ライフサイエンスコーパス: lymphocyte subset

1 ontinuous activation/proliferation of this T-lymphocyte subset.

2 pulation, particularly within the CD8+ CD57+ lymphocyte subset.

3 cytic infections that are controlled by this lymphocyte subset.

4 NHL does not cause prolonged suppression of lymphocyte subsets.

5 trating CD4 and CD8 lymphocytes and CXCR3+ T-lymphocyte subsets.

6 cytotoxicity and to enumerate and phenotype lymphocyte subsets.

7 n, but with different kinetics, in different lymphocyte subsets.

8 f pro- and anti-inflammatory cytokines and T-lymphocyte subsets.

9 s of trafficking and proliferation for these lymphocyte subsets.

10 cantly higher frequencies than on peripheral lymphocyte subsets.

11 tion and hyperactivation of specific splenic lymphocyte subsets.

12 load and had no effect on CD4(+)- or CD8(+)-lymphocyte subsets.

13 tissue architecture and the distribution of lymphocyte subsets.

14 cs of innate leukocytes and naive and memory lymphocyte subsets.

15 ndothelial cells, myeloid cells, and certain lymphocyte subsets.

16 C attracts eosinophils in addition to memory lymphocyte subsets.

17 d in CD4(+), CD8(+), CD20(+), and CD16/56(+) lymphocyte subsets.

18 ir expression is differentially regulated in lymphocyte subsets.

19 els of this receptor in different functional lymphocyte subsets.

20 ns include immunophenotyping of alloreactive lymphocyte subsets.

21 localized predominately in CD4(+) and CD8(+) lymphocyte subsets.

22 and blood was drawn to test for viruses and lymphocyte subsets.

23 ells, indicating an efficient priming of all lymphocyte subsets.

24 that share the ability to activate specific lymphocyte subsets.

25 vitamin A on birth outcomes and counts of T lymphocyte subsets.

26 kine-release syndrome and no impact on blood lymphocyte subsets.

27 sitive EBV serologies. and markedly abnormal lymphocyte subsets.

28 rallel activation-dependent arrest of homing lymphocyte subsets.

29 tors expressed on natural killer cells and T lymphocyte subsets.

30 robust generation of functionally diverse T lymphocyte subsets.

31 o be pivotal in shaping the programs of both lymphocyte subsets.

32 ry to detect DOCK8 protein expression within lymphocyte subsets.

33 ates immune homeostasis and the fate of many lymphocyte subsets.

34 -stimulated genes, natural killer cells, and lymphocyte subsets.

35 phils, inflammatory monocytes, and different lymphocyte subsets.

36 SOCE and defects in the function of several lymphocyte subsets.

37 s involved in the homing of pDCs and certain lymphocyte subsets.

38 ase was significant for several intrahepatic lymphocytes subsets.

39 unologic response to therapy, as measured by lymphocyte subsets, 3-color flow cytometric measures, an

40 and other innate immune cells are important lymphocyte subsets able both to produce cytokines includ

41 clusion, we show that SCARF-1 contributes to lymphocyte subset adhesion to primary human HSEC and cou

42 ns, NK cells compose the third most abundant lymphocyte subset after T cells and B cells.

43 lions diagnosed with LLV infection displayed lymphocyte subset alterations and progressive behavioral

44 As compared to unrelated healthy controls, lymphocyte subset alterations were greatest in the proba

45 The association of neuropathy and lymphocyte subset alterations with chronic LLV infection

46 We compared T lymphocyte subsets among HIV-HHV-8+ and HIV-HHV-8- infec

47 Tabulated data from T- and B-lymphocyte subset analysis and antidrug antibody respons

48 Lymphocyte subset analysis demonstrated that HIV-positiv

49 Lymphocyte subset analysis performed in 20 patients avai

50 ines and their receptors; (4) expansion of B lymphocyte subset and myosin heavy chain class II-expres

51 luster of differentiation (CD)8alpha/beta+ T lymphocyte subset and the percentage of CD8alpha/beta+ T

52 f rat IL-10 (rIL-10) to assess its impact on lymphocyte subsets and activation of hepatic stellate ce

53 lar integrity and function, we evaluated how lymphocyte subsets and complement specifically affect mi

