ライフサイエンスコーパス: main chain

1 nor-acceptor building block into the polymer main chain.

2 the redox state of ferrocene in the polymer main chain.

3 carbene (NHC) orthogonally connected to its main chain.

4 15), while the remaining contacts are to the main chain.

5 dergoing a change in the overall fold of the main chain.

6 group attached to the CoNP colloidal polymer main chain.

7 Tra1 enabled tracing of the majority of its main chain.

8 of bonds orthogonal to an elongated polymer main chain.

9 onfiguration between the side chains and the main chain.

10 arity primarily due to the trajectory of the main chain.

11 nhancing electronic delocalization along the main-chain.

12 table to the formation of polarons along the main chains.

13 he hydrogen-bonding interactions between the main chains.

14 Phe(B25), which mimics the Phe(B24) side and main chains.

15 nyl-alpha-aminoamide-substituted polypeptide main chains.

16 by insertion of a single amino acid into the main chain, adjacent to cysteine 147.

17 a canonical conformation in which the ligand main chain adopts an extended beta-strand conformation b

18 sp174 form ion-pairing interactions with the main chain alpha-carboxyl and alpha-amino-groups, respec

19 minus to investigate whether the polypeptide main chain amide bonds in the N-terminus of SDF-1alpha p

20 ng and internalization is dependent upon the main chain amide bonds in the N-terminus of SDF-1alpha.

21 Thr(352), and stabilize an oxyanion hole via main chain amide hydrogen bonds.

22 n chain carbonyl of the P(5) residue and the main chain amide of amino acid 137 of the protease, whic

23 firms that the oxyanion is stabilized by the main chain amide of Ser-201 and by the side chains of Hi

24 unlikely source of this proton is the Cys302 main chain amide.

25 ative oxyanion hole that is constituted of a main-chain amide (Ser-201) and two conserved side chains

26 ists between adjacent carbonyl groups of the main-chain amide bonds.

27 Unexpectedly, the main-chain amide group of Gln 230 in the universally con

28 tive-state hydrogen-exchange NMR analysis of main-chain amide hydrogens.

29 As seen for the RF1 complex, the main-chain amide nitrogen of glutamine in the GGQ motif

30 enzyme, allowing a hydrogen bond between the main-chain amide of residue Trp141 and the carboxylate o

31 Main-chain amide relaxation of CTD-SP-NC was measured in

32 h known Raman tensors for modes of the pVIII main chain (amide I) and Trp and Tyr side chains to reve

33 's side chain carboxylates and the protein's main chain amides.

34 ive site, was bound by hydrogen bonds to two main-chain amides and to two basic residues, H129 and R1

35 NaAD are recognized by interaction with the main-chain amides of Thr85 and Tyr117, a positive helix

36 he motif, involving H-bond interactions with main-chain amides within the turn.

37 most of the SLC5 family, interacts with the main chain amino group of G444, capping the alpha-helix

38 base Glu(212) side chain interacts with the main chain amino group of P1 and P1'.

39 e apolar domain consists of a perfluorohexyl main chain and a butyl hydrogenated branch as a side cha

40 accommodated by local shifts of the protein main chain and by adoption of alternative side chain rot

41 binding to the MHC, repositions the peptide main chain and generates subtly enhanced interactions be

42 wo-dimensional (2D) pi-conjugation along the main chain and in the lateral direction, leading to high

43 attention to the general orientation of the main chain and mutual spatial arrangement of secondary s

44 re linked by hydrogen bonds between both the main chain and side chain amides, and side chains point

45 For CaM-L7 bound to C28W, main chain and side chain chemical shift perturbations i

46 This is most likely due to the fact that the main chain and side chain of Asp46 form a characteristic

47 a water molecule hydrogen bonded between its main chain and side-chain oxygen atoms.

48 affold with repeating S = 1/2 centers in the main chain and suggest antiferromagnetic interactions be

49 onformations differ via a translation of the main chain and the corresponding side chains in the 5- t

50 ortant interactions between the PTS1 peptide main chain and up to five invariant Asn side chains of P

51 drical copolypeptide brushes, where both the main chains and side chains can be prepared with control

52 eals sinefungin-specific polar contacts with main-chain and side-chain atoms that can explain the 3-f

53 l are largely consistent with alterations in main-chain and side-chain conformational entropy.

