ライフサイエンスコーパス: lymphohematopoietic

1 of the genotypic reversion, we examined each lymphohematopoietic and stromal cell lineage in an FA pa

2 etween alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agr

3 mong spouses, relative SMRs exceeded 1.0 for lymphohematopoietic cancers and malignancies of the dige

4 ficant increasing trend for incidence of all lymphohematopoietic cancers associated with lifetime exp

5 he relative mortality ratio was elevated for lymphohematopoietic cancers, melanoma, and digestive sys

6 Using bone marrow chimeras, we show that lymphohematopoietic cell lineages largely dictate the pr

7 oposide-induced antiproliferative effects in lymphohematopoietic cell lines and acute myelogenous leu

8 show that up to 80% of BAK (but not BAX) in lymphohematopoietic cell lines is oligomerized and bound

9 hematopoietic stem cells and in a variety of lymphohematopoietic cell lines.

10 It is unknown if other lymphohematopoietic cell populations can be used as a DS

11 he development of multiple lineages of human lymphohematopoietic cells and formation of secondary lym

12 s that give rise to these yolk sac primitive lymphohematopoietic cells and the molecular events contr

13 t mouse embryonic stem (ES) cells to various lymphohematopoietic cells is an in vitro model of the he

14 ggest that TGF-beta1 overexpression by donor lymphohematopoietic cells may enhance tolerance inductio

15 fold-higher level of ADA expression in human lymphohematopoietic cells than the PA317/LASN vector cur

16 Thus, dendritic cells and macrophages clear lymphohematopoietic cells that have downregulated CD47 d

17 This resistance is mediated by lymphohematopoietic cells transplanted with the graft, s

18 immunizations of the donor strains with host lymphohematopoietic cells were used.

19 a critical indicator for determining whether lymphohematopoietic cells will survive or be cleared.

20 in the clearance of virtually all CD47(-/-) lymphohematopoietic cells within 1 day after infusion.

21 liminate both normal and malignant host-type lymphohematopoietic cells without causing injury to nonl

22 ad the unique capacity to eliminate the host lymphohematopoietic cells without nonlymphohematopoietic

23 pulation with a comprehensive array of human lymphohematopoietic cells, including T cells, B cells, a

24 but also both primitive and definitive human lymphohematopoietic cells.

25 ailed to eliminate malignant and normal host lymphohematopoietic cells.

26 iferation, differentiation, and apoptosis in lymphohematopoietic cells.

27 Multilineage lymphohematopoietic chimerism (5%-80% donor CD3+ or CD3-

28 report of the deliberate induction of mixed lymphohematopoietic chimerism after a nonmyeloablative p

29 Mixed lymphohematopoietic chimerism can provide an effective m

30 a with end-stage renal disease through mixed lymphohematopoietic chimerism has been achieved, as evid

31 viously demonstrated that induction of mixed lymphohematopoietic chimerism resulted in donor specific

32 eparative therapy for the induction of mixed lymphohematopoietic chimerism, we treated a 55-year-old

33 allotolerance through the induction of mixed lymphohematopoietic chimerism.

34 w transplantation and the induction of mixed lymphohematopoietic chimerism.

35 host disease, and the establishment of mixed lymphohematopoietic chimerism.

36 oth recipients also exhibited GvH-associated lymphohematopoietic compartment (LHC) alterations as evi

37 demonstrated that a signaling event in a non-lymphohematopoietic compartment of the lung prevented th

38 specifically at the stem/progenitor stage of lymphohematopoietic development that appears to regulate

39 the inhibition of GVHD lethality and delayed lymphohematopoietic effects of the combined MoAb regimen

40 immunosuppress the recipient to permit donor lymphohematopoietic engraftment and thereby establish a

41 Nine patients had long-term, stable donor lymphohematopoietic engraftment at levels that sufficed

42 nonreactive siblings, have maintained stable lymphohematopoietic engraftment with donor cells for gre

43 or are being used for the reconstitution of lymphohematopoietic function after myeloablative, near-m

44 r lymphocyte infusions (DLIs) manifesting as lymphohematopoietic graft-versus-host (LH-GVH) and graft

45 given to stable mixed chimeras resulting in lymphohematopoietic graft-versus-host (LH-GVH) response.

