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1 hatidylethanolamine, phosphatidylserine, and lysophosphatidylcholine.
2 mulate within phospholipid fractions such as lysophosphatidylcholine.
3 te lower levels of the "come-get-me" signal, lysophosphatidylcholine.
4 on the production of its catalytic product, lysophosphatidylcholine.
5 ighly selective generation of 2-arachidonoyl lysophosphatidylcholine.
6 ing in the production of a neutral lipid and lysophosphatidylcholine.
7 at McaP cleaves both phosphatidylcholine and lysophosphatidylcholine.
8 ing in the production of a neutral lipid and lysophosphatidylcholine.
9 poptosis by treatment with phosphocholine or lysophosphatidylcholine.
10 arachidonic acid, lysophosphatidic acid, and lysophosphatidylcholine.
11 pase activity toward the preferred substrate lysophosphatidylcholine.
12 Alcohol-induced hemifusion was inhibited by lysophosphatidylcholine.
13 nsion in the presence of meconium, serum, or lysophosphatidylcholine.
14 erol, free fatty acid, monoacylglycerol, and lysophosphatidylcholine.
15 (ATX), a secreted lysophospholipase D, from lysophosphatidylcholine.
16 xidized phospholipids with a high content in lysophosphatidylcholine.
17 rates are thought to be sphingomyelin and/or lysophosphatidylcholine.
18 nerates extracellular LPA from the precursor lysophosphatidylcholine.
19 was increased in lungs of mice that received lysophosphatidylcholine.
20 formation of early fusion intermediates with lysophosphatidylcholine.
21 for preparation of spectroscopically labeled lysophosphatidylcholines.
22 d extracts from D.42 plasma, or (d) purified lysophosphatidylcholines.
23 ofiling and regression analysis, we detected lysophosphatidylcholine 14:0, tryptophan, as well as pim
26 , diacyl phosphatidylcholines 36:4 and 38:4, lysophosphatidylcholine 17:0, and hydroxy-sphingomyelin
27 ntified plasma lysophosphatidylcholine 16:0, lysophosphatidylcholine 17:0, and lysophosphatidylcholin
28 line 16:0, lysophosphatidylcholine 17:0, and lysophosphatidylcholine 18:0 as significant metabolites
29 stimulated the production of 2-arachidonoyl-lysophosphatidylcholine (2-AA-LPC) from 1-palmitoyl-2-[(
31 d on 1) the temporal inhibition of fusion by lysophosphatidylcholine, 2) rapid dissociation of the HA
35 d coronary sinus for measurement of Lp-PLA2, lysophosphatidylcholine (a product of Lp-PLA2), and C-re
38 mmatory consequences have been described for lysophosphatidylcholine, a lipid product of cellular inj
39 ogical role of this system is to internalize lysophosphatidylcholine, a signalling lipid involved in
40 rophages upon exposure to apoptotic cells or lysophosphatidylcholine, a specific phospholipid that is
42 l insulin secretion and a role in generating lysophosphatidylcholine acceptors for arachidonic acid i
43 ipid reacylation by a novel Golgi-associated lysophosphatidylcholine acyltransferase (LPAT) induces t
44 es to LPS, was found to selectively activate lysophosphatidylcholine acyltransferase (LPCAT) (P < 0.0
45 PC) and sphingomyelin levels due to elevated lysophosphatidylcholine acyltransferase (LPCAT) and sphi
46 catalyzed by the reverse action of acyl-CoA:lysophosphatidylcholine acyltransferase (LPCAT) can tran
49 ), lysophospholipid acyltransferase (LPEAT), lysophosphatidylcholine acyltransferase (LPCAT), and lys
51 enzyme in the Lands' cycle is fatty acyl-CoA:lysophosphatidylcholine acyltransferase (LPCAT), which u
53 mouse enzyme with characteristics of a lung lysophosphatidylcholine acyltransferase (LPCAT1) that we
56 show that the phospholipid remodeling enzyme lysophosphatidylcholine acyltransferase 3 (Lpcat3) is a
58 es and proteins involved in LPC degradation (lysophosphatidylcholine acyltransferase [Lpcat] 1-4), ba
59 ophospholipids, and overexpression increased lysophosphatidylcholine acyltransferase activity 7-fold.
