ライフサイエンスコーパス: macronuclei

1 diffuse and is gradually lost in developing macronuclei.

2 f normal total DNA content in the developing macronuclei.

3 r own transcription when placed into somatic macronuclei.

4 the predominant linker histone in vegetative macronuclei.

5 ion-associated HAT activity from Tetrahymena macronuclei.

6 e major perchloric-acid-soluble protein from macronuclei.

7 which encodes an HP1-like protein, Hhp1p, in macronuclei.

8 the sites of DNA replication within Euplotes macronuclei.

9 t presumably comprise repressed chromatin in macronuclei.

10 re not evenly distributed between micro- and macronuclei.

11 the accumulation of DSBs in both micro- and macronuclei.

12 DNA elimination structures within developing macronuclei.

13 dies in micronuclei, that is not detected in macronuclei.

14 f the M or R element during formation of new macronuclei.

15 ved chromosomal junctions left behind in the macronuclei.

16 mic germline deficiencies but proficient old macronuclei.

17 NA sequences from their newly formed somatic macronuclei, a result that shows that this Dicer-related

18 able of RAD51 expression from their parental macronuclei and are homozygous, rad51 nulls in their ger

19 uplex structures in telomeres of Stylonychia macronuclei and in the promoter of c-myc in human cells

20 p80/p95, telomeres become elongated in both macronuclei and micronuclei.

21 in the nucleoli of transcriptionally active macronuclei and missing altogether from transcriptionall

22 e breakage in a sub-population of developing macronuclei and promotes alternative processing by a Cbs

23 before DNA rearrangements in the developing macronuclei (anlagen) causes aberrant anlage DNA loss, s

24 in Tetrahymena, is found only in developing macronuclei (anlagen) in association with chromatin cont

25 s up-regulated during development of the new macronuclei (anlagen).

26 a 55-kDa polypeptide (p55) from Tetrahymena macronuclei as a catalytic subunit of a transcription-as

27 ammed DNA rearrangements occur in developing macronuclei, as for immunoglobulin gene rearrangements i

28 are most abundant when developing micro- and macronuclei begin their differentiation.

29 ific sequences during development of the new macronuclei but not for the RNA interference pathway, th

30 Macronuclei, but not micronuclei, contain a 36-kDa polyp

31 In Tetrahymena, transcriptionally active macronuclei, but not transcriptionally inert micronuclei

32 ts germline micronuclear genome from somatic macronuclei by excising thousands of internal eliminated

33 In developing macronuclei, chimeric primers had two fates: nucleotides

34 ng genes encoding rRNA within parental (old) macronuclei, consistently failed to excise chromosomal c

35 Although both micronuclei and macronuclei contain H3 in typical nucleosomal structures

36 support, extracts from micronuclei, but not macronuclei, contain a kinase activity that resembles so

37 ahymena thermophila conjugation, new somatic macronuclei develop from a common zygotic nucleus derive

38 Macronuclei divide amitotically without overt chromosome

39 y cells did not grow because the new somatic macronuclei do not have any alpha-tubulin genes.

40 for the differentiation of micronuclei into macronuclei during development.

41 Pdd1p also associates with parental macronuclei during terminal stages of apoptosis.

42 asymmetrically distributed to developing new macronuclei early in their differentiation during the se

43 otic nuclear division, and subsequently, new macronuclei fail to develop despite parental macronuclea

44 re deleted during the development of somatic macronuclei from germline micronuclei, at each sexual ge

45 phylogenetic impact, such as the micro- and macronuclei in ciliates).

46 lation at lysine 4 appears to be specific to macronuclei in Tetrahymena, we suggest that this modific

47 earrangement processes in developing zygotic macronuclei, including excision of internal eliminated s

48 n contrast to many eukaryotes, histone H1 of macronuclei is highly phosphorylated during interphase.

49 r dimorphism through the presence of somatic macronuclei (MAC) and germline micronuclei (MIC).

50 Ciliated protozoa have two kinds of nuclei: Macronuclei (MAC) and Micronuclei (MIC).

51 rotein was identified and characterized from macronuclei of the ciliated protozoan Tetrahymena thermo

52 Microinjection of PAK11 DNA into macronuclei of wild-type cells results in clonal transfo

53 In isolated macronuclei, p43 largely colocalizes with telomerase RNA

54 Here we report that, in developing macronuclei, Pdd1p localizes to electron-dense, heteroch

55 ike Pdd1p, which also localizes to apoptotic macronuclei, Pdd2p appears to be restricted to a higher

56 line knockout cells with wild type parental macronuclei proceed through mating but arrest at late ma

57 of exogenous deletion elements into parental macronuclei provides us with an epigenetic means to esta

58 Replicating macronuclei stained with Orc2 antibodies throughout deve

59 carried on these copies eventually generates macronuclei that are pure for one allele or the other.

60 i that divide mitotically but not in somatic macronuclei that divide amitotically.

61 ms multiple nuclear bodies in the developing macronuclei that do not colocalize with heterochromatic

62 of a 28-kDa polypeptide (p28) in Tetrahymena macronuclei that shares several features with the well s

63 demonstrate that gene transfer from somatic macronuclei to germ-line micronuclei occurs rarely if at

64 In contrast, telomerase from vegetative macronuclei used only the cleavage pathway.

65 rase from vegetative and developing Euplotes macronuclei using chimeric primers that contained non-te

66 n-telomeric 3' ends was lost when developing macronuclei were lysed and the contents purified on glyc

67 ts (G4T2 repeats) in Tetrahymena thermophila macronuclei were shown previously to be packaged in a no

68 tricted to mitotically dividing micronuclei; macronuclei, which are amitotic, showed no defects.

69 In contrast, macronuclei, which divide amitotically, phosphorylate li

70 ed to the unique genetic property of ciliate macronuclei, which transcribe actively and divide withou

71 cent M and R elements, by loading vegetative macronuclei with these elements prior to sexual conjugat