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1 , it is unknown whether the SC is a blood or lymphatic vessel.
2 irregular, enlarged and excessively branched lymphatic vessels.
3 ndothelial growth factor receptor 3-positive lymphatic vessels.
4 larly distinct from those found in veins and lymphatic vessels.
5 ial cells, where it regulates development of lymphatic vessels.
6 es, such as lymphangiogenesis and obstructed lymphatic vessels.
7 oincidentally steering cell collectives into lymphatic vessels.
8 inhibition because it is highly expressed in lymphatic vessels.
9 valve (LVV) prevents backflow of blood into lymphatic vessels.
10 ity, to developing, resting and regenerating lymphatic vessels.
11 bioactive material to blood capillaries and lymphatic vessels.
12 s in the control of growth and remodeling of lymphatic vessels.
13 oietin 2 (Ang2) deficiency leads to abnormal lymphatic vessels.
14 recirculate to secondary lymphoid organs via lymphatic vessels.
15 ading to incomplete separation of venous and lymphatic vessels.
16 ssing Cyp26b1 had hypoplastic lymph sacs and lymphatic vessels.
17 e involved in lymphocyte trafficking via the lymphatic vessels.
18 nce of blood endothelial cells in peripheral lymphatic vessels.
19 od filled lymph sacs and hyperplastic dermal lymphatic vessels.
20 c process of intraluminal valve formation in lymphatic vessels.
21 levated tumor Adm expression led to enlarged lymphatic vessels.
22 ed macrophages upstream of blocked or absent lymphatic vessels.
23 e semipermeable barrier in blood vessels and lymphatic vessels.
24 r the remodeling and maturation of blood and lymphatic vessels.
25 rent molecular signature from blood and true lymphatic vessels.
26 he endothelial cells that line the blood and lymphatic vessels.
27 lve the dynamic pulsatile flow in collecting lymphatic vessels.
28 e as well as enlarged jugular lymph sacs and lymphatic vessels.
30 latures, the lack of functional intratumoral lymphatic vessels, abnormal tumor microenvironment, and
32 there is a marked decline in the density of lymphatic vessels, accompanied by accumulation of low-MW
33 manner; and induces ICAM-1 up-regulation on lymphatic vessels, allowing neutrophils to crawl along t
34 the tenet that orbital adipose tissue lacks lymphatic vessels and analyzed the clinicopathologic dif
36 rast agents to target cellular biomarkers in lymphatic vessels and can be detected by OCT using a pha
38 ntial differences between peripheral and CNS lymphatic vessels and examine the purported mechanisms o
39 hich directs egress from the skin via dermal lymphatic vessels and extravasation into the LN parenchy
40 ctor administration induced robust growth of lymphatic vessels and helped to preserve the structure o
41 xpressing the cognate chemokine receptors to lymphatic vessels and LEC permeability by inducing the d
42 ervations suggest that downstream mesenteric lymphatic vessels and lymph drainage into mesenteric lym
43 deficient mice develop dilated, blood-filled lymphatic vessels and lymphatic capillaries that are ect
44 e causes defects in maturation of collecting lymphatic vessels and lymphatic valve formation, uncover
45 nt, treatment with DMH1 altered fibroblasts, lymphatic vessels and macrophages to be less tumor promo
46 s been widely used to conveniently visualize lymphatic vessels and other Prox1-expressing tissues suc
47 entry of tissue-infiltrated neutrophils into lymphatic vessels and subsequent crawling along the lumi
48 escribe the recently characterized meningeal lymphatic vessels and their role in drainage of the brai
49 hat DCs docked to the basolateral surface of lymphatic vessels and transited to the lumen through hya
50 uable tool for intravital imaging of corneal lymphatic vessels and valves and can be used to study pa
51 ins tissue fluid balance, and dysfunction of lymphatic vessels and valves causes human lymphedema syn
52 ef episode of initial inflammation regressed lymphatic vessels, and a significant increase in CD11b(+
53 ted in increased LEC proliferation, enlarged lymphatic vessels, and abnormal lymphatic vessel morphog
54 d a pure committed LEC phenotype, formed new lymphatic vessels, and expressed lymphangiogenic factors
55 e amount of the inoculum within the lumen of lymphatic vessels, and the timing of the transport indic
56 ria for distinguishing the DT from blood and lymphatic vessels; and (c) presence of a DT wall organiz
64 k corneal transplantation in which blood and lymphatic vessels are present and treatment begins at th
66 iated with increased immune suppression, yet lymphatic vessels are required for fluid drainage and im
69 mediastinal draining lymph nodes; increased lymphatic vessel area; and graft infiltration of CD4(+),
70 Here, we identified LECs, which line the lymphatic vessels, as a niche for Mycobacterium tubercul
72 promoter to drive strong EGFP expression in lymphatic vessels at all stages of development and in ad
73 pressed throughout the developing mesenteric lymphatic vessels at E16.5, and that, by E18.5, Notch1 e
