patients undergoing long-standing persistent AF ablation.
185 edian AF duration was 51 months, and 78% had long-standing persistent AF.
186 al fibrillation (AF) duration and persistent/long-standing persistent AF.
187           METHODS AND Thirteen patients with long-standing persistent atrial fibrillation (duration,
188 drive persistent atrial fibrillation (PeAF), long-standing persistent atrial fibrillation (LPeAF), or
189          Rotor domains appropriately explain long-standing persistent atrial fibrillation physiology
190 AF trial (Ablation at St. Georg Hospital for Long-Standing Persistent Atrial Fibrillation), we sought
191              In patients with persistent and long-standing persistent atrial fibrillation, no signifi
192                                     In human long-standing persistent atrial fibrillation, rotors pot
193 , in patients with symptomatic persistent or long-standing persistent atrial fibrillation, the outcom
194 ial fibrillation (paroxysmal, persistent, or long-standing persistent), patient comorbidities, genera
195 47 mm, Type of AF [paroxysmal, persistent or long-standing persistent], and ER-AF = early recurrent A
196 s of crystal nucleation and growth, and that long-standing physical concepts of nucleation can descri
197                          The most common and long-standing polymer modification is the attachment of
198 ut their complex chemical structures present long-standing practical challenges to their synthesis.
199 ors of transfer efficacy, substantiating the long-standing practice of manual curation in comparative
200                  These data substantiate the long-standing presumption that anatomic differences in u
201                We present a solution to this long-standing problem by applying two complementary pass
202                         Phase retrieval is a long-standing problem in imaging when only the intensity
203                                            A long-standing problem in modeling of shock response of m
204 electrophiles (Suzuki-Miyaura reaction) is a long-standing problem in synthesis, but progress has bee
205 t and the peak near-surface wind speed, is a long-standing problem in tropical meteorology that has b
206 lass nanopillars to anchor islets, solving a long-standing problem of keeping tissue-scale objects im
207 THU-15 has been successful at overcoming the long-standing problem of organic-templated extra-large-c
208                                            A long-standing problem plaguing the field of transition m
209 t, which provides an efficient solution to a long-standing problem.
210 lar mechanism of this recognition has been a long-standing problem.
211  that may provide a general solution to this long-standing problem.
212 ially powerful new approach to confront this long-standing problem.
213                                              Long-standing problems associated with long-ranged elect
214 on of comets to inner-planet atmospheres are long-standing problems.
215 provides important neural evidence about the long-standing proposal that self-consciousness is linked
216  point to a role for neuroscience in shaping long-standing psychological theories in decision science
217 oroughly studied actinide material, remain a long standing puzzle, a result of strong coupling betwee
218 re, a genomic screening strategy solves this long-standing puzzle and identifies NACHO, a transmembra
219                            This explains the long-standing puzzle as to why the neutralization of the
220                                            A long-standing puzzle has been why the AU dincucleotide a
221                                         This long-standing puzzle is usually explained by charge inho
222                                            A long-standing puzzle remains unsolved: why the Au surfac
223 d its stringent host specificity have been a long-standing puzzle.
224           This allowed us to resolve several long-standing puzzles about the atomistic OER mechanism.
225 ood model that provides a unified account of long-standing puzzles in 3D vision at the physiological
226 t also represent molecular-level insights on long-standing puzzles in nanochemistry, including LaMer
227                                            A long standing question in organic electronics concerns t
228                       Our results answer the long standing question of the physical mechanisms drivin
229                     Thus, we have answered a long-standing question about the nature of CsoS2 in this
230                           Our data resolve a long-standing question about the role of DG in memory an
231                        Our results resolve a long-standing question and suggest that many individual
232                                It has been a long-standing question as to whether the activation of N
233                         This work resolves a long-standing question in bioenergetics, and renders a c
234                                            A long-standing question in biology is how a group of prim
235                                            A long-standing question in cell biology is how endocytic
236                                            A long-standing question in collective cell migration has
237 ions traverse rugged fitness landscapes is a long-standing question in evolutionary biology.
