ライフサイエンスコーパス: lung biopsy

1 id, and characteristic histologic changes on lung biopsy.

2 ist are sufficient to obviate the need for a lung biopsy.

3 titial pneumonia (UIP) confirmed by surgical lung biopsy.

4 ovided an overall diagnosis, before surgical lung biopsy.

5 pneumonia had the vaccine strain of VZV in a lung biopsy.

6 atients had idiopathic PAP confirmed by open lung biopsy.

7 ls found in bronchoalveolar lavage fluid and lung biopsy.

8 , bronchoalveolar lavage, and transbronchial lung biopsy.

9 agnoses inconsistently confirmed by adequate lung biopsy.

10 ts, often obviating the need to perform open-lung biopsy.

11 eries of patients diagnosed by bronchoscopic lung biopsy.

12 for the increased risk associated with open lung biopsy.

13 he immunohistochemical features on liver and lung biopsy.

14 nchoalveolar lavage, genetic testing, and/or lung biopsy.

15 are being evaluated to decrease the need for lung biopsy.

16 cal symptoms and, if available, CT scans and lung biopsies.

17 mograms, blood chemistries, radiographs, and lung biopsies.

18 t based on the results of the transbronchial lung biopsies.

19 s for interstitial lung disease and surgical lung biopsies.

20 immunohistochemical staining of IPF surgical lung biopsies.

21 ent a biopsy of each lung, for a total of 20 lung biopsies.

22 e-related mortality was four-fold higher for lung biopsy (0.0078) compared with BAL (0.0018).

23 However, complications were more common with lung biopsy (0.15 v 0.08; P = .006), and procedure-relat

24 nosis was more common with BAL compared with lung biopsy (0.49 v 0.34; P < .001).

25 d (2), liver biopsy (2), colonic biopsy (1), lung biopsy (1), and stool (1).

26 tients were diagnosed to have amyloidosis by lung biopsy (15 surgical, 2 transthoracic needle, and 1

27 All cases underwent lung biopsies: 58 were BLC, and 59 were surgical lung bi

28 total of 49 soldiers underwent thoracoscopic lung biopsy after noninvasive evaluation did not provide

29 Of the 49 soldiers who underwent lung biopsy, all biopsy samples were abnormal, with 38 s

30 T and CXCR3 expression in human IPF surgical lung biopsies and assessed whether CXCR3 and its ligand

31 Messenger RNA in transbronchial lung biopsies and bronchoalveolar lavage cell pellet and

32 samples, miR-17~92 expression was reduced in lung biopsies and lung fibroblasts from patients with IP

33 SHH) pathway members in normal and IPF human lung biopsies and primary fibroblasts.

34 Thoracoscopic lung biopsy and bronchoalveolar lavage were not conducte

35 The mean cost per patient for lung biopsy and pneumothorax management was as follows:

36 pathologic evidence of fibrosis at surgical lung biopsy and to compare a usual interstitial pneumoni

37 obtained from two patients 1 to 2 days after lung biopsy and which were sterile by culture were posit

38 cells in vitro, colocalizes to mast cells in lung biopsies, and is elevated in asthmatic airways.

39 minantly solid pattern of LAM lesions in the lung biopsy, and greater rate of decline in expiratory f

40 ng studies, bronchoalveolar lavage, surgical lung biopsy, and histopathologic assessment, improved ou

41 on complications after transthoracic needle lung biopsy are limited to case series from selected ins

42 ngs alone and for considering transbronchial lung biopsy as a diagnostic tool.

43 olution CT as part of screening and surgical lung biopsy as part of standard clinical care.

44 iNOS was measured in central and peripheral lung biopsies, as well as BAL cells.

45 try, blood analyses, chest radiographs, open lung biopsies, as well as tissue drug concentrations and

46 cant reduction (P < .016) in intraprocedural lung biopsy-associated pneumothorax was found when the e

47 A surgical lung biopsy at the time of grafting revealed characteris

48 Transbronchial lung biopsy can be performed with an acceptable risk and

49 ressed at significantly higher levels in UIP lung biopsies compared with biopsies from patients with

50 nts (22%) in the bellows group who underwent lung biopsy compared with 16 of 50 (32%) patients in the

51 ybridization (FISH) studies performed on the lung biopsy confirmed a normal XY genotype.

