ライフサイエンスコーパス: low yield

1 grape-based compost, but this coincided with low yield.

2 activated alkenes have typically occurred in low yield.

3 24 followed by lactone formation gave 26 in low yield.

4 2) followed by lactonization gave 26 also in low yield.

5 omer with the desired stereochemistry but in low yield.

6 proach is that it is both time-consuming and low yield.

7 culture was less sensitive and had extremely low yield.

8 4)(O(t)Bu)(12)Cl][U(CH(2)SiMe(3))(5)] (1) in low yield.

9 e conditions, protracted differentiation and low yield.

10 binding using a Ni column with a relatively low yield.

11 using potassium t-butoxide gave isoprene in low yield.

12 eld, whereas the CB[5] analogue is formed in low yield.

13 H(2)O to give the copper porphyrin albeit in low yield.

14 ines containing -CH(2)OR groups proceeded in low yield.

15 l testing for these specific mutations is of low yield.

16 e-induced cleavage was observed, although at low yield.

17 al other monomeric products were obtained in low yield.

18 onged monitoring and are limited by cost and low yield.

19 versial in this population given the overall low yield.

20 oes not perform well in this setting and has low yield.

21 lls are technically demanding and relatively low-yield.

22 ligand are cumbersome and typically lead to low yields.

23 d the desired products are often produced in low yields.

24 es to provide ortho-(alkyltelluro)phenols in low yields.

25 sulfur that have previously been reported in low yields.

26 irconium methodology is effective, albeit in low yields.

27 ide poor and random cell contact, leading to low yields.

28 carbamoyl allenes, while the acetates afford low yields.

29 r RNAs, into cell-secreted exosomes leads to low yields.

30 nificantly larger 45-nm particles, albeit in low yields.

31 ds, while "grafting to" approaches result in low yields.

32 sslinked to TnC, TnT and actin, but all with low yields.

33 ), but this can be very labor-intensive with low yields.

34 cNDs require multiple steps and suffer from low yields.

35 lved by omitting libraries with particularly low yields.

36 most desirable ones are biosynthesized with low yields.

37 requiring numerous stepwise procedures with low yields.

38 lcNAc) oligosaccharides usually suffers from low yields.

39 recovery of terpenes from plants because of low yields.

40 favorable amino acids or with prohibitively low yields.

41 rted, the procedures are relatively long and low yielding.

42 on is challenging since direct reactions are low yielding.

43 use their synthesis is challenging and often low-yielding.

44 relatively slow, inefficient, and frequently low-yielding.

45 ed the test inappropriately with a resulting low yield (0.47%) of CRC diagnosis.

46 -confined dipole variation associated with a low-yield (13-14%) trans-cis isomerization of the azoben

47 ar conditions afford the carbocycles in very low yields (2% and 6%, respectively).

48 31-73%); cyclic aliphatic substrates provide low yields (24-38%).

49 in the region could be classified as stable low yield, 28% as unstable (low yield some years, high o

50 also suffer from limited processability with low yield (2D film or beads) and high fabrication cost (

51 anded clusters were detected, albeit at very low yields (37 Fpg-OxyPurine clusters Gbp(-1) kJ(-1) m(2

52 e protected cyclotetrasyringyl derivative in low yield (7%), which was fully characterized by (1)H NM

53 anediamine with dimethyldioxirane, albeit in low yield (7%).

54 es of tumours, its specificity is relatively low, yielding a moderate diagnostic performance.