54 Both binding events lead to perturbation of main-chain and side-chain dynamics at sites distal to th

55 e modulated by molecular manipulation of the main-chain and side-chain isomeric structures.

56 t rely on arrays of basic residues; instead, main-chain and side-chain nitrogen atoms and two calcium

57 ctural metamorphosis conserves the number of main-chain and side-chain to main-chain hydrogen bonds a

58 These temporal (main chain) and triggered (side chain) degradation proce

59 of tacticity, heavy atom substitution on the main chain, and chain helicity on the depolarization beh

60 alpha analogues with a modified N-methylated main chain at position 2, 3, or 5 retain significant CXC

61 side chains interact mostly with the epitope main chain atoms and side-chain carbons.

62 serine residues form hydrogen bonds with the main chain atoms of gp120.

63 nformation regarding the displacement of the main chain atoms that form the oxyanion hole and movemen

64 bond cysteines coordinating the AMP with its main chain atoms, a nucleotide-binding motif that appear

65 edicted and measured structures is 3.9 A for main chain atoms.

66 de, in this structure MP(58-66) exposes only main chain atoms.

67 in atoms preferably form hydrogen bonds with main chain atoms.

68 alogs show very similar interactions for the main-chain atoms and the conserved P1 Asp and P4 Asp, wh

69 actions while water molecules cross-link the main-chain atoms of alpha-synuclein to atoms of NbSyn2,

70 4017 forms hydrogen bonds with the conserved main-chain atoms of Asp29 and Asp30 of the protease.

71 rahydrofuranyl urethane moiety of TMC114 and main-chain atoms of D29 and D30.

72 A) showed differences in the position of the main-chain atoms of residue 82 compared to PR structure

73 ecognition is substantially mediated through main-chain atoms of the amino acid.

74 positions form at least one hydrogen bond to main-chain atoms that are not involved in hydrogen bonds

75 through formation of a beta-zipper involving main-chain atoms, burying an important hydrophobic surfa

76 As OPUS-PSP excludes interactions among main-chain atoms, its success highlights the crucial imp

77 ween the di-mannose ligand and predominantly main-chain atoms.

78 or complexes of PR1 with an RMSD of 1.1 A on main-chain atoms.

79 an-square (CRMS) in the transmembrane region main-chain atoms.

80 are not involved in hydrogen bonds to other main-chain atoms.

81 rotates approximately 180 degrees about the main chain axis, requiring surrounding side chains to re

82 In addition, the removal of side-chain/main-chain backbonding distorts the helix, which alters

83 estigated the impact of threonine side-chain/main-chain backbonding on the backbone dynamics of the a

84 erchain interaction only through the protein main chain, beta-carbon, or associated hydrogen atoms.

85 is and characterization of a novel series of main-chain boron-containing conjugated polymers (CPs), b

86 BPAs), which represent the first examples of main-chain boron-containing CPs without aromatic moietie

87 es (AXOS) having 2-10 xylose residues in the main chain but no unsubstituted xylooligosaccharides (XO

88 Thus, preorganization of a main chain by subtle changes to side chains can confer e

89 a methyl group at the beta carbon along the main chain can drastically affect selectivity, but its i

90 The main chain carbonyl group of His-161, Arg-300, and Lys-3

91 teractions of Arg130, Glu86, Arg135, and the main chain carbonyl groups of Cys132 and Leu55 appears t

92 sed tendency for the electron density of the main chain carbonyl groups within alpha-helices to be po

93 otassium ion is directly coordinated by five main chain carbonyl groups, and we show this site is ess

94 This position was suggestive because its main chain carbonyl is within hydrogen-bonding distance

95 de chains of Asp123, Glu136, His146, and the main chain carbonyl of Ile137.

96 en the phenolic hydroxide of the SHA and the main chain carbonyl of Pro132, between the carbonyl oxyg

97 new hydrogen-bonding interaction between the main chain carbonyl of the P(5) residue and the main cha

98 rboxylate groups of Asp55 and Glu65, and the main chain carbonyl of Thr66.

99 Both structures show a main chain carbonyl oxygen closer to the active site ser

100 e hPNMT active site has been identified, the main chain carbonyl oxygen of Asn39.

