ライフサイエンスコーパス: macrocyclic

1 comparison between the devices made with the macrocyclic acceptor and an acyclic control molecule; we

2 dge, this is the first in vivo ADME study of macrocyclic (acyloxy)alkoxy prodrugs, and it remains to

3 and gadobenate dimeglumine compared with the macrocyclic agents gadobutrol and gadoteridol.

4 o cause greater MRI signal changes than some macrocyclic agents, deposition of gadolinium has also be

5 on of gadolinium has also been observed with macrocyclic agents.

6 l-property-based optimization, highly potent macrocyclic ALK inhibitors were prepared with good absor

7 eactions, generating 14- to 21-membered ring macrocyclic alkenes in 40-70% yield and 96:4-98:2 Z:E se

8 them to be converted stereoselectively to E-macrocyclic alkenes.

9 Peptide stapling is a method for designing macrocyclic alpha-helical inhibitors of protein-protein

10 This effort resulted in the discovery of a macrocyclic amide linker which was found to form a key h

11 of bottromycin stems from its unprecedented macrocyclic amidine and rare beta-methylated amino acid

12 We recently identified a novel family of macrocyclic amidinoureas showing potent antifungal activ

13 onding 2 + 2, 3 + 3, 4 + 4, 6 + 6, and 8 + 8 macrocyclic amines.

14 The structures of a new family of macrocyclic analogues of combretastatins B combining oxy

15 Finally, we evaluated macrocyclic analogues of the BH3 domain of the BIM prote

16 Multiple macrocyclic analogues of the peptide transportan-10 were

17 highly flexible solvent molecules sitting in macrocyclic and intermolecule void spaces.

18 His influence on macrocyclic and supramolecular chemistry has been pervas

19 c community and fueled important advances in macrocyclic and supramolecular chemistry.

20 Cyclophanes are a venerable class of macrocyclic and/or cage compounds that often feature hig

21 Confinement within the macrocyclic architecture slows the inversion of the o-ph

22 ht into reactions inside particularly shaped macrocyclic architecture, including metal-mediated organ

23 rough a C(sp(2))-H activation, using a model macrocyclic arene substrate.

24 le benziporphyrins are essentially devoid of macrocyclic aromatic character, and azuliporphyrins fall

25 sentation for depicting the bonding of large macrocyclic aromatic compounds.

26 at concentrations up to 100 muM, whereas the macrocyclic AS-48 is potently active against pathogenic

27 es of oligomers formed in the solid state by macrocyclic beta-sheet 3 represent a new mode of supramo

28 X-ray crystallography reveals that the macrocyclic beta-sheet assembles to form double-walled n

29 r describes the supramolecular assembly of a macrocyclic beta-sheet containing residues 16-22 of the

30 In aqueous solution, macrocyclic beta-sheet peptide 1 and homologue 2a form h

31 In the solid state, macrocyclic beta-sheet peptide 1 assembles to form hydro

32 The X-ray crystallographic structure of macrocyclic beta-sheet peptide 3 was determined at 1.75

33 er assemblies formed in the solid state by a macrocyclic beta-sheet peptide containing the Abeta(15-2

34 n of residues 11-17 of IAPP (RLANFLV) into a macrocyclic beta-sheet peptide results in a monomeric pe

35 In this paper, we study the assembly of macrocyclic beta-sheet peptides that contain residues 17

36 The reactivity of macrocyclic bis-enones in Diels-Alder reactions was exam

37 Here we report the discovery of a macrocyclic bis-thiourea derivative that catalyzes stere

38 Carbohydrate receptors combining a macrocyclic building block and two flexible side arms we

39 Here we demonstrate that macrocyclic calixarenes can disrupt binding of PHD finge

40 lts on functional, aromatic, rigid, sigma,pi-macrocyclic carbo-benzene archetypes of various substitu

41 pro-aromatic" congeners, i.e. rigid sigma,pi-macrocyclic carbo-quinoids.