55 It provides the adducts in low yields accompanied by complex mixtures of secondary

56 edure is simple, it provides 3 in relatively low yield, accompanied by a smaller amount of the isomer

57 is of Boc- or Cbz-D-Hyv lactone proceeded in low yield; additionally, the lactones are too unreactive

58 disturbance, however, could be resilient to low-yield agriculture and thus fare better under land sh

59 where, more than any other tropical country, low-yielding agriculture has been replaced by intensive

60 tuent at the 5-position typically results in low yield and a mixture of porphyrin products derived fr

61 anical exfoliation and transfer suffers from low yield and ambient corrosion problem and now is facin

62 xplosive mixtures, but they suffer from very low yield and are intrinsically limited to small volumes

63 Enterobacter cloacae SLD1a-1 is purified in low yield and has relatively low activity in the pure fo

64 The low yield and high cost of endoscopic screening of patie

65 vailable from a yeast system with relatively low yield and high cost, which has made it difficult to

66 However, a significant barrier has been the low yield and high protein content of phototrophic bioma

67 ss II I-A molecules have been limited by the low yield and instability of soluble, recombinant hetero

68 e (3-Cl-Tyr), although 3-Cl-Tyr is formed at low yield and is subject to metabolism.

69 ture of benzene and toluene, all with rather low yield and leading to compounds with similar chemical

70 d size with an increased length/width ratio, low yield and less starch content in the early storage r

71 mouse HSC isolation is commonly hampered by low yield and purity.

72 mplex analytic approaches that generate very low yield and purity.

73 in 4 weeks of a prior negative result was of low yield and rarely generated a positive result conside

74 The sol-gel process presented a low yield and resulted in a liquid product without stabi

75 is frequently complicated by the problems of low yield and specificity, especially when the GC conten

76 nthesis lengths, high synthesis error rates, low yield and the challenges of assembling long construc

77 holangiography is discouraged in view of its low yield and the significant rate of false positive cho

78 I3K isoforms in insect cells has resulted in low yield and variable activity, limiting biophysical an

79 ely damaging to the environment, making them low yield and very expensive.

80 ow seeding densities; however, this leads to low yield and viability.

81 DIs are generally lengthy, nonselective, and low yielding and their polymeric analogues have yet to b

82 formationally rigid precursors and are often low yielding and/or non-stereoselective.

83 of pteroyl-gamma-glutamate-cysteine provide low yields and are not easily reproducible.

84 proteins in plants is limited by relatively low yields and difficulties in extraction and purificati

85 this antigen is that it is produced only at low yields and does not have a homogeneous composition.

86 d to catalyze asymmetric Michael addition in low yields and ee, but activation with fluoride leads to

87 rom FFPE specimens is challenging because of low yields and high amounts of degradation.

88 approaches rely on multi-step ligations with low yields and incomplete products.

89 To address low yields and low income both, the soil fertility, the

90 ous catalysts at high temperatures, but with low yields and low selectivity.

91 fforded the desired cyclopropane products in low yields and poor enantioselectivity.

92 use of undercooled metals, primarily due to low yields and poor stability.

93 ycyclic cores have proven challenging due to low yields and poor stereoselectivity.

94 in biosynthesis has long been constrained by low yields and poorly understood bottlenecks.

95 phthalene and dihydronaphthalene substrates, low yields and product mixtures have reduced the impact

96 However, low yields and purity of the native proteasome have hind

97 into acrylates are reversible and result in low yields and radical dimerization.

98 With conventional ligation procedures low yields and random orientation of oligomers makes clo

99 cals is the major goal of biorefineries, but low yields and selectivity for fuel precursors such as s

100 nts in vitro as reflected by their extremely low yields and shortened lengths upon isolation.

101 multistep syntheses, which also suffer from low yields and/or poor precursor scopes.

102 ally, the GC-rich STR DNA sequences generate low-yield and heterogeneous products when amplified via

103 op-down method is time-consuming, costly and low-yield and it produces fragmented nanosheets with sub

104 Low-yielding and moderately alpha- and diastereoselectiv

105 hemical method addresses this challenge in a low-yielding and not fully understood fashion: Schonecke

106 cytosolic delivery, poor target-specificity, low yield, and inconsistency in production.

107 development are limited by poor solubility, low yield, and protein misfolding.

108 Synthesis, however, proceeds with low yields, and derivatives are difficult to prepare.

109 e specialized substrates, bulky fusion tags, low yields, and extra purification steps to achieve the

110 such as the poor availability of precursors, low yields, and use and production of undesirable substa

111 tes that are typically prepared via tedious, low-yield approaches.

