ライフサイエンスコーパス: lymphotactin

1 n the C-terminal region of the protein human lymphotactin.

2 be essential for the biological activity of lymphotactin.

3 We recently identified XCL1/lymphotactin, a chemokine primarily produced by CD8(+) T

4 XCL1/lymphotactin, a unique metamorphic chemokine, was recent

5 The results revealed that human lymphotactin adopts the conserved chemokine fold, which

6 s of M3 in complex with C chemokine ligand 1/lymphotactin and CC chemokine ligand 2/monocyte chemoatt

7 -5, IL-13, and IFN-gamma, and the chemokines lymphotactin and RANTES, in stimulated thymocyte culture

8 In contrast, Th1 cells secrete lymphotactin and RANTES, though unlike IFN-gamma, expres

9 including RANTES, IFN-inducible protein-10, lymphotactin, and IL-1R antagonist, as well as altered l

10 mokine interleukin-8, the murine C chemokine lymphotactin, and the murine CX(3)C chemokine fractalkin

11 duced in the presence of a neutralizing anti-lymphotactin antiserum and to a lesser extent by neutral

12 affinity identified two arginine residues of lymphotactin as critical for glycosaminoglycan binding.

13 -1alpha (MIP-1alpha) and -1beta (MIP-1beta), lymphotactin), b) type-2-dominant (eotaxin, monocyte che

14 , granulocyte colony-stimulating factor, and lymphotactin by live P. gingivalis, but not by P. gingiv

15 onal solution structure of recombinant human lymphotactin by NMR spectroscopy.

16 e mRNAs was increased, and low expression of lymphotactin, C10, MIP-2, and MIP-1alpha mRNAs was detec

17 ttin, human beta defensin 1, truncated human lymphotactin, Cytochrome C, holo hemoglobin-alpha, ovalb

18 MIP-1beta, MIP-1alpha, MCP-1, TCA-3) and C (lymphotactin) families.

19 he expression of the chemokine receptors for lymphotactin, fractalkine, CCR1-10, and CXCR1-5.

20 In contrast, lymphotactin gene expression increased only slightly in

21 ocyte recruitment assay, suggesting that the lymphotactin-glycosaminoglycan interactions detected in

22 We detected lymphotactin-heparin binding by NMR and mapped this inte

23 NMR spectra of human lymphotactin (hLtn), obtained under various solution con

24 ion on the structural stability of the human Lymphotactin (hLtn).

25 The presence of lymphotactin in supernatants from activated DETC 7-17 cu

26 Others (MCP-2, MCP-3, eotaxin, lymphotactin, LARC, TCA-3) displayed peak expression lat

27 Injection of lymphotactin (Lptn) into the peritoneum caused an influx

28 Lymphotactin (Lptn) is a C chemokine produced predominan

29 bcutaneous injections of a vaccine combining lymphotactin (Lptn)- and interleukin-2 (IL-2)-secreting

30 sing a recently discovered T-cell chemokine, lymphotactin (Lptn).

31 Lymphotactin (Ltn) adopts two distinct structures in equ

32 Lymphotactin (Ltn) is a unique chemokine in that it cont

33 Lymphotactin (Ltn) is a unique chemokine that under phys

34 Lymphotactin (Ltn), macrophage inflammatory protein (MIP

35 As encoding a lymphocyte-specific chemokine, lymphotactin (Ltn), were isolated from mouse pro-T cell

36 so quantified the effects of acute stress on lymphotactin- (LTN; a predominantly lymphocyte-specific

37 10-kDa interferon-inducible protein, RANTES, lymphotactin, macrophage inflammatory protein 1beta (MIP

38 K receptor induced high levels of IFN-gamma, lymphotactin, macrophage-inflammatory protein (MIP)1alph

39 cell-derived and chemokine-related cytokine/lymphotactin, macrophage-inflammatory protein 1alpha, ma

40 Eotaxin, lymphotactin, MCP-1, Mig, and SDF-1 were present in both

41 The chemokines eotaxin, IP-10, lymphotactin, MCP-1, Mig, RANTES, and SDF-1 were examine

42 were observed, and levels of RANTES, MCP-1, lymphotactin, MIP-1alpha, MIP-1beta, and MIP-2 mRNAs wer

43 synthesize several chemokines that included lymphotactin, monocyte chemoattractant protein-1 (MCP-1)

44 In contrast, lymphotactin mRNA was present in activated spleen gamma

45 TC cultures also produced copious amounts of lymphotactin mRNA.

46 ith gamma delta TCR expressed high levels of lymphotactin mRNA.

47 ta, IL-4, IL-6, TNF-alpha, and the chemokine lymphotactin, mRNAs for IL-1beta, TNF-alpha, and lymphot

48 ain at least some regions of disorder (human lymphotactin, N-terminal p53, alpha-Synuclein, N-termina

49 Second, allografts demonstrated sustained lymphotactin, RANTES, and IP-10 expression, beginning at

50 TNF-alpha and IFN-gamma mRNA and chemokines lymphotactin, RANTES, and macrophage inflammatory protei

51 the C-terminal extension, which is unique to lymphotactin, remains to be elucidated.

52 -2), and CXCL10 (inducing protein-10), XCL1 (lymphotactin/single C motif-1alpha/activation-induced, T

53 Lymphotactin, the sole identified member of the C class

54 Lymphotactin, the unique member of the "C" chemokine sub

55 ults demonstrate that like other chemokines, lymphotactin utilizes highly specific glycosaminoglycan-

56 otein (MIP)-1 alpha, MIP-1 beta, RANTES, and lymphotactin was inducible in DETC 7-17 cells, whereas m

57 itions used for the structure determination, lymphotactin was predominantly monomeric; however, pulse

58 Strikingly, lymphotactin was the most abundant chemokine produced by

59 hotactin, mRNAs for IL-1beta, TNF-alpha, and lymphotactin were down-modulated in the presence of alph

60 luding chemokines such as MIP-1beta (CCL-4), lymphotactin (XCL-1), IFN-gamma-inducible protein 10 (IP

61 crophage colony-stimulating factor (GM-CSF); lymphotactin (XCL1); tumor necrosis factor receptor supe