42 6-dimethoxybenzyne to form the corresponding macrocyclic carbon frameworks.

43 aper substrate with a metalloporphyrin based macrocyclic catalyst ink that can electrochemically redu

44 ic guest engaging in H-G interactions with a macrocyclic cavity, provides a novel strategy for manipu

45 f oAzoBox(4+) the guest is expelled from the macrocyclic cavity.

46 of the methoxy substituents relative to the macrocyclic cavity.

47 ical shifts of non-exchangeable protons from macrocyclic chelates (e.g., DOTP(8-)) complexed with par

48 tissue concentrations of multiple linear and macrocyclic chelates in a rat model to better understand

49 Macrocyclic chelators have been widely employed in the r

50 amate urea scaffold and utilize a variety of macrocyclic chelators, namely NOTA(3), PCTA(4), Oxo-DO3A

51 By combining macrocyclic chemistry with density functional theory cal

52 Here we show that macrocyclic cinnamate dimers combine these productive st

53 olution reaction catalyzed by a tetradentate macrocyclic cobalt complex with the formula [LCo(III)Cl2

54 dy, the two recently synthesized 13-membered macrocyclic competitive IRAP inhibitors HA08 and HA09, w

55 Another macrocyclic complex, [Ni(TMC)](+), is deployed as a CO s

56 a behavior which is similar to that of iron macrocyclic complexes and suggests a contribution of the

57 Several reaction modalities of these macrocyclic complexes were uncovered.

58 via allosteric information transfer between macrocyclic complexes, we describe the thermodynamic and

59 ten critical in such cases: the potency of a macrocyclic compound can depend on the stereochemistry o

60 f-assembled system based on a zinc porphyrin macrocyclic compound, a bidentate ligand (1,4-diazabicyc

61 Macrocyclic compounds are central to the development of

62 Hybrid [n]arenes, the class of medium-sized macrocyclic compounds consisting of different alkoxybenz

63 he cathodic voltammetric behavior of all the macrocyclic compounds containing two or more quinone uni

64 A new family of pseudopeptidic macrocyclic compounds has been prepared involving an ani

65 e loops that are well-suited to mimicry with macrocyclic compounds, and loops that are most similar t

66 he beginning of research on cyclic polyether macrocyclic compounds.

67 esign of appropriate synthetic routes to new macrocyclic compounds.

68 gy for construction of this ring system in a macrocyclic core has not been investigated.

69 has been applied toward the synthesis of the macrocyclic core of complex pharmaceutical vaniprevir.

70 able route to accessing the fully elaborated macrocyclic core of neopeltolide.

71 haropolyspora erythraea that synthesizes the macrocyclic core of the antibiotic erythromycin 6-deoxye

72 lariat-type cyclic depsipeptide of which the macrocyclic core possesses modified amino acids, includi

73 Optimization of the macrocyclic core residues and N-acyl side chain culminat

74 CAP can be considered as macrocyclic counterpart of PTA with the electron-donatin

75 The direct incorporation of macrocyclic cyclidene complexes into DNA via automated s

76 ort a new and diversity-oriented approach to macrocyclic cyclophanes by a Grignard reaction, followed

77 In this study, a set of macrocyclic cyclophilin inhibitors was synthesized based

78 Using the largazole macrocyclic depsipeptide structure as a starting point f

79 The resulting macrocyclic depsipeptides are model compounds for natura

80 proach to discrete collections of oligomeric macrocyclic depsipeptides using an oligomerization/macro

81 ring-closing metathesis procedure to prepare macrocyclic derivatives of 3,4-disusbstituted pyridines,

82 nts but not to polycyclic musk odorants or a macrocyclic diester musk odorant.

83 e voltage plateaus observed for a homologous macrocyclic dimer and an acyclic derivative of pyromelli

84 e-helical superstructure from an enantiopure macrocyclic dimer which adopts two diastereoisomeric con

85 s dictated by the choice of the enantiomeric macrocyclic dimer.

