ライフサイエンスコーパス: lose

1 essels when pericyte function is impaired or lost.

2 tion of pore opening and content release was lost.

3 ure in the central brain where retinotopy is lost.

4 f sEH, the protective effect against CNV was lost.

5 nterquartile range, 18.9-32.4 years) with 1% lost.

6 bit inflammation when bacterial viability is lost.

7 odel where immunity can be both acquired and lost.

8 s in mutants in which normal transduction is lost.

9 idae: Meliponini) disassemble when forest is lost.

10 ibition of firing by monoamines or ML297 was lost.

11 red before DNA circularization, cohesion was lost.

12 f Aristotle's writings about plant forms are lost.

13 advancing an average of 0.6 days per species lost.

14 nd thus migrate, though pseudopods are still lost.

15 contrast, on average, slow progressors would lose 0.8, 2.1, and 4.1 dB MD under the same target IOPs

16 IUCN cat III), yet even highest status areas lost 0.13% yr(-1) (IUCN Cat I).

17 ted that, on average, fast progressors would lose 2.1, 6.7, and 11.2 decibels (dB) MD under target IO

18 pulation of sub-Saharan Africa will probably lose 2.3 million disability-adjusted life-years and US$3

19 etween the cohorts in the percentage gaining/losing 2 and 3 lines of vision.

20 onfers sensitivity to "blue" wavelengths was lost 300 million years ago, before the origin of modern

21 Twenty-three eyes (27.7%) gained and 5 eyes lost (6.0%) 10 logMAR or more.

22 the largest reductions in energy intake had lost 7.3% and 3.9% more weight, respectively, compared w

23 at extensively recycle organic material, but lose a fraction as particulate organic carbon (POC) that

24 rate diet, whereas normoglycemic individuals lost a mean of 0.43 kg (95% CI: 0.03, 0.83 kg; P = 0.03)

25 In NUGENOB, diabetic individuals lost a mean of 2.04 kg (95% CI: -0.20, 4.28 kg; P = 0.07

26 trol diet, whereas normoglycemic individuals lost a mean of 2.20 kg (95% CI: 1.21, 3.18 kg; P < 0.001

27 In SHOPUS, prediabetic individuals lost a mean of 6.04 kg (95% CI: 4.05, 8.02 kg; P < 0.001

28 tionality formed diagnostic adducts that had lost a methanol molecule upon reactions with TMMS.

29 Risks were more pronounced for those who lost a noninfant sibling (i.e., >1 year of age) (hazard

30 e outcomes in 622 (73%) participants who had lost a parent as a result of cancer 6 to 9 years earlier

31 nfidence interval: 1.18, 1.95) and those who lost a sibling in adolescence (i.e., between the ages of

32 remely stable and, unlike antibodies, do not lose activity after exposure to high temperatures.

33 FMRP-null PNs lose activity-dependent synaptic modulation, with impair

34 dentify enhancers with recurrently gained or lost activity across CRC specimens.

35 This association was lost after further adjustment for urinary albumin excret

36 tatic lesions, suggesting that ARID1A can be lost after initiation.

37 propagates across networks only if the nodes lose all their supply nodes.

38 Postnatal pulp cells, however, lose all tooth-inducing and tooth-forming capacity follo

39 d in size (c. 33-41 kbp) and content, having lost all photosynthesis-related genes, and are reduced t

40 of bivalent chromatin modifications that are lost along with pluripotency, suggesting a mechanism by

41 rm interactome by predicting that an isoform loses an interaction if it loses the domain mediating th

42 ial cells, Axin1-beta-catenin interaction is lost and beta-catenin escapes ubiquitylation-dependent p

43 in the genus, but behavioural plasticity was lost and regained at least twice.

44 al to replace neurons that have already been lost and thereby to restore visual function.

45 emoval, the split GFP-COase fluorescence was lost, and cellular cholesterol levels returned to normal

46 low pH (excess DeltapH) this interaction is lost, and leads to higher flexibility of the protein and

47 40% of ultrapure silicon is lost as kerf during slicing to produce wafers.

