ライフサイエンスコーパス: longstanding

1 Conversely, in the presence of longstanding AF or atrioventricular block, uncoupled nit

2 f patients with IgG4-RD are reported to have longstanding allergies, peripheral blood eosinophilia, a

3 ract with different vesicle populations is a longstanding and challenging problem with implications f

4 phenols under mild reaction conditions is a longstanding and formidable challenge in organic chemist

5 recise nature of osteoclast progenitors is a longstanding and important question.

6 There are longstanding and ongoing controversies about the abiotic

7 tients from the Swiss Barmelweid cohort with longstanding and severe COPD and 342 patients from the S

8 The community music training was a longstanding and successful program that provides free m

9 an Leuven et al. illuminate how a stable and longstanding animal-microbe mutualism increased its inte

10 ons and radiographic damage in patients with longstanding ankylosing spondylitis (AS).

11 rasite isolates from areas with a history of longstanding antifolate use.

12 Despite the longstanding appreciation of communication between the n

13 al forebrain and conclude by reiterating the longstanding argument that the transitional nature of su

14 ons and radiographic damage in patients with longstanding AS.

15 ssue of Neuron, Vervaeke et al. broaden this longstanding association.

16 This discrepancy calls into question the longstanding assumption of Black and Ebony interaction.

17 vidence accumulation process challenges this longstanding assumption.

18 been isolated from cognitive science by two longstanding assumptions: that it depends on a set of sp

19 C57BL/6 (H-2) donors were transplanted onto longstanding B10.BR recipients of K skin to test for lin

20 rticles are specifically designed to address longstanding barriers in siRNA delivery such as cellular

21 ndings provide a neural mechanism to explain longstanding behavioural observations, including the pre

22 There has been a longstanding belief that vertebrates do not produce chit

23 Silver-containing mordenite (MOR) is a longstanding benchmark for iodine capture; however, the

24 A longstanding but unfulfilled goal has been to develop po

25 Kinesin 5 is a longstanding candidate for a molecular motor that might

26 onance (NMR) to nanoscale samples has been a longstanding challenge because of the insensitivity of c

27 idization chain reaction (HCR) overcome this longstanding challenge by operating independently within

28 into colloidal nanocrystals (NCs) has been a longstanding challenge for nanomaterial research.

29 tissues respond to biophysical stimuli is a longstanding challenge in biology and tissue engineering

30 n and organism level during development is a longstanding challenge in biology, but recent molecular-

31 ctional complexity of organisms evolves is a longstanding challenge in biology.

32 ic lineage among a myriad of candidates is a longstanding challenge in developmental biology and an e

33 gic approach to male contraception remains a longstanding challenge in medicine.

34 ap states in semiconductor nanocrystals is a longstanding challenge in nanoscience.

35 symmetric alkylation of acyclic ketones is a longstanding challenge in organic synthesis.

36 A longstanding challenge in studies of neurodegenerative d

37 Thus, a longstanding challenge in the field of biologically medi

38 n dioxide to value-added chemical fuels is a longstanding challenge in the fields of catalysis, energ

39 Faculty diversity is a longstanding challenge in the US.

40 sponse properties in the thalamus has been a longstanding challenge in visual neuroscience.

41 The longstanding challenge posed by the complex diterpene vi

42 from the interconnections of its parts is a longstanding challenge that has concerned many scientist

43 There is a longstanding challenge to disperse metal nanoparticles u

44 lectron affinities (EAs) of lanthanides is a longstanding challenge to experimentalists.

45 expensive, and scalable method overcomes the longstanding challenge to produce bulk polymer-metal nan

46 connection to biological catalysis remains a longstanding challenge, in part due to the paucity of in

47 The chemical synthesis of insulin has been a longstanding challenge, mainly because of the notorious

48 nthetic CO2-fixing enzyme Rubisco has been a longstanding challenge.

49 rphous cross-linked polymeric materials is a longstanding challenge.

50 f electronically unbiased alkenes has been a longstanding challenge.

51 ng their intriguing physical properties is a longstanding challenge.

52 and underlying cellular dynamics has been a longstanding challenge.

