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1 wo of two mixed cellularity, and two of four lymphocyte depletion).
2 251-infected macaques with or without CD8(+) lymphocyte depletion.
3 al hospitalization and causes more sustained lymphocyte depletion.
4 of these properties to in vivo CD4-positive lymphocyte depletion.
5 suppression in sepsis by inducing widespread lymphocyte depletion.
6 Some mice showed marked splenic lymphocyte depletion.
7 MS suppression following alemtuzumab-induced lymphocyte depletion.
8 antibody that causes profound and sustained lymphocyte depletion.
9 mmunological deficits because of protein and lymphocyte depletion.
10 the CNS, and rituximab leads to prolonged B-lymphocyte depletion.
11 l transplant patients after treatment with B-lymphocyte depletion.
12 ot recapitulate the viral dynamics of CD8(+) lymphocyte depletion.
13 R3-173 mAb were not associated with effector lymphocyte depletion.
14 iciency virus), or iatrogenic (chemotherapy) lymphocyte depletion.
15 tuzumab subjects despite profound, prolonged lymphocyte depletion.
16 occurred concomitantly with acute gut CD4 T-lymphocyte depletion.
17 orrelate with the degree of preceding CD8+ T lymphocyte depletion.
18 B cell levels following chemotherapy-induced lymphocyte depletion.
19 disruption, cell death, and ultimately, CD4+ lymphocyte depletion.
20 67 (47%) of 143 mixed cellularity, and all 5 lymphocyte depletion.
21 lar sclerosis (132), mixed cellularity (34), lymphocyte depletion (2), and unclassified types (5), al
22 l cycling in response to alemtuzumab-induced lymphocyte depletion, a phenomenon that is driven by hig
24 response in SHIV-immunized monkeys by CD8(+) lymphocyte depletion, an intervention that abrogated SHI
25 ting virus, KU-1, that caused rapid CD4(+) T-lymphocyte depletion and AIDS-like illness in monkeys
26 nic viruses (SHIV-89.6P) inducing rapid CD4+ lymphocyte depletion and AIDS-like illness in rhesus mon
27 s tolerated rituximab well, achieved swift B-lymphocyte depletion and complete clinical remission (ac
29 R) or more experienced irreversible CD4(+) T lymphocyte depletion and developed clinical disease requ
30 IFN-gamma and Irgm1 were 'rescued' from the lymphocyte depletion and greater mortality that occurs i
31 ompartments and possible mechanisms of CD4 T-lymphocyte depletion and immune dysfunction in simian AI
32 deaminase activity (ADA) activity results in lymphocyte depletion and in severe combined immunodefici
33 he absence of adenosine deaminase results in lymphocyte depletion and in severe combined immunodefici
34 on, providing a potential mechanism by which lymphocyte depletion and repopulation could reduce the r
35 l was insensitive to either CD8(+) or CD4(+) lymphocyte depletion and, at necropsy, cell-associated S
36 Global suppression of the immune system via lymphocyte depletion and/or immunosuppressive drugs can
37 spleen, lungs, and regional lymph nodes and lymphocyte depletion and/or lymphocytolysis in the splee
38 5 nodular sclerosis, 16 mixed cellularity, 5 lymphocyte depletion, and 5 unclassified) and in 66% of
39 omic relationship between virus replication, lymphocyte depletion, and cytokine gene expression level
40 39-infected rhesus macaques underwent CD8(+) lymphocyte depletion, and RNA from whole blood was obtai
41 ells in 30 of 35 cases of nodular-sclerosis, lymphocyte-depletion, and mixed-cellularity Hodgkin's di
43 -inclusive regimens has led to studies using lymphocyte depletion as induction and maintenance therap
44 cells in vivo, with the pattern of CD4(+) T lymphocyte depletion being inextricably linked to chemok
45 ata reveal a differential impact of CD8(+) T lymphocyte depletion between controller and progressor S
46 ffects of rATG may occur not only because of lymphocyte depletion but also enhanced Treg cell number
48 tetraprolin-deficient mice after cytotoxic T lymphocyte depletion, but also in WSX-1/tristetraprolin