112 mary amine side chain of lysine demonstrated low yields ( approximately 0.2%) of chloropicrin, but hi

113 stereomeric mixtures ( approximately 2:1) in low yields ( approximately 40%).

114 NUE varied from 48% in stable low yield areas to 88% in stable high yield areas.

115 64-1.67) Tg N y(-1) from stable and unstable low yield areas, corresponding to USD 485 (267-702) mill

116 led several largely converted yet relatively low-yielding areas (such as central, eastern, and northe

117 mland can allow the abandonment (sparing) of low-yielding areas that subsequently recover as secondar

118 -deficient substrates afford product in very low yields at room temperature, but moderate to good yie

119 We find that forest recovery is superior to low-yielding biofuel production scenarios such as oil pa

120 In syndromes where blood cultures are low-yield, blood cultures can be considered for patients

121 ion, a laborious process that often leads to low yield both in the amount of DNA and the fraction of

122 of tetraphenylbenzyne, has been prepared in low yield by diazotization of 3,4,5,6-tetraphenylanthran

123 d by enzymatic reduction of 5-FU and in very low yield by hydrogenation of 5-FU; however, a practical

124 iopharmaceuticals that can be made only with low yields by currently available equipment.

125 enium ion 1c, but they are generated in very low yields (ca. 10%) so it is not possible to definitive

126 imine) carbamates, especially for previously low-yielding carbamates containing pai-functionality.

127 erally problematic and frequently results in low yield, cell toxicity, protein aggregation and misfol

128 ed pluripotent stem cells (hiPSCs) result in low yields, cellular heterogeneity, and limited scalabil

129 -nitrosamines in inhaled smoke from filtered low-yield cigarettes.

130 Further, low-yielding combinations could be rapidly optimized wit

131 r of screenings, although all strategies had low yield compared with the implantable loop recorder.

132 Co-transfections of high- and low-yielding constructs demonstrated that under conditio

133 ntation of D-dimer based protocols to reduce low-yield CTPA ordering.

134 Compared to a low-yielding cultivar, a high-yielding cultivar signific

135 rced by extraction and purification from the low-yielding daffodil Narcissus pseudonarcissus.

136 ystem was implemented: Examinations that had low-yield decision support scores could not be scheduled

137 The fraction of low-yield (decision support score, 1-3) examinations req

138 Low-yielding, deep bedrock wells may require large contr

139 Although the initial system suffered from low yields, deleting redundant copies of tRNA(fMet) from

140 disease pressure during the growing season, low yield differences between treatments resulted in neg

141 ays using DNA origami typically suffers from low yield due to inefficient QD and QR DNA functionaliza

142 ethods, but such approaches typically have a low yield due to inhomogeneous oxidation.

143 toward one another could only be obtained in low yields due to a combination of stability and steric

144 lution coupling in aqueous medium results in low yields due to the solvent incompatibility of DNA and

145 ments, high variability in loading rates and low yields during loading are barriers to efficient DE F

146 solubility in aqueous solvents and generally low yields during purification and expression.

147 e find an increased likelihood of concurrent low yields during summers featuring meandering jets in o

148 the relative yield reductions are larger in low-yielding environments (e.g., high reference temperat

149 are now well-defined criteria for rejecting low-yield ETAs from adults, but it is uncertain whether

150 RNAs, including aptamers, ribozymes, and, in low yield, even tRNA.

151 ers, as endomyocardial biopsy has relatively low yield, even with directed electrophysiological mappi

152 ll women in the HMO aged 50-64 years) and of low-yield examinations (ie, sinus, rib, and skull radiog

153 rld's supply chain for vinblastine relies on low-yielding extraction and purification of the precurso

154 port crop production (i.e. reconstruction of low yield farmland, and agricultural subsidies), combine

155 y material, as its synthesis requires both a low-yielding fermentation process using a pathogenic org

156 ld close 63% of yield gaps between high- and low-yielding fields.

