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1 cal air pollution on daily deaths: effect of low levels.
2  effectively reduces such antagonism to very low levels.
3 med during early or late adult life, even at low levels.
4 e PFASs were ubiquitously detected albeit at low levels.
5 ysis rate would reduce activity to extremely low levels.
6  urinary TCS levels compared with those with low levels.
7  nM) of vitamin D for 24 h demonstrated that low levels (0.5 to 5 nM) significantly increased the TRA
8 etation of the TVA's selectivity is based on low-level acoustic cues: compared to control sounds, voc
9  Previous research showed the propagation of low-level acoustic features of speech from posterior sup
10 tical for homeostasis; however, when chronic low level activation of the immune response with or with
11 sponses observed between PIVs and persistent low-level AdV shedding may account for the higher method
12 imer's disease neuropathology, 56 (26%) with low-level Alzheimer's disease neuropathology, 45 (21%) w
13 cript levels among circulating monocytes and low levels among circulating B cells, and, commensuratel
14 his study demonstrates that pigs can support low-level amplification of CWD prions, although the spec
15 n of half-cell electrodes provided the logic low level and decoupled configuration relaxed the system
16 ited phylogenetic conservation, expressed at low levels and characterized by tissue/organ specific ex
17 bout the impact of exposures-particularly at low levels and during susceptible developmental stages.
18 clear export signal, it is expressed at very low levels and is unable to reverse methionine and adeni
19 lly glaciated Snowball Earth state given the low levels and large fluctuations of atmospheric CO2 The
20 arent locomotion speed, indicating that both low-level and high-level visual properties of the adapti
21 cessed and, subsequently, were joined using "Low-level" and "Mid-Level" data fusion methods.
22 (weaken) during El Nino (La Nina), producing low-level anticyclonic (cyclonic) relative vorticity ano
23  full length SMN protein is produced at very low levels ( approximately 10%).
24 nd the mmpR5 locus, which is associated with low-level BDQ resistance in M. tuberculosis Both genes e
25                           Patients with only low level BK viremia expressed low frequencies of polyfu
26 icated that the concentrations of Hg were at low levels both in mushrooms and forest topsoils for a m
27 ssion decreased extractable activity to very low levels but had little effect on phenotype or ascorba
28 ales during the breeding season, but at very low levels by females.
29           Prenatal alcohol exposure, even at low levels, can influence craniofacial development.
30 an adenovirus type 8 (HAdV-D8), whereas only low level circulation (19%) of HAdV-D8 was observed outs
31  introduced that facilitates the analysis of low-level components in high dynamic range mixtures by s
32  during network activity, whereas continuous low-level concurrent inhibition and excitation may contr
33 esults of recent studies have suggested that low-level constitutive activity of TRPV3 induces EGFR-de
34  been known that B and T lymphocytes exhibit low-level, constitutive signaling in the basal state (to
35  development of grid-scale ascending motion, low-level convergence and the acceleration of tangential
36                      The association between low-level crystalline silica (silica) exposure and morta
37 ans use an optimal strategy when integrating low-level cues proportional to their relative reliabilit
38 a analysis provided experimental evidence of low-level detection of the target "rare" species at biom
39                                  Relative to low-level drinkers (<60 drinks/year), hazard ratios were
40                                Compared with low-level drinkers who never binged, moderate drinkers (
41        Improved understanding of the risk of low level DSA is needed.
42                  Kidney transplantation with low-level DSA with or without a low positive XM is a rea
43 ronmental oxygen levels then crashed to very low levels during the subsequent extremely negative Shun
44  DA even in biological fluids where DA is at low levels, e.g., in the central nervous system, which i
45 with: (1) a sharp reduction of the amount of low-level, energy-related visual information encoded by
46 her risk of leukemia is associated with very low level exposure to environmental benzene.
47                                              Low-level exposure to BPA is ubiquitous in human populat
48                    We showed that prolonged, low level expression of Cas9 and sgRNA often fails to el
49                                              Low-level expression of the human ClC-Kb channel in mamm
50  through increased meridional convergence of low-level, externally sourced moisture.
