ライフサイエンスコーパス: lyase

1 polyphenol oxidase and phenylalanine ammonia-lyase).

2 ning, by silencing a gene encoding a pectate lyase.

3 lfurase and not a type of cysteine sulfoxide lyase.

4 derivative 31 with the homodimeric human S1P lyase.

5 nservation, comprises the active site of the lyase.

6 tamate dehydrogenase and cystathionine gamma-lyase.

7 f structural similarity to that of human ADS lyase.

8 which encodes sphingosine-1-phosphate (S1P) lyase.

9 standing of the mechanism of this novel C-As lyase.

10 essential glycyl radical on pyruvate formate-lyase.

11 sentatives of a new family of polysaccharide lyases.

12 first one and to the sites found in other AP lyases.

13 only in plant cytochrome P450 hydroperoxide lyases.

14 Km values that have been noted for some DMSP lyases.

15 lycans are desulfated before cleavage by the lyases.

16 hibiting the enzyme, sphingosine-1-phosphate lyase 1 (SPL), has neuroprotective effects in Huntington

17 rasaccharide isolated from bacterial heparin lyase 1 digests of heparin that contains a Delta-2S-idur

18 sine kinase 1 and 2, sphingosine-1-phosphate lyase 1, and sphingosine-1-phosphate phosphatase 1 in no

19 Activity of isocitrate lyase AceA, an S-allylmercapto-modified candidate protei

20 reviously shown to modulate both ATP-citrate lyase (ACL) and AMP-activated protein kinase (AMPK) acti

21 ytaxin links kinesin-1 (KLC1) to ATP citrate lyase (ACL), a key enzyme for ACh synthesis, and transpo

22 tyl CoA (Ac-CoA), is produced by ATP-citrate lyase (ACLY) from mitochondria-derived citrate or by ace

23 is study, we report that nuclear ATP-citrate lyase (ACLY) is phosphorylated at S455 downstream of ata

24 ATP-citrate lyase (ACLY), a key enzyme for lipid synthesis, is frequ

25 ns in breast cancer, identifying ATP-citrate lyase (ACLY), an enzyme in the de novo lipogenesis pathw

26 ), acetyl-CoA carboxylase (ACC), ATP citrate lyase (ACLY)].

27 hemistry (nitrotyrosine, cystathionine gamma-lyase, activated caspase-3, and extravascular albumin),

28 activities of two enzymes: pyruvate formate lyase activating enzyme (coded by pflA) and pyruvate for

29 Pyruvate formate-lyase activating enzyme (PFL-AE) is a radical S-adenosyl

30 d by the radical SAM enzyme pyruvate formate-lyase activating enzyme.

31 etry and deletion analysis localized the dRP lyase active site to the C-terminal segment of Rev1's ca

32 uired the essential lysine-72 in the Polbeta lyase active site.

33 Indeed, the lyase-active enzyme has 3 orders of magnitude higher aff

34 d their DNA cleavage, DNA glycosylase and AP lyase activities in vitro at 37 degrees C.

35 th the glycosylase and apurinic/apyrimidinic lyase activities of OGG1.

36 led to the hypothesis that the isomerase and lyase activities performed by the MST enzymes are functi

37 Some DNA glycosylases possess AP lyase activities that nick the DNA strand at the deoxyri

38 ibited CYP17A1 17alpha-hydroxylase and 17,20-lyase activities with IC50 values in the nanomolar range

39 n induced tyrosine and phenylalanine ammonia-lyases activities.

40 DNA polymerases and a repair factor with dRP lyase activity (pol lambda, pol iota, pol theta and Ku70

41 se two proteins, which is critical for 17,20-lyase activity and androgen biosynthesis.

42 oves the entire 5'-AMP-dRP group through its lyase activity and flap endonuclease 1 (FEN1) excises th

43 t was deficient in soluble secreted alginate lyase activity and in digestion of and growth on alginat

44 icant decreases in the phenylalanine ammonia-lyase activity and significantly increases of peroxidase

45 13B01, exhibited high extracellular alginate lyase activity compared with other V. splendidus strains

46 temperature while another showed its weak AP lyase activity generates atypical ends.