53 e a scalable platform for overcoming several longstanding challenges in applied nonlinear and quantum

54 Longstanding challenges in resolving this functional dic

55 on with radiation therapy (RT), leads to the longstanding clearance of tumor in T- and B-cell lymphom

56 Despite its longstanding clinical use and efficacy, the molecular me

57 r (HAS) and L'Hopital Bon Sauveur (HBS) have longstanding commitments to provide equitable surgical c

58 Spatial cyberinfrastructure seeks to resolve longstanding complex problems of handling and analyzing

59 s thus confirm the hallmark predictions of a longstanding computational model of hippocampal memory p

60 The longstanding concept that corneal epithelial stem cells

61 Here, we revisit the longstanding concept that some of the gene products enco

62 m ongoing microRNA research that is altering longstanding concepts of the mechanisms for, and consequ

63 rough provides an opportunity to re-evaluate longstanding concepts regarding the cause and natural hi

64 There is a longstanding concern about the accuracy of surrogate con

65 A longstanding concern is that reporter assays are mainly

66 est in lncRNAs is deeply rooted in biology's longstanding concern with the evolution and function of

67 There are longstanding concerns that target-oriented and performan

68 portunities for translation realized through longstanding connection with the community; integration

69 r-selected regions, allowing, in addition to longstanding consed capabilities such as assembly editin

70 Patients with longstanding, constant strabismus lacked normal facilita

71 chnological advances, progress has clarified longstanding controversies in the field.

72 Longstanding controversies such as the timing of surgery

73 mised trials hinder clinical management, and longstanding controversies such as use of antibiotic pro

74 o clarify the function of BB0647 and resolve longstanding controversies.

75 The longstanding controversy on the nature of the hydrogen b

76 Our results resolve a longstanding controversy regarding the origin of the ST5

77 A longstanding conundrum has been how yeast survives witho

78 A longstanding convention divides CPNs into two groups tha

79 Longstanding corneal edema can lead to anterior stromal

80 poisons doxorubicin and etoposide constitute longstanding cornerstones of chemotherapy.

81 The three hemianopic patients with longstanding damage to either V1 or LGN showed lateralit

82 However, longstanding data also indicate IgG and complement depos

83 naptic facilitation, these results resolve a longstanding debate about a widespread form of short-ter

84 tiple tubulin isoforms, and there has been a longstanding debate as to whether the isoforms are redun

85 characteristic b2 fragment ion, a subject of longstanding debate in MS-based proteomics.

86 opy experiments also provide resolution of a longstanding debate in the literature regarding the spec

87 A longstanding debate in the protein-folding field is whet

88 However, there is a longstanding debate over the influence of spines on the

89 psid reptile skulls could shed light on this longstanding debate.

90 We use this quantum interface to resolve two longstanding debates about the anomalous spectroscopic g

91 s from this ceramic record can contribute to longstanding debates concerning the origins of farming.

92 direction of inquiry for resolving similarly longstanding debates in cuprate superconductors and othe

93 The fact that longstanding debates in the job strain literature were r

94 effects on health, including new analysis of longstanding debates, and identify opportunities for eff

95 h metallic nanoslits has been the subject of longstanding debates.

96 Our study changes the longstanding definition of how p53 is inactivated in ade

97 uration) and 1.22 (0.83-1.80) for those with longstanding diabetes (> 2 years).

98 Longstanding diabetes might increase the risk of acute r

99 A longstanding dichotomy in cognitive psychology and neuro

100 nowledge are integrated remain unclear, with longstanding disagreement concerning whether integration

101 Patients with UC with longstanding disease and in remission do not have more I

102 ymptoms in patients with UC in remission and longstanding disease in comparison to control subjects.

103 e prevalence of IBS in patients with UC with longstanding disease is not known.

104 sted in a small portion of the patients with longstanding disease.

105 esolve slowly, particularly in patients with longstanding disease.

106 occur in JIA in association with severe and longstanding disease.

107 ocative argument even more convincing is the longstanding, documented safety of intravenous estrogen

108 The longstanding dogma that cholesterol (chol) autoxidation

109 This segregation shows Latin America's longstanding economic and social inequality, cemented by

110 Longstanding efforts to develop novel KRAS inhibitors ha

111 A longstanding endeavor to define the genetic lesions that

112 Here we address two longstanding enigmatic aspects of SOS mutagenesis, the m

113 mice, providing a possible explanation for a longstanding enigmatic association between immunodeficie

114 s may underlie the molecular explanation for longstanding enigmatic observations on inconsistent rapa

115 igures of severe asthma are lacking, whereas longstanding estimates vary between 5% and 10% of all as

116 or inadequate legal demands, and to reassess longstanding ethical certainties in the strictest view o

117 Longstanding evidence supports PKC-stimulated DAT traffi

118 Here we review longstanding evidence that the striatum and its cortical

119 ion, and we speculate that it derives from a longstanding evolutionary origin.