52 Histologic analysis of transbronchial lung biopsies demonstrated a few eosinophils within the

53 everity of fibrosis and cellularity found on lung biopsy determine the prognosis and response to ther

54 s well as new insights into the role of open lung biopsy, diaphragmatic dysfunction, and a potential

55 Surgical lung biopsies disclosed nonspecific interstitial pneumon

56 To test this hypothesis, we obtained open lung biopsies either from normal patients undergoing tho

57 ematologic malignancy, who underwent 67 open lung biopsies for diagnosis of an unknown pulmonary proc

58 n-hospital mortality after elective surgical lung biopsy for interstitial lung disease is just under

59 pients of HSCT, and if they underwent BAL or lung biopsy for the evaluation of pulmonary lesions.

60 Pathologists reviewed surgical lung biopsies from 108 patients with usual interstitial

61 Lung biopsies from 11 patients with pulmonary eosinophil

62 We profiled lung biopsies from 15 patients with IPF, 12 with HP, and

63 We took 125 surgical lung biopsies from 86 patients.

64 Open lung biopsies from eight patients with CFA, nine patient

65 We obtained open lung biopsies from patients undergoing thoracic surgery

66 Phosphorylated STAT-3 was elevated in lung biopsies from patients with idiopathic pulmonary fi

67 We used tissue sections of surgical lung biopsies from patients with IPF to localize express

68 tasis on HRCT and had not undergone surgical lung biopsy had disease that progressed in a similar way

69 problems such as empyema, pneumothorax, and lung biopsy has significantly altered our treatment algo

70 The yield and impact of open lung biopsies in patients with hematologic malignancies

71 ia in bronchoalveolar lavage fluid (BALF) or lung biopsies in the absence of infection, atopy, or ast

72 issue available for histopathology (surgical lung biopsy in 28 patients and explanted lung in two pat

73 cases (61.8%); clinical history and surgical lung biopsy in 56 cases (18.1%); and clinical history an

74 puted tomography, thus avoiding the need for lung biopsy in most patients.

75 We conclude that open lung biopsy in patients with hematologic malignancy has

76 to permit diagnosis of IPF without surgical lung biopsy in select cases when CT shows a probable UIP

77 Bronchoalveolar fluid analysis and lung biopsy in selected case reports revealed several di

78 st computed tomography, genetic testing, and lung biopsy in the diagnostic evaluation of children wit

79 ion rate of bronchoalveolar lavage (BAL) and lung biopsy in the evaluation of pulmonary lesions in pa

80 Lung biopsy is most helpful when clinical and radiologic

81 It is not known if a surgical lung biopsy is necessary in all patients for the diagnos

82 Surgical lung biopsy is often required for a confident multidisci

83 Lung biopsy light microscopy demonstrated a marked reduc

84 tissue samples from all the cases for which lung biopsy material was available (15 of 20 cases known

85 Further diagnostic measures, including lung biopsies, may be limited to rare, complicated cases

86 Lung biopsy more commonly led to a noninfectious diagnos

87 7.3%) by bronchoalveolar lavage (n=68), open lung biopsy (n=3), or autopsy (n=14).

88 s: previous chest operations other than open lung biopsy (n=6 patients having 1-4 previous operations

89 nd their corresponding receptors in surgical lung biopsies obtained at the time of disease diagnosis

90 An open-lung biopsy obtained from the second patient allowed a q

91 Lung function of 143 patients and lung biopsies of 74 of these patients were reviewed for

92 alysis of 104 patients with IPF who had open lung biopsy (OLB) at Mayo Medical Center from 1976 to 19

93 done in 94.7% of patients and surgical open lung biopsy (OLB) in 20.3%.

