ライフサイエンスコーパス: luminal

1 Post-treatment residual disease was largely luminal A (69%).

2 h the retrospective and prospective cohorts: luminal A (retrospective, 538 [34.3%]; prospective, 737

3 ed that AGTR1 overexpression occurred in the luminal A and B subtypes of breast cancer, was mutually

4 luminal B tumors, whereas in 14.3% of cases luminal A and B tumors converted to HER2-E tumors.

5 classified in so-called intrinsic subtypes (luminal A and B, HER2-enriched, basal-like, and normal-l

6 rapy for younger patients with tumors of the luminal A and basal molecular subtypes.

7 eration and viability of TNBC cells, but not Luminal A cells, and (3) is associated with a poor progn

8 s, which relate to estrogen receptor (ER)(+) luminal A or luminal B and ER(-) basal-like cancers and

9 RFS, 39%; DMFS, 73%; PCSS, 86%; OS, 80%) and luminal A prostate cancers (10-year bRFS, 41%; DMFS, 73%

10 ; P = .027) breast cancer subtypes, with the Luminal A subtype as the reference.

11 i-67 response was observed for pictilisib in luminal A tumors (1.01; P = .98).

12 In 40.2% of cases, luminal A tumors converted to luminal B tumors, whereas

13 ors, 30.0% in luminal B tumors, and 55.3% in luminal A tumors.

14 summary, the principle phenotype of MBC was luminal A, ductal, grade 2.

15 ion of several intrinsic molecular subtypes: luminal A, luminal B, human epidermal growth factor rece

16 of the intrinsic subtypes of breast cancer (luminal A, luminal B, human epidermal growth factor rece

17 (IBTR) as a first event within 10 years for luminal A-like tumors (19% v 9%; P = .001), luminal B-li

18 The effect of RT in the presumed low-risk luminal A-like tumors was excellent.

19 nsidered, GRPR was overexpressed in 86.2% of luminal A-like tumors, 70.5% of luminal B-like human epi

20 An increase in survival for the luminal-A and basal BC molecular subtypes was observed a

21 Using confocal microscopy and measuring luminal accumulation of fluorescent substrates, we asses

22 study shows that medullary A-ICs respond to luminal adenosine through ADORA2A and ADORA2B receptors

23 NSAID inhibition of COX enzymes, along with luminal aggressors, results in erosions and ulcers, with

24 popular tools using human-in-mouse xenograft luminal and basal breast tumor samples that are known to

25 Bcl11b and located at the interface between luminal and basal cells.

26 E17.5 coincident with the segregation of the luminal and basal compartments.

27 t subtypes of prostate cancer may arise from luminal and basal epithelial cell types subjected to the

28 o identify prostate cancer subtypes based on luminal and basal lineage and to determine associations

29 vo histomorphologic patterns consistent with luminal and basal subtypes, including papillary architec

30 component, which mediates degradation of ER luminal and membrane substrates.

31 orting the degradation of well characterized luminal and membrane substrates.

32 e networks were constructed for the adjacent luminal and mucosal compartments.

33 We review the features of the luminal and mucosal microenvironment of Barrett's esopha

34 In the present study, luminal and mucosal samples taken along the longitudinal

35 epidermal growth factor receptor 2-positive (luminal and nonluminal) tumors (15% v 19%; P = .6); howe

36 rocess, as suggested by results obtained for luminal and nuclear membrane-associated EGFP-tagged prot

37 D pathway signaling is strongly activated in luminal and suprabasal cells of several epithelia, but s

38 the Golgi complex by virtue of the proteins' luminal and transmembrane domains.

39 Luminal- and basal-like prostate cancers demonstrate div

40 ively collected prostate cancer samples into luminal- and basal-like subtypes.

41 ity against MDA-MB-453 cells, a model of the luminal androgen receptor (LAR) subtype of TNBC.

42 pes of the human fallopian tube as well as a luminal architecture that closely reflects the organizat

43 mal macrophage switching in both mucosal and luminal areas of COPD patients, that strongly associated

44 ive, 538 [34.3%]; prospective, 737 [33.3%]), luminal B (retrospective, 447 [28.5%]; prospective, 723

45 tients based on clinicopathologic variables (luminal B 10-year metastasis: treated, 33% vs untreated,

46 te to estrogen receptor (ER)(+) luminal A or luminal B and ER(-) basal-like cancers and to different

47 ion, luminal/HER2-negative tumors acquired a luminal B or HER2-E profile during metastatic progressio

48 In the retrospective cohort, luminal B prostate cancers exhibited the poorest clinica

49 ogen receptor expression and signaling, only luminal B prostate cancers were significantly associated

50 o the combination treatment of patients with luminal B tumors irrespective of progesterone receptor s

51 vergent clinical behavior, and patients with luminal B tumors respond better to postoperative ADT tha

52 % in HER2-enriched (HER2-E) tumors, 30.0% in luminal B tumors, and 55.3% in luminal A tumors.

