ライフサイエンスコーパス: lymphocyte homing

1 edicted to promote the overall efficiency of lymphocyte homing.

2 ode high endothelial venules does not affect lymphocyte homing.

3 synthesis of L-selectin ligands required for lymphocyte homing.

4 s in venules at sites of inflammation and in lymphocyte homing.

5 te extravasation in inflammation, and faulty lymphocyte homing.

6 our understanding of how L-selectin mediates lymphocyte homing.

7 f the existence of a biological rheostat for lymphocyte homing.

8 ter receptor a4beta7 on lymphocytes controls lymphocyte homing.

9 ion molecules in regulating inflammation and lymphocyte homing.

10 hold for the amount of L-selectin needed for lymphocyte homing.

11 s in lymphocyte rolling and is essential for lymphocyte homing.

12 icking in HEV, accounting for the diminished lymphocyte homing.

13 environment also plays a role in determining lymphocyte homing.

14 stent with a selective role for CCR4 in skin lymphocyte homing.

15 HEV-specific L-selectin ligands required for lymphocyte homing.

16 to the control of leukocyte recruitment and lymphocyte homing.

17 chronic inflammation and dendritic cell and lymphocyte homing.

18 mutant mice displayed a severe impairment in lymphocyte homing and a compromised contact hypersensiti

19 irst direct evidence of CCR10 involvement in lymphocyte homing and accumulation in vivo, and demonstr

20 ion profiles and flow-cytometric analysis of lymphocyte homing and cell proliferation markers demonst

21 e-binding molecules involved in constitutive lymphocyte homing and chronic and acute inflammation pro

22 nt B cells and deregulated genes involved in lymphocyte homing and dissemination of human lymphomas.

23 DOCK2 plays a critical role in lymphocyte homing and immunological synapse formation by

24 mmation and therefore influences patterns of lymphocyte homing and inflammation.

25 ), a lectin-like adhesion molecule, mediates lymphocyte homing and leukocyte accumulation at sites of

26 does not appear to play an essential role in lymphocyte homing and leukocyte extravasation or in T ce

27 hat LFA-1 does not play an essential role in lymphocyte homing and leukocyte extravasation.

28 Here we identify the gene encoding the lymphocyte homing and migration protein CD44 as a target

29 Basal lymphocyte homing and neutrophil recruitment to inflamed

30 sulfo sialyl Lewis X in L-selectin-dependent lymphocyte homing and recruitment.

31 ouble null mice exhibited a markedly reduced lymphocyte homing and reduced lymphocyte counts as a res

32 o function of endothelial heparan sulfate in lymphocyte homing and stimulation of the immune response

33 HEV-specific L-selectin ligands required for lymphocyte homing and suggest that LSST and Core2GlcNAcT

34 attributable to a combination of blockage of lymphocyte homing and the release of thymocytes from the

35 sues expresses tissue-specific receptors for lymphocyte homing, and recent work utilizing phage homin

36 in, fibrotic diseases, cholestatic pruritus, lymphocyte homing, and thrombotic diseases by producing

37 eptor activities, leukocyte trafficking, and lymphocyte homing are controlled prominently but incompl

38 Certain features of lymphocyte homing are maintained in lymphoma recruitment

39 w current thinking about the ATX/LPA axis in lymphocyte homing, as well as in models of allergic airw

40 tive gene splicing, regulates hematopoiesis, lymphocyte homing, B-lineage cell growth, and angiogenes

41 L-selectin mediates lymphocyte homing by facilitating lymphocyte adhesion to

42 L-selectin mediates lymphocyte homing by facilitating lymphocyte adhesion to

43 L-selectin mediates lymphocyte homing by facilitating lymphocyte adhesion to

44 Inhibition of lymphocyte homing by treatment with FTY720 did not impai

45 Moreover, in an in vivo model of lymphocyte homing, cells expressing only the truncated f

46 independently also from major shifts in the lymphocyte-homing chemokines, CXCL12, CXCL13, and CCL19/

47 dressin required for Peyer's patch-selective lymphocyte homing during ontogeny of the murine intestin

48 rked by up-regulation of genes that regulate lymphocyte homing, followed by quenching of genes that i

49 ial venules, specialized vessels involved in lymphocyte homing from the blood into lymph nodes and Pe

50 Selective lymphocyte homing from the blood into tissues is control

51 o intact mucosal immunity through effects on lymphocyte homing, IgA production, and resistance to ant

52 1 receptor internalization in HCC cells or T lymphocyte homing in immunocompetent mice.