51 ontributes to OFC encoding of both concrete, low-level features of expected outcomes, and abstract, i
52 r why atmospheric oxygen remained trapped at low levels for more than 1.5 billion years following the
53                                   Persistent low-level hemolysis (LLH) during continuous-flow mechani
54 issues obtained from PrEP Participant B, but low-level HIV RNA or DNA was intermittently detected fro
55 uring suppressive ART and is associated with low-level HIV-1 RNA in blood, better immune status, and
56                                              Low-level HIV-1 RNA in CSF is common during suppressive
57 lopment typically contains flavonols at very low levels, however.
58 gh JCV antibody levels, 13.3% of donors with low levels i(4 of 30), and 0% of seronegative persons (0
59 nsory neurons and was expressed at extremely low level in the muscle tissue.
60 ts membrane input resistance from falling to low levels in a light-independent manner.
61                    Although normally at very low levels in adult DRG neurons, Neto2 protein expressio
62 ng juvenile vocal learning, and decreases to low levels in adults after learning is complete and the
63 All var genes are silenced or transcribed at low levels in blood stages (gametocyte/ring) of the para
64 ew, such as Klf1, were detected only at very low levels in few precursor cells.
65 mined that endogenous betaine was present at low levels in germinal vesicle (GV) stage mouse oocytes
66 xpressed in mouse islets but present only at low levels in human islets, so that it reads (GALR3) and
67 1 We found that Cyp27b1 is also expressed at low levels in non-renal cells, in which transcription wa
68  the tumor suppressor protein p53 is kept at low levels in part due to ubiquitination by MDM2, a proc
69 ig and germ cells in the testes, but at very low levels in Sertoli cells.
70 ormal daily gluten-containing diet increased low-level intestinal inflammation.
71 sterlies, which disrupted the South American Low Level Jet that delivers moisture to southeastern Sou
72                   The southerly Great Plains low-level jet (GPLLJ) is one of the most significant cir
73 -67 degradation in G1 After cell-cycle exit, low-level Ki-67 expression persisted but was undetectabl
74 nd healing has been accelerated by different low-level laser therapy (LLLT) protocols.
75 ve relaxation, electromyography biofeedback, low-level laser therapy, operant therapy, cognitive beha
76 s to build automated diagnostic models using low-level linguistic features resulting from verbal utte
77 0)Sr and (210)Po in food samples using ultra low-level liquid scintillation counting and alpha-partic
78 s is due to an increasing variability of the low-level monsoon westerlies over the Arabian Sea, drivi
79 ere is skepticism regarding the role of this low-level network in more complex high-level social beha
80 ger cohort of HD cases, including those with low-level neuropathology (Vonsattel grade 0/1).
81 ) release and Ca(2+) influx, which activates low-level nitric oxide production, increases apical memb
82  HIV-1-controllers maintain HIV-1 viremia at low levels (normally <2000 HIV-RNA copies/mL) without an
83 heta, and low-gamma oscillations resumed the low levels observed for intelligible speech.
84   Moreover, we found that hMSCs express very low level of 25(OH)D3-1alpha-hydroxylase (cytochrome P45
85                               Therefore, the low level of adaptation in diverse streams cannot be exp
86 ingle point mutation which results in a very low level of AP activity.
87 unt compared with those samples expressing a low level of Bim.
88 ptide and EGF receptor ligands) maintain the low level of cGMP in the oocyte.
89 d CI are both present but at low levels, the low level of Cro initially stimulates the lytic promoter
90  sensitivity of 7.29nAnM(-)(1)cm(-)(2) and a low level of detection of 70pM.
91 h correlates with CpG islands that display a low level of DNA methylation.
92 ypothesize that the grafted cells produced a low level of dopamine sufficient to cause a levodopa-ind
93 recommendations from moderate, low, and very low level of evidence on the topics of: communication wi
94    The observers were classified as having a low level of experience (<500 scans or <5 y experience w
95                                            A low level of expression of mJHBP in Ae. aegypti larvae s
96  is a common cause of ischemic stroke, and a low level of high-density lipoprotein cholesterol (HDL-C
97 dy, 96 were excluded due to incomplete data, low level of IgA, or poor-quality biopsies.
