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1 ti-CD22 ADCs (CD22 0 Jurkat, all inactive at low doses).
2 rferes with acupuncture analgesia, even at a low dose.
3 rism agent that is highly infectious at very low doses.
4 1 triple negative breast cancer in mice at a low dose (1.7 micromol kg(-1), 1 T), but not in oestroge
5 ree of the treatment group subjects received low-dose (1 x 10(10) vector genomes) and 3 high-dose (1
6 with AHF who were previously receiving no or low-dose (12.5 mg or 25 mg daily) spironolactone and had
7 ezepelumab at a dose of 70 mg every 4 weeks (low dose; 145 patients), 210 mg every 4 weeks (medium do
8 afety and effectiveness of a next-generation low-dose (2-microg/mm(2) surface dose of paclitaxel) DCB
10 signed to receive either placebo or a single low dose (50 mg) of the D2/D3 receptor antagonist amisul
15 t compared high doses of ACEI or ARB against low doses among patients with HF with reduced ejection f
16 ere are specific aspects of the use of these low doses and low plasma concentrations that require spe
17 at in BALB/c mice R21 is immunogenic at very low doses and when administered with the adjuvants Abisc
20 Here we show that a combination therapy of low-dose anti-CD3 with a clinical-grade self-containing
21 evaluated cost-effectiveness of ticagrelor + low-dose ASA in patients with prior MI within the prior
22 long-term treatment with ticagrelor 60 mg + low-dose ASA yields a cost-effectiveness ratio suggestin
23 to ASA alone, ticagrelor 60 mg twice daily + low-dose ASA, or ticagrelor 90 mg twice daily + low-dose
25 atelet therapy (3613 of 4527 [80%]) received low-dose aspirin (50 to 150 mg/d); 914 (20%) received hi
26 A growing body of research suggests daily low-dose aspirin (ASA) reduces heart diseases and colore
27 3 years earlier, treatment with ticagrelor + low-dose aspirin (ASA) reduces the risk of cardiovascula
29 ular (CV) death, MI, or stroke compared with low-dose aspirin alone, but at an increased risk of majo
30 used concurrently with an antiplatelet drug (low-dose aspirin and a VKA: 3.6% of cases and 1.1% of co
31 no association between postdiagnosis use of low-dose aspirin and cancer-specific mortality among pat
34 performed a cohort study of 601 527 users of low-dose aspirin for primary or secondary prevention in
38 study is to evaluate the impact of DHA with low-dose aspirin therapy on periodontal bacterial profil
40 e independent cohorts in the United Kingdom, low-dose aspirin usage was not associated with increased
41 rvals (CIs) for cancer-specific mortality by low-dose aspirin use after adjusting for potential confo
43 s meta-analysis including patients on mainly low-dose aspirin, NOACs were found to be more effective
44 under the curve [AUC] 24 968) compared with low-dose (AUC-38 225) or standard-dose NCEM (AUC-38 685)
47 or in healthy HIV-1-infected persons, single low-dose BMS-936559 infusions appeared to enhance HIV-1-
48 ogressed to carcinoma in rats given neonatal low-dose BPA with adult T+E but not in rats given adult
50 ON: In mild recent-onset asthma, once daily, low-dose budesonide decreases SARE risk, reduces lung fu
54 apitulated by the systemic administration of low-dose carboxyatractyloside, a specific inhibitor of A
55 DISCUSSION AND The theoretical merits of the low-dose carcinogenesis hypothesis are well founded with
59 single dose of CAR-19 T cells 2 days after a low-dose chemotherapy conditioning regimen of cyclophosp
62 nt of extinguished preference in response to low-dose cocaine administration did not differ between g
64 Moderate-strength evidence suggests that low-dose colchicine is as effective as high-dose colchic
65 dation 2: ACP recommends that clinicians use low-dose colchicine when using colchicine to treat acute
67 ch as exhaled breath condensate analysis and low dose computed tomography (CT) as an alternative to c
68 ing cessation counseling in conjunction with low-dose computed tomography (LDCT) lung cancer screenin