120 cusing on mate-choice mechanisms may clarify longstanding evolutionary puzzles in sexual selection an

121 For most topics, a longstanding expert was paired with an excellent contemp

122 xisting knowledge about NK cells is taken as longstanding fact, it may be surprising to immunologists

123 bnormal cardiac output" for a patient with a longstanding family history of heart disease, "decreased

124 The study aims to survey longstanding funduscopic and functional outcomes of age-

125 This discovery fills a longstanding gap in our understanding of a major polymer

126 of intense DNA methylation change, ensuring longstanding genome stability.

127 uble-stranded DNA (dsDNA) regions has been a longstanding goal as evidenced by the emergence of tripl

128 d and mismatched DNA/RNA targets, has been a longstanding goal due to potential applications as degen

129 In particular, a longstanding goal has been to understand how the evoluti

130 ber of photons and harness their energy is a longstanding goal in artificial photosynthesis.

131 A longstanding goal in cellular mechanobiology has been to

132 lar proteins via pharmacological agents is a longstanding goal in chemical biology.

133 A longstanding goal in neuroscience is to understand how s

134 gen peroxide levels as a function of time, a longstanding goal in the field of redox signaling.

135 r structures, has now opened the door to the longstanding goal of precisely controlling molecular int

136 A longstanding goal of synthetic biology has been the prog

137 genes for FVIII and FIX some 30 years ago, a longstanding goal of the field has been development of s

138 hemical properties of condensed systems is a longstanding goal of theoretical (quantum) chemistry.

139 cally relevant responses against cancer is a longstanding goal.

140 modulators of individual isozymes has been a longstanding goal.

141 e that men with lower amygdala volume have a longstanding history of aggression and psychopathic feat

142 rder as a psychiatric/medical disorder has a longstanding history of ethical and social challenges th

143 A man in his 70s with a longstanding history of genetically confirmed HCM presen

144 We present three cases with a longstanding history of sarcoidosis that have been addit

145 Longstanding HIV infection acquired when the immune syst

146 Among adolescents with longstanding HIV-induced immunosuppression and with high

147 roster of MS susceptibility genes beyond the longstanding human leukocyte antigen (HLA) association i

148 rovide manipulative experimental support for longstanding hypotheses in psychology, that genetic vari

149 One longstanding hypothesis argues that sex is beneficial be

150 A longstanding hypothesis is that matrix TC systems are cr

151 gh underlying mechanisms remain unsettled, a longstanding hypothesis proposes that feedback is due to

152 These results are consistent with the longstanding hypothesis that circuits involving the basa

153 Here, we test the longstanding hypothesis that disrupted MSCI might contri

154 However, the framework retains the longstanding hypothesis that motor activity is engaged o

155 Specifically, it experimentally confirms the longstanding hypothesis that PDF is a direct modulator o

156 A longstanding idea about syntactic processing is that it

157 Adjustment for longstanding illness and major cardiometabolic risk fact

158 It was associated with poor health, longstanding illness or disability, and treatment for me

159 c TCRs de novo from a random repertoire is a longstanding immunological question.

160 ons tailored to solve particular problems of longstanding importance to our species, the human brain

161 neurons in the CNS has been hampered by the longstanding inability to reliably detect somal immunore

162 ar complications despite having a history of longstanding inadequate glycemic control had higher expr

163 Despite longstanding infant vaccination programs in low- and mid

164 Three recipients cleared longstanding infection after intervention with ribavirin

165 A longstanding interest and challenge has been to make suc

166 sformation of triclosan has been a matter of longstanding interest due to both its prevalence in the

167 e two simple building blocks, there has been longstanding interest in engineering the incorporation o

168 ian and ecosystem metabolism, there has been longstanding interest in measuring their metabolite leve

169 The American Board of Ophthalmology has a longstanding interest in patient safety, and in 2015, te

170 Accordingly, there is a longstanding interest in the development of new opioid a

171 Despite a longstanding interest in the differences between the nuc

172 very of the default mode network reignited a longstanding interest in the significance of the brain's

173 Despite this longstanding interest, the neural representations of gen

174 Despite longstanding interest, the neural structures that proces

175 Our nation's longstanding investment in federally funded cancer resea

176 ain dynamics in ferroic materials has been a longstanding issue because of its relevance to many syst

177 We resolve this longstanding issue by first determining the scaling of e

178 The longstanding issue of the origin of the negative Hall co

179 reagent provides for the resolution of some longstanding issues in T helper cell development.

180 However, the TSR remains a longstanding life-history puzzle for which no dominant d

181 A longstanding limitation for using chemical compounds in

182 PARTICIPANT: A 49-year-old man with longstanding, medication-resistant, upbeat nystagmus res

183 o the sexual reproduction of plants and is a longstanding model for cellular tip growth.

