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1 atients revealed that Retinoblastoma (RB) is lost in 100% of these SCLC transformed cases, but rarely
3 n Larsen B's stabilizing frontal portion was lost in 1995, the unstable remaining shelf accelerated,
10 n is more stable than that of Src, an effect lost in a Fyn mutant lacking the palmitoylation sites.
15 Unexpectedly, this coupling was chronically lost in a mouse model of mesial temporal lobe epilepsy (
16 ed with cilia defects, and cilia motility is lost in a number of ciliated tissues along with a reduct
18 lular potential is reset, DNA methylation is lost in a series of "sequential waves." The mechanism un
19 s, we show that miR-424(322)/503 is commonly lost in a subset of aggressive breast cancers and descri
20 obial sensor SLAMF1 (also known as CD150) is lost in a subset of patients with an aggressive CLL that
21 n molecule for DNA viruses whose function is lost in a variety of cancers has coincided with the appr
22 cal regulator of autophagy and apoptosis, is lost in a wide variety of tumors, although the mechanism
23 ceae family through gene duplication and was lost in A. thaliana, contributing to leaf simplification
24 by blockade of spinal and supraspinal A3AR, lost in A3AR knock-out mice, and independent of opioid a
25 ortant immune-regulatory roles that would be lost in AATD, yet adaptive immune responses in the lung
33 hibernation as an overwintering strategy was lost in all other primates in mainland Africa, Asia, and
35 he sweet, umami, and bitter tastes have been lost in all penguins, an order of aquatic flightless bir
39 Allostery persisted, but trans-allostery was lost in an oligomerization-deficient GLUT1 variant in wh
40 s for three trophozoite-expressed genes were lost in AN3661-treated trophozoites, which was not obser
43 e response to the same MC4R agonist was only lost in animals lacking G(s)alpha specifically in the PV
44 ), the temperature at which motor control is lost in animals, has the potential to determine if speci
46 yroglobulin, to which tolerance is typically lost in autoimmune thyroiditis leading to hypothyroidism
47 nd this extension of lifespan was completely lost in backgrounds containing a mutated DAF-16 gene.
48 1/beta2) genes but alpha2-tubulin genes were lost in basidiomycetes and beta2-tubulin genes were lost
54 um and lung, and its protective effects were lost in both Ifnar1(-/-) and germ-free mice, revealing e
55 udy, we demonstrate that PTF1A expression is lost in both mouse and human PanINs, and that this downr
56 that the remaining wild-type Bap1 allele was lost in both spontaneous ovarian tumors and mesothelioma
58 is mediated by CTCF, and this regulation is lost in BWS, leading to aberrant overexpression of growt
59 Pase-activating protein and tumor suppressor lost in cancer by genomic deletion or epigenetic silenci
60 The chromatin-remodeler ATRX is frequently lost in cancer cells that use ALT (alternative lengtheni
61 ies of apoptosis-effector genes are commonly lost in cancer development, in comparison to proliferati
65 t sites between transfected cells, which was lost in cells expressing cis- or predicted trans-dimeriz
66 Furthermore, the influences of butyrate are lost in cells lacking HIF, thus linking butyrate metabol
69 This diurnal radioprotective effect becomes lost in circadian mutants, consistent with asynchronous
77 tration, synaptic plasticity was selectively lost in D2, but not D1 inputs to the ventral pallidum.