53 lecular subtype (P = .03); for patients with luminal B tumors, the combination:anastrozole geometric

54 0.2% of cases, luminal A tumors converted to luminal B tumors, whereas in 14.3% of cases luminal A an

55 postoperative ADT than do patients with non-luminal B tumors.

56 t strategies should be considered for older, luminal B, and HER2 driven BC patients.

57 rinsic subtypes of breast cancer (luminal A, luminal B, human epidermal growth factor receptor 2 [cur

58 ral intrinsic molecular subtypes: luminal A, luminal B, human epidermal growth factor receptor 2 enri

59 d the magnitude of changes of proliferation, luminal B, or HER2-E signatures in metastatic versus pri

60 receptor 2 (HER2)-negative tumors, 82.8% of luminal B-like HER2-positive tumors, 21.3% of HER2-enric

61 in 86.2% of luminal A-like tumors, 70.5% of luminal B-like human epidermal growth factor receptor 2

62 luminal A-like tumors (19% v 9%; P = .001), luminal B-like tumors (24% v 8%; P < .001), and triple-n

63 Despite increased luminal BA, colonocytes from WD-fed mice exhibited decre

64 ath of labelled surface molecules from live, luminal bacteria into specific intestinal immune cells i

65 transepithelial cellular processes to sample luminal bacteria or, very early after infection, migrate

66 Modifications of the luminal bacterial metabolite concentrations may, in addi

67 d1 in complex with its endoplasmic reticulum luminal binding partner, Hrd3.

68 induced PPAR-gamma signaling also limits the luminal bioavailability of oxygen by driving the energy

69 across Golgi membranes is essential for the luminal biosynthesis of glycan structures.

70 Foxa1 expression is linked with luminal breast cancer (LBC) with good prognosis, whereas

71 t on tumor onset in an ErbB2-driven model of luminal breast cancer [murine mammary tumor virus promot

72 We develop experimental models of metastatic luminal breast cancer and demonstrate that HT can promot

73 l breast cancer cell line MDA-MB-231 and the luminal breast cancer cell line MCF7: a) a 3D collagen e

74 nergized with DAC to reduce the viability of luminal breast cancer cells in in vitro assays.

75 l concentrations, suppresses invasiveness of luminal breast cancer cells through the estrogen recepto

76 Distal metastasis of luminal breast cancer is frequent and incurable, yet the

77 lase KDM5B is amplified and overexpressed in luminal breast cancer, suggesting it might constitute a

78 amental mechanism that enables metastasis of luminal breast cancer.

79 rmonal therapy resistance (HTR) in models of luminal breast cancer.

80 ogen receptor (ER) drives the growth of most luminal breast cancers and is the primary target of endo

81 R-A may help predict metastatic potential of luminal breast tumors.

82 elial water absorption, nutrient inflow, and luminal buffering capacity, and generates testable predi

83 ase from nj-SR is activated by cytosolic and luminal Ca(2+) (tandem RyR activation) via a novel 'fire

84 ally to cytosolic Ca(2+) , ATP, caffeine and luminal Ca(2+) .

85 solic Ca(2+) , ATP, adenine, caffeine and to luminal Ca(2+) .

86 A model suggested that luminal Ca(2+) activates RyR1 by accessing a recently id

87 osolic Ca(2+), it plays an important role in luminal Ca(2+) activation and SOICR.

88 ildtype RyR1 was closed and not activated by luminal Ca(2+) at low cytosolic Ca(2+) levels.

89 We suggest that doxOL and low luminal Ca(2+) both disrupt the CSQ2 polymer, and that t

90 system, an adaptive mechanism that senses ER luminal Ca(2+) concentrations through the STIM proteins

91 render the channel insensitive to changes of luminal Ca(2+) that occur through the cardiac cycle.

92 tores, which is consistent with increased SR luminal Ca(2+) These findings define critical roles for

93 ndem activation of the RyRs by cytosolic and luminal Ca(2+) through a 'fire-diffuse-uptake-fire' (or

94 abolished the increase in RyR2 activity when luminal Ca(2+) was increased from 0.1 to 1.5 mM.