60 ivum) leaf protoplasts indicated that 30% of lysophosphatidylcholine acyltransferase activity colocal
61 n of the remodeling enzyme, LPCAT1 (acyl-CoA:lysophosphatidylcholine acyltransferase) in epithelia de
62 hift, leading to premature truncation of the lysophosphatidylcholine acyltransferase-1 (LPCAT1) prote
64 , we demonstrate that two genes encoding the lysophosphatidylcholine acyltransferases LPCAT1 and LPCA
67 duced lipid mixing was reversibly blocked by lysophosphatidylcholine and low temperature, 4 degrees C
72 high levels of amino acids but low levels of lysophosphatidylcholine and lysophosphatidylethanolamine
73 ed by agents that thin the membrane (L-alpha-lysophosphatidylcholine and octyl-beta-D-glucopyranoside
74 ities of the two pro-inflammatory mediators, lysophosphatidylcholine and oxidized nonesterified fatty
75 aflet lipid with phospholipase A2 to produce lysophosphatidylcholine and palmitate which were then re
76 inhibition of fusion by inverted cone-shaped lysophosphatidylcholine and promotion by cone-shaped ole
77 f systemin blocked both the release of (14)C-lysophosphatidylcholine and the accumulation of defense
78 de decreases both the steady-state levels of lysophosphatidylcholine and the capacity of the cell to
79 nd to phosphatidyl lipids, but did recognize lysophosphatidylcholine and the phosphorylcholine head g
80 ells in the presence of the fusion inhibitor lysophosphatidylcholine and then removed the inhibitor t
81 fer from water to self-assembled micelles of lysophosphatidylcholines and diacyl phosphatidylcholines
82 tigotes occurred to phosphatidylcholines and lysophosphatidylcholines and results indicate that the K
83 the plasma membrane, resulting in a peak of lysophosphatidylcholine, and (2) a subsequent, transient
84 nhibition in the adenosine, PG/lipoxygenase, lysophosphatidylcholine, and sphingosine-1-phosphate pat
85 support a novel transport mechanism by which lysophosphatidylcholines are "flipped" within the transp
86 yso-PE and lysophosphatidylglycerol, but not lysophosphatidylcholine, are taken up by LplT for reacyl
87 ments a V. cholerae VolA mutant in growth on lysophosphatidylcholine as the sole carbon source and in
88 lated splenic macrophages identifies several lysophosphatidylcholines as the resistance-inducing mole
89 vity and the signaling pathway through which lysophosphatidylcholine augments endothelial nitric-oxid
90 ythmogenic toxins (eg, ouabain, high Ca(2+), lysophosphatidylcholine, beta-adrenergic agonist, acylca
91 phatidylcholine, lysophosphatidylserine, and lysophosphatidylcholine but lacked appreciable acylating
93 human eosinophils degranulate in response to lysophosphatidylcholine, but not phosphatidylcholine, ly
96 l activation in human ALD (10 autopsies) and lysophosphatidylcholine (C24:0) injection into the parie
99 reperfusion caused a significant increase in lysophosphatidylcholine concentration compared with cont
100 urocortin, the ischemia-induced increase in lysophosphatidylcholine concentration was significantly
103 n reactions of a docosahexaenoate ester of 2-lysophosphatidylcholine (DHA-PC) was also demonstrated.
104 to arachidonic acid, lysophosphatidic acid, lysophosphatidylcholine, diacylglycerol, monoacylglycero
105 We also elicited SMase activity by adding lysophosphatidylcholine externally or by generating it w
108 potently releases arachidonic acid (AA) and lysophosphatidylcholine from mammalian cell membranes.
109 +/- 0.1 to 2.1 +/- 0.3 nmol/mg of protein), lysophosphatidylcholine (from 0.3 +/- 0.1 to 0.6 +/- 0.1
110 tes, respectively) significantly faster than lysophosphatidylcholine (>60 and 37.8 minutes, respectiv
112 salt-independent hydrolytic activity against lysophosphatidylcholine, having 6.5- and 2-fold higher k
113 -9-hydroxy-13-oxotridec-11-enoate ester of 2-lysophosphatidylcholine (HOT-PC) was devised to facilita
114 tributed to the lower levels of ceramide and lysophosphatidylcholine in CEL-expressing cells than in
115 TAG and the accumulation of small amounts of lysophosphatidylcholine in developing seeds revealed by
117 alpha-chloro fatty aldehydes and unsaturated lysophosphatidylcholine in human atherosclerotic lesions
118 ty, as measured by the accumulation of (14)C-lysophosphatidylcholine in leaves of tomato plants, incr
119 xins cleave the substrates sphingomyelin and lysophosphatidylcholine in mammalian tissues, releasing
120 is because of its hydrolysis of ceramide and lysophosphatidylcholine in promoting cholesterol esterif
121 hallenge altered the concentration of plasma lysophosphatidylcholines in an oil treatment-dependent m
122 r was associated with lower cord-blood total lysophosphatidylcholines in index and control children.