94 n computed tomography (HRCT, n = 25) or open-lung biopsy (OLB, n = 1) patterns typical for idiopathic

95 oscopy with transbronchial and endobronchial lung biopsies or endosonography (esophageal or endobronc

96 histopathologic presence of the organism at lung biopsy or (b) a positive culture of a respiratory s

97 e such patients who had undergone diagnostic lung biopsy or autopsy were examined.

98 y specimens and lung tissue obtained by open-lung biopsy or post mortem examination occurred in 11 (8

99 ties in a subset of patients undergoing open lung biopsy or transplantation or whose lung tissue was

100 ormalities underwent bronchoalveolar lavage, lung biopsy, or both.

101 RATIONALE: In the absence of a surgical lung biopsy, patients diagnosed with idiopathic pulmonar

102 estimated there to be around 12,000 surgical lung biopsies performed annually for interstitial lung d

103 requent complication of transthoracic needle lung biopsy, pneumothorax is common and often necessitat

104 The extent of fibroblastic foci present on lung biopsy predicts survival in IPF.

105 The use of specimens acquired from lung biopsy procedures to identify biomarkers of clinica

106 Eighty-three transbronchial lung biopsy procedures were performed in this patient co

107 is could be attributed to the transbronchial lung biopsy procedures.

108 during percutaneous CT-guided transthoracic lung biopsy reduces the rate of overall pneumothorax and

109 ted tomographic (CT) scans of the chest, and lung biopsy reports were submitted by referring centers

110 76 years) with chronic HP had their surgical lung biopsy results reviewed by two pathologists for the

111 hoalveolar lavage were unrevealing, and open lung biopsy revealed active small vessel vasculitis.

112 Open lung biopsy revealed extrinsic allergic alveolitis (hype

113 Trans-bronchial lung biopsy revealed intraluminal organization and fibri

114 Lung biopsy revealed perivascular and interstitial eosin

115 An open lung biopsy revealed pulmonary capillaritis.

116 An unknown virus was isolated from a lung biopsy sample and multiple other samples from a pat

117 existing and subsequently obtained surgical lung biopsy samples and from lung explants.

118 ere obtained from 49 patients and 55 in vivo lung biopsy samples from computed tomographic [CT]-guide

119 We collected surgical lung biopsy samples from patients with various interstit

120 Open lung biopsy samples were scored for cellular infiltratio

121 equire histological confirmation of surgical lung biopsy samples when high-resolution CT images are n

122 versus normal areas of lung in IPF surgical lung biopsy samples.

123 other interstitial lung diseases in surgical lung biopsy samples.

124 IPF had both high-resolution CT and surgical lung biopsy samples.

125 onia pattern on high resolution CT, surgical lung biopsy sampling might not be necessary to reach a d

126 he primary outcome was comparison of average lung biopsy scores at 6 months.

127 osis was idiopathic pulmonary fibrosis; open lung biopsy shortly before his death confirmed asbestosi

128 ary capillaritis may have negative serology, lung biopsy should be strongly considered in any child w

129 dditional investigations, including surgical lung biopsy, should be considered in patients with eithe

130 Histopathology from the lung biopsy showed structures consistent with B. dermati

131 over, heparanase content was higher in human lung biopsies showing diffuse alveolar damage than in no

132 and six of these patients also had surgical lung biopsy showing a pattern consistent with chronic hy

133 A video-assisted thoracoscopic lung biopsy shows findings of usual interstitial pneumon

134 Findings of surgical lung biopsy (SLB) are important in categorizing patients

135 biopsies: 58 were BLC, and 59 were surgical lung biopsy (SLB).

