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1 ffering) or generally throughout daily life (main effects).
2                         Gender modified this main effect.
3 , possibly due to the small magnitude of the main effect.
4 in magnitude were greater than environmental main effect.
5 tions can have important implications beyond main effects.
6 fication of important G x E interactions and main effects.
7 orphisms, not just those showing significant main effects.
8 ne association approach used to test genetic main effects.
9 for estimating the genetic and environmental main effects.
10 ions and correlation patterns in addition to main effects.
11 ey tended to be small compared with stimulus main effects.
12 pproach could detect epistatic QTL with weak main effects.
13 d on whether or not the loci have individual main effects.
14 uality measure that balances interaction and main effects.
15 ed only for pairs of loci of which both have main effects.
16 onic SNP exhibited statistically significant main effects.
17 by-DAR interactions partially counteract the main effects.
18 erformed using maternal and paternal PTSD as main effects.
19 ) or are proportional to respective exposure main effects (a variant of Tukey's one-degree test).
20                 5g.L(-1) lecithin showed its main effects after 16days of storage: highest SSC, highe
21                 1g.L(-1) lecithin showed its main effects after 8days of storage by reduction in tota
22                10g.L(-1) lecithin showed its main effects after 8days of storage with highest SSC, ch
23                                              Main effects analysis of sensory experience revealed les
24                                           By main effects analysis, peak VO2 was increased significan
25 plication of this method illustrates mapping main effect and interacting QTLs for heading time in the
26 etween pairs of SNPs providing evidence of a main effect and observed 17 significant interactions (16
27 10(-8)) loci by using joint tests of the SNP main effect and SNP-age interaction.
28             Eight markers showed significant main effects and 18 markers showed significant Q x E int
29 netic values while incorporating both marker main effects and epistatic effects.
30 trol and analytical procedures for measuring main effects and for evaluating environmental exposure m
31 thors also compared 2 joint tests of genetic main effects and G-E interaction.
32 oss males, both in terms of the magnitude of main effects and in the epistatic interactions.
33     Thus, we find positive evidence for both main effects and interaction between genetic loci and de
34 puting platform that can systematically scan main effects and interaction effects among all possible
35                               Joint tests of main effects and interactions are performed conditional
36                                              Main effects and interactions between lifetime asthma, a
37 peated-measures design allowed assessment of main effects and interactions of light level, viewing co
38                        Interpretation of the main effects and interactions subsequently enables the s
39 sition at 6 and 24 mo were obtained for gene main effects and interactions with a low-fat diet (20% f
40 to test single-nucleotide polymorphism (SNP) main effects and SNP x education interaction effects on
41                       On simulated data with main effects and statistical interactions, we compare ac
42       On average, the sum of all significant main effects and the sum of all significant epistatic ef
43                      We used global tests of main effects and treatment interactions, adjusting the P
44 can that may have been conducted for genetic main effects, and thus has the potential to uncover new
45 els slightly overestimate genetic variances, main effects are assessed accurately and precisely.
46                                          Two main effects are proposed to explain biodiversity-ecosys
47                                          The main effects are represented by the means of QTL effects
48 ar, quadratic, and cubic BSA terms and a sex main effect as independent variables.
49 esearch in Transplantation Network to detect main effect association signals across regions such as t
50 ypic association results, EMDR confirmed the main effect at RS1912960 (in GABRA4).
51  cold storage and subsequent shelf life, the main effect being observed for those fruits coated with
52                Analyses of variance revealed main effects, but not an interaction, for apolipoprotein
53 ility loci that, on their own, have marginal main effects by use of gene-gene interaction tests have
54                                A significant main effect comparing the two groups (F (1, 43)=21.90, p
55 hat responded to soil drying and hundreds of main-effect eQTLs.
56                          For most scenarios, main-effect estimates for cadmium and lead with increasi
57                                          The main effects examined were microbiological sputum conver
58 LHF total score with exercise and with diet (main effect: exercise, -1 unit [95% CI, -8 to 5], P = .7
59 dy Short Form 36 Physical Component Summary) main effect: F(1, 172) = 9.87, P < 0.01].
60 R-E group than for the NR-E group (treatment main effect: F1,68 = 5.4, P = .02, d = 0.50, and Delta =
61 r than stage-wise strategies (i.e. selecting main effects first, and interactions second, from those
62  balance scores were different, with a large main effect for age and a small effect for sex.
63 analysis showed that there was a significant main effect for DHT exposure, but not for genotype, indi
64                  There is some evidence of a main effect for genotype and some evidence for a gene by
65 ificant in the women (P < 0.05); there was a main effect for method but not race-ethnicity.
