ライフサイエンスコーパス: loosen

1 re and its association with the central pair loosens.

2 interactions of the adjacent C terminus are loosened.

3 could do so when quaternary restraints were loosened.

4 r, such as osteoporosis and prosthetic joint loosening.

5 increase wall plasticity by a process called loosening.

6 ins known as expansins are mediators of wall loosening.

7 done using cyanoacrylate to prevent abutment loosening.

8 d in enhancing growth by mediating cell wall loosening.

9 nt of osteolysis-associated prosthetic joint loosening.

10 ear debris-associated osteolysis and aseptic loosening.

11 on can contribute to both wall-assembly and -loosening.

12 the cell wall are reduced by continued wall loosening.

13 us contribute to both wall-assembly and wall-loosening.

14 rther modification of histones and chromatin loosening.

15 ding unique insight into the mechanism of CW loosening.

16 is disorders, including mechanical or septic loosening.

17 intercellular gaps below TJs and cell matrix loosening.

18 e apoplast acidification and mechanical wall loosening.

19 ion of periprosthetic osteolysis and aseptic loosening.

20 polyethylene wear (including osteolysis and loosening); 0.652-0.783 sensitivity and 0.976-0.988 spec

21 The wall-loosening actions of beta-expansins are known primarily

22 ial for its plant cell wall binding and wall loosening activities.

23 amine reduced cell wall binding but not wall loosening activities.

24 se binding and concomitantly eliminated wall loosening activity measured either by cell wall extensio

25 t this cavity is essential for the cell wall-loosening activity of LTP.

26 The proteins had substantial wall loosening activity, but no detectable proteolytic activi

27 family and have been shown to have cell wall-loosening activity.

28 ine or asparagine completely eliminated wall loosening activity.

29 Chromatin loosens after the invasion of the red blood cell and the

30 f innermost microfibrils, implying that wall loosening agents act selectively on the cross-linking po

31 expansins function endogenously as cell-wall-loosening agents and indicate that expansins have versat

32 Loosening agents that act on xylans and pectins elicited

33 that XTHs do not represent primary cell wall-loosening agents.

34 Our results show that wall loosening alters microfibril connectivity, enabling micr

35 administered in a two-stage process to first loosen and then graft bone particulate under the Schneid

36 f cell membrane makes bilayer structure more loosen and vulnerable.

37 unravelled the efficacy of cell-cell contact loosening and 3D emigration into an environment mimickin

38 ymerase 1 protein (PARP1) mediates chromatin loosening and activates the transcription of inducible g

39 ryos indicates a potential role in cell wall loosening and anisotropic growth together with pectin de

40 We propose that chromatin loosening and associated initiation of gene expression i

41 lating important genes involved in cell wall loosening and expansion process.

42 litis, and bone damage, resulting in implant loosening and failure.

43 sue results from a balance between cell wall loosening and intracellular pressure.

44 ively distinguish between aseptic prosthesis loosening and low-grade joint infection, and which bioma

45 n differentiating between aseptic prosthesis loosening and low-grade joint infection.

46 wall structure leading to modulation of wall loosening and plant growth.

47 is not a likely mechanism of plant cell wall loosening and that the pollen allergen class of beta-exp

48 The difference between loosening and tightening torque value was also measured.

49 ides a new way to study the dynamics of wall loosening and to measure the wall yield threshold and th

50 ll expansion is controlled primarily by wall loosening and yielding.

51 habetaE interface forming the "empty" E site loosens and singly charged Pi readily escapes to the P l

52 ly in Arabidopsis, are involved in cell wall loosening, and have been implicated in various aspects o

53 surgery, including pseudoarthrosis, hardware loosening, and recurrent or residual disk herniation.

54 orthopedics and is known to provoke aseptic loosening around arthroplasties and is associated with i

55 on of a total elbow arthroplasty for aseptic loosening between 1996 and 2008 were identified.

56 ave also shown that chloroform significantly loosens both cholesterol-poor and cholesterol-rich membr

57 There was no prosthesis loosening, breakage, or infection leading to removal aft

58 unlikely to play a role in acid-induced wall loosening but may function in cold acclimation or cold-t

59 s show that xyloglucan is important for wall loosening by alpha-expansin, and the smaller size of the

60 of action and effects on wall rheology, wall loosening by Cel12A differs qualitatively from the actio

61 tional change, which spatially separates, or loosens, Cav1 molecules within the oligomeric caveolar c

62 llen allergen class of beta-expansins do not loosen cell walls via a proteolytic mechanism.

63 displayed an irregular, elongated shape with loosened cell-cell adhesions and a reduction in E-cadher

64 cytoskeletal organizer RhoA, consequentially loosening cell substrate grip and enhancing movement.