98                                  There was a low level of intra-observer and inter-observer agreement
99                                          The low level of Kdo-N3 incorporation could be partly explai
100 the adult mammalian myocardium can undergo a low level of new cardiomyocyte renewal of approximately
101 hibiting a medium level of polyphenols and a low level of oleic acid, 'C' and 'D' EVOOs were obtained
102 utant Hsp27 motor neurons is likely to cause low level of oxidative stress, which in turn will contri
103 nursing students (N=256) reported an overall low level of performance in delivering self-management s
104              Clinical features combined with low level of plasma citrulline were highly suggestive of
105                            To circumvent the low level of precursor frequency in patients, we enginee
106 is of a phase 3 randomized clinical trial, a low level of preexisting cytotoxic sTILs predicted the m
107 t of CD8(+)RORgammat(+) T cells expressing a low level of programmed cell death protein 1 and a high
108 erate new nephrons after birth, suggesting a low level of regenerative competence, the tubular epithe
109 vir, and HCV with RAS at amino acid 93 had a low level of resistance to this drug.
110 ry of alcoholism, male sex, impulsivity, and low level of response to alcohol, would predict rate of
111  and provided a possible explanation for the low level of RNA replication observed for the 5'-deleted
112 i-implantitis with high level of concern and low level of therapeutic satisfaction.
113 ne kidney cell monolayers was increased by a low level of uniaxial stretch, which oriented cell divis
114  NIP (all P values <0.001).At the relatively low level of use observed in this trial, interpretive nu
115           Unusual meningococcal strains with low level of virulence similar to carriage strains are m
116             Only the animal group that had a low level of virus-specific CD4(+) T cells in combinatio
117                        It is unknown whether low levels of 1,5-anhydroglucitol (1,5-AG) are associate
118 mecamtiv mecarbil increases contractility at low levels of activation by stabilizing the ON state of
119 e highly repetitive, yet they show extremely low levels of active recombination.
120          These results demonstrate that very low levels of ADP-ribosylation, synthesized by either PA
121 imulated human monocytes released relatively low levels of ATP, whereas cells stimulated with TLR2 ag
122 ontrol of HIV and hepatitis C virus (HCV) is low levels of awareness of infection among key populatio
123           A pufQ deletion strain synthesises low levels of bacteriochlorophyll and accumulates the bi
124 s, we formed groups characterized by high or low levels of BI, as indexed by freezing in response to
125          Performance on held-out data showed low levels of bias and high Pearson correlation coeffici
126 vated cytolytic toxicity in combination with low levels of biofilm formation was predictive of an inc
127  investment, especially for populations with low levels of built capital.Globally diarrheal disease t
128 igh plasma Bb levels, six (40%) patients had low levels of C3, and nine (60%) patients had high level
129 og-rank test showed that ccRCC patients with low levels of CA9 promoter methylation had a higher surv
130 gly, supplementation of cyr1Delta cells with low levels of cAMP enabled them to form hyphae in respon
131 onditioned media-derived IFN-gamma exhibited low levels of Cathepsin K, TRAP, RANK, and tumor necrosi
132 g carbonic anhydrase type II, but relatively low levels of cathepsin K.
133  cellular immune responses while maintaining low levels of CD4(+) T-cell activation to avoid the gene
134         Through this analysis, we found that low levels of chitinase activity are sufficient for natu
135 gh the bread supplemented with PCs contained low levels of CML, this process may adversely affect bre
136                                   Conclusion Low levels of CNS leukemia, regardless of RBCs, predict
137 FDG uptake identified subjects with high and low levels of cold-activated BAT mass (high BAT, 96 +/-
138                                              Low levels of CP accumulated in vivo in the absence of d
139                                              Low levels of cross-reactivity between the H3N2v and sH3
140       Furthermore, cells with pathologically low levels of cytoplasmic RNA are detected earlier and i
141 is of networks with either very high or very low levels of degree heterogeneity.
142                                              Low levels of DII-specific fluorescence corresponding to
143            We find that diffusion is slow at low levels of disorder, while higher disorder allows for
144 low soil nutrient availability and long-term low levels of disturbance may help to account for the lo
145 on, MTA1 overexpression correlates well with low levels of DNMT3a which, in turn also correlates with
146 lder form of X-linked HED (XLHED), contained low levels of EDA capable of binding to EDAR.