47 heir ability to support BER in vitro The dRP lyase activity in both of these proteins was confirmed b

48 red a weak 5'-deoxyribose phosphate (5'-dRP) lyase activity in mouse Rev1 and demonstrated the enzyme

49 a small alpha-helical domain, whereas the AP lyase activity is found in a region formed by 12 tandem

50 The AP lyase activity is more coupled with glycosylase activity

51 However, the lyase activity of purified pol gamma was weak against th

52 roduct, while the synthase enzymes also have lyase activity that displaces pyruvate to form either sa

53 the faulty base and an apyrimidinic/apurinic lyase activity that introduces a single-strand DNA incis

54 We show that LpSpl possesses S1P lyase activity that was abrogated by mutation of the cat

55 rand break through its apurinic/apyrimidinic lyase activity to initiate base excision repair.

56 Glycosylase/apurinic lyase activity was reduced in Rad9(-/-) mouse ES and RAD

57 ylalanine ammonia-lyase and tyrosine ammonia-lyase activity were noted, which implies slight degradat

58 clude that zebrafish P450 17A2 is capable of lyase activity with the 17alpha-OOH steroids because it

59 rom phosphoserine (pSer), i.e., exhibit pSer lyase activity, a fundamentally new DNA-catalyzed reacti

60 eases in catalase and phenylalanine ammonium lyase activity.

61 ite may allow conformations that lead to the lyase activity.

62 d ability of b5 to selectively enhance 17,20-lyase activity.

63 ive for base excision but retains partial AP lyase activity.

64 s modification inhibits its phosphothreonine lyase activity.

65 EroS is a chondroitin lyase; although its substrate, chondroitin sulfate, was

66 ogenous H2 S production, cystathionine-gamma-lyase and 3-mercaptopyruvate sulphurtransferase, are exp

67 L-cysteine, and had both cysteine sulfoxide lyase and cysteine desulfurase activity.

68 ion in tumour cells by targeting ATP citrate lyase and fatty acid elongase 6, as well as impairing mi

69 y RNAi inhibits up-regulation of ATP citrate lyase and fatty-acid synthase.

70 The activities of pol beta lyase and FEN1 nucleotide excision were able to remove t

71 ly identified catalase-related hydroperoxide lyase and given the role of aldehydes in plant defense,

72 DddY is the only known periplasmic DMSP lyase and is present in beta-, gamma-, delta- and epsilo

73 In this study the genes encoding isocitrate lyase and malate synthase from Chlorogloeopsis fritschii

74 Transcript abundances for isocitrate lyase and malate synthase increased, and C. fritschii gr

75 When the genes encoding isocitrate lyase and malate synthase were expressed in Synechococcu

76 tudies reported the activities of isocitrate lyase and malate synthase, the key enzymes of the glyoxy

77 iquitinates and thus upregulates ATP citrate lyase and oxoglutarate dehydrogenase, two key enzymes th

78 hat two pectin modification genes, a pectate lyase and pectinesterase, are targets of both bHLH trans

79 ogenic enzyme 3-hydroxy-3-methylglutaryl-CoA lyase and promotes the formation of the ketone body acet

80 imultaneously, reduced phenylalanine ammonia-lyase and tyrosine ammonia-lyase activity were noted, wh

81 Ammonia-lyases and aminomutases are mechanistically and structur

82 In most cases, DMSP lyases and DMSP demethylases (DmdAs) have low substrate

83 ning method is demonstrated for both ammonia lyases and P450 monooxygenases expressed within live bac

84 nt enzymatic challenge to the polysaccharide lyases and sulfatases that mediate degradation.

85 no homology to the previously reported ulvan lyases and therefore are the first representatives of a

86 ynthase, acetyl-CoA carboxylase, ATP citrate lyase, and Glut-1 were significantly increased together

87 ches a biliverdin (BV) chromophore without a lyase, and has 642/670-nm excitation-emission peaks, a l

88 uch as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1.

89 microbes, to inhibit distinct microbial TMA lyases, and to both inhibit TMA production from physiolo

90 reports of the characterization of fungi C-S lyase at the molecular level.