86 ed from coordination-driven self-assembly of macrocyclic dipalladium complexes and tetracarboxylate z

87 yclization describes the ring closure of the macrocyclic diterpene casbene.

88 f Euphorbia lathyris L. contains a series of macrocyclic diterpenoids known as Euphorbia factors.

89 ways of ingenol mebutate and other bioactive macrocyclic diterpenoids.

90 acid representing the C13-C19 segment of the macrocyclic domain present in the immunosuppressive agen

91 s of the two olefinic protons located at the macrocyclic double bond was established.

92 Analysis of approximately 100 macrocyclic drugs and clinical candidates revealed that

93 available metathesis approach for accessing macrocyclic E-olefins entails selective removal of the Z

94 site-specific integration of fragments into macrocyclic entities has not yet found application in th

95 cavity and hydrophilic external surface are macrocyclic entities that display a combination of molec

96 The distinctive macrocyclic environment creates a long-sought opportunit

97 Macrocyclic enyne and dienyne complexes were readily syn

98 formation generates a strained, 1,3-bridged, macrocyclic enyne.

99 polar direct thrombin inhibitor as a single, macrocyclic esterase-cleavable (acyloxy)alkoxy prodrug.

100 trumental in the designing or redesigning of macrocyclic frames, particularly in the search for adjus

101 A macrocyclic furan-containing CPP precursor was used for

102 ation and oxygenation, (4) substitution, (5) macrocyclic fusion, (6) core bridging, (7) ring contract

103 Incorporation of a methyl group onto a macrocyclic FVIIa inhibitor improves potency 10-fold but

104 e designed and synthesized a novel series of macrocyclic FVIIa inhibitors.

105 A novel series of macrocyclic FXIa inhibitors was designed based on our le

106 The macrocyclic FXIa series, exemplified by compound 16, had

107 ct of at least five serial injections of the macrocyclic gadolinium-based contrast agent (GBCA) gadot

108 creases after repeated administration of the macrocyclic gadolinium-based contrast agents (GBCAs) gad

109 effect of more than 20 serial injections of macrocyclic gadolinium-based contrast agents (GBCAs) on

110 linear GBCA (gadopentetate dimeglumine) or a macrocyclic GBCA (gadoterate meglumine) were analyzed re

111 xamine the association between the number of macrocyclic GBCA administrations and DeltanSIDN or Delta

112 ts The mean +/- standard deviation number of macrocyclic GBCA administrations was 22.2 +/- 10.6 admin

113 t not eliminated following administration of macrocyclic GBCA chelates in lieu of linear chelates.

114 ho had received 10-44 administrations of the macrocyclic GBCA gadobutrol (0.1 mmol/kg of body weight)

115 after a mean of 8.6 serial injections of the macrocyclic GBCA gadoterate meglumine in pediatric patie

116 BCA gadopentetate dimeglumine but not by the macrocyclic GBCA gadoterate meglumine.

117 ant linear association between the number of macrocyclic GBCA injections and DeltanSIDN (r = 0.69, P

118 cement was observed in the DN after multiple macrocyclic GBCA injections.

119 d in two patients who had received 37 and 44 macrocyclic GBCA injections.

120 dicates that 20 or more serial injections of macrocyclic GBCAs administered with on average 3 months

121 P < .00001) and less than that for nonionic macrocyclic GBCAs at 16 (95% CI: 14, 19) per 10 000 admi

122 ing for reference) with the exclusive use of macrocyclic GBCAs gadoterate meglumine and gadobutrol we

123 find this effect after serial injections of macrocyclic GBCAs in adults.

124 ultiple intravenous administrations of these macrocyclic GBCAs in children were not associated with a

125 rison with those of ionic linear or nonionic macrocyclic GBCAs.

126 (GBCAs) but had received many injections of macrocyclic GBCAs.

127 who had received 37 and 44 standard doses of macrocyclic GBCAs.