74 the arrest of tumor cells in the collecting lymphatic vessels at the junction with the lymph node su
75 ransit of leukocytes and tumor cells through lymphatic vessels based largely onin vitrostudies with r
77 mary endothelial cells from dermal blood and lymphatic vessels (blood vascular endothelial cells and
79 r LNs of OVA/CFA-immunized mice not only via lymphatic vessels but also from blood, across high endot
80 issue or invade distant organs via blood and lymphatic vessels, but the role of lymphangiogenesis in
84 EMT cells preferentially migrated toward lymphatic vessels compared with blood vessels, both in v
86 to elevated downstream pressure, collecting lymphatic vessels containing one valve (incomplete lymph
87 , double-blinded clinical trial: conversely, lymphatic vessel contraction frequency was increased and
90 GFC from the adenoviral vector had increased lymphatic vessel density and more metastases in lymph no
91 luded paw thickness, lymphatic drainage, and lymphatic vessel density as measured by podoplanin immun
92 by indocyanine green clearance and increased lymphatic vessel density as measured by podoplanin immun
94 cavenging receptor, ACKR2, display increased lymphatic vessel density in a range of tissues under res
96 ination of embryonic skin revealed that this lymphatic vessel density phenotype is developmentally es
97 rtum breast cancers have increased peritumor lymphatic vessel density that correlates with increased
100 ion in obesity is characterized by decreased lymphatic vessel density, decreased collecting lymphatic
101 lymphatic vessel pumping capacity, decreased lymphatic vessel density, decreased lymphatic migration
102 duces lymphatic leakiness, decreases initial lymphatic vessel density, impairs collecting vessel pump
103 EPR effect were evaluated, such as blood and lymphatic vessel density, intratumoral hypoxia, and the
104 us lymphatic collecting vessel pumping rate, lymphatic vessel density, lymphatic leakiness, and lymph
106 er, we have recently discovered that corneal lymphatic vessels develop luminal valves as lymphangioge
108 teraction represents a critical regulator of lymphatic vessel development and the transcriptional net
110 owerful model organism that enables study of lymphatic vessel development using high-resolution imagi
111 investigated the functional role of flow in lymphatic vessel development using mice deficient for th
112 evelopment, arterial mural cell coating, and lymphatic vessel development, required sphingosine 1-pho
113 ation but also plays a central role in blood-lymphatic vessel development, tumor metastasis, and prev
117 through cell-type-specific networks and that lymphatic vessel dilation occurs secondarily to increase
118 Surprising recent evidence suggests that lymphatic vessels do not merely represent passive channe
120 ased blood vessel permeability and decreased lymphatic vessel drainage during inflammation, highlight
126 blation of Hdac3 in mice led to blood-filled lymphatic vessels, edema, defective lymphovenous valve m
127 onstitute the luminal layer of all blood and lymphatic vessels, emerge de novo from the mesoderm in a
128 uding blood vessel endothelial cells (BECs), lymphatic vessel endothelial cells (LECs), bone marrow-d
129 milar to lymphatic regression, the number of lymphatic vessel endothelial hyaluronan receptor 1 (LYVE
130 and lymphatic markers including podoplanin, lymphatic vessel endothelial hyaluronan receptor 1 (LYVE
131 atic endothelial cell markers podoplanin and lymphatic vessel endothelial hyaluronan receptor 1 (LYVE
132 n vivo imaging of the expression profiles of lymphatic vessel endothelial hyaluronan receptor 1 (LYVE
133 n of Chd4 specifically in cells that express lymphatic vessel endothelial hyaluronan receptor 1 (LYVE
134 al sodium channel gamma expression, and more lymphatic vessel endothelial hyaluronan receptor 1-posit
136 Immunohistochemistry was performed with lymphatic vessel endothelial hyaluronate receptor 1 (LYV
137 2-FLAIR and T1-weighted black-blood imaging, lymphatic vessels enhance with gadobutrol, a gadolinium-
138 onstrates definitively that mouse collecting lymphatic vessels exhibit autonomous, large-amplitude co
139 Hdac3-deficient lymphovenous valves and lymphatic vessels exhibited reduced expression of the tr
140 ease growth factors such as VEGF-C to induce lymphatic vessel expansion (lymphangiogenesis) in primar
142 reater than that of arterioles or collecting lymphatic vessels exposed to uniform increases in pressu
146 cessary to match a unique need of intestinal lymphatic vessels for both continuous maintenance, due t
147 ector CD8(+) T cells accumulated at efferent lymphatic vessels for egress, whereas high affinity-stim
148 w is essential for the remodeling of primary lymphatic vessels, for ensuring the proper distribution
149 Taken together, these results indicate that lymphatic vessel formation after lung transplantation me
150 Cui et al. provide compelling evidence that lymphatic vessel formation improves lung allograft survi
151 g hPSCs, and that these cells are potent for lymphatic vessel formation in vivo and wound healing.