95 at 2 mum cytosolic or sarcoplasmic reticulum luminal Ca(2+), and Ca(2+)- and voltage-dependent regula

96 , and the conserved acidic residues form the luminal Ca(2+)-blocking site that confers luminal pH and

97 he increase in RyR2 activity with increasing luminal [Ca(2+)] away from the physiologic [Ca(2+)] rang

98 on of doxOL on RyR2's response to changes in luminal [Ca(2+)] seen during diastole.

99 Q2, and the lost RyR2 response to changes in luminal [Ca(2+)], was duplicated by exposing native RyR2

100 2 channels to subphysiologic (</=1.0 microM) luminal [Ca(2+)].

101 At low luminal calcium concentrations, ouf8 had little detectab

102 No intra-luminal cancers were detected.

103 Disrupting luminal cell AR signaling in mouse models promotes cytok

104 tor that regulates genes involved in mammary luminal cell differentiation and tumor suppression.

105 In summary, Foxc1 regulates sweat duct luminal cell differentiation, and mutant mice mimic mili

106 ster regulator of mammary alveologenesis and luminal cell differentiation, is markedly reduced in mam

107 Establishment of the mammary luminal cell lineage is controlled primarily by hormones

108 eration, without affecting androgen-mediated luminal cell survival or regeneration.

109 ogenitors, which express both basal cell and luminal cell-enriched genes.

110 of PKCzeta directs the resistant CSCs to the luminal cell-like state and sensitization to tamoxifen,

111 In contrast, AR deletion in luminal cells alters cell morphology and induces transie

112 ) binding to the 11-kb region in both normal luminal cells and CARNs and discovered new androgen resp

113 tates acquisition of MaSC-like properties by luminal cells and predisposes them to development of mam

114 Mutant luminal cells did not exhibit their distinctive transcri

115 ort that induced p53 loss in Krt8(+) mammary luminal cells leads to their clonal expansion without di

116 Nkx3.1 is ubiquitously expressed in luminal cells of hormonally intact prostate but, upon an

117 ncy contributes to breast tumorigenesis from luminal cells remains elusive.

118 anching, producing stunted ducts filled with luminal cells showing altered ovarian hormone receptor e

119 transduced primary human prostate basal and luminal cells with lentiviruses expressing c-Myc and act

120 t claudin-low breast cancer can develop from luminal cells, possibly via a basal-like intermediate st

121 be bipotent and can generate either basal or luminal cells, whereas the luminal epithelium has not be

122 terminal differentiation markers in the duct luminal cells, which most likely contribute to keratotic

123 lower levels, in oestrogen receptor-positive luminal cells.

124 c basal cells into transformation-preferable luminal cells.

125 d group of proteins in addition to basal and luminal clusters, and pathway analysis of the phosphopro

126 Here, we report that the ER luminal co-chaperone ERdj4/DNAJB9 is a selective IRE1 re

127 Despite the increased luminal colonization by Salmonella, CD73(f/f)Villin(Cre)

128 that the epithelial cells-especially in the luminal compartment-should rather be conceptualised as b

129 n override AR-loss effects in both basal and luminal compartments to initiate tumours.

130 xpenditure and macronutrient preference, the luminal composition of the gut (i.e., the microbiota and

131 sine triphosphatase (V-ATPase) increased the luminal concentrations of most metabolites but had no ef

132 bolite concentrations in the large intestine luminal content, notably after changes in the dietary co

133 helium is a functional barrier that secludes luminal content, senses changes in the gut microenvironm

134 cell migration to seal the damaged area from luminal contents, whereas chronic inflammation leads to

135 These findings link luminal conversion of amino acids to biogenic amines by

136 ration through the lymphatic endothelium and luminal crawling.

137 elial cells, in which CLIC4 is important for luminal delivery, microvillus morphogenesis, and endolys

138 s also associated with further promoting the luminal deposition of platelet-derived regulated on acti

139 ), signal-to-noise ratio, and consistency of luminal diameter measurements were quantified.

140 sed by (1) vessel score (>/=50% reduction in luminal diameter), and (2) Extent score (Reardon scoring

141 to GATA3, FoxM1b also represses the mammary luminal differentiation marker FoxA1 by promoter-methyla

142 e, but is cell-autonomously required for the luminal differentiation of rare basal stem cells.