157 y clinical exome sequencing, with relatively low yield for cardiovascular abnormalities.

158 ficult to purify, and this caused an overall low yield for the synthesis.

159 d pyrrolidine than a 2-lithiated piperidine; low yields for the lithiation-substitution of N-Boc-2-ph

160 The low-yield formation of nC(60) from organic solvent solut

161 This complex is formed in low yield from [Ir(COD)(OMe)](2), dtbpy, COE, and B(2)pi

162 ultiple, high infusion doses, the relatively low yield from peripheral blood-sourced MDSCs (PB-MDSCs)

163 A second species can be isolated in low yield from the reaction mixtures of 1, namely [Li(OE

164 ligate chaperone of PDE6 and that it enables low yield functional folding of cone PDE6C in cultured c

165 ported in vivo assembly techniques have been low yielding, generating only tens to hundreds of constr

166 in hypoxic tumor regions are constrained by low-yielding glycolysis, and any means of reducing the c

167 Cases with very low yield have decreased substantially over time, 6.8% a

168 Low yield, high aggregation, and poor stability of recom

169 tions from high-yield/low-price fisheries to low-yield/high-price fisheries, generating severe strain

170 tively selecting parents to produce high- or low-yield hybrids.

171 Because standard imaging has a low yield identifying potential recurrence, blind (131)I

172 esulted in a substantially decreased rate of low-yield imaging examinations and a markedly increased

173 mia before emergency department discharge is low yield in patients with negative troponins and TIMI s

174 erihepatic lymph nodes will therefore have a low yield in patients without some evidence of disease o

175 e pre-employment TB screening program was of low yield in the detection of active TB or increased LTB

176 al culture in terms of time requirements and low yield in the setting of prior antibiotic administrat

177 al culture in terms of time requirements and low yield in the setting of prior antibiotic administrat

178 ower S states, which are probably present in low yield in these samples.

179 Because of its low yield in unselected specimens, stool culture is ofte

180 Their synthesis has been complicated by low yields in solid-phase syntheses.

181 entified oxidation products were observed in low yields in the oxidations.

182 The less reactive diazoacetamides give very low yields in their reactions with benzhydryl imines but

183 ene cycloadduct could be detected, albeit in low yield, in the photolysate.

184 fficult coupling partners that often deliver low yields, in particular in reactions with aryl amines.

185 dary antibodies or antigens often results in low yields, indeterminant stoichiometry, reduced target

186 nd 2-acylated furans are obtained, albeit in low yield, instead of nitroalkanols.

187 ction, originally occurring spontaneously in low yields, into a practical methodology.

188 ted technologies for new neuron subtypes are low yield, involving intensive transgenic strain or viru

189 Islet culture enables pooling of multiple low-yield isolations into an effective islet mass, but i

190 the Z-delta isomer is initially produced in low yield, it is continually reformed via decomposition

191 he art suffers from limited substrate scope, low yields, long reaction times, and anomeric mixtures.

192 art methods include limited substrate scope, low yields, long reaction times, and anomeric mixtures.

193 a few (four) instances and has proceeded in low yield (</=6%).

194 Cases with very low yield (<2000 IEQ/g or IEQ/kg) have decreased substan

195 of these hybrid materials have relied on the low-yield manual exfoliation and stacking of individual

196 vely been purified using difficult-to-scale, low-yield methodologies such as affinity and size-exclus

197 oxorubicin derivatives were isolated in very low yield, most likely because of the inherent base labi

198 ts suffer from a reliance on complicated and low-yielding multistep organic syntheses that dramatical

199 tion, which is responsible for the extremely low yields observed for the incorporation of the North p

200 tenoid beta1-ring in picoseconds occurs at a low yield of <1%, whereby the beta1-ring retains a trans

201 through dismutation reaction, resulting in a low yield of (1)O(2) detected.

202 azolone (20) at 600 degrees C affords only a low yield of azabutadiene (18) due to chemically activat

203 yl radical with O(2) in benzene results in a low yield of benzene oxide, which is shown by isotopic l

204 ceration, grinding or pressing have reported low yield of betalains and required large volume of solv

205 The low yield of cross-sectional imaging performed for evalu

206 because of lack of comprehensive studies and low yield of diagnostic approach.