101 e SAM headgroup (H(3)C- and/or HO-) near the main chain carbonyl oxygen of Cys153 and that Phe88 (ana

102 ne (TM) alpha-helix 2, hydrogen bonds to the main chain carbonyl oxygen of Ile-259 on TM alpha-helix

103 We have surveyed the bridging of pairs of main chain carbonyl oxygens by cations or by delta(+) hy

104 hored by halogen bonding of an iodine with a main-chain carbonyl and (ii) an acetylene linker, enabli

105 When the activated asparagine attacks its main-chain carbonyl carbon, the resulting oxyanion is st

106 sidechains, a water molecule, a serine and a main-chain carbonyl in the unwound stretch of trans-memb

107 no moiety participates in three H-bonds: two main-chain carbonyl oxygen atoms (from R194 itself and f

108 t to the intracellular side, is made of four main-chain carbonyl oxygen atoms and four threonine side

109 extracellular side, are made of exclusively main-chain carbonyl oxygen atoms.

110 g of both inhibitors that interacts with the main-chain carbonyl oxygen of Tyr188.

111 participates in Ca(2+) coordination with its main-chain carbonyl oxygen, and this function is not exp

112 These macromolecules can be transformed into main-chain cationic polymers upon quaternization of the

113 ried Ser238 side-chain hydrogen bonds to the main-chain CO of Asn170 on the Omega loop, that is unalt

114 s--Textal, Resolve and ARP/WARP--in terms of main chain completeness, sidechain identification and cr

115 which share common features: (i) a galactan main chain composed of two 1-->3 beta-linked trigalactos

116 ree of branching, and monosaccharide residue main chain composition.

117 e biosynthesis is initiated by a spontaneous main-chain condensation reaction.

118 set of PDZ domains bind peptides with a bent main-chain conformation and the specificities of these n

119 dicted side-chain packing interactions and a main-chain conformation indistinguishable from the wild-

120 The rigid-rod main-chain conformation of these polymers drastically lo

121 domains, but the C(alpha) domain exhibits a main-chain conformation remarkably different from those

122 A comparison of IBP and IBP(c) main-chain conformation reveals the flexible nature of t

123 simulation has not only reached the correct main-chain conformation, but also a very high degree of

124 These involve discrete changes in main-chain conformation, expanding the site; few continu

125 AP-1 appears to be facilitated by a strained main-chain conformation, which suggests a potential role

126 facilitate domoate binding by affecting the main-chain conformation.

127 y toward Ins(1,2,4,5,6)P5 These features are main-chain conformational differences in loops adjacent

128 sequence diversity, length variability, and main-chain conformational plasticity.

129 Main-chain conformational restraint was applied to facil

130 ed in the structure, and there are alternate main chain conformations for the magnesium positioning l

131 Atypical main-chain conformations can help identify strains withi

132 2.0-A-resolution structure reveals canonical main-chain conformations for the V(alpha), V(beta), and

133 Two of the four helices have alternate main-chain conformations that differ by a 1.3-1.7A shift

134 ems, the effects of fluorine substitution on main-chain conformations, packing, and electronic coupli

135 in a pocket on the proteasome surface using main chain contacts of its C-terminal residues and uses

136 protein (GFP) is triggered by a spontaneous main chain cyclization reaction of residues 65-67.

137 reactive sites, low toxicity, and controlled main-chain degradability has not been realized, yet this

138 t intermolecular interactions induced by the main-chain deuteration are shown to change the film crys

139 ity and fit of predicted and observed [/psi] main chain dihedral angle propensities.

140 ty and fit of predicted and observed phi/psi main chain dihedral angle propensities.

141 tereoelectronic effects that preorganize the main-chain dihedral angles in the conformation found in

142 structure are particularly sensitive to the main-chain disrupting effects of Pro replacements.

143 o the suggestion that amyloid is a primitive main chain-dominated structure.

144 The main chain dynamics of calmodulin are found to be largel

145 drogen bond, apparently caused by changes in main chain dynamics, provide a mechanism for the long di

146 ns from molecular dynamics indicate that the main-chain dynamics of the protein show little variation

147 toconvertible class of FPs, a light-mediated main chain elimination reaction partakes in the formatio

148 olysaccharides and not the more recalcitrant main chains, especially cellulose.

149 e helix with insignificant deviations to its main chain, even though 2/3 of the residues are nonnatur

150 o Pro in order to test the impact of reduced main chain flexibility at the putative hinge position.