152 underlying molecular mediators of blood and lymphatic vessel formation within the orbital fat also w
153 portunity to study the mechanisms underlying lymphatic vessel formation, remodeling and function in a
154 lls is sufficient to inhibit tumor blood and lymphatic vessel formation, thus leading to a significan
155 of sunitinib-treated patients and increased lymphatic vessels found in 70% of neoadjuvant treated pa
156 ctly by isolating and cannulating collecting lymphatic vessels from genetically modified mice for ex
158 e next addressed whether RCT was mediated by lymphatic vessels from the aortic wall by loading the ao
159 lymphatic endothelium, we excised collecting lymphatic vessels from the popliteal fossa of mice and r
160 hether CCB treatment is detrimental to human lymphatic vessel function and thereby exacerbates oedema
161 when extrapolating in vitro observations of lymphatic vessel function to the clinical situation, as
162 1 (-/-) Apoe (-/-) mice showed impairment of lymphatic vessel function with decreased drainage of int
167 lpha (TNF-alpha) coupled with VEGFA elicited lymphatic vessel genesis significantly above either fact
169 pes simplex virus type-1 (HSV-1) induces new lymphatic vessel growth (lymphangiogenesis) in the corne
170 The secreted protein CCBE1 is required for lymphatic vessel growth in fish and mice, and mutations
171 endothelial cell tips are a prerequisite for lymphatic vessel growth in vivo, and a VEGFR3 blockade c
173 ways for the specific growth of arteries and lymphatic vessels have been identified, but the mechanis
174 es of the glymphatic system and of meningeal lymphatic vessels have generated a lot of excitement, al
175 entery, TLOs are positioned along collecting lymphatic vessels in a manner expected to affect deliver
176 primes directly the neutrophils to enter the lymphatic vessels in a strictly CCR7-dependent manner; a
182 Here, we report the existence of meningeal lymphatic vessels in human and nonhuman primates (common
183 ata that directly address the exact roles of lymphatic vessels in lung allograft function and surviva
184 n of vascular endothelial cadherin (CDH5) on lymphatic vessels in mice and in human intestinal lympha
185 gans with the proposed function of meningeal lymphatic vessels in neurological disorders, specificall
186 intrinsic, active contractions of collecting lymphatic vessels in relation to their ability to active
188 ively transferred lymphocytes accumulated at lymphatic vessels in the lymph nodes of ADAP-deficient m
190 locally that are involved in the genesis of lymphatic vessels in the normally avascular cornea in re
191 es, we performed a comprehensive analysis of lymphatic vessels in the skin of type 2 diabetic versus
194 fied an important role for disturbed flow in lymphatic vessels, in which it cooperates with the trans
195 nd allowed a convenient visualization of all lymphatic vessels, including those in the central nervou
196 ogical detection of tumor cells in blood and lymphatic vessels indicated both hematogenous and lympha
197 ing depth of tumor infiltration (P = 0.004), lymphatic vessel infiltration (P = 0.002), tumor differe
199 trast, there was an initial robust growth of lymphatic vessels into the cornea of HSV-1-infected CD11
200 usly shown that HSV-1 elicits the genesis of lymphatic vessels into the cornea proper through epithel
202 ltration of the submucosa (P=0.002) but also lymphatic vessel invasion (P<0.001), multifocal tumor gr
203 sport of interstitial fluid and solutes into lymphatic vessels is important for maintaining interstit
205 mplex, consisting of fin muscles, bones, and lymphatic vessels, is involved in the hydraulic control
207 hatic trafficking of immune cells, increased lymphatic vessel leakiness and changes in the gene expre
208 mphatic migration of immune cells, increased lymphatic vessel leakiness and decreased expression of l
212 y found in the exocrine pancreas, with small lymphatic vessels located close to and around acini.