207 The low yield of dissociation products from the aromatic PhB

208 clones, but an important disadvantage is the low yield of DNA, both for vectors alone and when carryi

209 nificantly contributing to the high cost and low yield of drug discovery.

210 e in making the diagnosis, partly due to the low yield of endomyocardial biopsy in cardiac sarcoidosi

211 ly deleted in this region resulted in a very low yield of H37-expressing clones.

212 However, this assay results in a low yield of high-quality data, defined as the complete

213 The underlying reason for the low yield of high-quality material is that CZT suffers f

214 bility occurring after assignment, and (c) a low yield of information for explaining why certain effe

215 The low yield of isoprenoids in plants makes them difficult

216 While a low yield of long-lived electrons limits the hydrogen ev

217 0(-7) mbar) source, good chemical stability, low yield of matrix-related ions, low matrix consumption

218 hypothesized that a potential reason for the low yield of mouse BMSCs is the flushing of the marrow u

219 owever, DRG derived from mouse or rat give a low yield of neurons, and they are difficult to culture.

220 ins derived from other ketones resulted in a low yield of phlorin from acetophenone (5%) and no detec

221 to coat protein, there is a correspondingly low yield of proper procapsids.

222 Unfortunately, the low yield of Rdh54 from the yeast expression system has

223 The low yield of screening colonoscopy in this age group is

224 nderwent silylation in good yield, whereas a low yield of siloxane was obtained from 2-bromofuran, an

225 Because of the low yield of the baculovirus system, the E. coli-express

226 The reasons for the relatively low yield of the H5N1 strains are not fully understood,

227 DM2/p53 inhibitor AM-8553 was impeded by the low yield of the initial synthesis.

228 A low yield of the platinum(II) complex could also be isol

229 Despite the low yield of the ROS, jack bean urease was shown to be i

230 gain gave mainly triazole together with very low yields of 1-(1,2,4-triazol-1-yl)-2,4,6-trimethylbenz

231 The trisubstituted epoxide gave low yields of adducts with all (2-pyridyl)methyllithium

232 ative iron(-I) complex with weak acids gives low yields of ammonia and hydrazine, demonstrating that

233 Bu(3)SnH reduces DMF, but along with the low yields of Bu(3)SnOSnBu(3) (but no Bu(3)SnOCH(2)NMe(2

234 se of the land constraint, the intrinsically low yields of energy per unit of land area, and rapid te

235 neurons is hindered by the long duration and low yields of existing protocols for in vitro differenti

236 ell differentiation protocols are limited by low yields of hematopoietic progeny.

237 This paradox could explain the low yields of hemochromatosis screening reported by some

238 g hydroxy fatty acids (HFA) have resulted in low yields of HFA compared with the native castor (Ricin

239 ies in human mast cells has been hampered by low yields of human mast cell cultures and their poor tr

240 en lead to modification, degradation, and/or low yields of lignin.

241 Low yields of photoproducts, namely pyrimidine dimers, a

242 aterial, and labor resources while providing low yields of products.

243 nation of rAAV with the Ad helper virus, (2) low yields of rAAV and (3) production of replication-com

244 simulated vent structures appear to generate low yields of simple organics.

245 roduced mainly difluoro products (8h-k) with low yields of tertrafluoro derivatives (9h-k).

246 ntiation result in mixed cell populations or low yields of the cells of interest.

247 Such transitions happen rarely, resulting in low yields of the photocatalytic water splitting observe

248 ation and IC(50) against ACE was determined, low yields of YAN from TML did not explain adequately th

249 arative analysis between high-, medium-, and low-yielding oil palms, particularly during fruit develo

250 ctrosynthesis of thinner walled CNTs, but at low yield (only ~ 15% of the product are CNTs).