78 -affinity rex sites and become diminished or lost in DCC-defective mutants, thereby converting the to
83 ction and biofilm formation ability that was lost in DeltaciaR, indicating that argB was essential fo
86 l human genome, we identify megabases of DNA lost in different human lineages and pinpoint large dupl
89 ow here that meiotic crossover patterning is lost in Drosophila melanogaster mutants that lack the Bl
93 s of H3K9me3 at the Xist promoter region are lost in embryonic stem (ES) cells, and ES-cloned embryos
98 s mammalian hair cells are not replaced when lost, in fish they constantly renew and regenerate after
100 knocked down, polarization of active Rac1 is lost in FRET experiments and culminates in shunting migr
101 during early G1 phase of each cell cycle and lost in G2 phase, but it is not known when TAD structure
102 liferative response after cardiac injury was lost in G3 Terc(-/-) newborns but rescued in G3 Terc(-/-
104 coupled to RGCs via gap junctions that were lost in glaucoma, whereas uncoupled ACs were largely una
110 lian Ste20-like serine/threonine kinases, is lost in >95% pancreatic cancer through proteasome-mediat
112 (2) = 0.83), but this optimized phenotype is lost in heart failure, suggesting restoration of normal
114 d cAMP concentrations and activate PDE4B are lost in hepatocytes deleted for both catalytic subunits
116 c acetyl CoA, PC activity, and lipolysis was lost in high-fat-fed rats, a phenomenon reversible by IL
118 tible to HIV in vitro and are preferentially lost in HIV-infected individuals compared with CMV-speci
119 stribution of RvD1 biosynthetic machinery is lost in hMSG with SS; (3) RvD1 levels in mSMG cell cultu
120 populations of (225)Ac(3+) ions: one rapidly lost in human serum and one that remains bound to the US
123 mologue (PTEN) gene is frequently mutated or lost in human tumours and syndromes that predispose indi
125 f eosinophils and protection against EAE was lost in IL-33(-/-) mice and upon neutralization of IL-5.
132 n the third trimester of human pregnancy are lost in large-for-gestational age infants and may be reg
136 ins an apparent duplication with one paralog lost in mammals, and a number of crustacean genomes (lik
138 an obligate requirement for survival that is lost in mature hematopoietic and in transformed epitheli
139 conclude that NF1 is a key tumor suppressor lost in melanomas, and that concurrent RASopathy gene mu
140 cillation in markers of mRNA translation was lost in memory-deficient transgenic mice lacking calmodu
141 tasis suppressor protein whose expression is lost in metastatic bladder and prostate carcinomas.
143 ediated improvement in glucose tolerance was lost in mice coinjected with a GLP-1 receptor antagonist
144 licits an anti-contractile effect, which was lost in mice deficient in eosinophils, mimicking the obe
148 t delivered to PVN to inhibit food intake is lost in mice lacking G(q/11)alpha in the PVN but not in
151 ithrombotic effects of exenatide were partly lost in mice transplanted with bone marrow from Glp1r(-/
152 d Flox mice to 47% after NTS treatment), was lost in mice with hepatic deletion of Pcsk9 (5% in both
155 -directed DNA methylation activities and are lost in mop1 and mop3 mutants, but the nearby genes rare
160 gamma/delta recombination in fetal thymus is lost in mTORC1KO thymus, leading to elevated gammadeltaT
161 3K36 trimethylation (H3K36me3) is frequently lost in multiple cancer types, identifying it as an impo
168 cantly diminished SOCE in NPCs, and SOCE was lost in NPCs from transgenic mice lacking Orai1 or STIM1
171 vasoconstriction observed in Young MAs were lost in Old MAs along with impaired dilatation to calcit
173 match, and how much information is gained or lost in one allele of the polymorphism or mutation relat
178 gration and airway infiltration were all but lost in P1V1 and P1V3 mice during lipopolysaccharide (LP
180 s are anchored by CTCF, and its occupancy is lost in parallel with loop decommissioning during differ
181 early stages of synapse development and were lost in parallel with maturation of the network due to o
182 c nucleus on intracerebellar connectivity is lost in Parkinson's disease, which may contribute to pat
184 in AIH/AISC, though suppressive function is lost in patients upon proinflammatory challenge; protrac
188 bility of scFvSCE5-scuPA to lyse thrombi was lost in plasminogen-deficient mice, but could be restore
190 icals, occurring in gas phase, is completely lost in polar solvents as predicted by theoretical compu
193 BAP1 expression was maintained, rather than lost, in primary melanomas compared with nevi and normal
195 and (3) it can retrieve significant peptides lost in protein-centric quantification for further downs
198 ive effects conferred by Parp1 deletion were lost in Rag2(-/-) x Parp1(-/-) mice, highlighting the ro
211 ility to establish this partnership has been lost in some plant lineages like the Brassicaceae, which
213 nes and gene functions that were acquired or lost in specific lineages during vascular plant evolutio
214 long the metazoan stem lineage and were then lost in sponges and placozoans or evolved at least twice
215 kinases are activated and hippo signaling is lost in sporadic human malignancies remains unknown.