66                                  There was a main effect for site but not for treatment condition.
67 89, p<0.001, Partial Eta Squared=0.57) and a main effect for time (F (2, 43)=3.76, p=0.03, Partial Et
68  (CON group) and by 10% +/- 10% (LEU group) (main effect for time, P < 0.05), but no differences betw
69 d haplotypes and risk of NHL, as well as the main effects for all independent SNPs from a gene in mul
70 yes method that simultaneously estimates 127 main effects for all markers and 127(127-1)/2=8001 inter
71                        One can also estimate main effects for exposures and now flexibly assess model
72  population-based controls are not included, main effects for exposures cannot be estimated, and cons
73                Findings revealed significant main effects for individual and neighborhood predictors
74 miodarone was tested using a Cox model, with main effects for randomized treatment and amiodarone and
75                             Results revealed main effects for the executive attention and orienting n
76 rtional odds logistic regression model, with main effects for three readers, two techniques, and four
77                                              Main effects for understanding were found for processabi
78                                          The main effects found were that explicitness and reassuranc
79  statistically significant associations from main-effect genome-wide association studies may be more
80 ffects are more frequent and larger than the main effects: half of the interactions explained >20% of
81 mong patients treated with aprotinin, with a main-effects hazard ratio for death of 1.32 (95% confide
82 % CI, 0.96-1.45; P = 0.12; lutein/zeaxanthin main effect HR, 1.04; 95% CI, 0.85-1.28; P = 0.71).
83 significantly different (omega-3 fatty acids main effect HR, 1.18; 95% CI, 0.96-1.45; P = 0.12; lutei
84                    These results support the main effects hypothesis and indicate that hypothalamic-p
85  all relevant data to examine evidence for a main effect (i.e., the effect in a model that does not i
86 mary objective in inference, rather than the main effect in a model with gene-environment interaction
87 affirm transition state stabilization as the main effect in enhancing chemical rates and provide a un
88 al divergence of Scr roles during embryonic (main effect in labium) and post-embryonic (main effect i
89  (main effect in labium) and post-embryonic (main effect in prothorax) development.
90                However, phonological priming main effects in both the N2 and P3 ranges were indisting
91 ased on random regression analysis, revealed main effects in favor of FBT on all measures of eating p
92      Results also revealed significant group main effects in the amygdala and insula bilaterally, ref
93      Latinos exhibited significant haplotype main effects in two blocks even after adjusting for admi
94 ots for SNPs in ALOX5AP, TNF, and KCNJ11 for main effects; in LPL and TUB for glycemic index interact
95                        Lower prices have two main effects: increasing overall energy consumption, and
96 high computational cost, do not respect the "main effect, interaction" hierarchical structure, or use
97        Regression modeling refined the Chr 4 main effect into an approximately 50-cM region with thre
98                                 Instead, the main effect is seen in legs.
99 ifies their behavior to varying extents, its main effect is to regulate the function of AMPAR subunit
100 ns, especially when the marginal strength of main effects is weak.
101                           Locomotion had two main effects: it increased spontaneous activity, and it
102 dy tissues triggered by DvSnf7 RNAi were the main effects leading to the death of WCR.
103                     We report 58 significant main effect loci and 24 significant epistatic interactio
104         The PS is frequently estimated using main-effects logistic regression.
105                               Fully adjusted main effect models resulted in hazard ratios of 1.01 (95
106 en BC and blood markers were not observed in main effects models or when stratified by obesity status
107                            Synergism was the main effect observed among the tested mixtures, mainly f
108                                          The main effects observed were lowering of total blood lipid
109                                        IL-6 (main effect odds ratio [OR] 1.72; 95% confidence interva
110                                           No main effect of ACEs on average BP levels was found.
111                                  There was a main effect of ADM over CBT on the HAM-D (beta = -0.88;
112                                  There was a main effect of adversity but not of monoamine oxidase A
113 olume-corrected [(11)C]PBR28 data revealed a main effect of alcohol dependence (P=0.034), correspondi
114  In a subsample of normal controls, both the main effect of amyloid deposition of worse memory perfor
115                                We observed a main effect of anxiety levels on fullness and bloating (
116                     By either mechanism, the main effect of both MTAs is to effectively stabilize the
117                      There was a significant main effect of breakfast condition (P = 0.04) on total d
118                     There was no significant main effect of breakfast condition on energy intake at l
119              Kinetic experiments show that a main effect of BRICHOS is to prolong the lag time in a c
120                                      Thus, a main effect of Ca(2+) on E-Syt1 is to reverse an autoinh
121                                A significant main effect of calorie (high compared with low; P < 0.00
122                      There was a significant main effect of castration and social context.
123 production in the liver, we suggest that the main effect of central insulin on hepatic glucose metabo
124                                          The main effect of circadian misalignment, either phase adva
125             Although there was no beneficial main effect of citalopram, it reduced Stop-Signal Reacti
126                       The results revealed a main effect of COMT genotype in the ventral striatum and
127 f distribution values revealed a significant main effect of condition (SHS vs control) (F(1,22) = 42.
