ライフサイエンスコーパス: mRNA decay

1 encing multiple steps in AGO2-miRNA-mediated mRNA decay.

2 function for ubiquitin in the regulation of mRNA decay.

3 TS1 did not slow the rate of glucose-induced mRNA decay.

4 rotein but was degraded by nonsense-mediated mRNA decay.

5 kinase, an event that is central to trigger mRNA decay.

6 the idea that PA-X induces host shutoff via mRNA decay.

7 ic processing (P) bodies which are sites for mRNA decay.

8 In turn, AGO2-let-7 triggered target mRNA decay.

9 n, and termination, ribosome biogenesis, and mRNA decay.

10 sense mutation, indicating nonsense-mediated mRNA decay.

11 SIRT1 and VHL mRNAs, and accelerating target mRNA decay.

12 oligo-U-tail as a molecular mark for global mRNA decay.

13 ptional process that occurs in the cytoplasm-mRNA decay.

14 nd how this binding is transformed to induce mRNA decay.

15 MqsA controls GhoT/GhoS through differential mRNA decay.

16 and MEF2C, independently of Staufen-mediated mRNA decay.

17 ture stop codon affects both translation and mRNA decay.

18 in the 3' untranslated region and promoting mRNA decay.

19 nduced chemokine expression due to increased mRNA decay.

20 es and processing bodies, which are sites of mRNA decay.

21 r.796c>u were degraded by nonsense-mediated mRNA decay.

22 directly involved in the control of initial mRNA decay.

23 d to be the rate-limiting step in eukaryotic mRNA decay.

24 ts derived from the 8473T allele and promote mRNA decay.

25 of ribosomes on target mRNAs before causing mRNA decay.

26 e the molecular mechanism of dTIS11-mediated mRNA decay.

27 by inhibiting mRNA translation and promoting mRNA decay.

28 ranslation termination and nonsense-mediated mRNA decay.

29 cleases are not a major contributor to yeast mRNA decay.

30 on, suggesting escape from nonsense-mediated mRNA decay.

31 to viral infection as a result of decreased mRNA decay.

32 not support translation but instead promotes mRNA decay.

33 in protein truncation and nonsense-mediated mRNA decay.

34 lates the stability phase of regulated CD40L mRNA decay.

35 ockdown of L11 rescued miR-24-mediated c-myc mRNA decay.

36 anize mRNA processes such as translation and mRNA decay.

37 shuttling in the mechanism of ARE-dependent mRNA decay.

38 of proteins in the mechanism of ARE-mediated mRNA decay.

39 UTRs were the primary determinants of rapid mRNA decay.

40 ing regulatory small RNAs (sRNAs) to control mRNA decay.

41 rogates the enhancement of nonsense-mediated mRNA decay.

42 bosome as a platform for initiating non-stop mRNA decay.

43 is required for efficient growth and normal mRNA decay.

44 Xrn1, the main 5'-3' exonuclease involved in mRNA decay.

45 poly-(A) tails, the first obligatory step in mRNA decay.

46 enic genes, which triggers nonsense-mediated mRNA decay.

47 e in the cytoplasm and plays a major role in mRNA decay.

48 lational repression in the context of robust mRNA decay.

49 o, how much they contribute to miRNA-induced mRNA decay.

50 d, unexpectedly, enhanced TIS11b activity on mRNA decay.

51 s that recognize a PTC to those that promote mRNA decay.

52 initiation and to inhibit nonsense-mediated mRNA decay.

53 attention has been paid to the regulation of mRNA decay.

54 sion of decapping factors, and gene-specific mRNA decay.

55 d innocuous as a result of nonsense-mediated mRNA decay.

56 exon 8 skipping, causing non-sense-mediated mRNA decay.

57 e a required molecule for regulation of SOX2 mRNA decay.

58 known for degrading the poly(A) tail during mRNA decay.

59 hat HIPK2 and HIPK1 restrict CNOT2-dependent mRNA decay.

60 agments may be generated by co-translational mRNA decay.

61 regulation of COX17 demonstrate its role in mRNA decay.

62 eadenylation, repression, and messenger RNA (mRNA) decay.

63 ther slicer-independent mechanisms of target mRNA decay also exist, and, if so, how much they contrib

64 ity by promoting mRNA stability, as shown by mRNA decay analysis of luciferase and cellular mRNAs.