151 r, its encagement in a native assembly damps main-chain fluctuations.

152 computing the Shannon entropy of the protein main-chain fluctuations.

153 tiation and control of the polymerization of main chain fluorinated monomers as exemplified by vinyli

154 The main chain fold of G311 can be superimposed on the wild-

155 The main-chain fold of the enzyme belongs to the (beta/alpha

156 25; alpha7, M131-E141) that adopt an overall main-chain fold similar to that of PBPs found in Anthera

157 ts indicate that the mutant has very similar main chain folding compared to wild-type.

158 philic polymer with cleavable side chain and main chain functional groups has been designed and synth

159 N-alkyl alpha-bisimines were employed as main-chain functional groups in acyclic diene metathesis

160 nd relatively tolerant of alterations to the main-chain functional groups in order to achieve this sp

161 ituted proline amino acids, with the peptide main chain functioning to "protect" the proline amino an

162 the active site hydrogen-bonding network and main-chain geometry at Asp120, a key component of the bi

163 Thus, the force does not directly break the main chain H-bonds: it destabilizes them in such a way t

164 Recent studies suggest the dominant role of main-chain H-bond formation in specifying beta-sheet top

165 f the design and supported the importance of main-chain H-bonds in determining beta-sheet topology.

166 y linking the side-chain protons to proximal main-chain HNs via bipartite graph matching.

167 due to effects of local sequence sterics and main-chain hydration on the persistence length of the ch

168 re extended than previously suspected due to main-chain hydration or local sterics.

169 the hydration interaction of the hydrophobic main-chain hydrocarbons.

170 ine residue in the hinge removes a conserved main chain hydrogen bond donor.

171 a strands that is centered near a bifurcated main chain hydrogen bond interaction between these two s

172 ha-helix in which the N-terminal i and i + 4 main chain hydrogen bond is replaced with a carbon-carbo

173 ses have a cross beta-sheet structure, where main chain hydrogen bonding occurs between beta-strands

174 rils have a cross-beta-sheet structure where main chain hydrogen bonding occurs between beta-strands

175 The main chain hydrogen bonding pattern in parallel beta-she

176 All NESs also participate in main chain hydrogen bonding with human CRM1 Lys568 side

177 air, only one of the residues is involved in main chain hydrogen bonding with the strand containing t

178 accommodate a wide range of residues, while main chain hydrogen bonds may help dictate substrate-bin

179 I, and the G440A mutation, which abolishes a main-chain hydrogen bond associated with the interaction

180 ificial alpha-helices in which an N-terminal main-chain hydrogen bond is replaced by a carbon-carbon

181 ge in place of the characteristic N-terminal main-chain hydrogen bond of canonical helices.

182 polyglutamine beta-strands are stabilized by main-chain hydrogen bonding.

183 s the number of main-chain and side-chain to main-chain hydrogen bonds and the number of fully buried

184 enthalpic barriers by eliminating inhibitory main-chain hydrogen bonds in the precursor state.

185 hydrophobic interactions while cross-strand main-chain hydrogen bonds manifested the ordered oligome

186 d an NMR-based site-specific analysis of the main-chain hydrogen bonds that stabilize its native conf

187 Up to four main-chain hydrogen bonds to the inhibitor also appear s

188 An antiparallel beta-sheet with six main-chain hydrogen bonds was dominant in the implicit s

189 er with a two-residue register shift and six main-chain hydrogen bonds.

190 formed by the beta-sheet extension along the main-chain hydrogen-bond direction, whereas the other ha

191 s for the generation of all the chirality of main chain hydroxyaldehyde, while the appended side-chai

192 ed by replacing an N-terminal intramolecular main chain i and i + 5 hydrogen bond with a carbon-carbo

193 lated rhamnose as the capping residue of the main chain, (ii) a hyperbranched fucose unit, and (iii)

194 s mainly from the exceptional ability of the main chain in a structurally relaxed beta-conformation t

195 e, hydroxyl, and aldehyde to the polysulfone main chain in excellent conversion.

196 egy, we show that complete assignment of the main chain (including prolyl residues) can be achieved w

197 Deletion mapping indicates that main chain interaction(s) of residues 182-186 of SNAP25

198 glutamate, confirming the importance of this main-chain interaction in GluR6.