54 We determined the requirement for selected lymphocyte subsets and cytokines in the pathogenesis of

55 uation, whole blood flow cytometry to assess lymphocyte subsets and eosinophil activation, and serum

56 mined using immunohistochemical staining for lymphocyte subsets and for the cytokines interleukin-10

57 n were associated with maintenance of normal lymphocyte subsets and intact lymphoid architecture (n =

58 d immunological parameters included standard lymphocyte subsets and lymphocyte surface markers of mat

59 on allows the detection of discrete CD8(+) T lymphocyte subsets and may be useful for assessing the i

60 In addition, we generated information on lymphocyte subsets and mitogen-mediated proliferation of

61 ophil activation and induction of regulatory lymphocyte subsets and of blocking antibodies have been

62 Their lymphocyte subsets and plasma HIV viral loads were measu

63 ly viremia are mediated by multiple effector lymphocyte subsets and serum antibodies.

64 d numbers of human CD4(+) naive and memory T lymphocyte subsets and skin- and gut-homing memory T cel

65 ant expression of granzymes A and B in human lymphocyte subsets and T regulatory cells, which suggest

66 s remitter) to determine absolute numbers of lymphocyte subsets and the proportion of glycosylphospha

67 may involve antagonism between T helper (TH) lymphocyte subsets and their cytokines.

68 t of A-T and age on the proportions of major lymphocyte subsets and their pattern of CD95 expression

69 ssion, such as markers of epithelial injury, lymphocyte subsets, and circulating fibrocytes, will be

70 r lung leukocytes, including eosinophils and lymphocyte subsets, and depletion of neutrophils in sens

71 Plasma interleukin (IL)-6, lymphocyte subsets, and DNA binding of nuclear factor (N

72 mCD40-LMP1tg mice had normal lymphocyte subsets, and immunization elicited an antibod

73 ments, Clinically, we assessed EBV serology, lymphocyte subsets, and the efficacy of interferon-alpha

74 tokine stimulation in human memory and naive lymphocyte subsets as identified by five differentiation

75 ed increase in the total number of activated lymphocyte subsets as indicated by CD69 upregulation.

76 In parallel, T lymphocyte subsets, as key constituents of the adaptive

77 terations in the receptor populations within lymphocyte subsets, as well as in repertoires responding

78 with monoclonal antibodies that deplete each lymphocyte subset at the time of virus inoculation.

79 (+), central memory CD4(+), and regulatory T-lymphocyte subsets at enrollment was not associated with

80 The evolutionary conservation of T lymphocyte subsets bearing alphabeta TCRs using invarian

81 irmed by antibody-mediated depletion of this lymphocyte subset before a third infection.

82 to reduced fibrosis and alterations in liver lymphocyte subsets both in untreated liver and following

83 CD1-deficient mice were found to lack this lymphocyte subset, but they could nevertheless mount a p

84 l marker for discriminating normal B lineage lymphocyte subsets, but our results suggest new ways for

85 e performed comprehensive phenotyping of 120 lymphocyte subsets by high dimensional flow cytometry, a

86 Mean lymphocyte subset (CD4+/CD8+) ratios were significantly

87 data describing the effect of alemtuzumab on lymphocyte subsets collected during the phase 3 trial pr

88 In this review, we summarize the main lymphocyte subsets controlling immune responsiveness in

89 sion, blood stem cell recipients have higher lymphocyte-subset counts and this appears to result in f

90 Immune variables included lymphocyte subsets, cytokine production, and markers of

91 Examination of lymphocyte subsets demonstrated that phenotypically naiv

92 mplete protection, and transfers of purified lymphocyte subsets demonstrated that this effect require

93 In vivo lymphocyte subset depletions established that both T- an

94 ively demonstrate that the predominance of a lymphocyte subset determines the functional consequences

95 w-derived or parenchymal cells for mediating lymphocyte subset development.

96 Plasma viral load, lymphocyte subsets, diagnostic evaluation (including cul

97 We investigated whether CD4 and CD8 lymphocyte subsets differed in IL-7Ralpha expression and

98 ce markers could be used directly to monitor lymphocyte subset distribution in human diseases.