53 ed as critical mediators of skin-specific TH lymphocyte homing in mice and humans.

54 on of 6-sulfo sLe(x) carried on N-glycans to lymphocyte homing in mice.

55 evidence for the importance of N-glycans in lymphocyte homing in mouse and indicate that this depend

56 f alpha(4)beta(7), which might contribute to lymphocyte homing in the absence of L-Sel.

57 zed alphaLbeta2-dependent adhesion in vitro, lymphocyte homing in vivo, and firm adhesion but not rol

58 at potentially regulate L-selectin-dependent lymphocyte homing in vivo.

59 contributed in vivo to O-glycan-independent lymphocyte homing in wild-type and mutant mice.

60 echanism of action, i.e. chemokine-dependent lymphocyte homing into secondary lymphoid organs associa

61 s and natural killer T cells, is involved in lymphocyte homing into the aortic wall and modulates the

62 of beta7-deficient mice, demonstrating that lymphocyte homing is a competitive process and that inte

63 ces reveal that the exquisite specificity of lymphocyte homing is determined by combinatorial "decisi

64 Lymphocyte homing is mediated by specific interaction be

65 Lymphocyte homing is mediated by specific interactions b

66 tion, an analogous function of VE-JAM during lymphocyte homing is plausible.

67 s article a review of the molecular basis of lymphocyte homing is presented, and mechanisms by which

68 Although the role of CCL28 in lymphocyte homing is well established, direct in vivo ev

69 During lymphocyte homing, L-selectin mediates the tethering and

70 ICAM-2 is not essential for lymphocyte homing or the development of leukocytes, with

71 , Th1 cell lines and clones, we compared the lymphocyte homing patterns of a Chlamydia-specific, prot

72 is an essential regulator of hematopoiesis, lymphocyte homing, pre-B-cell growth, and angiogenesis.

73 R4, its ligand CCL17/TARC, and the cutaneous lymphocyte-homing process.

74 This lymphocyte "homing" process disperses the immunologic re

75 The expression of the lymphocyte homing receptor and activation marker L-selec

76 In this study, we examined lymphocyte homing receptor and vascular addressin expres

77 resulted in more pronounced shedding of the lymphocyte homing receptor CD62L and in increased progra

78 MAdCAM-1 binds the lymphocyte homing receptor for Peyer's patches, the inte

79 The lymphocyte homing receptor integrin alpha(4)beta(7) is u

80 Functional analyses revealed that the lymphocyte homing receptor L-selectin (CD62L) is the key

81 ress enhances the function of the L-selectin lymphocyte homing receptor through an interleukin-6 (IL-

82 inally identified as the lymph node-specific lymphocyte homing receptor, L-selectin has also been sug

83 These findings suggest expression of lymphocyte homing receptors by B cells and vascular addr

84 Identification of lymphocyte-homing receptors on L-Sel(-/-) and L-Sel(+/+)

85 Recent reports that some lymphocyte homing-receptors are shared by the liver and

86 Blocking lymphocyte homing rescued bleeding, indicating that PDPN

87 ibutes to HEV-born L-selectin ligands, since lymphocyte homing retained in FucT-VII(-/-) mice is revo

88 ting lymphocytes and increased expression of lymphocyte-homing signals in the metastatic tumors.

89 for CD44 and CD62L expression for mediating lymphocyte homing, thus permitting the development of au

90 ve T and B cells and play a critical role in lymphocyte homing to appropriate zones within secondary

91 ow unappreciated dominant role for VCAM-1 in lymphocyte homing to BM.

92 le (HEV) gene that is crucial for regulating lymphocyte homing to lymph nodes (LN).