91 ssing Brevibacterium linens methionine-gamma-lyase (BlMGL) produced the sulfur volatile compound dime

92 line not only induces choline-trimethylamine lyase but also genes encoding shell proteins for the for

93 e bHLH transcription factors and the pectate lyase, but not for the pectinesterase, complement water

94 l activation of Bhmt and cystathionine gamma-lyase by FOXA1.

95 l activation of Bhmt and cystathionine gamma-lyase by FOXA1.

96 of Lentinula edodes, and cysteine sulfoxide lyase (C-S lyase) is the key enzyme in this trait.

97 -acting glycoside hydrolases, polysaccharide lyases, carbohydrate esterases, and lytic polysaccharide

98 can achieve an appropriate conformation for lyase catalysis in this system that is precluded in the

99 Inhibition of cystathionine gamma-lyase causes rapid necrosis of TR/GR-null livers, indica

100 e (ALR), is a promiscuous cystathionine beta-lyase (CBL).

101 ion pathway (TSP) enzyme cystathionine gamma-lyase (CGL), resulting in increased hydrogen sulfide (H2

102 In contrast to N. ulvanivorans ulvan lyase, cleavage occurred specifically at the GlcUA resid

103 Bacterial DMSP lyases cleave DMSP, producing acrylate and dimethyl sulf

104 enzyme (coded by pflA) and pyruvate formate lyase (coded by pflB).

105 r metabolic disease; rather than disrupt ADS lyase, compounds that improve the stability the enzyme m

106 e of the 240-kilodalton Escherichia coli C-P lyase core complex (PhnG-PhnH-PhnI-PhnJ; PhnGHIJ), and s

107 a similar fold as the cyanobacterial T-type lyase CpcT from Nostoc sp. PCC7120 but overall is more c

108 However, it could assist the host lyase CpeS in its function by providing a pool of readil

109 ine beta-synthase (CBS), cystathionine gamma lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3-

110 identify the presence of cystathionine-gamma-lyase (CSE) and 3-mercaptopyruvate sulphurtransferase (3

111 he H2S-generating enzyme cystathionine gamma-lyase (CSE) by promoting its translation.

112 beta synthase (CBS) and cystathionine gamma lyase (CSE) enzymes.

113 and its synthetic enzyme cystathionine-gamma-lyase (CSE) is down-regulated in growth-restricted place

114 Cystathionine-gamma-lyase (CSE) is the predominant endothelial generator of

115 H2S-synthesizing enzyme cystathionine-gamma-lyase (CSE) normalized breathing in HO-2(-/-) mice.

116 n (PAG), an inhibitor of cystathionine-gamma-lyase (CSE), a key enzyme that produces intracellular H2

117 Both H2S production and cystathionine gamma-lyase (CSE), an H2S enzyme, levels were significantly de

118 with several blockers of cystathionine gamma-lyase (CSE), the enzyme responsible for sulphide synthes

119 or by overexpression of cystathionine gamma-lyase (CSE).

120 ne-ss-synthase (CBS) and cystathionine-gamma-lyase (CSE).

121 H2S)-synthesizing enzyme cystathionine-gamma-lyase (CSE).

122 ific inhibitors of 17alpha-hydroxylase/17,20-lyase (CYP17), the key enzyme which catalyzes the biosyn

123 erone, a steroidal 17alpha-hydroxylase/17,20-lyase (CYP17A1) inhibitor, blocks this synthetic process

124 bolic pathway, mediated by a cupin-like DMSP lyase, DddK, simultaneously shunts as much as 59% of DMS

125 Unlike other known DMSP lyases, DddY has not been classified into a protein supe

126 ing wild-type Polbeta than to cells with the lyase-defective form.

127 tability the enzyme may be used to treat ADS lyase deficiency disease.

128 e strong accumulation of APP and CTFs in S1P-lyase-deficient cells was reversed by selective mobiliza

129 An isocitrate lyase-deficient mutant of Mtb (Deltaicl1) exhibited a de

130 The reaction product generated by the lyase, Delta4,5-unsaturated uronic acid, is removed from

131 suggest that with further development, pSer lyase deoxyribozymes will have broad practical utility f

132 Two new pSer lyase deoxyribozymes, named Dha-forming deoxyribozymes 1

133 ferredoxin oxidoreductase / pyruvate-formate-lyase-dependent (rPFOR/Pfl) pathways.