143 s based primarily on maximal coronary artery luminal dimensions, normalized as Z scores, and is calib

144 re we report a crystal structure of a LIMP-2 luminal domain dimer with bound cholesterol and phosphat

145 Retrotranslocation of the luminal domain of a membrane-spanning substrate is trigg

146 d its interaction with insect cell expressed luminal domain of S. cerevisiae Gpi16.

147 Here, we expressed and purified the luminal domain of Saccharomyces cerevisiae (S. cerevisia

148 An antibody targeting the luminal domain of syt1, on the other hand, showed that a

149 etion of the unfolded protein stress-sensing luminal domain of the UPR transducers PERK and IRE1alpha

150 and trypanosome GPIT, our data show that the luminal domains of S. cerevisiae Gpi8 and S. cerevisiae

151 insights to study the oligomerization of the luminal domains of two nuclear membrane proteins, nespri

152 of the epithelial cycle, from the BM to the luminal edge of the tubule, possibly being used to modul

153 ar events of spermiation that occur near the luminal edge of tubule lumen at the apical ES and the ba

154 ls and a significantly increased presence of luminal endothelial cell-cell junctions, a transient con

155 Toll-like receptor 2 agonism activated luminal endothelial cells, and deficiency of this innate

156 s observational studies have documented late luminal enlargement and expansive remodeling following i

157 th a preference for divalent cations, at the luminal entrance.

158 tribution of major changes in the colonocyte luminal environment in pathological processes, like muco

159 e to face, up to some extent, changes in its luminal environment, notably by developing a metabolic a

160 ical in protecting the host from the hostile luminal environment.

161 gland epithelium consists of differentiated luminal epithelial and basal myoepithelial cells, as wel

162 is the master regulator that drives mammary luminal epithelial cell differentiation and maintains ma

163 nd ER(-) basal-like cancers and to different luminal epithelial cell populations in the adult mammary

164 highlight SPOP as an important regulator of luminal epithelial cell proliferation and c-MYC expressi

165 benign human prostate but is upregulated in luminal epithelial cells in foci of prostatic malignancy

166 shift from androgen receptor (AR)-dependent luminal epithelial cells to AR-independent basal-like ce

167 control elements that are active in prostate luminal epithelial cells would induce the development of

168 R-loops accumulate preferentially in breast luminal epithelial cells, not in basal epithelial or str

169 (Levitra) mobilized FoxO3a to the nucleus of luminal epithelial cells, which corresponded to increase

170 However, the AR is a key factor in luminal epithelium differentiation and was shown to have

171 In Fst-cKO mice, the uterine luminal epithelium does not respond properly to estrogen

172 e either basal or luminal cells, whereas the luminal epithelium has not been demonstrated to contribu

173 luminal syringeal tissues, especially in the luminal epithelium of the trachea and pessulus.

174 le transcription factor, NFATc1 in prostatic luminal epithelium to PCa can affect expression of diver

175 inal bleeding and delayed restoration of the luminal epithelium.

176 , although p53 does not directly control the luminal fate, its loss facilitates acquisition of MaSC-l

177 In mouse cells, depletion of ER luminal FKBP10 was almost as potent as FK506 in attenuat

178 lar composition of the mouse intestine, with luminal flow to control perturbations (e.g., microbes, d

179 g peristalsis-like motions while maintaining luminal flow, lack of epithelial deformation was shown t

180 estine allows for appropriate adjustments in luminal fluidity while reclaiming water used in digestin

181 rs (nuclear, cytoplasmic, cellular, stromal, luminal fractions) were determined.

182 ing of the luminal gate, and thereclosing of luminal gate induces a shift in the cytoplasmic domains

183 that subsequently drives the opening of the luminal gate, and thereclosing of luminal gate induces a

184 al, vascular side, while SGLT1 is exposed to luminal glucose at the apical side of the cell, suggesti

185 s SGLT1 in the brush-border membrane at high luminal glucose concentration.

186 nd regulation of V-type ATPase, compromising luminal H(+) secretion and possibly lysosomal acidificat

187 Intracellular bicarbonate generated by luminal H(+) secretion is removed by the basolateral ani

188 Lactobacillus reuteri in the gut resulted in luminal hdc gene expression and histamine production in

189 ly maintained during metastatic progression, luminal/HER2-negative tumors acquired a luminal B or HER

190 The steady-state luminal heterogeneity index was low, and signal-to-noise

191 Expression of a luminal HRP-tagged syt1 construct and subsequent H2 O2 a

192 epressor that promotes a complex between the luminal Hsp70 BiP and the luminal stress-sensing domain

193 ) chains are produced in both basal-like and luminal human breast tumours, and its expression levels

194 l expansion without directly affecting their luminal identity.