184 an Ciona consists of only 40 cells, and is a longstanding model for studying organogenesis in a small

185 Spin glasses are a longstanding model for the sluggish dynamics that appear

186 A longstanding model is that activated Bak and Bax insert

187 d behaviour, and are allowing novel tests of longstanding models about the functions of brain oscilla

188 These results provide empirical support for longstanding models of sex chromosome catalysis, and sug

189 provides an alternative explanation for this longstanding mystery about generation of concurrent soun

190 Cloning the sigma2 receptor resolves a longstanding mystery and will enable therapeutic targeti

191 ovide will accelerate our understanding of a longstanding mystery in EBV biology and guide efforts to

192 alling and response in laticifers resolves a longstanding mystery of ethylene stimulation in rubber p

193 RNA, first observed in the 1970s, has been a longstanding mystery.

194 enation but whose molecular basis has been a longstanding mystery.

195 tor (VEGF) therapy, indicating a more mature longstanding neovascular complex resistant to anti-VEGF

196 s poor psychosocial outcome is the result of longstanding neurological changes, whereas for others it

197 aca sativa), in its native Europe and in its longstanding nonindigenous range in the midwestern Unite

198 The data presented here challenge this longstanding notion and argue instead for segregated ope

199 in human heart, these findings challenge the longstanding notion that autoimmune targeting of MyHC is

200 neuroimaging findings have greatly modified longstanding notions regarding the pathophysiology of am

201 re outer membrane proteins (OMPs) has been a longstanding objective of syphilis researchers.

202 findings also suggest an explanation for the longstanding observation that M. tuberculosis initiates

203 depolarization of these solid solutions is a longstanding obstacle for their practical applications.

204 In this article we solve this longstanding open problem by providing the first exact a

205 exity evolves in biological populations is a longstanding open question.

206 ME seems to be a common complication of longstanding OT in the adult.

207 This work helps to refine a longstanding paradigm indicating stress granules are ine

208 This longstanding paradigm is being challenged by two papers

209 expression in GC progression, challenge this longstanding paradigm.

210 We apply this theory to explain a longstanding paradox in biology and medicine: the evolut

211 election may provide an explanation for this longstanding paradox of population genetics.

212 Longstanding persistent (LSP) atrial fibrillation (AF) i

213 AF (OR, 1.01; 95% CI, 0.63-1.64; P=0.96) or longstanding persistent AF (OR, 0.84; 95% CI, 0.24-2.96;

214 atrial electrogram ablation (persistent and longstanding persistent AF) were the end points at the t

215 edure Outcome in Patients With Persistent or Longstanding Persistent Atrial Fibrillation Undergoing C

216 mptomatic AF (61% paroxysmal, 39% persistent/longstanding persistent) to undergo either SRI or WAI.

217 th AF (paroxysmal: n=3; persistent: n=4; and longstanding persistent: n=3) and 4 patients without a h

218 However, there is a longstanding perspective, and ample functional magnetic

219 presence of PEG-specific antibodies may be a longstanding phenomenon.

220 rolling chemical reactivity using light is a longstanding practice within organic chemistry, yet litt

221 determines the length of S phase has been a longstanding problem in developmental biology.

222 of its brevity and also because it solves a longstanding problem in the field of natural product syn

223 A longstanding problem in the social, biological, and comp

224 vides a critical first step toward solving a longstanding problem in the successful heterologous expr

225 However, a longstanding problem is that the different abstractions

226 r differential perturbations may address the longstanding problem of discriminating direct and indire

227 say that can be broadly applied, solving the longstanding problem of how to rapidly determine the cel

228 findings provide important insights into the longstanding problem of the position of the root of the

229 This method, which addresses a longstanding problem, is useful for assessing how geneti

230 rprising new insights into well established, longstanding problems.

231 This is consistent with the longstanding proposal that condensin provides a bias in

232 the performance of JDY, a woman with severe, longstanding proprioceptive deficits from a sensory peri

233 nation rate declines as patients progress to longstanding PsAF, underscoring the importance of early

234 tropin-releasing hormone (GnRH) represents a longstanding puzzle about extracellular signal decoding

235 Herein, we resolved this longstanding puzzle by combining a detailed product anal

236 gin in Waldenstrom macroglobulinemia (WM), a longstanding puzzle due to conflicting and incomplete da

237 It is a longstanding puzzle why non-coding variants in the compl

238 utes to early auditory processing has been a longstanding puzzle.