128 a Z-selective olefin cross metathesis and a macrocyclic Glaser-Hay coupling as key steps.

129 ardized difference of 0.81) than that in the macrocyclic group, which did not differ from 0 (DN, 0.00

130 Leaf rust of barley is caused by the macrocyclic, heteroecious rust pathogen Puccinia hordei,

131 We derived macrocyclic HIV-1 antagonists as a new class of peptidom

132 dienophile substrate are included inside the macrocyclic host cavity, suggesting that contiguity and

133 s, becomes complexed with the tetra cationic macrocyclic host CBPQT(4+) , swelling occurred as a resu

134 A macrocyclic host for fullerenes containing two sExTTF un

135 h-type aptamer strategy based on a signaling macrocyclic host-dye system.

136 llar to hexagonal columnar phase mediated by macrocyclic host-guest (H-G) interactions between the ma

137 he most recognizable supramolecular motifs - macrocyclic host-guest complexes - afford logical applic

138 ls, cavity polarities, and shapes of the two macrocyclic hosts could account for the formation of the

139 cenylguanidinium derivative (FcG(+)) and the macrocyclic hosts cucurbit[7]uril (CB7) and cucurbit[8]u

140 plex formation behavior of 1Cl3 with the two macrocyclic hosts results in the stabilization of differ

141 clusion complex formation with two different macrocyclic hosts, cucurbit[7]uril (CB[7]) and beta-cycl

142 physically cross-linked with cucurbit[8]uril macrocyclic hosts.

143 The macrocyclic hydroxamate-based pan-MMP inhibitor coupled

144 lts in 2 + 2, 3 + 3, 4 + 4, 6 + 6, and 8 + 8 macrocyclic imine condensation products.

145 A macrocyclic inhibitor incorporating this constraint was

146 Grazoprevir is a potent pan-genotype and macrocyclic inhibitor of hepatitis C virus (HCV) NS3/4A

147 We identified a novel macrocyclic inhibitor of Plasmodium falciparum with nano

148 Starting with an aminoisoquinoline P1-based macrocyclic inhibitor, optimization of the P' groups led

149 nase domain in complex with a small-molecule macrocyclic inhibitor.

150 stry effort to develop novel P2 cyclopentane macrocyclic inhibitors guided by HCV NS3 protease assays

151 e first class of oxadiazole-based, permeable macrocyclic inhibitors of norovirus 3CL protease.

152 mplate enables further optimization of these macrocyclic inhibitors.

153 acrocycles, strained cycloalkynes, and a key macrocyclic intermediate toward the synthesis of aceroge

154 ortholog of Olfr235 and Olfr1440 responds to macrocyclic ketone and lactone musk odorants but not to

155 omide and a thioester has been extended to a macrocyclic ketone synthesis.

156 ediated one-pot ketone synthesis to form the macrocyclic ketone.

157 phic analyses of the 8-, 9-, and 10-membered macrocyclic lactam starting materials as well as certain

158 d for the simultaneous determination of four macrocyclic lactones (ML) (abamectin, doramectin, iverme

159 Macrocyclic lactones ranging in size from twelve- to sev

160 The highly complex thiosemicarbazone-based macrocyclic libraries contain both [2]catenanes and sequ

161 peroxo complexes bearing a common tetraamido macrocyclic ligand (TAML), namely [(TAML)Fe(III) (O2 )](

162 catalyst, [Ni(MeTAA)], featuring a tetraaza macrocyclic ligand (tetramethyltetraaza[14]annulene (MeT

163 /Mg(II) complex coordinated by a symmetrical macrocyclic ligand are reported.

164 e nickel(II) complex (1) of the tetradentate macrocyclic ligand bearing a 2,6-pyridinedicarboxamidate

165 The main features of iron-tetra-amido macrocyclic ligand complex (a sub-branch of TAML) cataly

166 gonal prismatic coordination provided by the macrocyclic ligand gives intrinsically more stable molec

167 mplex with the formula [LCo(III)Cl2](+) (L = macrocyclic ligand), [Ru(bpy)3](2+) photosensitizer, and

168 observed upon oxygen incorporation into the macrocyclic ligand.