134 first comprehensive report on LPS-degrading lyase derived from a Pseudomonas phage.

135 thening to approximately 140 nM for the full lyase domain (residues 2-87).

136 Lysines within the lyase domain are required for processive searching, reve

137 earching, revealing a novel function for the lyase domain of Pol beta.

138 ns a specific NLS sequence in the N-terminal lyase domain that promotes transport of the protein inde

139 on signal (NLS) may reside in the N-terminal lyase domain.

140 The production of diaminopropionate ammonia-lyase (DpaL) alleviated Dap toxicity in S. enterica by c

141 nd formation reaction and a PLP-mediated C-S lyase (EgtE) reaction results in a net sulfur transfer f

142 (hydrolysis of the N-glycosidic bond) and AP lyase (elimination of the 3'-phosphate of the AP-site).

143 mutant of long-chain base phosphate (LCB-P) lyase, encoded by the dihydrosphingosine-1-phosphate lya

144 dine biosynthetic pathway, argininosuccinate lyase-encoding, and ABC transporter-related genes as com

145 es its glycosylase and apyrimidinic/apurinic lyase enzymatic activities.

146 carbon nanotubes where phenylalanine ammonia-lyase enzyme was immobilized using nafion was characteri

147 Upon encountering dL, AP lyase enzymes such as DNA polymerase beta (Polbeta) form

148 P/ADP, phospholipid content, and ATP citrate lyase expression.

149 c context and modular structure of the ulvan lyase families identified to date, we propose that two u

150 al screening, we identified a polysaccharide lyase family 7 enzyme that is unique to V. splendidus 13

151 e crystal structure of a member of the novel lyase family revealed a catalytic domain that displays a

152 Here we have discovered a new polysaccharide lyase family that is specific for the l-rhamnose-alpha1,

153 ed by the pathogen (through formate hydrogen lyase [FHL] and Hyc) is insignificant in terms of provid

154 and biochemically characterized novel ulvan lyases from three Alteromonadales isolated bacteria.

155 ta catalyzes two key enzymatic steps: 5'-dRP lyase gap trimming and template-directed DNA synthesis.

156 sPAL4, a member of the phenylalanine ammonia-lyase gene family.

157 h Hemispheres were interrogated for alginate lyase gene homologue sequences and their genomic context

158 forms of RuBisCO, together with ATP citrate lyase genes in the rTCA cycle, increase with distance fr

159 xtracellular activity and lacks two alginate lyase genes present in V. splendidus 13B01.

160 tracts and high expression levels of pectate lyase genes suggest that the parasite contributes direct

161 ch is the substrate for the phycobiliprotein lyase GtCPES.

162 cterization of a eukaryotic phycobiliprotein lyase (GtCPES).

163 ogenic enzyme 3-hydroxy-3-methylglutaryl-CoA lyase (HMGCL).

164 on of the gene neighbourhood of the alginate lyase homologues revealed distinct patterns depending on

165 on of hexanal, probably due to hydroperoxide lyase (HPL) action on linoleyl hydroperoxides.

166 The His ammonia-lyase HutH binds Zn very tightly only in the presence of

167 t enzyme of the glyoxylate shunt, isocitrate lyase (ICL), may mediate survival of Mtb during the acut

168 Isocitrate lyase (ICL, types 1 and 2) is the first enzyme of the gl

169 the oligosaccharides obtained after heparin lyase III digestion of the polysaccharide indicated two

170 lade' ecotype contain only a single alginate lyase in a separate 7 kb island.

171 ATP and GTP, prompting us to investigate ADS lyase in C. neoformans.

172 Here, we report that ADE13 encodes ADS lyase in C. neoformans.

173 port that CLYBL operates as a citramalyl-CoA lyase in mammalian cells.

174 , partially selective inhibitor of CYP 17,20-lyase in the androgen signalling pathway, a validated th

175 n HAL, a gene that encodes histidine ammonia-lyase in the first step of histidine catabolism.

176 uccinate synthase (ASS1) and arginosuccinate lyase in UHCA.