99 h of the remaining IL-5- or IL-17A-producing lymphocyte subsets dominated the neutrophil or eosinophi

100 reg population increased more than any other lymphocyte subset during HD IL-2 therapy and had an acti

101 y a unique dual role of attracting activated lymphocyte subsets during inflammation as well as facili

102 T cells were the predominant lymphocyte subset entering PLN, MLN, Peyer's patches, an

103 ined that proliferating cells, regardless of lymphocyte subset, exhibited increased expression of CD2

104 lls affecting both memory and naive CD4(+) T lymphocyte subsets following administration by either ro

105 ut mice revealed a requirement for the CD4 T lymphocyte subset for the complete rejection of tumors.

106 mal patterns of SH2D1A protein expression in lymphocyte subsets for healthy subjects.

107 revealed a requirement for both CD4 and CD8 lymphocyte subsets for SLC-mediated tumor regression.

108 TS were assessed for immunologic conditions, lymphocyte subsets, forkhead box P3 (FOXP3)(+) Treg cell

109 theta), a key signaling molecule in multiple lymphocyte subsets, formed microclusters in activated NK

110 We measured lymphocyte subset frequency and memory T-cell gamma inte

111 rmine F-ara-A-induced apoptosis in different lymphocyte subsets from CLL patients and normal controls

112 characteristics of B, CD4(+) T and CD8(+) T-lymphocyte subsets from monozygotic twins, we quantify t

113 telomerase activity are impaired in primary lymphocyte subsets from patients with CHH.

114 a), and expression of GCR were determined in lymphocytes subsets from cultured blood using flow cytom

115 ha) and expression of GCR were determined in lymphocytes subsets from cultured blood using flow cytom

116 CMV defense, revealing that these two innate lymphocyte subsets function together to fine-tune antivi

117 file of cord and adult blood lymphocytes and lymphocyte subsets has been assessed at the single-cell

118 Therefore, cytotoxic lymphocyte subsets have similar requirements for Munc13-

119 on, JSY3 provirus was found only in the CD4+ lymphocyte subset; however, by 14 weeks p.i., the greate

120 mune reconstitution included measurements of lymphocyte subsets, immunoglobulins, and response to vac

121 random to evaluate the distribution of BALT lymphocyte subsets immunohistochemically.

122 costimulatory molecule CD161 is expressed on lymphocyte subsets implicated in promoting respiratory i

123 Among the various lymphocyte subsets implicated in protection against canc

124 To determine the relative contribution of lymphocyte subsets important for recovery from infection

125 adhesion of memory T cells, the predominant lymphocyte subset in atherosclerotic plaque.

126 s expressing the Vdelta3 TCR make up a minor lymphocyte subset in blood but are enriched in liver and

127 NK cells are a principal tissue-infiltrating lymphocyte subset in patients with OA and patients with

128 the presence of a novel memIgD(+)memIgM(-) B lymphocyte subset in trout that expresses memCCR7 and re

129 unction tests were performed including blood lymphocyte subsets in a random subgroup.

130 e previously observed alterations in splenic lymphocyte subsets in animals with defective migration o

131 ntent and WBC composition changes, including lymphocyte subsets in blood and bone marrow, showed diff

132 ministration markedly altered homeostasis of lymphocyte subsets in blood, with NK cells and gammadelt

133 ing culture was examined independently with lymphocyte subsets in fresh blood, apoptosis was negativ

134 f the ovulatory cycle on HIV-1 RNA level and lymphocyte subsets in HIV-infected women, blood specimen

135 The composition of lymphocyte subsets in hormone-induced lactation breast m

136 Studies on the role of lymphocyte subsets in human diseases have been hampered

137 sed to characterize functional activity of T-lymphocyte subsets in humans infected with T. gondii.

138 the point of rescuing the deficiency of such lymphocyte subsets in IL-15Ralpha(-/-) mice.

139 epresent the first analysis of the role of T lymphocyte subsets in immunity to spotted fever group ri

140 use in therapeutic manipulation of selective lymphocyte subsets in immunological disorders.