65 Erh1-Mmi1 complex (EMC), to promote meiotic mRNA decay and facultative heterochromatin assembly.

66 ichia coli, RNase II plays a primary role in mRNA decay and has a preference for unstructured RNA.

67 e role of PARN in miRNA-dependent control of mRNA decay and into the mechanisms behind the regulation

68 lele (C) predicted to cause nonstop-mediated mRNA decay and lower expression of UBASH3A.

69 y recruiting enzymes that function in normal mRNA decay and mRNA degradation is widely thought to occ

70 nding protein Vts1, an important mediator of mRNA decay and mRNA repression whose expression is corre

71 e expression that are supported by regulated mRNA decay and new transcription.

72 of a signaling pathway for regulating global mRNA decay and P-body assembly provides a means to coord

73 The targeting causes mRNA decay and production of secondary siRNAs in a manne

74 ppreciated and potentially regulated step in mRNA decay and raises the question of how other mRNA dec

75 the 2-5A-RNase L system, which triggers SRF mRNA decay and reduced SRF expression.

76 the selective influence of RppH on bacterial mRNA decay and show that RppH-dependent degradation has

77 CISH were marked by m(6)A, exhibited slower mRNA decay and showed increased mRNAs and levels of prot

78 omplexes, LSM1-7 and LSM2-8,that function in mRNA decay and splicing, respectively.

79 f RNA and protein with proposed functions in mRNA decay and storage.

80 at Dcp2 protein modestly contributes to bulk mRNA decay and surprisingly is not detectable in a subse

81 rectly interferes with miR396-mediated AtSVP mRNA decay and synergizes with other effects (e.g. MADS

82 are predicted to result in nonsense-mediated mRNA decay and the absence of WNT1.

83 mRNA turnover keeps a constant ratio between mRNA decay and the dilution of [mRNA] caused by cellular

84 he recent evidence for transcription-coupled mRNA decay and the possible involvement of Snf1, the Sac

85 gous enzymes have important implications for mRNA decay and the regulation of protein biosynthesis in

86 s, how the process of translation influences mRNA decay and the ribonucleases that catalyse decay.

87 s is further regulated by non-sense-mediated mRNA decay and transcription speed.

88 has an unexpected role in the modulation of mRNA decay and translation and that phosphorylation of D

89 he importance of the selective regulation of mRNA decay and translation in regulating gene expression

90 mRNA decay and translation repression, are independent p

91 portant roles in the regulation of splicing, mRNA decay and translation.

92 et the 3'-UTR of claudin-14 mRNA; induce its mRNA decay and translational repression in a synergistic

93 ssociate with decapping factors, and promote mRNA decay and translational repression.

94 sidered the major 3' exonuclease activity in mRNA decay and which is one of four known 3' exonuclease

95 ts precursors, mRNA silencing, regulation of mRNA decay, and regulation of translation.

96 rs of molecular functions like RNA splicing, mRNA decay, and translation control.

97 t levels, including transcription, splicing, mRNA decay, and translation.

98 uclease requirements for general and nonstop mRNA decay are different, and describe a molecular funct

99 We find these effects on mRNA decay are sensitive to the number of slow-moving ri

100 nd transcriptome analyses suggested nonsense mRNA decay as a main impact of mutations.

101 he past 20 years highlight the importance of mRNA decay as a means of modulating gene expression and

102 , Pkc1, is required for and regulates global mRNA decay at the deadenylation step in Saccharomyces ce

103 addition to directing inflammatory cytokine mRNA decay, AUF1 destabilizes cell-cycle checkpoint mRNA

104 ly, mRNA 3'-end processing, gene looping and mRNA decay, but they have also been shown to enter the n

105 cells respond to this widespread cytoplasmic mRNA decay by altering RNA Polymerase II (RNAPII) transc

106 inding protein 1 (CUGBP1) mediates selective mRNA decay by binding to GU-rich elements (GREs) contain

107 smic and is involved in P-body formation and mRNA decay by promoting decapping.

108 regions of select transcripts mediate rapid mRNA decay by recruiting the protein CELF1/CUGBP1.

109 ially organize translation and, potentially, mRNA decay by using the chromosome layout as a template.