48 Spinach leaves were particularly prone to losing ascorbate during washing, especially with simulta

49 Species and interactions are being lost at alarming rates and it is imperative to understan

50 Species are being lost at an unprecedented rate due to human-driven enviro

51 Of 504 patients in the initial program, 222 lost at least 4 kg of body weight and were randomly assi

52 t anthropogenic activity has been eroded and lost at the Hamble site.

53 Right brain injury causes visual neglect - lost awareness of left space.

54 alteration, and differential propensities to lose BCGM by the higher- and lower-expression copies in

55 y for both receptors to coordinately gain or lose binding in the presence of progesterone.

56 gth nad5 transcript, and degradation of nad5 losing both translation start and stop codons is enriche

57 etic, with a Y102-to-glutamate (E) mutation, lost both activities.

58 , is commonly deleted in prostate cancer and lost broadly in a range of cancers but has unknown signi

59 GLUT3 and Lbx1 (VT3(Lbx1) neurons): the mice lost brush-evoked nocifensive responses and conditional

60 he amount of DNA gained by transposition and lost by deletion during mammal and avian evolution, resu

61 uality-adjusted life-years (QALYs) gained or lost by investing resources in a new strategy compared w

62 The inhibitory effect of the spacing was lost by suppressing the activity of Ras or mitogen-activ

63 loss was common, but actual number of teeth lost, cavity occurrence, average and maximum lingual and

64 e necessarily aged cells that have gradually lost CD19 expression is not known.

65 These mutants also lost chitin-oxidizing activity, which is typically obser

66 found that brown bear populations in Europe lost connectivity since Neolithic times, when farming co

67 She lost consciousness in shock and sustained life-threateni

68 By contrast, hair cells lose contact with the basement membrane, but contribute

69 soils from uncoated fertilizer granules are lost continuously due to volatilization, leaching, denit

70 productivity, but also higher sensitivity to lose coral photosynthesis under heat-stress.

71 ntly associated with improved lipid profile, losing deep subcutaneous adipose tissue with improved in

72 uting disability-adjusted life years (DALYs) lost due to exposure to secondhand vapor.

73 mated disability-adjusted life-years (DALYs) lost due to hip fractures using real-life follow-up coho

74 5964 DALYs (27 per 1000 individuals) were lost due to hip fractures, 1230 (20.6%) of which were in

75 for regeneration of the periodontium that is lost due to periodontitis.

76 x was very stable as the chromophore was not lost during chromatography and displayed a strong red fl

77 ty of adult stem cell pools is progressively lost during homeostatic turnover in several tissues, sug

78 chickens, PGCs are initially formed but are lost during meiosis in the developing ovary, leading to

79 0a functions as a "cell cycle brake" that is lost during melanoma progression to metastasis and provi

80 y the four-cell stage and then reiteratively lost during subsequent mitoses, correlating with transie

81 cations, polyphenols, anthocyanins) were not lost during the dealcoholization, while the losses of vo

82 ith the PSI supercomplex is absent or may be lost during the purification procedure.

83 te exceptional mechanism that was apparently lost during the transition from hemimetaboly to holometa

84 Lost earnings were estimated using Bureau of Labor Stati

85 sion, Satb1-deficient tumor-reactive T cells lost effector activity more rapidly than wild-type lymph

86 , and rhesus macaques, expression of babA is lost, either by phase variation or by gene conversion, i

87 Protein-losing enteropathy (PLE), characterized by loss of prote

88 tivation is an inherent danger in cells that lose epigenetic silencing during developmental reprogram

89 ynapses and stretch reflexes are permanently lost, even after regeneration and reinnervation of muscl

90 4, we noted an increase in excess life-years lost for neoplasms (men: 0.7; women: 0.4), heart disease

91 However the PAs lost forest at a mean rate of 0.18% yr(-1) from 2000-201

92 guably have the most to gain and the most to lose from discontinuing immunosuppression (IS).

93 ars lived with disability, and years of life lost from 15 skin conditions in 188 countries.

94 equired for 4-1BB-mediated costimulation, is lost from chronically stimulated virus-specific CD8 T ce

95 estore the full 100 nucleotides of (T2AG3)n lost from replicated chromosome ends as a single elongat

96 integrin and other costameric proteins were lost from the CMs, and membrane integrity was compromise

97 emperature-rescued F508del-CFTR more rapidly lost function in cell-free membrane patches and showed a

98 /-2 degrees C and 65+/-2% relative humidity) lost glycerol and water over time, as determined by gas

99 knockdown germ cells also fail to replenish lost GSCs.