141 is, we evaluated circulating IL-7 levels and lymphocyte subsets in multiple clinical cohorts with T-c

142 ceptors and an activation marker on multiple lymphocyte subsets in paired liver biopsy and peripheral

143 ixed hematopoietic chimerism and recovery of lymphocyte subsets in patients receiving a modified CKBM

144 lusion, apoptosis occurs in a broad range of lymphocyte subsets in patients with sepsis and correlate

145 Lymphocyte subsets in peripheral blood, thymus, and sple

146 The role of T-lymphocyte subsets in recovery from foot-and-mouth disea

147 The importance of T-lymphocyte subsets in the control of poxvirus infections

148 To increase our understanding of the role of lymphocyte subsets in the establishment of viral latency

149 iency, characterized by persistently low CD4 lymphocyte subsets in the peripheral blood.

150 We decided to evaluate the role of T lymphocyte subsets in tumor immunity induced by recombin

151 assessed the relative distribution of total lymphocyte subsets in untreated versus anti-LFA-1-treate

152 y reflect its ability to stimulate different lymphocyte subsets in vivo through the activities of rec

153 was associated with increases in circulating lymphocyte subsets including PD-L1E-bearing lymphocytes,

154 because of (a) reduction in CCR5 and CXCR3 T-lymphocyte subset infiltration into the graft, (b) atten

155 efine this population as a distinct memory T-lymphocyte subset, intermediate between naive and centra

156 rthritis is the segregation of CD4 and CD8 T lymphocyte subsets into distinct microdomains within the

157 Migration of lymphocyte subsets into these compartments is essential

158 However, the T-lymphocyte subsets involved in the pathophysiology of hy

159 resentation, processing, immune recognition, lymphocyte subsets involved, and mechanism of cell death

160 Cooperation between these lymphocyte subsets involves recognition of antigens co-p

161 Determination of T-lymphocyte subsets is a simple and effective parameter t

162 ducing Th17 cells, but its function in other lymphocyte subsets is not well understood.

163 Transfer of specific T lymphocyte subsets isolated from the spleens of healthy

164 om B6.C-H2bm12 mice were transplanted into T lymphocyte subset knockout recipients and T lymphocyte-r

165 expression levels of L-selectin in different lymphocyte subsets, L-selectin-mediated enhancement of c

166 piratory tract, with the depletion of either lymphocyte subset leading to increased titers in the lun

167 In all patients analyzed for lymphocyte subsets, lymphopenia induced by TMZ affected

168 Treatments that increase GCR in these lymphocyte subsets may improve graft survival.

169 Treatments that increase GCR in these lymphocyte subsets may improve graft survival.

170 Blood was obtained for enumeration of lymphocyte subsets, measurement of serum autoantibody an

171 ost a complete absence of CD4 T lymphocytes, lymphocyte subset monitoring is useful in identifying de

172 induced expansion of circulating leukocytes, lymphocyte subsets, monocytes and granulocytes.

173 T lymphocyte subsets, monocytes and neutrophils from organ

174 ts peaked around 1 year, whereas most memory lymphocyte subsets more gradually increased during the f

175 t changes in the numbers and distribution of lymphocyte subsets, NK cell receptor expression, or in v

176 rols the differentiation and function of a T lymphocyte subset, NK1+ natural T cells, proposed to reg

177 nd their plasma viral RNA loads, circulating lymphocyte subset numbers, and eventual disease outcomes

178 lso was determined for CD4- and CD8-enriched lymphocyte subsets obtained by antibody and complement d

179 ive, unactivated CD26(low) CD45RA+ CD45R0- T lymphocyte subset of peripheral blood lymphocytes.

180 Ly-6C Ag were examined on splenic and thymic lymphocyte subsets of Ly-6.1 and Ly-6.2 strains of mice

181 signals for HHV-8 were demonstrated in the B lymphocyte subsets of PBMCs and/or in spermatozoa and mo

182 No modification of memory T lymphocytes subsets or numbers was observed in the perip

183 ll activation, significant alteration of the lymphocyte subsets, or induce clinically observable auto

184 luences of these core cytokines on precursor lymphocyte subsets overlap during development and are of

185 Groups were compared with respect to lymphocyte subsets, phagocytosis, oxidative burst capaci

186 Adoptive transfer of T lymphocyte subset populations into nude recipients confi

187 in five HIV-negative patients showed similar lymphocyte subset profiles as BAL, indicating that BAL r

188 Circulating T-lymphocyte subset profiles in conventional HIV- BDD were

189 Both CD4 and CD8 lymphocyte subsets proliferated to pathogenic peptides.

190 )CD28(null) T cells, a functionally aberrant lymphocyte subset rarely seen in individuals younger tha

191 l transplantation because they are the first lymphocyte subset recovering after the allograft.