128 om the unaffected limb [PSS = -18 +/- 13 ms; main effect of condition F (1, 9) = 98.6, P < 0.001].
129 rror rate that the authors observed when the main effect of continuous body mass index was misspecifi
130 f distress and coping revealed a significant main effect of coping (OR = 0.7 [95% CI = 0.7-0.8]), but
131                                          The main effect of DAT1 genotype was seen in robust blood-ox
132              During successful inhibition, a main effect of diagnosis emerged in the right nucleus ac
133          In both the PET and fMRI studies, a main effect of diagnosis was observed, with PMDD patient
134 s a repeated measure indicated a significant main effect of diagnosis, F(1,24)=8.38, P=0.008, with si
135              Analysis of covariance showed a main effect of diagnostic group, with the CHR group show
136            Time to dropout had a significant main effect of dose, with mean time to dropout of 27, 36
137                      There was a significant main effect of encoding, showing superior recall perform
138 ed over the ensuing year, such that only the main effect of fire was evident after 16 months.
139                                            A main effect of genotype was observed in the DLPFC and hi
140                                          The main effect of genotype was significantly greater activa
141 y significant activation associated with the main effect of group for the comparison of correct no-go
142                                            A main effect of group revealed elevated response in the m
143                                 There was no main effect of group status on thalamic volume and no si
144  that missing urine samples were positive, a main effect of group was not found for any drugs tested
145                                            A main effect of group, distinguishing cocaine from sucros
146 ive supranuclear palsy relative to controls [main effect of group, F(2,41) = 17.5, P < 0.0001; region
147 ression analysis was applied to test for the main effect of HapA and its interaction with dietary pro
148                                   We found a main effect of haplotype on ADRB2 density (P = 0.03) wit
149      In the mental stress trial, there was a main effect of haplotype on cardiac output (P = 0.04), a
150      There was partial evidence to suggest a main effect of haplotype on the change in SVR (P = 0.06)
151          There was a decreasing trend in the main effect of heat on childhood diarrhea in Brisbane ac
152                                    While the main effect of hepatitis C virus (HCV) is hepatitis, HCV
153 for age of onset and hyperglycemia exposure (main effect of hypoglycemia category, F [2,88] = 6.4, P
154                                          The main effect of IL-7 was an expansion of effector memory
155 ls based on these results suggested that the main effect of increasing odor concentration was to recr
156         Repeated-measures ANOVAs indicated a main effect of intensity for both anodal and cathodal tD
157 linear mixed model was used to determine the main effect of interventions and interaction term to ass
158                   Our results argue that the main effect of intramolecular disulfide bond formation i
159                                          The main effect of LA addition is that it allows performing
160 on, a 1-factor ANOVA was run to discover any main effect of lifestyle.
161  weight that are similar in magnitude to the main effect of litter size on weight.
162                      There was a significant main effect of LoR in the frequencies of 0.073-0.198 Hz
163            Post hoc analyses also revealed a main effect of MAOA genotype on having a disposition tow
164                                         This main effect of maternal status suggests a general differ
165                            Collectively, the main effect of microcracks is not to slow down fracture
166                  Finally, while there was no main effect of number of optimal solution paths, this pa
167           Importantly, the activation of the main effect of pain and the nocebo effect spatially over
168                  The model predicts that the main effect of peg-IFN is to reduce HDV production/relea
169 a decreased independent of diet composition (main effect of phase, P < 0.01; between diets, P = NS).
170 lled experimental conditions, data support a main effect of prenatal nutrition on highly translatable
171 on in PTSD symptoms in all 4 groups, but the main effect of prolonged exposure therapy was not statis
172         There was a significant between-pair main effect of PTSD diagnosis (as determined in the comb
173                                            A main effect of reduced BOLD signal in bilateral occipita
174 In contrast, with fast-rate RSVP, we found a main effect of repetition that did not interact with sen
175      We used a twin model that allowed for a main effect of SES on intelligence, as well as a moderat
176 ight status, race, and meal instruction, the main effect of sex (P < 0.001) remained significant, but
177  gained weight during the study; there was a main effect of sex, but not BPA treatment on body weight
178                        The results showed no main effect of stimulus type on temporal discrimination
179                             Nevertheless, no main effect of stimulus type was found, on either proact
180 nt learning (session 2), though there was no main effect of stress on RPE.