147 ts contained either background EDA levels or low levels of EDA that could not bind to recombinant EDA
148 o recurrence than those whose tumors express low levels of either alone suggesting similar stromal si
149  healing of diabetic wounds is attributed to low levels of endogenous growth factors, including vascu
150 Hac1(i) Phosphorylation site mutants survive low levels of endoplasmic reticulum stress better than I
151                High levels of ERBB2/HER2 and low levels of ESR1 were associated with pCR in all treat
152 ly, we demonstrated that chronic exposure to low levels of estradiol-17beta (E2) increases mean arter
153  generation of CD133(hi) CSCs that expressed low levels of estrogen receptor alpha.
154 jority of this protective effect occurred at low levels of exercise and was observed regardless of in
155                 The combination of a PAM and low levels of exogenous GABA further increased human isl
156 ntal question is whether these comparatively low levels of expression can successfully satisfy the st
157 ex 2 repressed the IRAK-M promoter, allowing low levels of expression; following LPS stimulation, the
158           Furthermore, imaging revealed only low levels of F-Dapa in the urinary bladder, even after
159 lmost all major brain areas contain high and low levels of FMRP cell groups adjacent to each other or
160                                    Extremely low levels of gadolinium are found in juvenile macaque t
161                                   Conclusion Low levels of gadolinium are present in the brain after
162 deletion of mir-7a2 causes infertility, with low levels of gonadotropic and sex steroid hormones, sma
163 anaerobically grown bacteria were exposed to low levels of H2O2 or incubated in seawater.
164 ed enhancer signature, involving H3K4me1 and low levels of H3K27ac, has been reported to mark inactiv
165 the mosquito correlates with the presence of low levels of H3K9me3 at the binding site for the PF3D7_
166          Moreover, we developed a model that low levels of HBsAg, HBcAb, and albumin and high fibrosi
167 owever, this population typically engages in low levels of health-promoting physical activity compare
168 kout (MAT1A-KO) mice, which have chronically low levels of hepatic S-adenosylmethionine (SAMe) and sp
169  that individuals over 90 years old carried low levels of heteroplasmic variants in their genomes.
170                                              Low levels of HMPV are rarely detected in healthy childr
171 lls from transgenic swine expressing high or low levels of human CD47 were infused into conditioned b
172 er of differentiation 38 (CD38) and CD69 but low levels of human leukocyte antigen DR, CD80, and CD86
173                             We conclude that low levels of IFN-I signaling contribute to HIV-1-associ
174 s, similar levels of binding IgG antibodies, low levels of IgA antibodies, and high levels of antibod
175                        Despite comparatively low levels of infection, primary amoebic meningoencephal
176 vision and apoptosis) can function with such low levels of information transfer.
177                During range expansions, even low levels of interbreeding can lead to massive introgre
178 arker Syglec-F, variable levels of CCR3, and low levels of interleukin-5Ralpha.
179                Results indicate that keeping low levels of intracellular lipid is crucial for mitocho
180 marily promotes axon survival by maintaining low levels of its substrate NMN rather than generating N
181 ure of human complex traits, where SNPs with low levels of LD (LLD) have larger per-SNP heritability.
182 e U.S.-based prebirth cohort with relatively low levels of lead exposure.
183                                   Generally, low levels of legacy flame retardants compared to their
184  EBV induces rapid B cell proliferation with low levels of LMP1 and little apoptosis.
185  have led to concern that these drugs or the low levels of low-density lipoprotein (LDL) cholesterol
186  cell lines exhibiting EMT markers expressed low levels of MHC-I, high levels of PD-L1, and contained
187 m healthy subjects express functional BLT-1, low levels of minimally functional ERV-1, and inversed c
188   Intestinal inflammation is associated with low levels of mucosal ATP, highlighting the importance o
189 put induced by drugs and in cells expressing low levels of myosin-binding protein C.
190                                   Relatively low levels of N-glycans are found on transmembrane mucin
191                        Despite inducing very low levels of nAb, H7 vaccines conferred complete protec
192 w IFN-gamma and TNF-alpha responses and have low levels of NK cells and CD4(+) and CD8(+) T cells com
193 ude that for sample/target combinations with low levels of nucleic acids (Cq >/= 29) and/or variable
194  signaling to a greater extent in cells with low levels of ongoing Wnt signaling, suggesting that cel
195                                  Exposure to low levels of oxidants or genetic inhibition of glycogen
196 erpesvirus (i) whether nestlings with either low levels of oxidative damage or high levels of antioxi
197 af1 show marked elongation defects, although low levels of Paf1 on Pol2 are sufficient for transcript
198 undant vascular amyloid, in association with low levels of parenchymal amyloid deposits.