110 , indicating that translation initiation and mRNA decay can be modulated independently using the same

111 he processes of translational elongation and mRNA decay communicate is unclear.

112 sphorylation of TTP by MK2 primarily affects mRNA decay downstream of RNA binding by preventing recru

113 lates translation initiation before inducing mRNA decay during zebrafish development.

114 t target mRNAs to the cytoplasmic foci where mRNA decay enzymes are active.

115 foci act as mRNA storage depots rather than mRNA decay facilities.

116 function by promoting degradation of the ARE-mRNA decay factor AUF1 by proteasomes.

117 most significantly changed and included the mRNA decay factor Tristetraprolin.

118 ding surface to successively recruit several mRNA decay factors and show that interaction between tho

119 response to certain stress conditions, many mRNA decay factors are enriched in processing bodies (PB

120 ctivity and impairs the interaction with the mRNA decay factors DCP2, EDC4, and XRN1, but not EDC3, t

121 Suppression of mRNA decay factors leads to the accumulation of oligo-ur

122 nslation termination machinery, and multiple mRNA decay factors, but the precise mechanism allowing t

123 anslationally repressed mRNAs assembled with mRNA decay factors.

124 dation by recruiting cellular messenger RNA (mRNA) decay factors such as the exosome complex and XRN1

125 mputational model demonstrates that the MazF mRNA-decay feedback loop enables proportional control of

126 thod for estimating the rate of differential mRNA decay from RNA-seq data and model mRNA stability in

127 t AUF1 functions in promoting miRNA-mediated mRNA decay globally.

128 Two general pathways of mRNA decay have been characterized in yeast.

129 readily detectable, and previous studies on mRNA decay have used a handful of highly expressed trans

130 ls, translational repression was followed by mRNA decay; however, deleting components of the 5'-3' de

131 sults provide a first step in characterizing mRNA decay in B. burgdorferi and in investigating its ro

132 In this study, we monitored mRNA decay in B. burgdorferi following transcriptional a

133 ng that amlexanox inhibits nonsense-mediated mRNA decay in cells from patients with RDEB that respond

134 tions and structural features reminiscent of mRNA decay in living cells.

135 on with the stim1 3'-UTR and regulated stim1 mRNA decay in opposite directions.

136 veal the global landscape of cotranslational mRNA decay in the Arabidopsis thaliana transcriptome.

137 ced turnover, highlighting the importance of mRNA decay in the control of gene expression.

138 How could mRNA synthesis in the nucleus and mRNA decay in the cytoplasm be mechanistically linked?

139 Patterns of mRNA decay in the wild type were compared with patterns

140 al decreased efficiency of nonsense-mediated mRNA decay in umbilical cord blood, which may reflect sp

141 at Pumilio inhibits translation and enhances mRNA decay independent of Nanos.

142 gnitude of both translational repression and mRNA decay induced by miRNA binding varies greatly betwe

143 Both events reduce the nonsense-mediated mRNA-decay-induced degradation of exon 3*-containing mRN

144 teamine A, an inhibitor of nonsense-mediated mRNA decay, inhibits degradation of aberrant Muc19 trans

145 al protein S15, was used to study aspects of mRNA decay initiation in Bacillus subtilis.

146 , Pelechano et al. report that sequencing of mRNA decay intermediates shows surprisingly tight coupli

147 thway that requires extensive uridylation of mRNA decay intermediates.

148 r of N(6)- methylation, facilitates maternal mRNA decay, introducing an additional facet of control o

149 Indeed, it has been debated whether mRNA decay is a cause or consequence of miRNA-mediated t

150 Regulation of mRNA decay is a critical component of global cellular ad

151 mRNA decay is an essential and active process that allow

152 current understanding of how mammalian cell mRNA decay is controlled by different signalling pathway

153 Regulated mRNA decay is essential for eukaryotic survival but the

154 In eukaryotes, mRNA decay is generally initiated by removal of the poly

155 licing occurs only exceptionally, and target mRNA decay is induced via AGO-dependent recruitment of d

156 In yeast, the major pathway for mRNA decay is initiated by deadenylation followed by dec

157 This is surprising, since mRNA decay is known to be a complex process.

158 Eukaryotic mRNA decay is tightly modulated by RNA-binding proteins

159 at plays a central role in nonsense-mediated mRNA decay, is conformationally converted from a largely

160 actions between TIS11b and components of the mRNA decay machinery revealed that mimicking phosphoryla

161 signal transduction pathways that modify the mRNA decay machinery with consequent effects on decay ra

162 ted transcripts bypass the nonsense-mediated mRNA decay machinery, suggesting the AUG proximity effec

163 ome from 5' exonuclease activity of the host mRNA decay machinery.