136 pulmonary fibroblasts grown out of surgical lung biopsies (SLBs) from IIP patients based on their ex

137 Staining of UIP lung biopsy specimens demonstrated that phosphorylated S

138 Lung biopsy specimens from asthmatic and nonasthmatic pa

139 Staining of lung biopsy specimens from patients with acute lung inju

140 Paraffin-embedded lung biopsy specimens from patients with RA (n = 15) and

141 Lung biopsy specimens from patients with RA-associated i

142 Open-lung biopsy specimens from patients with RA-associated I

143 Recut sections were obtained from lung biopsy specimens from seven male recipients of tran

144 emodeling-associated genes in transbronchial lung biopsy specimens from two cohorts with 18 patients

145 tion were examined in fibroblasts grown from lung biopsy specimens obtained from 16 scleroderma patie

146 T-cell lines derived from lung biopsy specimens of asthmatic patients were charact

147 Gastrointestinal and lung biopsy specimens of subjects with inflammatory dise

148 With open lung biopsy specimens the following assays yielded the i

149 At each time point, lung biopsy specimens were scored for rejection.

150 Bronchoalveolar lavage (BAL) fluid and lung biopsy specimens were stained with hematoxylin and

151 ngulfing degenerating lamellar bodies and/or lung biopsy specimens with alveolar spaces filled with h

152 nd 24 formalin-fixed, paraffin-embedded open lung biopsy specimens.

153 eous analysis of the 16 DNA adducts in human lung biopsy specimens.

154 otein receptor type 1A (BMPR1A) and BMPR2 in lung-biopsy specimens from patients with pulmonary hyper

155 th noncaseating necrosis from transbronchial lung biopsy (TBLB) specimen, increasing of lymphocyte an

156 positive plus had histopathology on surgical lung biopsy that was consistent with hypersensitivity pn

157 ge fluid; and three had findings on surgical lung biopsy that were consistent with subacute hypersens

158 s had histopathological features on surgical lung biopsy that were consistent with this diagnosis.

159 Bronchoscopy with transbronchial lung biopsies, the current diagnostic standard, has mode

160 T characteristics but are unfit for surgical lung biopsy, therefore preventing a confident diagnosis.

161 Immunohistochemistry of lung biopsy tissue in five HIV-negative patients showed

162 In gastrointestinal and lung biopsy tissues of patients with CVID, numerous IFN-

163 oalveolar lavage and repeated transbronchial lung biopsies to determine progression to chronic beryll

164 to the contrary, we have found bronchoscopic lung biopsy to be a safe and effective diagnostic techni

165 n immunocompetent patient documented at open lung biopsy to be due to Mycobacterium haemophilum.

166 hout a typical NEHI presentation, and thus a lung biopsy to differentiate the diseases is indicated.

167 dentify patients who should undergo surgical lung biopsy to secure a definitive histological diagnosi

168 Cellular infiltration score of the open lung biopsies was higher in responders (7.6+/-0.6) than

169 repeat spoligotyping of 85 paraffin-embedded lung biopsies was used to investigated the occurrence ar

170 duration of symptoms 4.6 yr, and time since lung biopsy was 3.2 yr.

171 clinician, radiologist, and pathologist (if lung biopsy was completed) independently evaluated each

172 Lung biopsy was most important for diagnosis in those pa

173 08 and December 2009, percutaneous CT-guided lung biopsy was performed in 201 patients.

174 In the three patients in whom open lung biopsy was performed, there was bronchiolocentric i

175 Serial lung biopsies were examined by light microscopy and immu

176 Concurrent proximal airway and distal lung biopsies were obtained by bronchoscopy from subject

177 amples from computed tomographic [CT]-guided lung biopsies were obtained from 25 patients) and quanti

178 Before, during, and after CPB, peripheral lung biopsies were performed to determine tissue NO, nit

179 160 coaxial computed tomography (CT)-guided lung biopsies were performed.

180 y (CT) guided and 24 fluoroscopically guided lung biopsies were performed.

181 The lung biopsies were reviewed by a pathology core and 54 o

182 s were screened; 72 studies of BAL and 31 of lung biopsy were included.

183 Other procedures including lung biopsy were performed if clinically indicated.

184 is diagnosed with the use of transbronchial lung biopsies, which are invasive, expensive, and subjec

185 een validated by a preliminary test on human lung biopsy, which has confirmed the ex-vivo CK17 detect