69 yclic voltammetry in male rats, we show that low-dose, continuous amphetamine treatment, during self-
71 ase 2 trial, we assigned patients to receive low-dose crizanlizumab (2.5 mg per kilogram of body weig
72 ast-enhanced CT (CECT) and PET combined with low-dose CT (PET/CT) at baseline, after 2 cycles of chem
73 inarily analyse the usefulness of Whole-Body Low-Dose CT (WBLDCT) in the evaluation of patients with
80 proach should be used for future lung cancer low-dose CT programmes; that individuals who enter scree
82 y-specific recovery coefficient based on the low-dose CT scan, method 3 was an enlarged volume of int
84 reatment; and planning for implementation of low-dose CT screening should start throughout Europe as
89 could be increased using MVA-5T4, metronomic low-dose cyclophosphamide, or a combination of both trea
92 ts were randomized (3:1) to treatment with a low-dose DCB or an uncoated percutaneous transluminal an
97 , we demonstrate that acetaminophen, even at low-dose, disrupts the integrity of TJ and cell-matrix a
98 treatments of mice with MN-anti-miR-10b and low-dose doxorubicin resulted in complete regression of
100 Taken as a whole, the results suggest that low-dose E2 replacement might be a potentially promising
103 riment designed to investigate the effect of low-dose environmental chemical exposure on normal mamma
108 We delineate the effects upon physiological low-dose exposure to ubiquitous endocrine disrupting che
111 he supporting principle is that use of these low doses for a limited time in well-controlled, small p
114 s: BSJYD high dose group, middle dose group, low dose group, captopril group, and control group.
115 one (an acute allergic skin reaction in the low-dose group) was assessed to be causally related.
116 [18%] in the placebo group, 17 [30%] in the low-dose group, and 20 [34%] in the high-dose group).
117 (33%) to the placebo group, 57 (33%) to the low-dose group, and 58 (34%) to the high-dose group.
118 ient in the placebo group, three (5%) in the low-dose group, and two (3%) in the high-dose group; onl
121 e contrasted MTD strategies as compared with low-dose, high-density metronomic strategies (LDM) for t
124 ry secondary analysis of the PREMILOC (Early Low-Dose Hydrocortisone to Improve Survival without Bron
126 al trial of extremely preterm infants, early low-dose hydrocortisone was not associated with a statis
127 D127(+) CD25(high) cells are unresponsive to low-dose IL-2 and in patients have marked proliferative
128 otriene C4 (LTC4), given in combination with low-dose IL-33 to naive wild-type mice, led to synergist
129 y visualized by using the recently developed low-dose imaging technique of transmission electron micr
131 produced an inverted-U dose-response, where low doses improved performance but higher doses, similar
133 nd to have robust P2X7 receptor occupancy at low doses in rat with ED50 values of 0.06 and 0.07 mg/kg
134 f mRNA results in high protein expression at low doses in vitro (<600 pM) and in vivo (1 mg kg(-1) ).
135 Attempts to induce high-avidity T cells by low-dose in vivo vaccination failed because this strateg
140 icantly protected animals against a repeated low-dose intrarectal challenge with pathogenic SIVmac251
141 ey resulted in enhanced protection against a low-dose intravaginal challenge with a heterologous stra
142 ed with enhanced protection against repeated low-dose, intravaginal challenges with heterologous SIVs
144 High-dose intravenous NAC administered with low-dose intravenous nitroglycerin is associated with re
146 e (CHD) are exposed to increasing amounts of low-dose ionizing radiation (LDIR) from cardiac procedur
147 ortant for studying biological effects under low-dose ionizing radiation, safety control in medical r
150 formation, is transiently elevated following low dose irradiation and regulates transcription of its
152 e with select antiepileptic drugs (AEDs), in low doses, is usually well tolerated and efficacious.