199 a cell lines expressed high levels of MHC-I, low levels of PD-L1, and contained within their stroma C
200 y virus (SHIV) model is associated with very low levels of persistent viraemia, which leads to the es
201 ng contributes to oxidative damage caused by low levels of PGC1A in liver, exacerbating steatohepatit
202                Unhealthful dietary patterns, low levels of physical activity, and high sedentary time
203   Pseudomonas cells arrive at a surface with low levels of piliation and TFP activity, which both pro
204 n in proliferating myoblasts is prevented by low levels of PJA1, its cytoplasmic localization and the
205  ANGPTL3, encoding angiopoietin-like 3, with low levels of plasma lipoproteins.
206 or the classification of lavender honey with low levels of pollen since this technique agrees well wi
207 ing, but epigenome-wide methylation data for low levels of prenatal lead exposure are lacking.
208 by a Mex3a expression program and relatively low levels of proliferation genes.
209 dictions change in a multi-host system, with low levels of recombination, consistent with real r/m es
210  In the first, risk was predicted jointly by low levels of SA and high levels of FCA-that is a level
211 amides, and oxidized fatty acids, as well as low levels of SAMe and downstream metabolites.
212 odevices has not been thoroughly used due to low levels of sensitivity in measurements.
213  However, they detected villous atrophy with low levels of sensitivity: 0.50 for the tTG IgA assay (9
214  cord, in the chronically repaired cord only low levels of serotonergic axons regenerated into the gr
215 strains are egg laying-defective and contain low levels of serotonin (5-HT) and high levels of the 5-
216                    In addition to exhibiting low levels of sialylation, GNE-deficient cells produced
217             Inflammation was associated with low levels of SIV RNA in the brain as shown by in situ h
218 phenotypes are present in animals expressing low levels of SMN, indicating that both proteins functio
219 uron development and motor defects caused by low levels of SMN.
220         A low SO2 consumption is favoured by low levels of SO2, by a low availability of free SO2 cau
221 re of cortisol response showed that high and low levels of stress-induced cortisol release correlated
222  (area under the curve) showed that high and low levels of stress-induced cortisol release were assoc
223  in ineffective (nifH) nodules, particularly low levels of sucrose were observed, suggesting that pla
224                         Considering the very low levels of sugars detected, authentic PDO Grana Padan
225 ears; n=39 at young adulthood) had similarly low levels of symptoms across most ages and outcomes.
226                                              Low levels of TA were detected in 36% of the samples col
227            Natural hosts of SIV express very low levels of the canonical entry coreceptor CCR5, and r
228  CsGABAA beta, CsGluCl1 and CspHCl, but very low levels of the CsGABArdl or CsnACh subunits.
229 rt time-to-progression (<2 years) had either low levels of the dual-stained cells or high levels of s
230 ly isolated mouse and human NK cells express low levels of the endo-beta-D-glucuronidase heparanase t
231 e cells in patients' tumors characterized by low levels of the proapoptotic molecule p53-upregulated
232                             SMA is caused by low levels of the survival motor neuron (SMN) protein.
233 often fatal neuromuscular disorder caused by low levels of the Survival Motor Neuron (SMN) protein.
234 ying that any combination of high, medium or low levels of these traits can be found across rice geno
235                                           At low levels of Torso, similar to those present in the emb
236 acids and esters require materials with very low levels of transition metal contamination.
237 n former cold-insensitive neurons expressing low levels of TRPM8-like current.
238 gh specificity and sensitivity for detecting low levels of tumor cell death (2%-5%).
239 with combined antiretroviral therapy (cART), low levels of type I interferon (IFN-I) signaling persis
240                   There is concern that even low levels of viremia can result in CZS, meaning an effe
241                                              Low levels of virion CMV DNA were found in 10 of 103 (9.
242 in PRRSV-infected pigs are delayed onset and low levels of virus neutralizing antibodies, as well as
243 ther, these data support our hypothesis that low levels of vitamin A actively promote GI GVHD and are
244                                              Low levels of vitamin D also appear to be a risk factor
245      Drylands are characterized by extremely low levels of water and nutrients and exhibit highly het
246 the gene encoding serine protease inhibitor, low levels of which are associated with alpha-1 antitryp
247 ment through the detection and punishment of low-level offending or violation behavior.