124 hepatocytes and Huh7 cells with palmitate or lysophosphatidylcholine increased their release of EVs,
125 isruption of paranodal myelin (by stretch or lysophosphatidylcholine) increased the stimulation-induc
127 infectivity) and the fusion-inhibitory agent lysophosphatidylcholine inhibit the formation of the >15
129 of lysophospholipids and PUFAs are such that lysophosphatidylcholine is able to modulate TRPM8 in the
130 s not support the stalk (e.g., as it is when lysophosphatidylcholine is added), hemifusion is inhibit
131 of known specificities demostrated that the lysophosphatidylcholine is generated by a PLA with speci
136 hroughput screen of ATX inhibition using the lysophosphatidylcholine-like substrate fluorogenic subst
137 n the cecum, as well as elevated atherogenic lysophosphatidylcholine (LPC 18:1) and lysophosphatidic
138 /-) HDL had a 4-fold increase in PC, whereas lysophosphatidylcholine (LPC) (125-fold), sphingomyelin
139 dministration of DHA to normal adult mice as lysophosphatidylcholine (LPC) (40 mg DHA/kg) for 30 days
140 A housekeeping role for iPLA2 in generating lysophosphatidylcholine (LPC) acceptors for arachidonic
142 s in serum palmitoyl-, stearoyl-, and oleoyl-lysophosphatidylcholine (LPC) and marked increases in ta
143 exposure in mice resulted in decreased serum lysophosphatidylcholine (LPC) and sphingomyelin levels d
145 n assay, we found that phospholipids such as lysophosphatidylcholine (LPC) can stimulate the sulfatid
147 dose-dependent manner, while treatment with lysophosphatidylcholine (LPC) enhanced the expression of
149 d the presence of monoacylglycerol (MAG) and lysophosphatidylcholine (LPC) hydrolytic activities, ind
150 actions of the cell membrane and serum lipid lysophosphatidylcholine (LPC) in atherosclerosis and sys
152 exhibited excellent remyelinating effects on lysophosphatidylcholine (LPC) induced demyelination in a
153 f asymmetrically incorporating single-tailed lysophosphatidylcholine (LPC) into a membrane bilayer us
154 mbrane merger was prevented by incorporating lysophosphatidylcholine (LPC) into cell membranes at the
155 secreted lysophospholipase D that hydrolyzes lysophosphatidylcholine (LPC) into lysophosphatidic acid
156 G2A, a G protein-coupled receptor for which lysophosphatidylcholine (LPC) is a high affinity ligand,
159 riments show that the soluble lipid mediator lysophosphatidylcholine (LPC) is released by p25 overexp
160 application of micromolar concentrations of lysophosphatidylcholine (LPC) led to an increase of the
161 a housekeeping enzyme that regulates cell 2-lysophosphatidylcholine (LPC) levels and arachidonate in
164 a housekeeping enzyme that regulates cell 2-lysophosphatidylcholine (LPC) levels, rates of arachidon
166 activity (PLA2) of Prdx6; addition of either lysophosphatidylcholine (LPC) or lysophosphatidic acid (
169 sophosphatidylglycerol (LPG) or zwitterionic lysophosphatidylcholine (LPC) stimulate aggregation, LPG
170 Mfsd2a is a newly described sodium-dependent lysophosphatidylcholine (LPC) symporter expressed at the
171 ectoenzyme that catalyzes the conversion of lysophosphatidylcholine (LPC) to lysophosphatidic acid (
172 ce chemotaxis through its ability to convert lysophosphatidylcholine (LPC) to lysophosphatidic acid (
173 ted enzyme responsible for the hydrolysis of lysophosphatidylcholine (LPC) to the bioactive lysophosp
174 he circulation is through a sodium-dependent lysophosphatidylcholine (LPC) transporter (MFSD2A), expr
177 ple tumor types, autotaxin produces LPA from lysophosphatidylcholine (LPC) via lysophospholipase D ac
179 Oxidized low density lipoprotein (OxLDL) or lysophosphatidylcholine (LPC), a major component of OxLD
181 her Lp-PLA2 and its major enzymatic product, lysophosphatidylcholine (LPC), are involved in blood-ret
182 es as opposed to vesicles containing L-alpha-lysophosphatidylcholine (LPC), as observed using atomic
183 tion was blocked by the hemifusion inhibitor lysophosphatidylcholine (LPC), but not if a complementar