154 ks of 15 to receive placebo (normal saline), low-dose ketamine (0.5 mg/kg), or high dose ketamine (1.
155 Two rapid-acting antidepressant strategies, low-dose ketamine (KT) and sleep deprivation (SD) therap
160 e hemodynamic support after cardiac surgery, low-dose levosimendan in addition to standard care did n
161 impact the modeled force of infection; iii) low-dose linear, concave functions allow the basic repro
162 considered when selecting a functional form: low-dose linearity, scalability, concavity, and whether
164 Credible evidence of imaging-related low-dose (<100 mGy) carcinogenic risk is nonexistent; it
165 wing promise for efficient spectrum imaging, low-dose mapping of beam-sensitive specimens, trace elem
166 015 evaluated the scientific support for the low-dose mixture hypothesis of carcinogenesis and develo
169 t alanine aminotransferase elevations in the low-dose (n = 1) and higher-dose (n = 2) cohorts were tr
171 rify the mechanism and to define the role of low-dose naltrexone for treatment of Hailey-Hailey disea
178 th severe Hailey-Hailey disease treated with low-dose naltrexone who achieved clinical resolution of
180 te the safety, efficacy, and tolerability of low-dose naltrexone, in conjunction with single-day bupr
183 -dose NAC (29 g over 2 days) with background low-dose nitroglycerin (7.2 mg over 2 days) on early car
185 fortified in juice or food, at a relatively low dose of 15 mug/d, was effective in increasing serum
186 t of appropriate antipsychotic medication, a low dose of amphetamine enhances brain processes associa
187 2-depleted (SOD2(+/)(-)) mice in response to low dose of angiotensin II (0.3 mg/kg per day) compared
188 IDs to date, it appears that a comparatively low dose of celecoxib administered to low-risk subjects
193 ertilized one-cell stage eggs, followed by a low dose of irradiation, frequently results in random in
195 2%) mice previously infected with a relative low dose of L. monocytogenes CD44(hi)CD4(+) T cells from
196 as inhibition of actin polymerization with a low dose of latrunculin A disrupts the targeting of micr
197 t neutrophils do not directly respond to the low dose of LPS used in the study (2 ng/kg body weight).
198 te monotherapies) and single gametocytocidal low dose of primaquine, vector control and surveillance.
199 d a high number of functional islets using a low dose of recombinant collagenase enzyme mixture (RCEM
201 ion studies uncovered surprising benefits of low doses of ABBV-075 coupled with bortezomib and azacit
205 roperties would be similarly effective, (ii) low doses of antibiotics can be as effective as high dos
206 the early 1950s, amid initial findings that low doses of antibiotics served as growth promoters in a
207 er humic acid (SRHA) at pH 5.1 +/- 0.2 using low doses of chlorine (0.1 to 0.50 mg free Cl2/L), with
209 Finally, we review evidence suggesting that low doses of DA agonists that effectively treat TS decre
212 suggest non-targeted effects (NTE) occur for low doses of high linear energy transfer (LET) radiation
214 t activated CD8 T cells become responsive to low doses of IL-2 more quickly than CD4 T cells, and pro
216 ine stem cells (GSCs) to survive exposure to low doses of ionizing radiation (IR) as a model of adult
217 chloride channel modified to be activated by low doses of ivermectin (but not glutamate) is highly ef
218 utcomes is unclear; although, treatment with low doses of levothyroxine, which is usually used to tre
219 experimental findings have demonstrated that low doses of low energy helium ions can be used to tailo
221 the pro-tumoural role of MG, we showed that low doses of MG induced AGEs formation and tumour growth
229 y, we showed that combination treatment with low doses of rapamycin and carbamazepine was able to att
230 taining the potential biological activity of low doses of resveratrol has not been extensively studie
231 pproved collagen sponges are used to deliver low doses of small molecule glycogen synthase kinase (GS
232 raction between FKBP12 and calcineurin, with low doses of the Food and Drug Administration (FDA)-appr
233 to cancer cells upon brief irradiation with low doses of visible light, and potent at sub-micromolar
234 trials have been limited by short duration, low doses of vitamin D, variability in participants' vit
236 ng epithelial cells chronically exposed to a low-dose of single-walled carbon nanotubes (SWCNTs).