248 ltiple myeloma (MM) cells, and at relatively low levels on normal lymphoid and myeloid cells, and in
249  organisms to survive drying, is detected at low levels or not at all in some tardigrade species, ind
250       We consistently detected self-limited, low-level oral CMV shedding events, which we termed tran
251 on; however, these tests often miss cases of low-level parasitemia, and PfHRP-II tests can give false
252                        Long-term exposure to low levels (PELs </=0.05 mg/m3, </=0.10 mg/m3, or </=0.3
253              These findings may help uncover low-level perceptual mechanisms underlying delusional be
254 uten-free or ATI-free diet and in mice given low-level polyinosinic:polycytidylic acid or dextran sod
255 ng in the boundary layer that contributed to low level positive potential vorticity.
256 ge, have deficits in connectivity related to low-level processing, which contribute to a developmenta
257                                  We observed low-level productive infection on exposure of these cell
258 rambled images is that they contain the same low-level properties as the intact objects, but lack the
259 that the domain locations are constrained by low-level properties such as end-stopping, eccentricity,
260 2 promote transcript nuclear export, whereas low levels reflect nuclear retention.
261  noteworthy binding characters make possible low level removal of Hg(2+) ions.
262 al cutoff point for depletion efficacy, with low-level residual NK cells providing sufficient help to
263 for precentral gyrus, which represented only low-level rule information.
264  from 6 months onward in regions involved in low-level sensory processing.
265                                           As low-level, sensory processing impacts higher-order opera
266 administrations with poly-ICLC increased the low-level serum anti-Env IgG responses elicited by NYVAC
267                                              Low-level silica exposure was defined as having a lifeti
268 dence for a dynamic neural transformation of low-level speech features as they propagate along the au
269                        Our results show that low-level speech features propagate throughout the peris
270 s showed tuning of the perisylvian cortex to low-level speech features.
271 tions from different atmospheric models that low-level sublimation accounts for a 17% reduction of to
272  show that this dry air leads to significant low-level sublimation of snowfall.
273                                      Because low-level sustained microglia activation can lead to abn
274  performs optimally among those with initial low-level symptoms.
275 that when Cro and CI are both present but at low levels, the low level of Cro initially stimulates th
276 anscription pattern is largely retained at a low level through mitosis, whereas the amplitude of tran
277 r sensitivity of E. verrucosus to persisting low-level toxicant pressure.
278                   We observed heterogeneous, low-level transfection of the collecting duct, proximal
279                         RAGE is expressed at low levels under normal physiology, but it is highly upr
280                  However, we identified many low-level variants (<5%) distributed across the 5' UTR a
281 -time post-week 24 was spent with persistent low-level viraemia (80-5,000 copies/ml) and 10% with VL
282                 Strategies for management of low-level viraemia need to be incorporated into WHO guid
283                                              Low-level viraemia occurred in 16 013 (23%) of 69 454 pa
284                                              Low-level viraemia was associated with increased hazards
285                                              Low-level viraemia was defined as the occurrence of at l
286 urther with higher ranges and persistence of low-level viraemia.
287 orming a sanctuary site for latent virus and low-level viral replication in the absence of neuro-dise
288 ir persistence include replenishment through low-level viral replication, longevity and homeostatic p
289  million input cells/mouse) experienced very low level viremia (201 copies/mL); sequence confirmation
290 ategy for LT recipients with undetectable or low-level viremia at time of LT.
291 idence of a prolonged period of intermittent low-level viremia.
292 istance aftereffects are similar to those of low-level visual aftereffects, supporting the idea that
293 r") is primarily used to "tag" processing of low-level visual and high-level cognitive phenomena.
294 evels of visual analysis, incorporating both low-level visual features and high-level social informat
295 ctions is not easily explainable in terms of low-level visual features, attention, or the animacy, ac
296 , driven by an increasing variability of the low-level westerlies over the Arabian Sea.
297 sity lipoprotein cholesterol (LDL-C) to very low levels when added to background lipid-lowering thera
298 ssure deficit is highly predictable from the low-level wind field via gradient wind balance.
299 roduce anomalous surface-air temperature and low-level wind fields in the two polar regions that cont
300 PTA, and plasma levels of paclitaxel fall to low levels within 1 hour.

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