192 may allow differential, segmental control of lymphocyte subset recruitment into functionally distinct

193 usly shown that gammadeltaT cells, a small T lymphocyte subset, reduce acute inflammatory lung damage

194 PG27 largely normalized splenic T lymphocyte subsets, reduced allospecific cytotoxic T lym

195 Lymphocyte subsets remained unaltered in all monkeys.

196 the DNA methylome and the transcriptome of B-lymphocyte subsets representing stages of the humoral im

197 we review newly discovered roles for BCL6 in lymphocyte subsets residing within and outside of germin

198 Flow cytometric analyses of T lymphocyte subsets revealed that the proportions of Fcep

199 The identification of the lymphocyte subsets secreting interferon (IFN) gamma and

200 , in vivo depletion of either CD4+ or CD8+ T lymphocyte subsets significantly prolonged survival in m

201 er, recent studies have revealed two lamprey lymphocyte subsets so closely resembling B cells and T c

202 These specialized tissue-resident lymphocyte subsets span the innate-adaptive continuum an

203 Whether L-selectin also regulates lymphocyte subset-specific migration into specific lymph

204 ells function via provision of help to other lymphocyte subsets, such as B cells and CD8 T cells, or

205 ted role in facilitating activation of other lymphocyte subsets, such as invariant natural killer T (

206 l differences in CD44 function between these lymphocyte subsets suggest an important biological role

207 Recently, the T lymphocyte subset T(H)17 was shown to play a role in reg

208 increases in the frequency of CD4 and CD8 T lymphocyte subsets, T cell activation markers CXCR3, CD6

209 We compare changes in lymphocyte subsets, T cell proliferative responses to di

210 show that NFATx mRNA was expressed in all T lymphocyte subsets tested and was highest in CD4+CD8+ do

211 onocyte), consistent with a progenitor/pre-B lymphocyte subset that does not express cytoplasmic mu-c

212 ts for a possible role for CD8(+) T cells, a lymphocyte subset that has long been underrated in multi

213 emonstrate that CD4+ T cells are the primary lymphocyte subset that mediates cellular infiltration, l

214 marginal zone (MZ) B cells, a pre-activated lymphocyte subset that mounts antibody responses to T-ce

215 ing; however, the mechanism of death and the lymphocyte subsets that are targeted remain unknown.

216 ggest that fetal thymi contain several novel lymphocyte subsets that can be induced to overgrow the n

217 in signaling pathways were seen in all SLE B lymphocyte subsets that manifested phenotypic features o

218 , and to shed light on the specialization of lymphocyte subsets that mediate inflammation and immune

219 vances in the understanding of the diverse T lymphocyte subsets that provide acute and long-term prot

220 aining was significantly reduced on CD8(+) T lymphocyte subsets that showed immunophenotypic evidence

221 his study, we used a murine model to examine lymphocyte subsets that ultimately drive the eosinophil

222 fectivity assays, using live sorted CD4(+) T lymphocyte subsets, that 30-90% of circulating naive cel

223 ow that the ObR is expressed on normal mouse lymphocyte subsets, that leptin plays a role in lymphocy

224 Normal animals contain an autoreactive B lymphocyte subset, the B-1 subset, which is controlled b

225 seropositivity modulated the distribution of lymphocyte subsets, the functional defects were present

226 Although statistically significant for both lymphocyte subsets, this relationship was more pronounce

227 eptors and their ligands in the migration of lymphocyte subsets through lymphoid and nonlymphoid tiss

228 integrin/VCAM-1, and LFA-1, targets specific lymphocyte subsets to BALT.