169 iron(III)-superoxo complex with a tetraamido macrocyclic ligand.

170 Iron complexes of tetra-amido macrocyclic ligands are important members of the suite o

171 binding site has enabled the design of novel macrocyclic ligands that are themselves potent IL-17A an

172 Dicobalt complexes supported by flexible macrocyclic ligands were used to target the generation o

173 s are mainly based on linear polydentate and macrocyclic ligands.

174 mophoric interaction among the pi-conjugated macrocyclic linkers was studied within three tetraphenyl

175 Producing macrocyclic mesogens that are responsive to guest encaps

176 Macrocyclic metal complexes and p-benzoquinones are comm

177 -space electron delocalization in triangular macrocyclic molecules that exhibit a single well-defined

178 tems have emerged only recently as promising macrocyclic molecules to fabricate environmentally benig

179 tion by four deprotonated amide nitrogens in macrocyclic motifs is the signature of TAMLs where the m

180 ween CO2 reduction and proton reduction of a macrocyclic multi-electron catalyst is steered toward CO

181 total synthesis of anticancer and antifungal macrocyclic natural product disorazole C1 is reported.

182 Cocrystal structures of these macrocyclic natural product inhibitors in a modified por

183 Despite these hurdles, macrocyclic natural products, including FK506, rapamycin

184 as (5) fused, (6) bridged bicyclic, and (7) macrocyclic nitrogen heterocycles.

185 l-substituted 12-, 13-, 17-, and 21-membered macrocyclic nucleoside analogues with polyether linkages

186 A novel macrocyclic octadentate ligand incorporating terephthala

187 icient methods for selective modification of macrocyclic oligomers are rare, mostly because restricti

188 for the tailored synthesis of sophisticated macrocyclic oligomers.

189 The preliminary results indicate that macrocyclic oligoTEAs with just two-to-three cationic ch

190 owed access to countless biologically active macrocyclic organic molecules, even for large-scale prod

191 ided a fundamental change in the approach to macrocyclic organometallic chemistry.

192 The tetrameric cage contains two macrocyclic panels and exhibits D2h symmetry.

193 Based on this screen, a macrocyclic peptide 22 involving two non-natural amino a

194 The crystal structure of an iPGM macrocyclic peptide complex illuminated an allosteric, l

195 Additionally, a macrocyclic peptide containing a proline turn element is

196 Each macrocyclic peptide contains the heptapeptide sequence b

197 ers contain a sequence that is released as a macrocyclic peptide during post-translational processing

198 es by exploiting the reactivity of transient macrocyclic peptide imines toward inter- and intramolecu

199 Using this approach, an optimized macrocyclic peptide inhibitor (HL2-m5) was obtained that

200 re we tested the effect of RA101295, a 2-kDa macrocyclic peptide inhibitor of C5 cleavage, using in v

201 We describe a novel beta-hairpin macrocyclic peptide JB-95 with potent antimicrobial acti

202 affinity maturation through the screening of macrocyclic peptide libraries produced in E. coli cells.

203 ich lariat-like ligands from an mRNA-display macrocyclic peptide library containing >10(12) members.

204 We synthesized a macrocyclic peptide mimic of the beta-hairpin from EC869

205 This first-in-class macrocyclic peptide modulator of the hedgehog pathway is

206 enoid donor analog and a panel of linear and macrocyclic peptide substrates.

207 This strategy led to the discovery of macrocyclic peptide-peptoid hybrids with high CXCR7 bind

208 d biosynthesis of streptide, a streptococcal macrocyclic peptide.

209 sunflower proalbumins into an albumin and a macrocyclic peptide.