184 We report here that increased production of lysophosphatidylcholine (LPC), catalyzed by the activati
185 large amounts of AA and the lysophospholipid lysophosphatidylcholine (LPC), from membrane preparation
186 ed were albumin, hemoglobin, C16:0 and C18:1 lysophosphatidylcholine (LPC), oleic acid (OA), palmitol
187 adherent HA-cell at different time points by lysophosphatidylcholine (LPC), so that only the cell pai
189 idermal keratinocytes and we have shown that lysophosphatidylcholine (LPC), the main lysophospholipid
191 the selective accumulation of 2-arachidonoyl lysophosphatidylcholine (LPC), which was not metabolized
192 v administration, although more radiolabeled lysophosphatidylcholine (LPC)-DHA enters the brain than
193 t carotid arteries to compare the effects on lysophosphatidylcholine (LPC)-induced endothelial dysfun
194 acute focal neuroinflammation in the brain, lysophosphatidylcholine (LPC)-induced focal demyelinatio
205 positively curved lipids (ganglioside, GM1; lysophosphatidylcholine, LPCs) and negatively curved lip
206 Medium from endothelial cells exposed to lysophosphatidylcholine (lyso-ECCM), a product of LpL li
207 the production of arachidonic acid (AA) and lysophosphatidylcholine (Lyso-PC) by activating multiple
211 inoleyl hydroperoxide (LAox or 13-HPODE) and lysophosphatidylcholine (lyso-PC), abundant components o
212 plasma membrane, liberating fatty acids and lysophosphatidylcholine (lyso-PC), whereas cPLA(2) acted
214 y phosphatidylcholine (PC) remodeling, and a lysophosphatidylcholine (lysoPC) acyltransferase is thou
215 We report the characterization of three lysophosphatidylcholine (lysoPC) acyltransferases (LPCAT
216 line acyltransferase (LPCAT), which utilizes lysophosphatidylcholine (LysoPC) and fatty acyl-CoA to p
217 implicated PA, phosphatidylcholine (PC) and lysophosphatidylcholine (LysoPC) as potential SOBER1 sub
218 significantly elevated erythrocyte membrane lysophosphatidylcholine (LysoPC) content and circulating
219 Here, we show that the host-derived lipid lysophosphatidylcholine (LysoPC) controls P. falciparum
220 nd colleagues describes a host-derived lipid lysophosphatidylcholine (LysoPC) that regulates sexual c
223 hen endothelial cells (ECs) are incubated in lysophosphatidylcholine (lysoPC), rapid translocation of
224 Progressively lower levels of long-chain lysophosphatidylcholines (lysoPC a C18:2, lysoPC a C20:3
227 and triacylglycerides, sphingomyelins (SMs), lysophosphatidylcholines (LysoPCs), and esterified stero
229 r lysophospholipids as substrates, including lysophosphatidylcholine, lysophosphatidylethanolamine, a
230 dding yeast P4-ATPases Dnf1 and Dnf2 include lysophosphatidylcholine, lysophosphatidylethanolamine, d
231 or a variety of lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine, l
233 olamine, lysophosphatidylglycerol, 1-O-alkyl-lysophosphatidylcholine, lysophosphatidylserine, and lys
234 duct shows lysophospholipase activity toward lysophosphatidylcholine, lysophosphatidylserine, and lys
236 ent in wild-type mice), a 4-fold increase in lysophosphatidylcholine mass in ischemic zones (4.9 nmol
237 ter time points (3 to 24 h), suggesting that lysophosphatidylcholine may, at least in part but not so
238 e production of a novel group of unsaturated lysophosphatidylcholine molecular species and chlorinate
239 lasmalogen cooxidation products, unsaturated lysophosphatidylcholine molecular species containing lin
241 ery endothelial cells to plasmalogen-derived lysophosphatidylcholine molecular species produced marke
242 rated that a novel population of unsaturated lysophosphatidylcholine molecular species was produced b
243 l activated oleosin phosphorylation, whereas lysophosphatidylcholine, oleic acid, and Ca(2+) inhibite
244 y, this process was dependent on exposure of lysophosphatidylcholine on activated cell membranes, whi
245 Recent data support an indirect effect of lysophosphatidylcholine on G2A rather than direct ligand
248 ation was increased by exposure to exogenous lysophosphatidylcholine or lysophosphatidylethanolamine.