195 development of mammary tumours with loss of luminal identity.

196 egulatory T cells and a higher production of luminal IgA.

197 d canopy atop the channel, providing several luminal ion passages to the pore and creating a negative

198 prevalence of atherosclerotic plaques of any luminal irregularity (44.3% versus 22.2%; P=0.009) compa

199 ded vacuole signal peptide transports the ER-luminal LDs to vacuoles.

200 avage of recombinant proteins exposed on the luminal leaflet of transport vesicles.

201 , such as NKX3.1 and KRT18, were enriched in luminal-like cancers, and the basal lineage CD49f signat

202 Although both luminal-like subtypes were associated with increased and

203 -positive breast cancers as some may be more luminal-like than HER2 driven.

204 s, thus minimizing their contribution to the luminal lineage and the mature duct.

205 Known luminal lineage markers, such as NKX3.1 and KRT18, were

206 A luminal linker domain forms a fenestrated canopy atop th

207 -regulatory factors such as dietary iron and luminal lipocalin 2 should be taken into consideration f

208 domain of sortilin interacts with the first luminal loop of Glut4, and the cytoplasmic tail of sorti

209 However, luminal macrophages showed a dominant M2 phenotype in bo

210 minority of triple-negative tumours express luminal markers, such as androgen receptors, and have a

211 Interobserver luminal measurements were reliable (intraclass correlati

212 s essential for CaOx crystal adhesion to the luminal membrane of renal tubules as a fundamental initi

213 erved that beta1-integrins accumulate on the luminal membrane of upper-airway epithelial cells from m

214 investigated the nature of IEL responses to luminal microbes.

215 l tissues and specialized for the capture of luminal microparticles and their delivery to underlying

216 Importantly, tumors with a luminal molecular subtype have a significantly higher ra

217 The severity of luminal narrowing in the diseased segments was unchanged

218 h marginal inflammation who exhibited airway luminal narrowing without wall thickening.

219 In luminal nonmetastatic MCF-7 breast cancer cells, HuR sil

220 with EoE had evidence for an acute response (luminal obstruction and mucosal blanching); 2 other pati

221 laques with similar degree of calcification, luminal obstruction, localization, and imaging parameter

222 damage through rapid intimal hyperplasia and luminal occlusion.

223 nal progeny contribute exclusively to either luminal or basal lineages and are distributed sporadical

224 g of the histomorphology of various internal luminal organs and studying the pathogenesis of relevant

225 tion, it remains challenging to access small luminal organs or pass through narrow luminal sections w

226 Most breast cancers may have a luminal origin.

227 he luminal Ca(2+)-blocking site that confers luminal pH and Ca(2+) modulation on channel conductance.

228 Luminal pH and phosphoinositide content are fundamental

229 tdIns(3)P) persists on tPCs as long as their luminal pH remains neutral.

230 nching which, in higher plants, requires the luminal pH sensor PsbS and other yet unidentified compon

231 The sub-luminal phase velocity of electromagnetic waves in free

232 The requirement of sub-luminal phase-velocity in laser-driven particle accelera

233 are part of the Hippo pathway, promotes the luminal phenotype and increases the number of bipotent a

234 e platforms that trap beta1-integrins on the luminal pole of bronchial epithelial cells.

235 , our data support the existence of a common luminal progenitor cell giving rise to intermediate, res

236 -kappaB pathways are aberrantly activated in luminal progenitor cells resident in preneoplastic BRCA1

237 ounts for the susceptibility of BRCA1(mut/+) luminal progenitor cells to oncogenesis and tissue speci

238 This luminal progenitor compartment undergoes transcriptional

239 ds contain an abnormal population of mammary luminal progenitors that can form 3D colonies in a hormo

240 antage of a region-specific heterogeneity in luminal progenitors to interrogate the differentiation r

241 ype and increases the number of bipotent and luminal progenitors, the proposed cells-of-origin of mos

242 highly clonogenic ALDH(+)/CD49f(+)/EpCAM(+) luminal progenitors, which express both basal cell and l

243 st tumours are basal-like yet originate from luminal progenitors.

244 te, although further study using a different luminal promoter is needed to fully support this conclus

245 o-phase front conversion to overcome the sub-luminal propagation limit.

246 lling source approach that overcomes the sub-luminal propagation limits.

247 In vivo, CCPG1 protects against ER luminal protein aggregation and consequent unfolded prot

248 accomplish retrotranslocation of a misfolded luminal protein domain across a lipid bilayer, we have r

249 t this may be physiologically relevant in ER luminal proteostasis.