239 ir widely varying accretion rates-has been a longstanding puzzle.

240 t during enzymatic turnover, thereby solving longstanding puzzles.

241 believe that these findings resolve a major, longstanding question about morphogen gradient formation

242 The results clarify a longstanding question about the mechanism of cathepsin A

243 Here, we answer this longstanding question by using transgenic Hydra expressi

244 A longstanding question concerns the structure of the C-te

245 A longstanding question in cellular neuroscience is how mi

246 A longstanding question in centromere biology has been the

247 eurons relate to tuned neural responses is a longstanding question in systems neuroscience.

248 ogether, the results of this study address a longstanding question in the field and suggest that acti

249 One longstanding question is how early in the visual system

250 A longstanding question is how Ptc inhibits Smo and how su

251 chanism provides important insights into the longstanding question of how the receptor transduces sig

252 The structures address the longstanding question of how UGM binds NAD(P)H and provi

253 e sGC heme domain reported here resolves the longstanding question of where stimulators bind and prov

254 al equivalent of nsp1, thereby answering the longstanding question of whether lack of nsp1 in gammaco

255 a formation, thus providing insight into the longstanding question of why nerves are required for axo

256 Here, we address a longstanding question regarding the role of DksA in Delt

257 t motivates animal cells to intercalate is a longstanding question that is fundamental to morphogenes

258 Here, we resolve this longstanding question using a mouse model null for the g

259 e regulation of complex behaviors has been a longstanding question.

260 sian monsoon on varying timescales remains a longstanding question.

261 Many longstanding questions about dynamics of virus-cell inte

262 ologies provide new opportunities to address longstanding questions about habitat adaptation in micro

263 fant baboons with B. pertussis, are enabling longstanding questions about pertussis pathogenesis to b

264 To answer longstanding questions about the origin of these complex

265 lize toxic oligomeric complexes could answer longstanding questions about the pathogenesis of other p

266 f mouse visual cortex as a system to address longstanding questions of visual neuroscience and cortic

267 The data reported here address several longstanding questions regarding antibody repertoire sel

268 the eukaryotic ribosome and to address many longstanding questions regarding its many roles in the r

269 These results help resolve the longstanding questions regarding the mechanism of action

270 les self-assembled from aqueous surfactants, longstanding questions remain regarding their surface st

271 evelops to direct distinct cell fates remain longstanding questions.

272 In patients with longstanding RA, autoreactivity to ROS-CII changed longi

273 However, despite a longstanding recognition of neutrophil presence at disea

274 onors to a stranger (ADs) with donors with a longstanding relationship with the recipient (traditiona

275 Longstanding reports of polyspecificity of anti-lipid A

276 Despite longstanding research efforts, our understanding of the

277 A longstanding research goal has been to understand the na

278 ication) tasks to assess awareness overcomes longstanding residual methodological problems, and prior

279 enzyme, RuBisCO, attests to the crucial and longstanding role it has played in the biogeochemical cy

280 For those with longstanding sequaelae from incomplete recovery, aesthet

281 enchymal transition (EMT) in metastasis is a longstanding source of debate, largely owing to an inabi

282 The longstanding structure-function paradigm, which states t

283 are superior for cancer genomics has been a longstanding subject of debate.

284 This approach lowers a longstanding technical hurdle to manipulating large prot

285 Shielded covalent (SC) probes eliminate the longstanding trade-off between selectivity and durable t

286 psies from 94 normoalbuminuric patients with longstanding type 1 diabetes using unbiased morphometric

287 Longstanding type 2 diabetes (T2DM) is a risk factor for

288 further tested this SNP for association with longstanding type 2 diabetes without nephropathy (n = 31

289 e significantly associated with dysplasia in longstanding UC.

290 ssors and four nonprogressors suffering from longstanding UC.

291 current evidenced-based data regarding this longstanding unanswered question.

292 A longstanding, unanswered question is whether nuclear org

293 uick, easy, damage-free removal represents a longstanding unmet medical need in neonatal care.

294 munity arises out of alloimmunity has been a longstanding unresolved issue.

295 ward and accurate method that overcomes this longstanding, unsolved problem in radiative transport.

296 tical taxon for this question: despite their longstanding use by humans, they have never been domesti

297 se processes represent an alternative to the longstanding use of stoichiometric organometallic reagen

298 Models in widespread and longstanding use that describe these mixtures apply an a

299 Additionally, our findings challenge the longstanding view that within squamates the Iguania are

300 infinite-length "random" sequences have been longstanding yet incompletely resolved problems.