238 sequentially into one of three dose cohorts (low dose [one participant], intermediate dose [one parti
239 Antibiotic administration to mice before low dose oral inoculation increases L. monocytogenes gro
244 s with acute stroke, the prophylactic use of low-dose oxygen supplementation did not reduce death or
247 cebo group (difference, 0.12 liters with the low dose [P=0.01], 0.11 liters with the medium dose [P=0
250 of 15-PGDH inhibitors to initiate or amplify low-dose PGE2-mediated cervical ripening or (ii) EP2 rec
252 re information is needed about the safety of low-dose primaquine in populations where G6PD deficiency
255 n inactivation alone, or in combination with low-dose r-tPA, did not lead to fibrinogen degradation,
256 nt Ph+ leukemia cells to investigate whether low dose radiation (LDR) in combination with TKI therapy
259 e need for dose optimization in imaging: the low-dose radiation of medical imaging has no documented
260 arly important for chemical exposures in the low-dose range that may be affecting crucial cancer hall
261 nt, our results support the possibility that low-dose rapamycin, while not targeting the underlying m
262 ncer who require or choose active treatment, low-dose rate brachytherapy (LDR) alone, EBRT alone, and
264 assay demonstrated better islet function for low-dose RCEM (area under the curve [AUC] 24 968) compar
267 dle- and high-dose data do not constrain the low-dose response, and different dose-response forms tha
268 ay antithrombotic therapy approach combining low-dose rivaroxaban (in place of aspirin) with a P2Y12
270 ay antithrombotic therapy approach combining low-dose rivaroxaban with a P2Y12 inhibitor for the trea
272 4]) patients on placebo, 22 (39% [27-52]) on low-dose SCIg, and 19 (33% [22-46]) on high-dose SCIg ha
273 ir addition to a DNMTi, thus devising a new, low-dose, sequential regimen that imparts a robust anti-
275 10-<20 mg, simvastatin 40-<80 mg), and 12.9% low-dose statins (atorvastatin <20 mg, rosuvastatin <10
276 tion of a hormetic effect of MG defined by a low-dose stimulation and a high-dose inhibition of tumou
280 cles were injected in right eyes of 14 rats (low dose; study group I, high dose; study group II).
281 tacrolimus variability in a "Symphony" style low-dose tacrolimus based regime, by collecting data fro
283 rall, combination fludarabine-melphalan with low-dose TBI after haplocord stem cell transplant assure
284 essential portion of the field of view and a low-dose technique to image the remainder of the body.
286 immune checkpoint blockade, chemotherapy, or low-dose TNF, complete tumor regression and long-lasting
289 nary evidence indicates that the addition of low-dose total body irradiation (TBI) (2-4 Gy) to reduce
290 offer a preclinical proof of concept for the low-dose use of isoform-specific PI3Kdelta/gamma inhibit
293 as cationic adjuvant formulation 09, render low-dose vaccination a feasible and promising approach f
294 ells of higher functional avidity induced by low-dose vaccinations showed higher cytokine release per
296 e risk reductions were 25% (95% CI 6-41) for low-dose versus placebo (p=0.007), 30% (12-46) for high-
297 d has the potential to be used for accurate, low-dose vessel-specific morphologic and physiologic ass
299 ally, we evaluated the anti-cancer effect of low-dose YC-1 (1 mg/kg) + G (2 g/kg) and I (1 unit/3 g G
300 a HIF-1alpha inhibitor, and we revealed that low-dose YC-1 (10 microM) suppressed HIF-1alpha expressi
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