100 ) division after tissue damage to regenerate lost heart muscle.

101 ygen-binding form of hemoglobin that readily loses heme.

102 -58(E7) autoxidize approximately 8 times and lose hemin approximately 200 times more rapidly than nat

103 One patient lost his graft after several complications, including AM

104 in the maintenance of brain homeostasis but lose homeostatic function during neurodegenerative disor

105 Methylation imprints are mostly lost, however.

106 Mice maintained on a vitamin A-free diet lose HSCs and show a disrupted re-entry into dormancy af

107 te a highly virulent PEDV, but the virus may lose important epitopes for inducing robust protective i

108 change of sample composition with a risk of losing important information or even damaging microplast

109 ed with cilia defects, and cilia motility is lost in a number of ciliated tissues along with a reduct

110 arginine 175 (R175) and this modification is lost in a PRMT5 and WDR77-dependent manner.

111 s, we show that miR-424(322)/503 is commonly lost in a subset of aggressive breast cancers and descri

112 d tocolytics, and this prevention is largely lost in alpha-gustducin-knockout mice.

113 Allostery persisted, but trans-allostery was lost in an oligomerization-deficient GLUT1 variant in wh

114 s for three trophozoite-expressed genes were lost in AN3661-treated trophozoites, which was not obser

115 teria, mosses, and microalgae, but have been lost in angiosperms.

116 This loci was commonly lost in BCa cell lines and we show the deletions extende

117 initiation, Nkx3.1 expression is frequently lost in both humans and mouse models.

118 t of PML nuclear bodies (PML NBs) frequently lost in cancer.

119 ction and biofilm formation ability that was lost in DeltaciaR, indicating that argB was essential fo

120 urbed forests to recover and recapture the C lost in disturbances during 1993-2012.

121 Pth4, an ancient parathyroid hormone lost in eutherian mammals, reveals a new brain-to-bone s

122 The Y chromosome is frequently lost in hematopoietic cells, which represents the most c

123 The beneficial effects of BAR501 were lost in Il-10(-/-) mice.

124 how that the orexigenic effect of ghrelin is lost in mice lacking MRAP2.

125 Importantly, OTUD1 is lost in multiple types of human cancers and loss of OTUD

126 ) is a GC-specific miRNA whose expression is lost in numerous mature B-cell neoplasms.

127 s are anchored by CTCF, and its occupancy is lost in parallel with loop decommissioning during differ

128 in AIH/AISC, though suppressive function is lost in patients upon proinflammatory challenge; protrac

129 PTEN activity is often lost in prostate cancer.

130 rrelates with activation of HSP1; looping is lost in tail-deleted TFAM.

131 Switching was subsequently lost in the Metschnikowiaceae, including Candida albican

132 s detected in the wild type, although it was lost in the mutant.

133 ion of multiple late viral protein mRNAs was lost in the presence of either drug, consistent with the

134 of TLE, parvalbumin neurons are selectively lost in the subiculum, the major output area of the hipp

135 e growing polyketide chain and the enzyme is lost in these cases, which would limit efficient chain e

136 ort: From cancer patient to cancer survivor: lost in transition, in 2005, there has been a national c

137 port From Cancer Patient to Cancer Survivor: Lost in Transition.

138 t costs) and/or ongoing daily expenses while losing income (indirect costs).

139 uORF, in which the repression capability was lost, indicated that the uORF causes ribosome stalling.

140 the cone collapsed and the MS ion signal was lost, indicating that the LS was carried to the MS inlet

141 , such assays often have high background and lose information about PPI dynamics.

142 e have to prevent their collapse and restore lost interactions.