177 arase and activate the cytosolic ATP-citrate lyase in vivo, acting as a direct regulator of carbon fl

178 rified EroS, and other bacterial chondroitin lyases induce S. rosetta mating at environmentally relev

179 hydroxycitrate, an inhibitor of ATP citrate lyase, induced the depletion of regulatory T cells (whic

180 l, nonsteroidal, reversible, selective 17,20-lyase inhibitor.

181 s an antimicrobial target, C. neoformans ADS lyase inhibitors may also serve as potential therapeutic

182 CutC choline trimethylamine-lyase is an anaerobic bacterial glycyl radical enzyme (G

183 We propose that a novel kind of ring-opening lyase is involved in the further catabolic pathway proce

184 la edodes, and cysteine sulfoxide lyase (C-S lyase) is the key enzyme in this trait.

185 hat acetyl-CoA synthase, rather than citrate lyase, is essential for acetyl-CoA synthesis in fission

186 cutC gene, encoding a choline-trimethylamine lyase, is essential for choline degradation to trimethyl

187 AlyA1, the only Z. galactanivorans alginate lyase known to be secreted in soluble form and to have a

188 We identified a L. edodes C-S lyase (Lecsl), cloned a gene of Csl encoded Lecsl and th

189 (HFD) results in suppression of ATP citrate-lyase levels in tissues such as adipose and liver, but t

190 igO, and LigL) and the glutathione-dependent lyase LigG provide new insights into the early and late

191 Enzymes of the class I lyase-like family catalyze the asymmetric addition of am

192 zymes such as CELLULASE5 (CEL5) and a pectin lyase-like gene, as well as the root cap regulators SOMB

193 ive targets of XRN4 and VCS in seeds (PECTIN LYASE-LIKE, ASPARTYL PROTEASE, DWD-HYPERSENSITIVE-TO-ABA

194 Two homologous ulvan lyases (long and short) were found in each of the bacter

195 the effector protein sphingosine-1 phosphate lyase (LpSpl) to target the host sphingosine biosynthesi

196 d propionate because of its methylisocitrate lyase (MCL) activity.

197 The organomercurial lyase MerB has the unique ability to cleave carbon-Hg bo

198 Methionine gamma-lyase (MGL) catalyzes the gamma-elimination of l-methion

199 ng-cleavage is achieved via hydratases, this lyase might represent a new ring-opening strategy for th

200 n the active site of N-acetylneuraminic acid lyase (NAL), and the resulting chemically modified enzym

201 N-Acetylneuraminic acid lyase (NAL, E.C. number 4.1.3.3) is a Class I aldolase t

202 nd prokaryotic bifunctional DNA glycosylases/lyases (NEIL1, Nei, Fpg, Nth, and NTH1) and apurinic/apy

203 Tryptophan lyase (NosL) is a radical S-adenosyl-l-methionine (SAM)

204 The major function of O-acetyl-Ser-(thiol) lyase (OAS-TL; EC 2.5.1.47) is the formation of l-Cys, b

205 es are: trace levels of OGDH, the isocitrate lyase of the glyoxylate shunt and an unanticipated sourc

206 either the glyoxylate shunt (via isocitrate lyase) or the TCA cycle (via isocitrate dehydrogenase (I

207 lavonoid compositions, phenylalanine ammonia lyase (PAL) activity and antioxidant capacity were evalu

208 consequent decrease in phenylalanine ammonia lyase (PAL) activity.

209 t approach by coupling phenylalanine ammonia lyase (PAL) amination with a chemoenzymatic deracemizati

210 ransient expression of phenylalanine ammonia-lyase (PAL) and stilbene synthase (STS) genes, followed

211 concurrent with higher phenylalanine ammonia lyase (PAL) enzyme activity leading to higher total phen

212 ic relevance, five new phenylalanine ammonia lyase (PAL) enzymes were discovered and characterised wi

213 gulation (1.4-fold) in phenylalanine ammonia lyase (PAL) gene expression and a consequent decrease in

214 gulation (1.4-fold) of phenylalanine ammonia lyase (PAL) gene expression and a consequent decrease in

215 Phenylalanine ammonia-lyase (PAL) is the first committed enzyme in the pathway

216 L-Phenylalanine ammonia-lyase (PAL) is the first enzyme in the biosynthesis of p

217 Phenylalanine ammonia-lyase (PAL) is the first enzyme of the general phenylpro

218 flowers expression of all three Phe ammonia lyase (PAL) isoforms that catalyze the non-oxidative dea

219 rismate via either the phenylalanine ammonia lyase (PAL) or the isochorismate synthase (ICS) catalyze

220 d 29W, the activity of phenylalanine ammonia lyase (PAL) was increased significantly (P<0.05) by 2.0

221 oxidase, catalase and phenylalanine ammonium lyase (PAL)) and non enzymatic (total phenolics, flavono

222 eptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL)) domains.