93 Although the requirements for T lymphocyte homing to lymph nodes (LNs) are well studied,

94 Lymphocyte homing to lymph nodes and Peyer's patches is

95 Notably, lymphocyte homing to lymph nodes was decreased by 30%.

96 Understanding the molecular basis of lymphocyte homing to lymphoid organs was originally a pr

97 he vascular addressins that direct selective lymphocyte homing to lymphoid organs.

98 Their interaction directs lymphocyte homing to mucosa-associated lymphoid tissues.

99 egrin alpha4beta7 plays an important role in lymphocyte homing to mucosal lymphoid tissues and has be

100 hibit binding to MAdCAM in vitro and inhibit lymphocyte homing to murine intestines in vivo.

101 teraction of alpha4beta7 with MAdCAM inhibit lymphocyte homing to murine intestines without effecting

102 -79 anti-PNAd mAb in vivo effectively blocks lymphocyte homing to mutant PPs.

103 Lymphocyte homing to normal tissues and recruitment to i

104 aracterize the adhesion cascade that directs lymphocyte homing to peripheral lymph nodes (PLNs), we i

105 ne alone leads to only partial impairment of lymphocyte homing to peripheral lymph nodes and moderate

106 gh endothelial venules, considerably reduced lymphocyte homing to peripheral lymph nodes and reduced

107 a 7 integrins and L-selectin account for all lymphocyte homing to Peyer's patches, but P-selectin-dep

108 a 4 integrins, which play a critical role in lymphocyte homing to Peyer's Patches, made no significan

109 Despite this, KLF3 overexpression abolishes lymphocyte homing to Peyer's patches, much like beta7 de

110 st a novel P-selectin dependent mechanism of lymphocyte homing to Peyer's patches.

111 ion cascade that dictates the specificity of lymphocyte homing to PLNs.

112 During lymphocyte homing to secondary lymphoid organs and insta

113 ectin expressed on leukocytes is involved in lymphocyte homing to secondary lymphoid organs and leuko

114 kocyte adhesion molecule L-selectin mediates lymphocyte homing to secondary lymphoid organs and to ce

115 ment into the inflamed peritoneal cavity and lymphocyte homing to secondary lymphoid organs were impa

116 During the process of lymphocyte homing to secondary lymphoid organs, such as

117 d VLA-4-mediated adhesion as well as human T lymphocyte homing to secondary lymphoid organs.

118 by which fever-range temperatures stimulate lymphocyte homing to secondary lymphoid tissues by incre

119 The role of various adhesion molecules in lymphocyte homing to the brain and in inflammatory autoi

120 These results indicate that T lymphocyte homing to the genital mucosa requires the int

121 alpha 4 beta 7 and L-selectin involvement in lymphocyte homing to the gut and to peripheral lymph nod

122 cell adhesion molecule-1 (MAdCAM-1) directs lymphocyte homing to the gut, and alpha E beta 7 mediate

123 ion to Peyer's patch venules, but suppressed lymphocyte homing to the gut, diminishing the capacity o

124 ability, reduced mucosal injury, and reduced lymphocyte homing to the gut.

125 olecule (MAdCAM-1) plays a pivotal role in T-lymphocyte homing to the gut.

126 molecule-1 (MAdCAM-1) to selectively reduce lymphocyte homing to the intestinal tract.

127 receptors may be particularly important for lymphocyte homing to the RA joint.

128 According to the current paradigm, lymphocyte homing to the small intestine requires the ex

129 (ultraviolet-induced vitamin D3) to imprint lymphocyte homing to the small intestines and T cell mig

130 mune system may be compartmentalized because lymphocyte homing to the upper respiratory tract appears

131 The steps involved in lymphocyte homing to the white pulp cords of the spleen

132 ndothelial surfaces have been identified for lymphocyte homing to various lymphoid organs and to tiss

133 the requirement of CRAC channel function for lymphocyte homing using expression of a dominant-negativ

134 Human and mouse lymphocyte homing was assessed, and cells were tracked w

135 Lymphocyte homing, which contributes to inflammation, ha

136 Mutant mice maintained robust lymphocyte homing, yet they lacked O-glycan L-selectin l