50 e to tolerance induction seen after subtotal lymphocyte depletion can be attributed to alterations in
51 ystander CD4 T cells is a major mechanism of lymphocyte depletion caused by X4 HIV-1 strains but is o
52 to three consecutive cycles until achieving lymphocyte depletion (CD4(+) count < 200/muL) or progres
54 poptosis induction in the progressive CD4(+)-lymphocyte depletion characteristic of HIV-1 pathogenesi
56 tion of immunoregulation, rather than simple lymphocyte depletion, contributes to the therapeutic eff
58 infected perinatally with HIV, a pattern of lymphocyte depletion develops that resembles the pattern
59 d (0.03 mg/kg per day), there was a profound lymphocyte depletion down to about 30% of pretransplant
61 letion, we investigated the effect of CD8(+) lymphocyte depletion during primary SIV infection on CD4
62 udies indicate transient BAFFR-Fc-mediated B lymphocyte depletion elicits long-term T1D protection by
64 T-cell distribution were more important than lymphocyte depletion for controlling the blood cell leve
69 rmed experiments of in vivo CD4(+) or CD8(+) lymphocyte depletion in 2 nonhuman primate species, rhes
72 e failure as a generalized mechanism for CD4 lymphocyte depletion in HIV-1 infection, as alpha1 circl
73 erential rates of AIDS development and/or T4 lymphocyte depletion in HIV-1-infected individuals remai
80 This phase 2 study evaluated the role of B-lymphocyte depletion in patients with type 1 diabetes.
82 (HK/486) (nonlethal) virus and monitored for lymphocyte depletion in the blood, lungs, and lymphoid t
85 on, we previously showed that peritransplant lymphocyte depletion induces rapid memory T cell prolife
91 Recovery of lymphocyte populations after lymphocyte depletion is implicated in therapeutic immune
94 tory to conventional therapy suggests that B lymphocyte depletion may be a safe, effective, mechanism
95 progression of CNS neuronal injury in a CD8 lymphocyte depletion model of neuroAIDS in SIV-infected
98 croenvironment may account for the selective lymphocyte depletion observed in this model of familial
100 cytes, follicular hyperplasia of the spleen, lymphocyte depletion of mesenteric lymph nodes, intersti
101 d immunodeficiency associated with stringent lymphocyte depletion of the graft appears to strongly pr
105 fected cells were highly associated with CD4 lymphocyte depletion (p = 0.00001 and p = 0.003, respect
106 g tolerogenic cytokine administration and/or lymphocyte depletion prior to oral antigen-specific immu
111 e new findings strongly indicate that CD4(+) lymphocyte depletion seen in AIDS is primarily a consequ
115 control of postchallenge viremia after CD8+ lymphocyte depletion suggests that both humoral and cell
116 ce for the safety and possible efficacy of B lymphocyte depletion therapy in SLE to justify a formal
117 d in nine rhesus monkeys that received CD3 T-lymphocyte depletion therapy with immunotoxin on the day
118 ss the clinical and serologic responses to B lymphocyte depletion therapy with rituximab in patients
120 -F/R safely provides tumor cytoreduction and lymphocyte depletion, thereby offering a bridge to RIC-a
123 icular those specific for donor HLA, after B-lymphocyte depletion treatment in renal transplant recip
124 ously demonstrated that induction therapy by lymphocyte depletion, using alemtuzumab (anti-human CD52
125 l mediator of the inflammatory response, and lymphocyte depletion via apoptosis may be an important m
134 Histological examination showed diffuse lymphocyte depletion, which was most striking in the CD4
135 both arms was to achieve rapid and effective lymphocyte depletion while simultaneously allowing reduc
136 therefore performed a trial to determine if lymphocyte depletion with alemtuzumab combined with DSG
138 , an adenosine deaminase inhibitor, leads to lymphocyte depletion with low risk of myelosuppression.
140 atients treated with 2-CdA showed peripheral lymphocyte depletion without a significant reduction in
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