249 herosclerotic plaque, including CD40 ligand, lysophosphatidylcholine, or cholesterol crystals, could
251 elin, lysophingomyelin, phosphatidylcholine, lysophosphatidylcholine, or phosphatidic acid among the
252 reas in vivo remyelination is accelerated in lysophosphatidylcholine- or cuprizone-induced demyelinat
253 ividual species of cholesterol esters (CEs), lysophosphatidylcholines, phosphatidylcholines, phosphat
254 ipid compartment in the plasma membrane with lysophosphatidylcholine, previously shown to decrease ch
255 eukin 6 (IL-6) and lipid (neutral lipids and lysophosphatidylcholines) priming activity (P <.05).
258 f this model, the inverted cone-shaped lipid lysophosphatidylcholine rescues secretion from SNARE mut
261 Treatment with increasing concentrations of lysophosphatidylcholine resulted in a dose-dependent red
263 ilis QST713 as well as digitonin, CHAPS, and lysophosphatidylcholine solubilize membranes without sub
264 common endogenous compound classes (e.g., 51 lysophosphatidylcholines spectra) and were then used to
265 complexes formed with diverse lipids such as lysophosphatidylcholine, sulfatide, or mannosyl-phosopho
267 ylcholine, and heightened CCT expression and lysophosphatidylcholine supplementation were equally eff
268 ses phosphatidylcholine as substrate to form lysophosphatidylcholine that has the potential to disrup
269 A2 activity, with the subsequent release of lysophosphatidylcholine that influences macrophage chole
270 se-induced adaptation, we identified various lysophosphatidylcholines that might function as surrogat
273 ge of arachidonate and linoleate esters of 2-lysophosphatidylcholine, the two most abundant polyunsat
274 endent proton fluxes that were stimulated by lysophosphatidylcholine, thus giving rise to a net efflu
276 that facilitates the conversion of palmitoyl-lysophosphatidylcholine to dipalmitoylphosphatidylcholin
277 lypeptide hormone systemin also caused (14)C-lysophosphatidylcholine to increase to levels similar to
278 pholipase D that catalyzes the conversion of lysophosphatidylcholine to lysophosphatidic acid (LPA).
279 n (ATX) is a secreted enzyme that hydrolyzes lysophosphatidylcholine to lysophosphatidic acid (LPA).
280 d for preparing cell-free nerve grafts using lysophosphatidylcholine to remove cells, axons, and myel
281 Inhibition was largely overcome by adding lysophosphatidylcholine to the medium at concentrations
282 recently characterized as a sodium-dependent lysophosphatidylcholine transporter expressed at the blo
288 thesis of CysLTs in response to sPLA(2)-X or lysophosphatidylcholine was inhibited by p38 or JNK inhi
290 bit aortic endothelial cells stimulated with lysophosphatidylcholine, we observed an increase in VCAM
291 -sn-glycero-3-phosphocholine, and of various lysophosphatidylcholines were also significantly elevate
293 oduced when lipid extracts of D.42 plasma or lysophosphatidylcholines were perfused into LPS-pretreat
295 layer bending in a manner similar to that of lysophosphatidylcholine, were here found to promote hemi
296 and of 18:1 in phosphatidylethanolamine and lysophosphatidylcholine, whereas concomitant decreases w
298 metabolites, gamma-glutamyl dipeptides, and lysophosphatidylcholines, which are considered to be inv
299 ns were semi-synthesized by acylation of C20-lysophosphatidylcholine with unsaturated C20 fatty acids
300 ion that adding the positive curvature agent lysophosphatidylcholine would synergistically lower line
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