213 ovenous malformation (CM-AVM) is a blood and lymphatic vessel (LV) disorder that is caused by inherit
219 Whereas in IL-7Ralpha(-/-) mice, dermal lymphatic vessels (LVs) were abnormally organized and ly
221 and displaying complete aplasia of the dural lymphatic vessels, macromolecule clearance from the brai
222 ffusion (chylothorax) frequently accompanies lymphatic vessel malformations and other conditions with
224 of lymphovenous hemostasis and its effect on lymphatic vessel maturation and synthesizes the outstand
225 cillatory shear stress (OSS), which promotes lymphatic vessel maturation, triggers Wnt/beta-catenin s
226 mphangiogenesis and identifies a property of lymphatic vessel memory in response to recurrent inflamm
228 er a priming mechanism to facilitate a rapid lymphatic vessel memory response: a potential important
232 Here we report the surprising finding of a lymphatic vessel network in the dura mater of the mouse
238 mock-infected inoculum was identified within lymphatic vessels of the lamina propria and in spaces of
240 ss immune function, I reevaluate the passive lymphatic vessel paradigm and discuss its relevance to a
242 Importantly, FOXC2 completely rescues the lymphatic vessel patterning defects in mice lacking beta
244 s with progression and metastasis, and local lymphatic vessels play complex and poorly understood rol
246 obese mice had markedly decreased collecting lymphatic vessel pumping capacity, decreased lymphatic v
247 mphatic vessel density, decreased collecting lymphatic vessel pumping frequency, decreased lymphatic
252 Pecam1 deletion in mice results in impaired lymphatic vessel remodeling, including abnormal valve mo
253 d sets functionally related to inflammation, lymphatic vessel remodeling, lymphangiogenesis, and lipi
255 leads to the question of how each segment of lymphatic vessel responds to local signals that can cont
258 ester human skin, the phenotype of blood and lymphatic vessels roughly resembles the one in adult ski
259 Their results support the concept that the lymphatic vessel route is critical for RCT from atherosc
261 constriction was transmitted to the upstream lymphatic vessel segment even though it was protected fr
263 ear the surgery site, whereas the collecting lymphatic vessels showed a gradually decreasing contract
264 and popliteal nodes with draining popliteal lymphatic vessel significantly decreased the presence of
265 ntal and/or functional defects affecting the lymphatic vessels: sporadic and familial forms of primar
267 cells (LECs), consistent with an increase in lymphatic vessel sprouting in a three-dimensional lympha
270 mal epithelial cells, fibroblasts, blood and lymphatic vessels, structural components, and infiltrati
271 sity, suggesting neovascularization and rare lymphatic vessels suggestive of limited lymphangiogenesi
272 ro-lymphangiogenic macrophages to developing lymphatic vessel surfaces is increased in ACKR2-deficien
274 E-1), and podoplanin mRNA and contained more lymphatic vessels than tissue from patients without UFF.
275 However, cellular and Ag trafficking in the lymphatic vessels that connect an i.m. injection site wi
276 uced de novo generation of deep intratumoral lymphatic vessels that were highly permissive to invasio
277 s then leave the lymph node via the efferent lymphatic vessel to perform their systemic function.
279 )(-/-) and inducible NO synthase (iNOS)(-/-) lymphatic vessels to controlled pressure steps followed
281 Like many cancers, mammary carcinomas use lymphatic vessels to disseminate, and numerous clinical
282 of fluid pressure environments, allowing the lymphatic vessels to provide pumping when needed but rem
284 drenaline did not elicit normal increases in lymphatic vessel tone when maximal constriction was redu
289 t innate lymphoid cells that had invaded the lymphatic vessel wall, suggesting these cells may be med
290 l coverage (SMC coverage) of CLEC2-deficient lymphatic vessels was both premature and excessive, a ph
291 crofluorometric technique adapted to in vivo lymphatic vessels, we determined that rat mesenteric col
292 mune cells from the lymphoid organs into the lymphatic vessels; we investigated its role in the respo
294 nd in turn relies on an absence of blood and lymphatic vessels, which is remarkable given the cornea'
295 xistence of 'suction pressure' in collecting lymphatic vessels, which manifests as a transient drop i
296 mor blood vessels induced the development of lymphatic vessels, which may have contributed to the tre
297 the proliferation of LECs and the number of lymphatic vessels, while elevated tumor Adm expression l
298 easurement of the function of tumor-draining lymphatic vessels, with potential applications in the de
299 well as rare staining of podoplanin-positive lymphatic vessels within acutely inflamed orbital fat ti
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