46 llo-HCT recipients is due to augmentation of lymphohematopoietic graft-versus-host reaction (LGVHR) a

47 experiments show that reconstitution of all lymphohematopoietic lineages across the entire MHC trans

48 s, including the progenitor cells of all the lymphohematopoietic lineages and lymphohematopoietic ste

49 Patients with a lymphohematopoietic malignancy considered to be at high

50 Chimerism in the peripheral blood and lymphohematopoietic organs was assessed by flow cytometr

51 rum analyses on infected ferrets to identify lymphohematopoietic parameters associated with mild to s

52 During mouse development, the first lymphohematopoietic precursor cells and myeloid or eryth

53 There they generate primitive lymphohematopoietic precursor cells and the first erythr

54 ent stem cells showed a reduced expansion of lymphohematopoietic progenitor cells and defects of thym

55 CD7+CD34+ lymphohematopoietic progenitor cells in bone marrow are

56 tuted with SYK-deficient fetal liver-derived lymphohematopoietic progenitor cells show a block in B-c

57 abrogates the lymphoid potentials of murine lymphohematopoietic progenitors and the reconstituting a

58 We isolated the earliest lymphohematopoietic progenitors by using embryonic stem

59 First, we tested the effects of IL-3 on lymphohematopoietic progenitors by using lineage-negativ

60 e gene defect at the level of the autologous lymphohematopoietic progenitors could therefore represen

61 urface marker that can identify the earliest lymphohematopoietic progenitors in mouse development.

62 proposed to be related to either defects in lymphohematopoietic progenitors or the thymic microenvir

63 However, the earliest lymphohematopoietic progenitors that appear during mouse

64 Multipotent lymphohematopoietic progenitors were generated later as

65 evated the CD34(+) cell population though no lymphohematopoietic progenitors were induced.

66 r mixed NK cell colony formation from single lymphohematopoietic progenitors.

67 Remarkably, antihost lymphohematopoietic reactions, including GVL effects aga

68 ernative donor sources can provide effective lymphohematopoietic reconstitution, but time to engraftm

69 m the same donor achieves multilineage human lymphohematopoietic reconstitution, including dendritic

70 MoAb infusion resulted in impaired lymphohematopoietic recovery in congenic BMT recipients

71 transplanted single SP cells are capable of lymphohematopoietic repopulation at near absolute effici

72 ly because of back mutation, originated in a lymphohematopoietic stem cell and not solely in a lympho

73 iability suggest that mutations arise in the lymphohematopoietic stem cell compartment and that these

74 The availability of lymphohematopoietic stem cell lines should facilitate th

75 ate the spontaneous genotypic reversion in a lymphohematopoietic stem cell.

76 The site of origin of lymphohematopoietic stem cells (HSC) that initiate defin

77 The classical definition of lymphohematopoietic stem cells (LHSC), the most primitiv

78 of all the lymphohematopoietic lineages and lymphohematopoietic stem cells (stem cells).

79 ntial therapeutic approaches by manipulating lymphohematopoietic stem-progenitor cells to express Fas

80 roper and they were able to reconstitute the lymphohematopoietic system of irradiated mice.

81 -versus-host (GVH) reactions confined to the lymphohematopoietic system without inducing graft-versus

82 ficial alloresponse to take place within the lymphohematopoietic system, leading to graft-versus-lymp

83 mias and lymphomas reside largely within the lymphohematopoietic system, we have proposed that the de

84 tients with life-threatening diseases of the lymphohematopoietic system.

85 ectively in adult tissues and in cell of the lymphohematopoietic system.

86 -/-) mice had normal cellular composition in lymphohematopoietic tissues, but T-bet(-/-) lymphocytes

87 r cell chimerism in the peripheral blood and lymphohematopoietic tissues.

88 fining of the donor CD8+ T-cell expansion to lymphohematopoietic tissues.

89 ice were transplanted with porcine and human lymphohematopoietic tissues.

90 of the graft-versus-host alloresponse to the lymphohematopoietic tissues.

91 trated expression of the SLA DR transgene in lymphohematopoietic tissues.

92 phology in the thymus, and with chimerism in lymphohematopoietic tissues.

93 genitor transplantation to effectively treat lymphohematopoietic tumors and reduce early toxicity.