210 Macrocyclic peptides can interfere with challenging biom

211 the stable structures that can be adopted by macrocyclic peptides composed of l- and d-amino acids by

212 res of three families of oligomers formed by macrocyclic peptides containing a heptapeptide sequence

213 efforts highlighting the important roles of macrocyclic peptides in expanding chemical diversity for

214 cking that allows the affinity maturation of macrocyclic peptides taking non-natural amino acids into

215 l requirements for potent HDAC inhibition by macrocyclic peptides using the azumamides along with a s

216 Structural interrogation of the linear and macrocyclic peptides using variable-temperature NMR and

217 ficient and mild method for the synthesis of macrocyclic peptides via nitrogen arylation from unprote

218 ented workflow allows the screening of large macrocyclic peptides with diverse modifications thereby

219 trB provides a new route for biosynthesizing macrocyclic peptides.

220 tructure-based drug design and optimization, macrocyclic peptidomimetic molecules bearing both a lipo

221 ein the design, synthesis, and evaluation of macrocyclic peptidomimetics that bind to WD repeat domai

222 -diol-containing dienes in the generation of macrocyclic phosphates with potential synthetic and biol

223 based on alkali metal cation binding with a macrocyclic "pincer-crown ether" ligand.

224 New macrocyclic plasmin inhibitors based on our previously o

225 al chemistry of carbo-mers and in particular macrocyclic-polycyclic representatives constituting a na

226 between an organoplatinum square and a {2+2} macrocyclic polyether containing two 1,5-dioxynaphthalen

227 A tristable [2]catenane, composed of a macrocyclic polyether incorporating 1,5-dioxynaphthalene

228 Mandelalides A-D (1-4) are macrocyclic polyketides known to have an unusual bioacti

229 erials (e.g. star polymers, polymer brushes, macrocyclic polymers, and hyperbranched polymers) combin

230 ery effective for directing the synthesis of macrocyclic porphyrin oligomers consisting of six or sev

231 his study has revealed the 3D structure of a macrocyclic precursor protein and provided important mec

232 the energy barrier for the formation of the macrocyclic product.

233 ranged from highly strained (k = 11, 12) to macrocyclic products (k = 22, 24).

234 The main macrocyclic products are hybrid [n]arenes consisting of

235 Macrocyclic products bearing non-native and rigidifying

236 The macrocyclic products were highly diatropic and produced

237 f ring closing reactions to form the desired macrocyclic products.

238 enabled the synthesis of potent pyridone and macrocyclic pyridone inhibitors exhibiting single digit

239 Only a few examples of artificial macrocyclic receptors capable of binding these zwitterio

240 The selective functionalization of macrocyclic receptors remains extremely challenging beca

241 rophobic cross-linkers stabilize the fold by macrocyclic restraints, and they also form an integral p

242 nzyne diradical across a diyne moiety of the macrocyclic ring affords an aromatic ring that must unde

243 In the absence of macrocyclic ring constraints, few synthetic systems, pos

244 38]annulenoid oxidized form display residual macrocyclic ring currents.

245 Translation of a macrocyclic ring from one station to another on a molecu

246 hloride anions are bound above and below the macrocyclic ring of the 2 + 2 amine, one chloride anion

247 y, and (2)H SSNMR demonstrated that the 24C6 macrocyclic ring of the pillared MIM strut is now free e

248 e pathway must involve chelation, amidation, macrocyclic ring reduction, lactamization and carbocycli

249 The effect of macrocyclic ring size on the reaction rate of oxidative

250 r sulfonic (2) or carboxylic acids (3, 4) as macrocyclic ring substituents: the aminocaproate derivat

251 mples of catalyst-controlled stereoselective macrocyclic ring-closing metathesis reactions that gener

252 monoaryloxide pyrrolide (MAP) complex and a macrocyclic ring-closing metathesis that affords a trisu

253 14-membered ring stapled peptide by means of macrocyclic ring-closing metathesis.