143 al models, the FLCN H255Y mutant protein has lost it tumour suppressive function leading to the clini

144 orced to be continuously unfolded completely loses its ability to contract by folding, becoming a lab

145 7 proliferate normally, but DREAM completely loses its ability to repress genes in G0/G1 while all re

146 In combination with such mutants, hws loses its delayed floral organ abscission ("skirt") phen

147 The results indicate that leptin loses its neurotrophic potential at or near postnatal da

148 Minimally processed pomegranate rapidly loses its overall quality because of high water loss and

149 uncoated, "bare" CNP with high luminescence loses its PL when positively charged macromolecules are

150 Vif defective for the Pr55(Gag) interaction lost its ability to inhibit HIV-1.

151 tiangiogenic and antimetastatic activity but lost its direct antitumor effects due to kinome reprogra

152 Next, we observed the endothelium structure lost its integrity in the co-culture.

153 First, the lost-key situation can be avoided with the use of finger

154 and 16.5% (n = 390) either died (n = 35) or lost KPNC membership status (n = 355) without having a s

155 he prevalent protein denaturant, is the long-lost ligand sensed by the ykkC class of riboswitches, an

156 Conversely, amputees who wish to replace a lost limb must assimilate a neuroprosthetic with the exi

157 y regenerative and can spontaneously replace lost limbs even as adults.

158 Lost lung density was never recovered, highlighting the

159 ach, important biological information may be lost, making the evaluation of viruses obtained during a

160 Cancers that have lost MMR function are common and comprise an important c

161 We also extend the LOST model to accommodate changes in the modulatory stru

162 That is, if one just lost money or won money, this may impact future decision

163 uced body mass; although men in the CR group lost more FFM than the women did, the percentage of FFM

164 e studies found that solid polymeric samples lost more silver during wash compared to fibrous materia

165 African Americans lost more spine BMD than did Caucasians (-0.04 +/- 0.04

166 stically different from baseline; and no eye lost more than 2 Snellen lines from baseline at the time

167 Participants in the behavioural programme lost more weight than those in the brief intervention (a

168 m Xac306 and verified that the mutant strain lost most of its lipase and esterase activities and disp

169 r findings reveal that PUF proteins gain and lose mRNAs with related and emergent biological function

170 The F2 generation loses much of the yield advantage and the plants have he

171 erent evolutionary time scales by reevolving lost mutations and reusing them repeatedly from standing

172 Replacing lost myocardium with new tissue is a major goal of regen

173 o patients with a hypokalemic-alkalotic salt-losing nephropathy.

174 s were not in line with any other known salt-losing nephropathy.

175 ple of such a barrier is that replacement of lost neurons may be insufficient because damage to other

176 Cell replacement of lost neurons using enteric neural stem cells (ENSC) is a

177 y and/or DE-Cadherin are reduced in NBs, NBs lose niche position and relocate to a non-native brain r

178 f 5-6% on cooking while those of Flint maize lost only 2%.

179 reness of transient intermediates represents lost opportunities for discovering materials or understa

180 xchanged between patients and nurses due to: lost opportunities for sharing information; paternalisti

181 sting and treatment procedures can result in lost opportunities to provide timely antiretroviral ther

182 utation carriers among probands represents a lost opportunity to prevent cancer in unsuspecting relat

183 ental genotype, with only 1-4% of CGs either losing or gaining methylation relative to the parent.

184 Crucially, three of these domains would be lost or disrupted by a chromosomal translocation event a

185 ocally in the cells in which the receptor is lost, our study shows that the resulting increase in cir

186 tes that divalent cations are preferentially lost over monovalent cations upon A.C protonation, provi

187 growth factors that promotes restoration of lost periodontal tissues.

188 tosomal recessive hypokalemic-alkalotic salt-losing phenotype.

189 and parity as potential contributors to the lost phenotype.

190 olesterolemia induces HDL lipidomic changes, losing phosphatidylcholine-lipid species and gaining cho

191 n plastid organelles in eukaryotes that have lost photosynthesis; it also suggests that the evolution

192 tion, and Cdc42 null PECs proliferated less, lost polarity and failed to form villous protrusions and

193 ative capacity at birth but this capacity is lost postnatally, with subsequent organ growth occurring

194 ditions was associated with increased annual lost productivity of $9,099 (95% CI, $7,224 to $10,973)

195 Incremental use, expenditures, and lost productivity were evaluated with multivariable regr

196 litating mental illness and a major cause of lost productivity worldwide.

197 on CyanoHAB prevalence as well as potential lost recreation days and associated economic value.