65 EXPB1 selectively loosens cell walls (CWs) of grasses, but its specific bi

66 osynthesis, cuticular changes, and cell-wall loosening-changes that are accompanied by a decline of a

67 tions and are targeted to gene promoters to 'loosen' chromatin for access of transcription factors.

68 (siRNA)-mediated loss of VAPB or PTPIP51 to loosen contacts stimulates, autophagosome formation.

69 he turn connecting H1 and H2 being formed, a loosened core, and H4 partially unfolded and detached fr

70 te cell proliferation, growth, and cell wall loosening, corresponded to the phenotypic severity of th

71 plant is believed to be a major component of loosening due to debris-induced changes in bone cell fun

72 CWs are loosened during growth by expansin proteins, which weake

73 acterised by their ability to stimulate wall loosening during cell expansion.

74 iochemical and biophysical mechanism of wall loosening during cell growth are discussed.

75 role of these genes in regulating cell wall loosening during fruit growth, not in ripening-associate

76 could be explained by the putative cell-wall loosening effect of the in tandem starch binding domains

77 transglycosylase (XET), a putative cell-wall-loosening enzyme active during germination, expansion, a

78 ease of BLCs by acting through the cell wall-loosening enzyme CEL5.

79 Cell wall-loosening enzymes such as CELLULASE5 (CEL5) and a pectin

80 acidification, thereby activating cell wall-loosening enzymes that enable cell expansion in shoots.

81 ivated two EXPANSIN genes encoding cell wall-loosening enzymes; HBI1's DNA binding and transcriptiona

82 is thought to be catalyzed by elusive "wall-loosening" enzymes.

83 o the behavior of leukocytes, which actively loosen epithelial junctions to migrate, and raise the po

84 e EXPA (alpha-expansin) family were found to loosen eudicot cell walls but to be less effective on gr

85 ent expression of the gene encoding the wall-loosening factor XTH33 as a test case for development- a

86 a membrane H+-ATPase and resultant acid wall loosening; FC produced both hyperpolarization and proton

87 a-to-stroma interface; vimentin was found in loosened graft stroma.

88 with previous results, we propose that EXPB1 loosens grass CWs by disrupting noncovalent junctions be

89 A lower incidence of loosening has been found for cobalt chrome-cemented comp

90 sential components of acid-induced cell wall loosening in plants.

91 p proteins in the nucleus concomitant with a loosening in the association between plasmid molecules.

92 outer cells, which directly inhibited their loosening in the elongation zone.

93 e propose that HMS is required for cell wall loosening in the embryo to facilitate cell expansion dur

94 l change in the target and mechanism of wall loosening in the grass lineage possible, involving a new

95 ntribute directly to the enhancement of wall loosening in this region.

96 is a major source of dislocation and aseptic loosening in total hip arthroplasty (THA).

97 Aseptic loosening is a major complication of prosthetic joint su

98 Wall-loosening is a prerequisite for cell wall expansion, a p

99 Second, this wall loosening is triggered by the selective de-methylesterif

100 canning requires that the enzyme transiently loosen its grip on DNA to allow stochastic movement alon

101 s structural ordering throughout gp120 while loosening its association with gp41.

102 low-affinity Mg2+ sites are filled, T4 pol "loosens its grip" on the primer terminus, as shown by a

103 he bacteria to cross the endothelium through loosened junctions.

104 ollen also secretes an unusual expansin that loosens maternal cell walls to aid penetration of the st

105 Such local loosening may facilitate transcription and may transient

106 connectivity in CML, reflecting potentially loosened molecular regulation.

107 nature of a "pretransition" conformationally loosened native state.

108 ape from I(trap) and that escape is aided by loosening nearby native structural constraints, presumab

109 ibosomal proteins, cell cycle, and cell wall loosening, necessary for cytoplasmic growth and cell pro

110 N-terminal lobe, its binding leading to the loosening of a flap, which in unliganded NMT structures,

111 ular cell adhesion molecule 1, disruption or loosening of adherens junctions, and targeted recycling

112 ular cell adhesion molecule-1, disruption or loosening of adherens junctions, and targeted recycling

113 fine-tuned balance between the formation and loosening of adhesive contacts, a process involving inte

114 Loosening of associations has long been considered a cor

115 th arguments that IPL abnormality relates to loosening of associations in SZ.

116 ysfunction in these regions may explain the "loosening of associations" that Bleuler considered to be

117 ion-engendered stimulation of PDK2 activity; loosening of binding as a result of adenine nucleotides

118 The first change is a loosening of cell contact at the apical side of cells on

119 Although the loosening of cells from the biofilm structure was observ

120 at elicited elongation of cells and apparent loosening of cellular junctions upon incubation with Ver

121 Whether loosening of cohesion at the onset of mitosis facilitate

122 ase and Ca(2+) chelation lead primarily to a loosening of contacts within the protein shell, resultin

123 in confers position-dependent tightening and loosening of guide-strand-target interactions.

