ライフサイエンスコーパス: m-tyrosine

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1 zes phenylalanine residues to o-tyrosine and m-tyrosine.

2 thesis capacity (Ki) using 6-[(18)F]fluoro-l-m-tyrosine ([(18)F]FMT; a substrate for aromatic amino a

3 fluoro-L-m-tyrosine (6-FMT), 2-[18F]fluoro-L-m-tyrosine (2-FMT) and 6-[18F]fluoro-fluoromethylene-DL-

4 (2-FMT) and 6-[18F]fluoro-fluoromethylene-DL-m-tyrosine (6-F-FMMT), were prepared via electrophilic r

5 he three m-tyrosine analogs, 6-[18F]fluoro-L-m-tyrosine (6-FMT), 2-[18F]fluoro-L-m-tyrosine (2-FMT) a

6 t are resistant to the phytotoxic amino acid m-tyrosine, a structural analog of phenylalanine.

7 Fluorinated m-tyrosine analogs were evaluated as PET imaging agents

8 The three m-tyrosine analogs, 6-[18F]fluoro-L-m-tyrosine (6-FMT),

9 the intravenous injection of [18F]6-fluoro-L-m-tyrosine and compared sampled blood time-activity curv

10 s to 6-[(18)F]fluoro-L-DOPA, 6-[(18)F]fluoro-m-tyrosine, and the translocator protein (TSPO) PET liga

11 ted and identified the nonprotein amino acid m-tyrosine as the major active component.

12 The discovery of m-tyrosine, as well as a further understanding of its mo

13 1], the anti-Parkinson (+/-)-(E)-2,3-methano-m-tyrosine [(+/-)-(E)-2], and the natural product (+/-)-

14 We show that m-tyrosine exposure results in growth inhibition for a w

15 m-Tyrosine fell from 4.24+/-0.99 to 4.03+/-0.97 ng/mL (P

16 6-[(18)F]Fluoro-m-tyrosine (FMT) is a positron emission tomography (PET)

17 mography (PET) radiotracer 6-[(18)F]fluoro-l-m-tyrosine (FMT) is a substrate of the dopamine-synthesi

18 The tracer 6-[18F]fluoro-L-m-tyrosine (FMT) was studied with regard to its biochemi

19 mine (DA) metabolism tracer, [18F]6-fluoro-L-m-tyrosine (FMT) were used to evaluate the relationship

20 The PET ligand was 6-[18F]fluoro-L-m-tyrosine (FMT), imaged prior to, and at two intervals

21 nd the DA metabolism tracer, 6-[18F]fluoro-L-m-tyrosine (FMT), indicating that both are good methods

22 FDG, 6-[18F]fluoro-L-m-tyrosine (FmT), or its major metabolite, 6-[18F]fluoro

23 croPET imaging with the tracer [(18)F]fluoro-m-tyrosine (FMT), the recovery of enzyme activity after

24 levels of o, o'-dityrosine, o-tyrosine, and m-tyrosine in proteins, lipoproteins, and tissue, using

25 m-Tyrosine inhibition of A. thaliana root growth is coun

26 m-Tyrosine is significantly more phytotoxic than its str

27 Its parent compound, L-m-tyrosine (LMT) induces behavioral effects in rodents v

28 t C14 and C15, and the hydroxyl group of the m-tyrosine (m-Tyr) residue as key contributors to compou

29 s of macrocyclic HCV inhibitors started from m-tyrosine methyl ester.

30 rkers of oxidative stress (e.g., o-tyrosine, m-tyrosine, nitrotyrosine, dityrosine, glutathione disul

31 tric synthesis of L-alpha-vinyl analogues of m-tyrosine, ornithine, and lysine, known time-dependent

32 compound optimization identified the valine-m-tyrosine-piperazic acid tripeptide (Val-m-Tyr-Pip) in

33 Arabidopsis thaliana showed incorporation of m-tyrosine, suggesting this as a possible mechanism of p

34 We used PET with 6-[(18)F]fluoro-L-m-tyrosine to quantify dopamine synthesis capacity in vi

35 Using the PET tracer 6-[(18)F]fluoro-l-m-tyrosine, we found strong support for upregulated stri

36 striking contrast, levels of o-tyrosine and m-tyrosine were not elevated in LDL isolated from athero

37 e, and 2- and 3-hydroxyphenylalanine (o- and m-tyrosine) were inactive.

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