198 ts with inflammatory bowel disease (IBD) who lose response to anti-TNF therapy.

199 robustly rhythmic in old flies, while others lost rhythmicity with age, resulting in constitutive ove

200 Each of these effects on CSQ2, and the lost RyR2 response to changes in luminal [Ca(2+)], was d

201 is intermittently exposed, some individuals lose S. aureus rapidly.

202 The lost Saraswati River mentioned in the ancient Indian tra

203 in the inner ear to proliferate and replace lost sensory receptors.

204 decision strategy characterized by a higher lose-shift rate.

205 nally, we find that mature microglia rapidly lose signature gene expression after isolation, and that

206 ation was stronger (r = 0.474, P = .009) but lost significance when considering eyes with drusen sepa

207 nt, thus averaging methylation across RE may lose significant biological information.

208 Large land areas have lost SOC as a result of land use practices, yet there ar

209 mined and nearly all of them are observed to lose specificity across the entire binding site.

210 issue with improved insulin sensitivity, and losing superficial subcutaneous adipose tissue remained

211 erials have been investigated for renewal of lost supporting periodontal structures and tested for fu

212 , bleeding, or pocket with income; number of lost teeth; sex; education; people living in the house;

213 we show that mitochondria in senescent cells lose the ability to metabolize fatty acids efficiently.

214 Mammalian cardiomyocytes lose the ability to proliferate shortly after birth, and

215 g that an isoform loses an interaction if it loses the domain mediating the interaction.

216 Losing the ability to present neoantigens through human

217 articularly, the ease of fabrication without losing the chemical and biological properties of the cou

218 mation enables structural transition without losing the crystalline symmetry of the parental phase an

219 oosting the interfacial contact area without losing the intrinsic graphitic structure.

220 er the next 70 years, with 66-83% of species losing the majority of currently suitable area.

221 istent with the observation that the culture lost the ability to degrade DCM.

222 eterostrophus MAT genes shows that they have lost the ability to regulate sexual reproduction in U. b

223 its full metabolic activity, apelin-36(L28A) lost the ability to suppress blood pressure in spontaneo

224 SPG5 patients lost the ability to walk independently after a median di

225 The S Typhimurium yfgA mutant lost the characteristic Salmonella rod-shaped appearance

226 tomy and retransplantation in 2, one of whom lost the second graft due to rejection.

227 pansion whereas CD4CD127CD25CD45RA Treg cell lost the TSDR demethylated phenotype.

228 Mutants of p53 have lost the tumour-suppressive functions of wild type p53.

229 posed to weak time-dependent magnetic fields lose their ability to orient in the geomagnetic field.

230 nd nearly half of transplant recipients will lose their allografts by 10 years after transplant.

231 Microglia lose their amyloid-beta-clearing capabilities with age a

232 Proteins tend to lose their biological activity due to their fragile stru

233 e of secondary amines, which, when oxidized, lose their CO2 capture capacity.

234 Vole molars cultured without the braces lose their cusp offset, and mouse molars cultured with t

235 During activation, HSCs lose their lipid droplets (LDs) containing triacylglycer

236 ng different proteins, but in all cases they lose their mechanical integrity.

237 he Sso AcP molecules in the inclusion bodies lose their native-like properties and convert into beta-

238 However, quantum sensors lose their sensitivity in the presence of noise.

239 fibers display rich dynamic behavior without losing their architectural integrity.

240 carrying out chemistry on frameworks without losing their porosity or crystallinity, and in turn achi

241 hough many of these retroviral elements have lost their ability to replicate, those whose insertion t

242 Treg cells lost their ability to suppress effector T cells in the p

243 al predators were abundant and several birds lost their eggs to predators following UAV flights.

244 rthquake and tsunami, many coastal residents lost their lives.

245 PDL cells lost their shape in Mkx(-/-) mice, suggesting changes in

246 n subcutaneous inguinal white adipose tissue lost thermogenic gene expression and multilocular morpho

247 lated from cells with CRISPR-edited MRP loci loses this activity, and ectopic MRP RNA expression rest

248 ucose tolerance at 5 weeks of HFD whereas it lost this effect on glucose and insulin tolerance at 16

249 itation of functional capacity that has been lost through brain insult or musculoskeletal injury.