164 By accelerating global mRNA decay, many viruses impair host protein synthesis,

165 5'-end integrity by an aberrant-cap-mediated mRNA decay mechanism.

166 ay of specific transcription termination and mRNA decay mechanisms suggests selection for fine-tuning

167 ng noncoding RNAs, RNA binding proteins, and mRNA decay-mediated control of epidermal stem and progen

168 se with essential roles in nonsense-mediated mRNA decay (NMD) and embryonic development.

169 function in both promoting nonsense-mediated mRNA decay (NMD) and preventing nonsense suppression.

170 rotein Y14 is required for nonsense-mediated mRNA decay (NMD) and promotes translation.

171 otein synthesis coupled to nonsense-mediated mRNA decay (NMD) controls a switch in Robo3.2 expression

172 Nonsense-mediated mRNA decay (NMD) controls the quality of eukaryotic gene

173 owed that depletion of the nonsense-mediated mRNA decay (NMD) factor SMG7 or UPF1 significantly induc

174 g repression by hnRNPC and nonsense-mediated mRNA decay (NMD) in the quality control and evolution of

175 Nonsense-mediated mRNA decay (NMD) is a cellular quality-control mechanism

176 Nonsense-mediated mRNA decay (NMD) is a cellular surveillance pathway that

177 Nonsense-mediated mRNA decay (NMD) is a conserved RNA decay pathway that d

178 Nonsense-mediated mRNA decay (NMD) is a eukaryotic mRNA quality control an

179 Nonsense-mediated mRNA decay (NMD) is a eukaryotic process that targets se

180 Nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism

181 Mammalian nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism

182 Nonsense-mediated mRNA decay (NMD) is a quality control mechanism responsi

183 Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that recogniz

184 Nonsense-mediated mRNA decay (NMD) is a translation-dependent RNA quality-

185 Nonsense-mediated mRNA decay (NMD) is a translation-linked process that de

186 Nonsense-mediated mRNA decay (NMD) is an essential eukaryotic process regu

187 n codon (PTC) mutations by nonsense-mediated mRNA decay (NMD) is an important mechanism of long QT sy

188 Nonsense-mediated mRNA decay (NMD) limits the production of aberrant mRNAs

189 by MoMLV RNase H prevents nonsense-mediated mRNA decay (NMD) of mRNAs.

190 I3K) involved in mediating nonsense-mediated mRNA decay (NMD) of transcripts containing premature sto

191 We inhibit the nonsense-mediated mRNA decay (NMD) pathway and show that the PTC-containin

192 The nonsense-mediated mRNA decay (NMD) pathway degrades mRNAs containing long

193 The nonsense-mediated mRNA decay (NMD) pathway functions to degrade both abnor

194 The nonsense-mediated mRNA decay (NMD) pathway is a highly conserved surveilla

195 The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harb

196 The Nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harb

197 The nonsense-mediated mRNA decay (NMD) pathway selectively eliminates aberrant

198 Inactivation of the yeast nonsense-mediated mRNA decay (NMD) pathway stabilizes nonsense mRNAs and p

199 gements are cleared by the nonsense-mediated mRNA decay (NMD) pathway, the process by which cells sel

200 a predicted target of the nonsense-mediated mRNA decay (NMD) pathway.

201 Nonsense-mediated mRNA decay (NMD) represents a eukaryotic quality control

202 Nonsense-mediated mRNA decay (NMD) represents a highly conserved RNA surve

203 nd resulting efficiency of nonsense-mediated mRNA decay (NMD) to eliminate potentially toxic proteins

204 he principal regulators of nonsense-mediated mRNA decay (NMD), a cytoplasmic surveillance pathway tha

205 , in some cases triggering nonsense-mediated mRNA decay (NMD), a highly conserved RNA degradation pat

206 plifying this continuum is nonsense-mediated mRNA decay (NMD), the process wherein a premature stop c

207 ontrol mechanisms, such as nonsense-mediated mRNA decay (NMD), which degrades both abnormal as well a

208 Nonsense-mediated mRNA decay (NMD), which degrades transcripts harboring a

209 Here, we review nonsense-mediated mRNA decay (NMD), which is the best-characterized posttr

210 Transcriptomes of nonsense-mediated mRNA decay (NMD)-impaired and heat-stressed plants share

211 e rapidly degraded through nonsense-mediated mRNA decay (NMD).