238                                            A long-standing question in evolutionary developmental bio
239 hicle-related emissions on health has been a long-standing question in human health sciences; however
240                                            A long-standing question in neurodevelopment is how neuron
241 organic donor-acceptor interfaces has been a long-standing question in the organic photovoltaics comm
242                                            A long-standing question in the physics of solids has been
243                                            A long-standing question is whether neoblasts directly sen
244                                            A long-standing question of human immunodeficiency virus (
245 as C/EBPbeta.Significance: In addressing the long-standing question of the difference between normal
246 ols, the field is now prepared to tackle the long-standing question of the evolutionary basis of micr
247                                 However, the long-standing question of whether a cloned animal underg
248 em and, through real-time imaging, address a long-standing question of whether the solitons in trains
249                     This study addresses the long-standing question of which early molecular changes
250 well as lay the foundation for resolving the long-standing question regarding the pathogenesis mechan
251          How bats mitigate interference is a long-standing question that has both ecological and tech
252 dosomes in receptor signal transduction is a long-standing question, which remains largely unanswered
253 ute functional diversity to brain cells is a long-standing question.
254 n to mediate leprosy pathogenesis has been a long-standing question.
255 ear and what drives human sexual cycles is a long-standing question.
256 ysialic acid (polySia) in myelin repair is a long-standing question.
257 dented and exciting opportunities to address long standing questions in biomedical research.
258  developments offer opportunities to address long-standing questions about the establishment of effec
259 of this unique developmental process answers long-standing questions about the evolutionary origin of
260 ers, physicists, and mathematicians to solve long-standing questions about the way in which repair en
261                              There have been long-standing questions about whether wood used by Strad
262 chromatin pathways, offering explanations to long-standing questions and presenting new challenges.
263 a-null sperm now make it possible to resolve long-standing questions in fertilization biology, and to
264 nder biologically relevant conditions-answer long-standing questions in membrane biology and illustra
265                                          Two long-standing questions in neuroscience are how sleep pr
266                                However, many long-standing questions in plant biology remain unanswer
267          They have facilitated studying many long-standing questions regarding growth, chemotaxis and
268                                    These are long-standing questions that have proven difficult to an
269 s helped in resolving a number of difficult, long-standing questions, constructing appropriate datase
270                                              Long-standing racial differences in US life expectancy s
271                                  Despite the long-standing recognition of the prominence of CAFs in P
272                                  Despite the long-standing recognition of this phenomenon, an empiric
273 bases to identify immigrant (since 1985) and long-standing resident cohorts.
274 ive care for recent immigrants compared with long-standing residents varied according to recent immig
275 nce, and causes of death were similar, while long-standing residents were older than immigrant decede
276 hium/sodium metals, and hence eliminates the long-standing safety issue.
277                                            A long-standing scientific challenge in the field of alcoh
278 at extreme pressure conditions, represents a long-standing scientific challenge.
279 f newly available data sources in addressing long-standing scientific questions.
280 ed one of the autoantibodies associated with long-standing SS, which are included in the diagnostic c
281 lso has great implications on overcoming the long-standing strength-ductility tradeoff of metallic ma
282 ne surfaces is important for deciphering the long-standing structural enigma in self-assembled monola
283 a new MALS methodology that has overcome the long-standing, stubborn barrier to microliter-scale peak
284 tissue remodeling that was essential for the long-standing success of the implants.
285  neurons provides a neuronal context for the long-standing "synergy hypothesis" of sodium appetite re
286 ol over these structural parameters presents long-standing synthetic challenges.
287 al syntheses of (-)-2(S)-cathafoline and the long-standing target (+)-strictamine.
288 gnificantly from human FAS pathways and is a long-standing target for antibiotic development against
289 diates in redox catalysis and have thus been long-standing targets of synthetic chemistry.
290 n networks of interacting species has been a long-standing theoretical puzzle for ecologists.
291                                    Bleaney's long-standing theory of magnetic anisotropy has been emp
292 escribed for the first time, which overrides long-standing trifluoromethyl anion-based theory.
293  to improve glycaemic control in adults with long-standing type 1 diabetes as suggested by current gu
294 so complicated by stage 4 renal failure from long-standing type II diabetes, hypertension, iron defic
295 TCR initiation remains unclear, with several long-standing unanswered questions.
296 ntries on five continents, to elucidate this long-standing unresolved issue.
297 ed for atomic electron tomography to address long-standing unresolved problems in the physical scienc
298                                          The long-standing view is that ecological interactions such
299                              Contrary to the long-standing view of stigmarian systems, where shoot-li
300                                  Contrary to long-standing views, men and women with the APOE epsilon

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