250 Only 153 (5%) children were lost to follow-up (76 in the co-trimoxazole group and 77

251 single patient who did not achieve SVR12 was lost to follow-up after achieving SVR4.

252 ve survived to 36-months postinjury but were lost to follow-up at all time points.

253 99%) of 518 patients (five participants were lost to follow-up in the intervention group and one in t

254 93.5%) achieved SVR12, 6 relapsed, and 1 was lost to follow-up.

255 No patient was lost to follow-up.

256 , three withdrew from the study, and one was lost to follow-up.

257 w-up time exceeded 6 years, with no patients lost to follow-up.

258 treatments whereby 1 participant per arm was lost to follow-up.

259 One patient in each group was lost to follow-up.

260 roup after parasite clearance and three were lost to follow-up.

261 ts aimed at reclaiming historical grasslands lost to high-yield agriculture.

262 e fraction of Mars' atmospheric gas has been lost to space, contributing to the transition in climate

263 f breakdown and the relative proportion of C lost to the atmosphere vs. stored or transported downstr

264 Salt-losing tubulopathies can affect all tubular segments, fr

265 e expendable in hornworts, as they have been lost twice in derived taxa.

266 Sixty-one patients lost UMRD after a median of 2.5 months (range, 1 to 22 m

267 This association is lost upon exposure to heat, leaving Sll1130 to exhibit i

268 and formation of a complex between them was lost upon mutation of the AtMC1 catalytic site, and that

269 tenuated upon RNaseH incubation and entirely lost upon RNaseA digestion of native chromatin.

270 oduce an altered reading frame, such as stop-lost variants and small insertions and deletions (InDels

271 ate models further adjusted for weight loss, losing VAT or intrahepatic fat was independently associa

272 release and subsequent failure to endocytose lost vesicles.

273 In this pathway, the alkylidene ligand is lost, via ring expansion of the metallacyclobutane inter

274 e during development, the amblyopic eye (AE) loses visual sensitivity whereas the fellow eye (FE) is

275 no out-of-pocket expenses (presumably due to lost wages and continuing expenses).

276 +) mice, which develop intestinal cancer and lose weight despite the absence of reduced food intake.

277 el or postpone a physician appointment until losing weight.

278 ar Western diet with reduced levels of BCAAs lost weight and fat mass rapidly until regaining a norma

279 Conclusion Participants who lost weight over 48 months showed significantly lower ca

280 In the subgroup of patients who lost weight, glycemia, homeostasis model of assessment o

281 tegorical variable was created: 1) eutrophic/lost weight; 2) gained weight; or 3) obese.

282 nd 85 years, the corresponding years-of-life-lost were 0.5 years for high alcohol intake, 0.7 years f

283 ntal disorders in terms of excess life-years lost were for respiratory diseases (men: 0.9; women: 1.4

284 proach, more precise estimates of life-years lost were obtained.

285 lobally, the croplands that are likely to be lost were responsible for 3-4% of worldwide crop product

286 This increase was lost when estrogen-related receptor response element sit

287 This peculiar behaviour is lost when external perturbations overcome a critical thr

288 ndent during development, with the phenotype lost when flies are reared at 19 degrees C.

289 ENaC activation by DHHCs was lost when gamma subunit palmitoylation sites were mutate

290 However, this information is usually lost when global mRNA levels from tissues are measured u

291 Of note, this protection was lost when GOT was knocked down.

292 hat the high conductivity of graphene is not lost when transferred to textile fibres.

293 ver, PTEN causes pathological steatosis when lost, whereas its role in regenerating liver remains unk

294 1 cells only fibulin-4 matrix deposition was lost while other fibulin family members or LTBPs remaine

295 Adaptation to oxidative stress is lost with age in both sexes.

296 in young adult muscles, but this effect was lost with age.

297 when X=Cl, only one equivalent of methane is lost with concomitant formation of benzene from an unsta

298 These properties were lost with continued decomposition at later phases of rip

299 The expression of KCNQ1 was lost with increasing mesenchymal phenotype in poorly dif

300 ss mortality, causes of death, years of life lost (YLLs), years lived with disability (YLDs), disabil