212 irst degradative event in non-sense-mediated mRNA decay (NMD).

213 nscript for degradation by nonsense-mediated mRNA decay (NMD).

214 with poor translation and nonsense-mediated mRNA decay (NMD).

215 gene products required for nonsense-mediated mRNA decay (NMD).

216 sembly of mRNPs undergoing nonsense-mediated mRNA decay (NMD).

217 the phenomenon is known as nonsense-mediated mRNA decay (NMD).

218 ression via nonsense-mediated messenger RNA (mRNA) decay (NMD).

219 The general pathways of eukaryotic mRNA decay occur via deadenylation followed by 3' to 5'

220 either the 5' terminus or an internal site, mRNA decay occurs at diverse rates that are transcript s

221 ggest that CUGBP1 coordinately regulates the mRNA decay of a network of transcripts involved in cell

222 breast tumor cells by selectively enhancing mRNA decay of antiapoptotic gene transcripts, including

223 ated AS event leading to a nonsense-mediated mRNA decay of BARD1.

224 ons to exon 11 resulted in nonsense-mediated mRNA decay of full-length, but not the BRCA1-Delta11q is

225 NA stress response, resulting in accelerated mRNA decay of IkappaBalpha, an inhibitor of proinflammat

226 hate-sensing thiM riboswitch, which triggers mRNA decay only as a consequence of translation inhibiti

227 repression at 5' coding regions with limited mRNA decay or cleavage.

228 r with seed sites in target mRNAs to trigger mRNA decay or inhibit translation.

229 RNAs, while partial base-pairing facilitates mRNA decay or inhibits target mRNA translation.

230 ther degraded partially by nonsense-mediated mRNA decay or translated to a stable, truncated subunit

231 ther miRNAs induce translational repression, mRNA decay, or both.

232 At least one additional mRNA decay pathway is also involved.

233 s plakoglobin bypassed the nonsense-mediated mRNA decay pathway, resulting in normal levels of the tr

234 two known mediators of the nonsense-mediated mRNA decay pathway.

235 ich functions in the last step of the 3' end mRNA decay pathway.

236 stabilizing it through the nonsense-mediated mRNA decay pathway.

237 licing to surveillance via nonsense-mediated mRNA decay pathway.

238 F1 and UPF3 act in a translation-independent mRNA decay pathway.

239 A decay and raises the question of how other mRNA decay pathways release protein components of substr

240 Regulated mRNA decay plays a vital role in determining both the le

241 One mechanism of eukaryotic mRNA decay proceeds through an initial deadenylation fol

242 ity could be linked to mRNA silencing and/or mRNA decay processes.

243 NA-binding protein required for ARE-mediated mRNA decay, produce higher levels of Ifna and Ifnb mRNAs

244 of TIS11b plays a key regulatory role in its mRNA decay-promoting function.

245 reviously that, following TNF treatment, the mRNA decay protein tristetraprolin (TTP) is Lys-63-polyu

246 h are aggregates whose core constituents are mRNA decay proteins and RNA.

247 ossible physical links between TTP and other mRNA decay proteins and structures.

248 thod for unbiased estimation of differential mRNA decay rate from RNA-sequencing data by modeling the

249 ts demonstrate that heritable differences in mRNA decay rates are widespread and are an important tar

250 r secondary structures within mRNAs dictates mRNA decay rates by recruiting specific enzyme complexes

251 mine changes in steady-state mRNA levels and mRNA decay rates following 24-hr exposure to noncytotoxi

252 h significant allele-specific differences in mRNA decay rates have higher levels of polymorphism comp

253 Collectively, these results indicate that mRNA decay rates impact transcription and that gamma-her

254 and measured allele-specific differences in mRNA decay rates in a diploid yeast hybrid created by ma

255 , the contribution of heritable variation in mRNA decay rates to gene expression variation has receiv

256 ta instead arose from 50% increased IL-1beta mRNA decay rates, mediated by Hsp27.