223 th the yeast enzyme of phenylalanine ammonia lyase (PAL).

224 enzymatic activity of phenylalanine ammonia-lyase (PAL).

225 les include the use of phenylalanine ammonia lyases (PALs), either alone or as a gateway to deracemiz

226 host defense responses, and secretes pectate lyase (Pel) to degrade the plant cell wall.

227 ycine alpha-hydroxylating monooxygenase) and lyase (peptidyl-alpha-hydroxyglycine alpha-amidating lya

228 and generates pyruvate, and pyruvate-formate lyase (PFL) converting pyruvate to formate and acetyl-Co

229 Pyruvate formate lyase (PFL) is a crucial enzyme for mixed acid fermentat

230 ate decarboxylase (PDC) and pyruvate formate lyase (PFL)-enzymes that catalyze the decarboxylation of

231 Further, two key genes encoding C-P lyase (phnJL, an important enzyme for dealkylation of MP

232 Family 2 polysaccharide lyases (PL2s) preferentially catalyze the beta-eliminati

233 e bifunctional enzyme adenylosuccinate (ADS) lyase plays a role in the formation of the key intermedi

234 ases PPA2105 and PPA1796 and the hyaluronate lyase PPA380 compared to that in untreated biofilms.

235 genic plants overexpressing methionine-gamma-lyase produced dimethyl sulfide.

236 ATP citrate-lyase produces acetyl-CoA in the nucleus and cytosol and

237 and P450 17A2 readily converted these to the lyase products in the absence of other proteins or cofac

238 ,17alpha-dihydroxypregnenolone to 16-hydroxy lyase products were also observed.

239 a single homotetrameric bifunctional ammonia-lyase (PTAL) among eight BdPAL enzymes in the model gras

240 a ferric peroxide pathway in the 17alpha,20-lyase reaction cannot be excluded.

241 The drug orteronel selectively blocked the lyase reaction of P450 17A1 but only in the case of Prog

242 ies under different in vitro conditions: C-S lyase reaction using either thioether or sulfoxide as a

243 zymatic mechanism of this unprecedented C-As lyase reaction will enhance our understanding of recycli

244 ha-hydroxylation and a subsequent 17alpha,20-lyase reaction with both Prog and Preg.

245 ha-hydroxylation and a subsequent 17alpha,20-lyase reaction, and several mechanisms have been propose

246 lpha-hydroxylation but does not catalyze the lyase reaction, even in the presence of cytochrome b5.

247 lternative ferric peroxide mechanism for the lyase reaction, or residues removed from the active site

248 c acid intermediate in the ergothioneine C-S lyase reaction.

249 estrates a remarkable C17-C20 bond cleavage (lyase) reaction, converting the 17-hydroxypregnenolone i

250 e and 17alpha-hydroxypregnenolone 17alpha,20-lyase reactions of human P450 17A1 and found incorporati

251 d progesterone and the subsequent 17alpha,20-lyase reactions to form dehydroepiandrosterone (DHEA) an

252 7A1 catalyzes both 17alpha-hydroxylation and lyase reactions with Prog and Preg, and P450 17A2 is mor

253 ferase and for the EutA ethanolamine ammonia-lyase reactivase.

254 ge P-HM1 encodes a putative phycobiliprotein lyase related to cyanobacterial T-type lyases, which fac

255 vities and is also unique by having three AP lyase repair sites in the same polypeptide.

256 tion by the 5-methylcytosine DNA glycosylase/lyase ROS1.

257 in an arsI gene, which encodes the ArsI C-As lyase, S. putrefaciens demethylated MAs(III) to As(III).