124 olent course and was thought to have aseptic loosening of his prosthesis until the time of surgery.

125 Affected skin demonstrated loosening of intercellular connections, disruption of de

126 ion of Tiam1 to the membrane ruffles and the loosening of intercellular junctions.

127 mmetry breaking is preceded by an asymmetric loosening of longitudinal, as compared to transverse, an

128 ng to increased histone H4 acetylation and a loosening of nucleosomal-DNA interactions allowing "open

129 Aseptic loosening of orthopaedic implants is induced by wear par

130 erial colonization may contribute to aseptic loosening of orthopaedic implants.

131 edia, periodontitis, endodontic lesions, and loosening of orthopedic implants caused by lipopolysacch

132 such as osteoporosis, fracture healing, and loosening of orthopedic implants.

133 n Drosophila larval salivary glands, a local loosening of polytene chromatin structure associated wit

134 ure or binding to model membranes promoted a loosening of PPXD and C-domain association, while ADP bi

135 bone resorption that accompanies the aseptic loosening of prosthetic joints.

136 native like conformation, besides a moderate loosening of protein folding.

137 experiments have highlighted tightening and loosening of protein structures upon ligand binding, wit

138 Although cell wall loosening of some form appears to be involved, taken tog

139 Loosening of sutures occurred in 20%, and Descemet detac

140 to LA to HA is associated with a progressive loosening of T state constraints within the hinge and sw

141 served in the rad6Delta strain, suggesting a loosening of target specificity in this mutant that lack

142 ments show that unfolding commences with the loosening of tertiary interactions in a native-like inte

143 and the active site 16 A away, leading to a loosening of the active site.

144 ich indeed occurs with a hitherto unreported loosening of the amide backbones of the haemoglobin mono

145 We conclude that the loosening of the array of myosin heads that occurs on ac

146 at detachment was associated with an overall loosening of the biofilm structure and a release of indi

147 n at the 5'-hydroxymethyl group which causes loosening of the C5'-H5' bonds during the reaction coord

148 weakened xylem could result from rupture or loosening of the cellulosic mesh of interconduit pit mem

149 We suggest that PG is involved in cell wall loosening of the endosperm necessary for radicle protrus

150 mplicated in the control of plant growth via loosening of the extracellular matrix.

151 analogues, consistent with an enlargement or loosening of the headgroup binding domain and a decrease

152 Loosening of the heads from the filament surface enables

153 ribonucleoprotein core with disordering and loosening of the individual protein components.

154 parison with the active structure shows that loosening of the latch contributes but is not central to

155 Loosening of the plug by lateral gate opening, a potenti

156 he degradation of the middle lamella and the loosening of the primary cell wall surrounding cells in

157 2.5%), crural fractures (4 patients, 2.5%), loosening of the prosthesis (3 patients, 1.9%), joint di

158 t Abeta in vivo is a metalloprotein, and the loosening of the structure following chelation treatment

159 t to the active site, facilitated by thermal loosening of the substrate, may lead to the first transi

160 rotein may be direct evidence for a relative loosening of the tertiary fold maintaining the "deleteri

161 extracellular calcium is well known to cause loosening of the tight junction with loss of transepithe

162 on, a conformational change that involves a "loosening" of the beta-barrels and a loss or shift of di

163 broadening of amide features, indicating a "loosening" of the beta-structure.

164 By allowing the "loosening" of TJs and an increase in paracellular permea

165 en considered in terms of the tightening, or loosening, of receptor structures that respectively occu

166 ntry and that the pollen secrete proteins to loosen or become new wall constituents of the tube and t

167 Thus, the "loosening" or "remodeling" caused by this point mutation

168 ) testing it on a second patient data set by loosening our filtering criteria, (C) cross-validating w

169 Expansins are small proteins that loosen plant cell walls and cellulosic materials without

170 EXLX1, a bacterial expansin with ability to loosen plant cell walls and whose domain D2 has type-A C

171 ectin methyl esterase (PME) to strengthen or loosen plant cell walls that contain pectin, including s

172 Similarly, ablation of retinoid X receptors loosens PML/RARA DNA binding, inducing terminal differen

173 er ligands, with two different approaches of loosened point chirality, lead to a significant breakdow

174 y to be more common in patients with aseptic loosening, prior studies have focused on LPS, a TLR4-spe

175 postoperative fractures, implant failures or loosening problems occurred; mean Musculoskeletal Tumor

176 is indicative of the action of the cell wall-loosening protein expansin.