257 31% of genes exhibit allelic differences in mRNA decay rates, of which 350 can be identified at a fa

258 gions contributing to allelic differences in mRNA decay rates.

259 profiles revealed that miR396 triggers AtSVP mRNA decay rather than miRNA-mediated cleavage, implying

260 sion through coupling with nonsense-mediated mRNA decay, rather than encode different proteins.

261 a dominant-negative strategy prevented PER1 mRNA decay, reduced tumorigenesis, and increased surviva

262 KA) in the control of TTP family activity in mRNA decay remains largely unknown.

263 How ubiquitin regulates mRNA decay remains unclear.

264 Translational control and messenger RNA (mRNA) decay represent important control points in the re

265 We show that Edc3-mediated RPS28B mRNA decay requires either of two orthologous proteins,

266 inositol-requiring enzyme 1 (IRE1)-dependent mRNA decay (RIDD), which reduce the load of proteins ent

267 degradation, termed regulated IRE1-dependent mRNA decay (RIDD).

268 as the master regulator of 5'-end-dependent mRNA decay, RppH is important for the ability of pathoge

269 of bound mRNA from the translatable pool to mRNA decay sites, such as processing bodies.

270 Staufen1-mediated mRNA decay (SMD) degrades mRNAs that harbor a Staufen1-b

271 Staufen (STAU)1-mediated mRNA decay (SMD) is a posttranscriptional regulatory mec

272 YHB1 mRNA decay stimulation by Puf proteins is also responsiv

273 derived platelet-like particles to show that mRNA decay strongly shapes the nascent platelet transcri

274 Data from mRNA decay studies and quantitative primer extension ass

275 A helicase associated with nonsense-mediated mRNA decay, suggesting that amlexanox inhibits nonsense-

276 LIN41 triggers repression of translation or mRNA decay, suggesting that one factor may use two indep

277 at synaptic activity simultaneously triggers mRNA decay that eliminates Arc mRNA from inactive dendri

278 t1 protein is a central player of eukaryotic mRNA decay that has also been implicated in translationa

279 NA decapping is a central step in eukaryotic mRNA decay that simultaneously shuts down translation in

280 Although Y567X caused nonsense mediated mRNA decay, the amount of TRPV4 protein on western blott

281 ion programs by modulating transcription and mRNA decay.The regulation of overall mRNA turnover keeps

282 ome biogenesis and translation by modulating mRNA decay through a balance of PKA and Hog1 signalling.

283 Here we show that EBP1 promoted AR mRNA decay through physical interaction with a conserved

284 MCPIP1 promotes Gata3 mRNA decay through the RNase domain.

285 Deadenylases promote miRNA-induced mRNA decay through their interaction with miRNA-induced

286 assay directly monitoring deadenylation and mRNA decay to characterize the effects of tethering TOBs

287 uttling leads to defects in Cth2 function in mRNA decay under Fe deficiency.

288 ite, is sufficient to confer glucose-induced mRNA decay upon heterologous transcripts.

289 ow that miR396 triggers AtSVP messenger RNA (mRNA) decay using genetic approaches, a reporter assay,

290 tical step in mRNA turnover, linking MPK4 to mRNA decay via PAT1 provides another mechanism by which

291 ACOT7 mRNA decay was triggered by the microRNA miR-9 in a WIG1

292 uired to induce translational inhibition and mRNA decay when directly tethered to an mRNA, ATP hydrol

293 nation codon that triggers nonsense-mediated mRNA decay when included in the transcript.

294 R sensor IRE1alpha transiently catalyzed DR5 mRNA decay, which allowed time for adaptation.

295 to suppress host protein synthesis via host mRNA decay, which is mediated by endonuclease activity i

296 lization of EGFR transcripts as PLD2 delayed mRNA decay, which prolonged their half-lives.

297 -466i functioned to mediate GM-CSF and IL-17 mRNA decay, which was confirmed by in vitro luciferase a

298 body assembly provides a means to coordinate mRNA decay with other cellular processes essential for g

299 ing demonstrated that Msi2 promotes targeted mRNA decay without affecting translation efficiency.

300 the ADH2 promoter prevented glucose-induced mRNA decay without altering the start site of transcript