258 gulated, in part through the activity of S1P lyase (S1PL) which catalyses its irreversible degradatio

259 (-/-) mice), selenoprotein P (Sepp1) and Sec lyase (Scly), develop severe neurological dysfunction, n

260 recently reported that seviteronel, a CYP17 lyase-selective inhibitor, aedemonstrated a sustained re

261 vel interaction with sphingosine 1-phosphate lyase (SGPL1)-a key enzyme for the creation of the sphin

262 unction mutations in sphingosine-1-phosphate lyase (SGPL1).

263 e (PLP)-dependent domain, we termed cysteine lyase (SH) domain (LnmJ-SH), within PKS module-8 of LnmJ

264 Purified recombinant C. neoformans ADS lyase shows catalytic activity similar to its human coun

265 The 3rd AP lyase site is located in the 12th (HhH)2 domain.

266 Here, we show that Topo-V has three AP lyase sites.

267 A recombinant putative cystathionine gamma-lyase (smCSE) mineralizes CdS from an aqueous cadmium ac

268 show an O5 serotype-specific polysaccharide lyase specificity.

269 Sphingosine 1-phosphate (S1P) lyase (SPL) is an intracellular enzyme that mediates the

270 Spore photoproduct lyase (SPL) repairs 5-thyminyl-5,6-dihydrothymine, a thy

271 -specific knockout mouse models in which S1P-lyase (SPL), the enzyme responsible for irreversible S1P

272 enchymal S1P levels are kept low through S1P lyase (SPL)-mediated metabolism.

273 manipulating the S1P-metabolizing enzyme S1P lyase (SPL).

274 pha-OH product dissociates more prior to the lyase step.

275 zation of intermediates produced during this lyase step: an initial peroxo-anion intermediate, poised

276 biosynthesis pathway, ASL (adenylosuccinate lyase, Step 8) and ATIC (5-aminoimidazole-4-carboxamide

277 rocessivity of the 17alpha-hydroxylation and lyase steps.

278 its crystal structure, the first fungal ADS lyase structure determined, shows a high degree of struc

279 rryloxo active species of P450 17A1 when its lyase substrate is bound.

280 AP endonuclease, which generates the Polbeta lyase substrate, and they required the essential lysine-

281 e for the previously described carbon-sulfur lyase SUR1 in processing cysteine-isothiocyanate conjuga

282 monocots, PAL also displays tyrosine ammonia lyase (TAL) activity, leading to the formation of p-coum

283 om grasses can also possess tyrosine ammonia-lyase (TAL) activity, the reason for which has remained

284 erium expressed a single-surface endo-acting lyase that cleaved HS, reflecting its higher molecular w

285 ssion of YOR1 (exporter of PHS-1P) and DPL1 (lyase that degrades DHS-1P and PHS-1P) was increased.

286 action of pectin-methylesterase and pectate-lyase that possibly originated from a microbial source o

287 side hydrolases (GHs) and one polysaccharide lyase, the genes for which were transcribed at high leve

288 Native APC requires a lyase to incorporate phycocyanobilin.

289 lining the importance of chorismate pyruvate-lyase to initiate plastoquinone biosynthesis in cyanobac

290 re unmasked by a pre-treatment with alginate lyases to remove alginates.

291 the SaB4H, SaBIS, and phenylalanine ammonia lyase transcript levels preceded phytoalexin accumulatio

292 Expression of Bhmt and cystathionine gamma-lyase was decreased when mice were fed cholic acid but i

293 The first characterized ulvan lyase was identified in Nonlabens ulvanivorans, an ulvan

294 Alteromonas macleodii alginate lyases were predominantly detected in Atlantic Ocean met

295 The degradation of ulvan requires ulvan lyase, which catalyzes the endolytic cleavage of the gly

296 otein lyase related to cyanobacterial T-type lyases, which facilitate attachment of linear tetrapyrro

297 Two cytosol ATP-citrate lyases, which take part in the cycle of citrate synthesi

298 alginolytic system comprising five alginate lyases, whose expression was induced by alginate.

299 It is possible that the bacterium recruits lyases with highly plastic specificities and expresses a

300 e periplasm were degraded by a repertoire of lyases, with each enzyme displaying specificity for subs