199 that amyloid formation arises primarily from main chain interactions that are, in some environments,

200 ADP is tightly bound through side-chain and main-chain interactions, whereas at the other two sites

201 and S3) the ADP molecules are only bound by main-chain interactions.

202 t these contacts involve both side-chain and main-chain interactions.

203 Degradation of the main chain is shown to cause morphology of the supramole

204 The Frq1 main chain is similar to that in free Frq1 and related p

205 particles, of controlled diameter, made from main-chain liquid crystalline polymers using a mini-emul

206 mposed of d(5)-vanadium metal centers in the main chain, making it a rare example of a spin-carrying

207 n its native state, the coupling between the main-chain (MC) motions [represented by coarse-grained d

208 cting the controlled synthesis of high order main-chain mechanically interlocked polymers.

209 The prevalence of non-specific main chain-mediated interactions demonstrates that poten

210 s a function of temperature reveals that the main chain melting transition and the lamellar-to-invert

211 migration insertion polymerization (MIP) for main chain metal-containing polymer (MCP) synthesis.

212 ar dynamics simulations focused on measuring main-chain movement.

213 ow that when the H-bonding capability of the main-chain N-H of the conserved glutamine is eliminated

214 rovided the highest affinity at pY+1 and its main chain NH is involved with a hydrogen bond with Stat

215 scribed in the accompanying paper, where the main-chain NH groups point inwards relative to the ring

216 catalysis, such as a hydrogen bond between a main chain nitrogen atom and the flavin redox center (N5

217 te to form hydrogen bond interactions to the main chain nitrogen atoms of Cys356 and Leu314, and hydr

218 site contains an oxyanion hole formed by the main chain nitrogen atoms of Thr-80 and Phe-79 and the s

219 talytic cysteine is covalently linked to the main chain nitrogen of an adjacent residue.

220 cies, in which tryptophan cross-links to the main chain nitrogen of the adjacent glycine residue to f

221 le in active Site B the 2-nitro contacts the main chain nitrogen of Thr41 and the 4-nitro group the L

222 ol oxidase has revealed an unusual elongated main chain nitrogen to hydrogen bond distance positionin

223 the side-chain oxygen atom of Asp169 and the main-chain nitrogen of Arg112 binds together the incomin

224 Here we present main-chain nitrogen-15 relaxation measurements for the u

225 ized through measurement of enzyme kinetics, main chain NMR relaxation, X-ray crystallographic studie

226 e bound DRV lacks one hydrogen bond with the main chain of Asp30 in PR(L76V) relative to PR, possibly

227 lose, especially xylan that is composed of a main chain of beta-1,4-linked xylopyranoside residues de

228 hich are repeated every fifth residue in the main chain of ELPs.

229 The insertion of trisubstituted ureas in the main chain of N,N'-linked oligourea foldamers locally im

230 med intrinsic localized modes (ILMs), of the main chain of proteins based on all-atom molecular dynam

231 the E-dimer interface, including the exposed main chain of the E fusion loop and the two conserved gl

232 al change requires modest adjustments to the main chain of the heme crevice loop and is facilitated b

233 The main chain of the lipid is installed via a highly stereo

234 the hydrogen-bonding network provided by the main chain of the protein scaffold.

235 roduction of inhibitor interactions with the main chains of key amino acids and seeking a unique inhi

236 ackbone by side chains of D109 and Y113; and main chains of P81 and W112.

237 een JMJD2A and peptides largely involves the main chains of the enzyme and the peptide.

238 ionalities are orthogonally connected to the main chains of the respective polymers have been synthes

239 The main-chain of the peptide is well defined and makes a se

240 ell-established, readily accessible class of main chain organosilicon metallopolymer consisting of al

241 Our main-chain orthogonal assembly approach allows the engin

242 The main-chain oxygen atoms, which were exposed to the pore

243 bromine atoms makes polar contacts either to main chain oxygens in the hinge region of the kinase or

244 anscription factor is due in large part to a main-chain perturbation rather than to specific features

245 polypeptides where successive residues have main-chain phi,psi conformations of opposite hand.

246 Here, we compare the distributions of main chain (Phi,Psi) angles (i.e., Ramachandran maps) of

247 oactuation within the local structure of the main chain polymer results in a mechanically controlled

248 tives with a poly(vinyl alcohol)MW27kD (PVA) main-chain polymer bearing poly(ethylene glycol)MW2000 (

249 o afford a linear, mechanically interlocked, main-chain polymer.