177 L1-box cis-element, including two cell wall loosening protein genes GhRDL1 and GhEXPA1.

178 Here, we report a type of cell wall-loosening protein that does not share any homology with

179 oup of the beta-expansin family of cell wall loosening proteins in plants.

180 Expansins are plant cell wall-loosening proteins involved in adaptive responses to env

181 Expansins are cell-wall-loosening proteins that induce stress relaxation and ext

182 Expansins are wall-loosening proteins that promote the extension of primary

183 ycosylase/hydrolase genes encoding cell wall-loosening proteins was enhanced in SHYG overexpressors b

184 Hydrogen bonds to the peptide backbone are loosened rapidly compared with the 5-ns temperature jump

185 Aseptic implant loosening related to implant wear particle-induced infla

186 ng the wall, the increased pH abrogates wall loosening required for cell expansion and growth.

187 ally restores channel function presumably by loosening restraints for tilting.

188 Our results could inform NSP policy to loosen restricted-exchange practice, allowing PWIDs grea

189 s, and need to be revised, most commonly for loosening secondary to wear or dislocation.

190 ss how allelic diversity of CMT1 may reflect loosened selective constraints in a self-fertilizing spe

191 s from patients with septic joint prosthesis loosening (septic total arthroplasty [SeTA]; 9 specimens

192 Tightening and loosening show that ligand binding respectively stabilis

193 are used cautiously so as not to excessively loosen stools and exacerbate anal incontinence.

194 They appear to have wall-loosening, structural, and enzymatic functions.

195 while a reduction in proliferation potential loosens such inhibition and facilitates frequent CSC div

196 with higher ligand reactivity that exhibit "loosened" T state constraints within the globin includin

197 the dilysine pair form the driving force to loosen the cleft, exposing iron; the nearby anion (or ch

198 pe and mutant expansins, we conclude that to loosen the CW, expansin binds highly specific cellulose

199 Furthermore, when we loosen the elastic connection between the heads, the mod

200 einase activity and suggested that expansins loosen the plant cell wall via proteolysis.

201 a good deal of further work has been done to loosen the restrictions and allay concerns about the ris

202 TPases) to facilitate cell expansion by both loosening the cell wall through acidification and promot

203 the pollen tube into the maternal tissues by loosening the cell walls of the grass stigma and style.

204 Sly1 facilitates SNARE complex formation by loosening the closed conformation of Sed5.

205 99, McMichael's "Prisoners of the Proximate: Loosening the Constraints on Epidemiology in an Age of C

206 " conformation of the repressor, effectively loosening the dimer interface and allowing the repressor

207 3 to destabilize the "on" signaling state by loosening the four-helix bundle.

208 l isomers that can be interconverted only by loosening the knot.

209 a pro-oxidant that is potentially capable of loosening the plant cell wall and/or triggering an oxida

210 removal of the Mg2+ from the ternary complex loosens the aromatic side chain packing but leaves the s

211 The mutation M16I loosens the hydrophobic core in the G domain and affects

212 oplasmic-transmembrane domains significantly loosens the inner membrane clasp.

213 y by M. avium subsp. paratuberculosis, which loosens the integrity of the tight junctions.

214 ter reduces the stability of the complex and loosens the interface both in the presence and in the ab

215 This loosens the mannose-binding pocket on the opposite end o

216 of HbA perturb the deoxy T state of HbA by "loosening" the contacts associated with the switch regio

217 Several mechanisms have been proposed for 'loosening' the junctions between endothelial cells to en

218 ulin, and ZO-1 several-fold in glomeruli and loosened their attachment to the actin cytoskeleton.

219 rdware malplacement, three cases of hardware loosening, three perihardware fractures, and two chronic

220 ther with expansins) of controlled cell wall loosening through the transient cleavage and religation

221 Concurrent with the detachment, we find loosened tight junctions between endothelial cells and d

222 ition as well as mechanisms involved in wall loosening to overcome the deleterious effects of soluble

223 globule states, the hydration water networks loosen up, and the protein locally becomes more flexible

224 nlargement of the intracellular gate without loosening up the structural integrity.

225 These data suggest that loosening-up the chromatin structure by histone acetylat

226 ombination for the discrimination of aseptic loosening vs low-grade joint infection.

227 n for preoperative discrimination of aseptic loosening vs low-grade joint infection.

228 from those during creep of the enzymatically loosened wall.

229 plies that allergen homologs may function to loosen walls in growing vegetative tissues as well.

230 r components, and an increasing incidence of loosening was shown for cemented acetabular components w

231 help elucidate expansin's mechanism of wall loosening, we determined the structure of EXPB1 by x-ray

232 ge, it is possible that LS induces cell wall loosening, which can trigger cell wall damage response.