250 ooms, which may be driven by fluctuations in luminal redox.

251 d migration-related genes and diminished for luminal-related genes.

252 -PBA triggers the secretion of a KDEL-tagged luminal resident, implying that a compromised retention

253 ront elevates local [Ca(2+) ]SR , leading to luminal RyR sensitization and lowering of the activation

254 tes Ca(2+) inside the SR locally, leading to luminal RyR sensitization and lowering of the cytosolic

255 es loop 1 to dissociate from loop 7, another luminal Scap loop.

256 Although luminal SCFAs evoke electrogenic anion secretion and smo

257 small luminal organs or pass through narrow luminal sections without potentially causing trauma to t

258 tric oxide by the endothelium in response to luminal shear stress, which increases secondary to arter

259 Here we report that the luminal side of liver blood vessels contains fibronectin

260 ic vessels and subsequent crawling along the luminal side of the lymphatic endothelium.

261 ponding active site for SOAT2 located on the luminal side.

262 one or two Hrd3 molecules associated at its luminal side.

263 dependent binding kinetics and the pH at the luminal side.

264 ratio between the mean standard deviation of luminal signal intensity and the mean luminal signal int

265 ion of luminal signal intensity and the mean luminal signal intensity), signal-to-noise ratio, and co

266 s how diarrhea can result from a decrease in luminal solute absorption, an increase in secretion, or

267 the distal colon epithelium, with prominent luminal staining.

268 ed by castration-resistant Nkx3.1-expressing luminal stem cells (CARNs).

269 Blimp1(+) luminal stem cells give rise to Blimp1(-) progeny that a

270 en deprivation, exclusively labels a type of luminal stem cells named castration-resistant Nkx3.1-exp

271 imaging revealed these long-lived unipotent luminal stem cells survive consecutive involutions and r

272 sion marks a rare subpopulation of unipotent luminal stem cells that initially appear in the embryoni

273 ed a CAC >/=300 Agatston units (11.3%) and a luminal stenosis >/=50% (7.5%).

274 ased risk of CAC >70th percentile for age or luminal stenosis >/=50% in male athletes (odds ratio, 1.

275 ocardial infarction, including 3(42%) with a luminal stenosis >/=50% in the corresponding artery.

276 aired vasoregulatory ability and significant luminal stenosis.

277 omplex between the luminal Hsp70 BiP and the luminal stress-sensing domain of IRE1alpha (IRE1(LD)).

278 identify and quantify dynamic changes to the luminal structure of murine uterus in preparation for im

279 organoid to self-organize into a convoluted luminal structure, permitted matured differentiation to

280 hat differentiate while migrating toward the luminal surface and eventually desquamate.

281 d robust neointimal hyperplasia on the patch luminal surface characterized by Eph-B4-positive endothe

282 , after 5 days in culture, ECs seeded on the luminal surface of 8g7-coated decellularized arteries sh

283 glycocalyx forms a continuous coat over the luminal surface of all vessels, and regulates multiple v

284 NS where they first roll and crawl along the luminal surface of leptomeningeal vessels without showin

285 on from the basal (abluminal) to the apical (luminal) surface across LEC, whereas for blood endotheli

286 The membrane "immunocloaks" the luminal surfaces within the renal vasculature by coverin

287 intriguing puzzle: some variants may augment luminal surveillance to boost mucosal immunity, while ot

288 free nerve endings were also present in the luminal syringeal tissues, especially in the luminal epi

289 to the increased intestinal permeability of luminal toxins.

290 ptor and HER2 status, and further stratified luminal tumors based on proliferation.

291 on following RB inactivation in an RB-intact luminal-type breast cancer cell line MCF-7 promoted a po

292 In contrast, luminal-type breast cancer cells are cystine-independent

293 The gene expression profile of luminal-type breast cancer patients with low RB expressi

294 1 was higher in normal breast, low-grade and luminal-type cancer in comparison with breast carcinoma,

295 membrane to mediate cargo sorting and intra-luminal vesicle formation.

296 EM increases monotonically with decreases in luminal volume.

297 Mechanistically, the luminal Vps10p domain of sortilin interacts with the fir

298 , T2short, T2long, geometric mean T2 (gmT2), luminal water fraction (LWF), Ashort, and Along, were ge

299 pilot study demonstrated the feasibility of luminal water imaging in the detection and grading of PC

300 Purpose To assess the feasibility of luminal water imaging, a quantitative T2-based magnetic