250 Here we report the synthesis of metalated main-chain polypseudorotaxanes via ring-opening olefin m

251 contrast, foldamers with aryl rings in their main chains possess distinct conformations that may give

252 3S-Flp), like 4S-Flp, should preorganize the main chain properly for triple-helix formation but witho

253 ater flexibility that glycine confers on the main-chain provides no advantage in terms of the persist

254 gesting that both side-chain disordering and main-chain rearrangement play important roles in alterin

255 d and ADP-bound forms, involving significant main-chain rearrangement.

256 Arg141, but also requires substantial local main chain rearrangements relative to the structurally h

257 dy of this article is focused on a series of main chain redox and beta-elimination reactions mediated

258 -vis spectra demonstrate that the conjugated main chains remain essentially planar through the alpha

259 ng the primary monomer sequence of a polymer main chain represents a considerable challenge in polyme

260 brillar LCs involves an inducible N-terminal main chain reversal that results in the formation of a p

261 ucture comprises two beta-grasp folds having main chain root mean square deviation (r.m.s.d.) values

262 due loops in the PLOP benchmark, the average main-chain root mean square deviation of the best scored

263 ng that of NMR native structure to within 1A main-chain root mean square deviation.

264 ures are similar to those of native insulin (main-chain root-mean-square deviations (RMSD) of 0.45 an

265 al residues in Elk have significantly higher main-chain root-mean-square deviations than their counte

266 activated mechanophore that does not lead to main chain scission and an elastomeric polyurethane enab

267 ater ability to depth profile due to ease of main chain scission.

268 onversions of polymers comprising pendant or main-chain secondary amines were observed for an array o

269 hs provide an unbiased method for evaluating main-chain segmental motions; they resolve an apparent d

270 arrangements but also showed movement of the main chain segments that are contiguous with the mutatio

271 cyclic ether groups with a stiff polycyclic main chain, serves as a grafted polymer skin on the Li m

272 te a highly strained disulfide and localized main chain structural changes that presumably account fo

273 The main chain structure of the central domain in solution a

274 The overall main chain structure resembles an immunoglobulin variabl

275 The PASs have a previously unreported main chain structure that is composed of pyranose rings

276 The overall main-chain structure of recoverin in the complex is simi

277 The main-chain structures are first constructed from initial

278 Whereas respective T- and R-state main-chain structures are similar to those of native ins

279 oiding tedious modification of side-chain or main-chain structures.

280 This contribution introduces main-chain supramolecular ABC and ABB'A block copolymers

281 een side-chain fluorinated benzyl esters and main-chain terminal arenes, in turn controlling the conf

282 In contrast to the main chain, the motions of the methyl-bearing side chain

283 chains and connected with the donors on the main chain through an efficient pi-bridge.

284 ent: (1) as suggested by informatic studies, main-chain to base hydrogen bonding makes up an importan

285 moiety and the carbonyl of hyp distorts the main-chain torsion angles that typically accompany a C(g

286 oelectronic and steric effects that restrict main-chain torsion angles.

287 n rotation is accompanied by a change in the main chain torsional angles of Asp402, a conserved resid

288 c, much larger than is typically seen in the main chain transition at these anesthetic concentrations

289 It produces, for the system above the main chain transition of the saturated lipid, phase diag

290 of disulfide bonds' rich proteins with intra main-chain triazole links.

291 and a Gal 6-linked to Gal-1 and Gal-2 of the main-chain trigalactosyl repeats; (iii) a common side ch

292 er with NHCs orthogonally positioned along a main chain upon generation in situ.

293 (i.e., molecular muscles) can be linked into main-chain Upy-based supramolecular polymers.

294 zes the proper docking of the Ile(181) (P1') main chain, whereas the hydrophobic pockets stabilize th

295 ty destroys or recovers the curvature of the main chain, which demonstrates external control over the

296 train of the substituted ketal groups in the main chain, while for polymers with linear (acyclic) ket

297 n structure calculations revealed a galactan main chain with a reverse turn involving the beta-1-->6

298 nsisting of a 1,4-linked beta-mannopyranosyl main chain with branch decorations.

299 ins for solubility, that alternate along the main chain with electron-rich aromatic segments comprisi

300 n to sugar precursors requires the action of main chain xylanases as well as alpha-glucuronidases tha