254 controlled E-selective cross-metathesis and macrocyclic ring-closing reactions, where E-butene serve

255 er-Wadsworth-Emmons olefination to forge the macrocyclic ring.

256 ry covering each position along thiocillin's macrocyclic ring.

257 enanes - molecules consisting of interlocked macrocyclic rings - have been prepared by templation str

258 resorcin[4]arene cavitands, the 14-membered macrocyclic rings that contain the P horizontal lineO gr

259 ingly explored as a reliable method to close macrocyclic rings, but there are no prior examples of an

260 ides tethered to chiral sulfoxide-containing macrocyclic rings.

261 -dialkoxybenzene units are flexible parts of macrocyclic rings.

262 the Asn and Ala positions of a reported AGRP macrocyclic scaffold (c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-DPro

263 Discovery of this potent, selective macrocyclic scaffold opens new possibilities for the dev

264 The data show that macrocyclic scaffolds and mechanism-based inhibition are

265 Constrained macrocyclic scaffolds are recognized as challenging synt

266 hat explain how orthologs can generate rigid macrocyclic scaffolds of different sizes.

267 ass of thiazole-containing, highly modified, macrocyclic secondary metabolites made from ribosomally

268 These systems consist of tubular macrocyclic sections that are tightly capped on one side

269 The stabilizing features of a macrocyclic sesquiterpene-derived cation were explored u

270 Macrocyclic small molecules are attractive tools in the

271 id access to discrete collections of complex macrocyclic small molecules from medium (18) to large (6

272 ith respect to their animal/plant origin and macrocyclic, small molecule or herbal active constituent

273 -10) has been achieved by employing a simple macrocyclic solute-MeMeCH2-as a kinetic template.

274 Efficient, elegant, and high-yielding (for macrocyclic species) synthetic routes to two novel alkyn

275 Computational modeling of thiocillin's macrocyclic structure revealed a striking requirement fo

276 erism due to restricted bond rotation in the macrocyclic structure, as demonstrated by NMR studies.

277 sociated with ionicity, protein binding, and macrocyclic structure.

278 athesis enabled the synthesis of 51 distinct macrocyclic structures bearing 48 unique scaffolds in on

279 that the incorporation of photoswitches into macrocyclic structures is a particularly attractive solu

280 c motifs is the signature of TAMLs where the macrocyclic structures vary considerably.

281 ically robust enough to be incorporated into macrocyclic structures, thereby significantly expanding

282 he ring opening polymerization of unstrained macrocyclic structures.

283 tion reactions utilizing a model aryl halide macrocyclic substrate.

284 Rhomboidal macrocyclic subunits of graphdiyne-like nanoribbon (GDNR

285 molecular chemists - with their expertise in macrocyclic synthesis and measuring supramolecular inter

286 last five decades, these naturally occurring macrocyclic systems have emerged only recently as promis

287 on, and reactivity of porphyrins and related macrocyclic systems.

288 ociated with topologically planar conjugated macrocyclic systems.

289 From this perspective, a macrocyclic template was attractive for a number of reas

290 can, in principle, be applied to any type of macrocyclic template.

291 tility of this approach for the synthesis of macrocyclic tertiary enamide natural products.

292 Use of a macrocyclic tetracarbene ligand, which is topologically

293 t on the synthesis of two series of isomeric macrocyclic tetraimines based on bis-alkynylbenzene diam

294 A macrocyclic tetralactam host is threaded by a highly flu

295 Nosiheptide, a member of the e series of macrocyclic thiopeptide natural products, contains a sid

296 the expression of Nisin variants with novel macrocyclic topologies.

297 aration of hybrid ionic materials comprising macrocyclic triradical trianions with spin-frustrated gr

298 Kawaguchipeptins A and B, two macrocyclic undecapeptides reported earlier from Microcy

299 Only macrocyclic walker-track conjugates are efficiently hydr

300 In this work, a series of heptadentate macrocyclic YbDO3A-trisamide complexes with delta-chiral