251 ols such as screening tracers with initially low yield or labeling efficiency, imaging low receptor d

252 short read length, high input requirements, low yield or long protocols.

253 ompound have been reported, which are either low yielding or long (13 or more steps).

254 yl halides, but these organisms produce very low yields or are not amenable to industrial production.

255 etic methods to these structures suffer from low yields or operational disadvantages.

256 ; however, these procedures either result in low yields or require numerous sequential reactions and

257 r pumping, e.g., in groundwater wells with a low yield, or in long-term time series, in which short-t

258 unt of product obtainable from traditionally low-yielding organic reactions.

259 entration) characterized by rapid growth and low yield, our highly concentrated NP system supplies re

260 Copying is low-yielding, particularly for long RNA.

261 hway shows lower protein efficiency than the low-yield pathway.

262 e further decomposed into a high-yield and a low-yield pathway.

263 Low yields, poor stability, and inefficient binding to c

264 efforts should focus on reducing testing in low-yield populations given the high costs of mNGS relat

265 l of prebiotic synthesis, in contrast to the low yields previously obtained under more dilute conditi

266 o predefined features, which are necessarily low-yield processes and which can introduce undesirable

267 ng capacity of the vector, which resulted in low-yield production; in addition, further analyses in W

268 This low yield prompted us to perform a more quantitative ass

269 etrating peptides for instance) provide very low yields: QDs stay at the plasma membrane or are trapp

270 so afford carbaporphyrin products, albeit in low yields ranging from 5 to 8%.

271 However, their high cost and low yield remain open challenges for practical applicati

272 intermediate Baccatin III, however the very low yields remain a hinderance to their commercial utili

273 of primary carbons was feasible but afforded low yields, requiring ClCH(2)CO(2)H instead of InCl(3).H

274 hindered by syntheses that are traditionally low-yielding, requiring long reaction times, laborious p

275 ublication bias: unsuccessful experiments or low-yielding results are rarely reported.

276 technical advances in sample preparation for low-yield sample inputs and a computational pipeline for

277 In conclusion, rejecting specimens of proven low yield saves reagent costs and, more importantly, sav

278 In conclusion, EMB was found to be a low-yield screening modality for rejection beyond 6 mont

279 -yielding season but less rapidly during the low-yielding season if observed temperature and radiatio

280 A fermentation method that bypasses the low-yielding semisynthesis of epirubicin (4'-epidoxorubi

281 sified as stable low yield, 28% as unstable (low yield some years, high others), and 46% as stable hi

282 hown to be extremely brittle and demonstrate low yield strength.

283 At low yield strengths, microstructure greatly influenced t

284 with fewer gaps, concerns about error rates, low yields, stringent DNA requirements and uncertainty a

285 yclic architectures that require lengthy and low-yielding syntheses; for example, one glucose-selecti

286 y expressed in plants with heated shoots and low yield that had been previously associated with flowe

287 ation is a random process and suffers from a low yield that is unable to fulfill the high-throughput

288 ods typically afford ill-defined products in low yields (that is, less than 10-20wt%).

289 In spite of its low yield, the UDP-Galf is readily purified from startin

290 a water extraction step) or is too slow and low-yielding to be practical.

291 ides and dialkylalkynes normally afford only low yields under our standard reaction conditions.

292 ulty associated with crystallization such as low yield, unsuitability for large-scale synthesis, etc.

293 , extreme reaction conditions, and sometimes low yields using traditional stepwise synthetic methods.

294 ed bases, abasic sites, and strand breaks at low yields, we tested whether it also produces clusters

295 products 42 and 43 were obtained, albeit in low yield, when bulky ethyl and isopropyl groups were em

296 rmers' varieties characterized by inherently low yield which is compounded by generally high suscepti

297 d that myocardial perfusion imaging would be low yield with limited short-term value and that early r

298 yield with secondary amines, and moderate-to-low yield with primary amines.

299 eactions that gave either no product or very low yields with the corresponding less electrophilic N-t

300 ined when clinicians suspect sepsis, yet are low-yield with a false-positive rate up to 50%.