216 that the robust response to IFN-alphabeta is lost in Stat1-Stat2 double-knockout macrophages suggest
219 their integrity, and this functionality was lost in synthetic peptides harboring amino acid substitu
221 strate that IL-9 production is progressively lost in Th9 cultures during several rounds of differenti
223 haploinsufficiency of Egr1 and Apc, 2 genes lost in the 5q deletion, are key players in the progress
225 -Guerin (BCG) vaccine-induced protection was lost in the absence of ESAT-6-dependent cytosolic contac
226 n of CXCL5 secretion by P2X4 antagonists was lost in the absence of extracellular Ca(2+) Reciprocally
230 passaged in the presence of rifampin but was lost in the absence of the drug, suggesting that the dup
232 possessed two pdf homologs, one of which was lost in the arthropod or arthropod/tardigrade lineage, f
233 s (mesDA) are the nerve cells preferentially lost in the brains of Parkinson's disease patients.
234 (HSPCs), whereas they are hyperactivated and lost in the circulation when wild-type HSPCs are absent,
237 +) dynamics at the heminode and terminal was lost in the dysmyelinated axon from Long-Evans shaker ra
238 H3K27me3-dependent imprinting is largely lost in the embryonic cell lineage, but at least five ge
240 he ancestral cytoplasmic IF protein gene was lost in the entire panarthropod (onychophoran + tardigra
241 one (Pth)4 in zebrafish that was secondarily lost in the eutherian mammals' lineage, including humans
245 signal-regulated protein kinase 5 (Erk5) is lost in the hearts of obese/diabetic animal models and t
249 nolic acids) of almond kernels substantially lost in the initial phase; afterward these components gr
251 ancestral amniote hippocampus was gradually lost in the lineage leading to birds, and birds expanded
252 Lindau (VHL) is a tumour suppressor that is lost in the majority of clear cell RCC (ccRCC) cases.
254 t, the capacity for IBC/IPhC regeneration is lost in the mature organ of Corti, and consequently IHC
256 plex in true toads (Bufonidae), where it was lost in the most recent common ancestor, preceding a rad
257 ing the incidence of extra teeth, which were lost in the mouse lineage 45 million years ago (Ma).
259 totopic representation present in the ELL is lost in the nucleus lateralis (NL) of the TS, while a ro
261 ake of carotenoids but that this function is lost in the predominant mutant isoform in white recessiv
263 ion of multiple late viral protein mRNAs was lost in the presence of either drug, consistent with the
264 ), and CATAC-mediated expression rhythms are lost in the presence of null mutations in either cyc or
268 ato and found only in Rosids (but apparently lost in the Rosid A. thaliana) for which we propose the
269 f a single transcription factor binding site lost in the snake lineage reinstated full in vivo functi
271 of TLE, parvalbumin neurons are selectively lost in the subiculum, the major output area of the hipp
272 ing that 3.2 Mbp with population support was lost in the transition from GRCh37 with 13.7 Mbp added t
273 patients, and these variants were routinely lost in the tumor cells by chromosomal deletions (e.g.,
276 that is typical for pericyclic reactions is lost in their mechanistic cousins, cycloaromatization re
279 e growing polyketide chain and the enzyme is lost in these cases, which would limit efficient chain e
280 functional cp-ndh genes have been completely lost in these orchids or whether they have been transfer
285 ort: From cancer patient to cancer survivor: lost in transition, in 2005, there has been a national c
289 el mechanism of Nrf2 regulation that may get lost in tumors and by which IER3 exerts its stress-adapt
291 rs, one or more future drug options had been lost in two participants (Kaplan-Meier estimate 0.7%) in
298 tream, whereas the 5448 Deltasda1(M-) strain lost in vivo selection of CovRS mutations and was sensit
300 ast, a subset of "ERAAP-edited" peptides was lost in WT cells, and ERAAP-deficient cells presented a
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