229 The precise role and contributions of T lymphocyte subsets to CAV development remains unknown.

230 ytes, granulocytes, lymphocytes, and several lymphocyte subsets to confirm the diagnosis of DC, disti

231 gy, we evaluated the regional recruitment of lymphocyte subsets to different areas of the female geni

232 investigate the ability of distinct CD4(+) T lymphocyte subsets to enter and persist in non-lymphoid,

233 e so as to dissect the contribution of these lymphocyte subsets to HLH-like disease severity after ly

234 The relative contributions of T-lymphocyte subsets to host defense in cattle infected wi

235 ities correlate with functional migration of lymphocyte subsets to known CCR7 ligands.

236 Thus, the differential migration of T and B lymphocyte subsets to lymphoid tissues is regulated in p

237 d us to investigate the ability of different lymphocyte subsets to produce this dichotomous eosinophi

238 isperses the immunologic repertoire, directs lymphocyte subsets to the specialized microenvironments

239 there were no differences in the profiles of lymphocyte subsets [total T cells (CD3+), T helper cells

240 Thus, chemokines can regulate the arrest of lymphocyte subsets under flowing conditions, which may a

241 ontained a higher percentage of Tregs in the lymphocyte subset versus regressor tumors.

242 We evaluated mucosal T lymphocyte subsets, virus-specific cellular responses, g

243 However, when either lymphocyte subset was donated by the aged mice, the muta

244 cytometric techniques we found that the CD4 lymphocyte subset was preferentially recruited to the up

245 amma, TNFalpha, and a loss of GCR from these lymphocyte subsets was also found in BOS.

246 gamma, TNFalpha and a loss of GCR from these lymphocyte subsets was also found in BOS.

247 Also, infection of both CD4(+) and CD8(+) lymphocyte subsets was associated with higher virus load

248 cytometry and expression profiling of sorted lymphocyte subsets, we unequivocally demonstrate the exi

249 eived placebo in terms of sequential data on lymphocyte subsets; weight, height, and head circumferen

250 Lymphocyte subsets were abnormal in all patients; the mo

251 Peripheral blood lymphocyte subsets were analyzed by flow cytometry.

252 Multilineage chimerism, clonal deletion, and lymphocyte subsets were analyzed by flow cytometry.

253 Humoral immune responses and CD4+ lymphocyte subsets were compared in 5 HIV-uninfected vac

254 depletion indicated that both CD4+ and CD8+ lymphocyte subsets were decreased.

255 d by enzyme-linked immunosorbent assay kits, lymphocyte subsets were determined using four-color fluo

256 Lymphocyte subsets were enumerated by flow cytometry.

257 Concurrent BALF lymphocyte subsets were examined by flow cytometry, incl

258 nd 365 after transplantation, counts of most lymphocyte subsets were higher in the blood stem cell re

259 To address which lymphocyte subsets were impaired in the LTalpha-/- mice,

260 rmine if distinct alphabeta and gammadelta T-lymphocyte subsets were involved in the response of the

261 No obvious differences in lymphocyte subsets were observed.

262 determine the source of IL-10, CD4+ and CD8+ lymphocyte subsets were obtained by selective depletion

263 The three T-lymphocyte subsets were positively correlated with CD4 T

264 eta(+) gammadelta T cells constitute a novel lymphocyte subset, which is strongly enriched within the

265 Thymic NK1.1+ cells are a recently described lymphocyte subset whose biologic function is not well de

266 Natural killer (NK) T cells are a lymphocyte subset with a distinct surface phenotype, an

267 role during the development of NKT cells, a lymphocyte subset with immunoregulatory functions in res

268 Type I NKT cells are a lymphocyte subset with important roles in regulating imm

269 T(SCM) constitute a recently identified lymphocyte subset with stem cell-like qualities, includi

270 other measures of blood tumor burden, i.e., lymphocyte subsets with a CD4+CD7- and CD4+CD26- phenoty

271 or identification of peripheral blood memory lymphocyte subsets with distinct tissue and microenviron

272 it large numbers of naive T cells and harbor lymphocyte subsets with opposing activities, including C

273 ene expression profiles and peripheral blood lymphocyte subsets with those of subjects with stable gr

274 lymphoid cells encompass a diverse array of lymphocyte subsets with unique phenotype that initiate i

275 We analyzed the kinetics of T-lymphocyte subsets within the first 8 months posttranspl