181                                We observed a main effect of task on left vOT activity but not stimulu
182 ects of task in dorsal PAG and right LC; and main effect of temperature in RVM and a task x temperatu
183 ag non-linear model was used to quantify the main effect of temperature on emergency department visit
184    Moreover, on neuroimaging measures with a main effect of the AKT1 genotype, there was significant
185             There was also a dose-dependent, main effect of the epsilon2 allele (p<0.0001), suggestiv
186                                          The main effect of the exposure was a shift in the response
187                                           No main effect of the GABRA6 rs3219151 was detected, but in
188                               No significant main effect of the interventions emerged on cancer-speci
189     In comparison with the LC-CONV diet, the main effect of the LC-P-LGI diet was a greater decrease
190     The kinetic parameters indicate that the main effect of the mutation of Arg228 to lysine is on th
191                         The magnitude of the main effect of the SNP increased with increasing levels
192 a 2-factor analysis, there was a significant main effect of the TB (P < 0.0001) but not CC (P = 0.128
193         Furthermore, there was a significant main effect of the TB on increasing apolipoprotein A-I (
194 o be the skeletal subspaces that receive the main effect of the treatment.
195                             In contrast, the main effect of the V1300F mutation was a depolarizing sh
196             Repeated measures ANOVA showed a main effect of time-point (F = 4.59, df = 1, P = 0.035)
197 esidual mass decreased in both groups by 6% (main effect of time: P = 0.021), with no effect of alloc
198                                          The main effect of treatment did not reach conventional leve
199 nced by a lack of significant interaction or main effect of treatment during hemodialysis and in the
200 tes did not differ significantly either as a main effect of treatment or as an interaction with sever
201 57% +/- 0.11%/d; placebo, 1.48% +/- 0.08%/d; main effect of treatment: P < 0.001) and REX (pooled mea
202 .87% +/- 0.09%/d; placebo, 1.71 +/- 0.10%/d; main effect of treatment: P < 0.001) legs.
203                                 There was no main effect of vitamin D level on overall survival in th
204                                          The main effect of Y208T, Y208S, and Y208A mutations is to c
205  linear mixed-effects models to estimate the main effects of air pollutants and effect modification b
206                                There were no main effects of APOE genotype.
207                 Furthermore, the significant main effects of castration and social context were the r
208 analysis of variance was performed examining main effects of condition and group and group-by-conditi
209                                          The main effects of D treatment, but not of E treatment, on
210                  In the DLPFC, there were no main effects of diagnosis or gender on Glx/W or GABA/W.
211                                We tested the main effects of drug (placebo vs Nicorette gum) and time
212 ed, compared with that needed to demonstrate main effects of either genes or exposures.
213                                   There were main effects of FH (FH negative > FH positive) in the le
214                                              Main effects of genotype and diagnosis on activation and
215                                              Main effects of Group (p<0.005 height threshold, familyw
216                                  Significant main effects of Group (p<0.05) revealed decreased fALFF
217            In contrast, our findings for the main effects of life stressors (strong risk factor) and
218 are influenced by many factors including the main effects of many quantitative trait loci (QTLs), the
219 he rights of others (p < .05), there were no main effects of MAOA genotype, and MAOA genotype was not
220     Region-of-interest analyses indicated no main effects of medication or A118G genotype.
221                                    Thus, the main effects of metamorphosis on insect chemistry were l
222                                              Main effects of noxious thermal stimulation were observe
223 rge number of effects, including covariates, main effects of numerous loci, and gene-gene (epistasis)
224 ion that most genetic variance is due to the main effects of QTL.
225                                  The genetic main effects of QTLs, QE interaction effects and the cor
226                                              Main effects of sex were not detected.
227                While we revealed significant main effects of sex, there were no significant effects o
228                                              Main effects of smoking status and PTSD symptom severity
229                                              Main effects of smoking, snus, and the rs1051730 variant
230 r among all species and substrates, with few main effects of species or substrate observed throughout
231 the brainstem nuclei revealed the following: main effects of task in dorsal PAG and right LC; and mai
232                             The results show main effects of the COMT gene variant (P = .002), birth
233                 Univariate GLM exploring the main effects of the independent variables on physical an
234 rom extracellular ATP is responsible for the main effects of the latter in human cervical cancer cell
235                         Although none of the main effects of the loci were significant, estimated anc
236 ysis was used to compare BOLD activation for main effects of the PS, ED, and their interaction.
237                                There were no main effects of the SNPs on PTSD symptoms and no signifi
238 ion that can simultaneously capture both the main effects of the variants within a genomic region and
239 sis-generating observations suggest that the main effects of ticagrelor may not relate to the rapidit
240                                   There were main effects of time (indicating improvement across the
241                                  Significant main effects of time by group interaction for fractional
242                                          The main effects of time were observed in the total and subs
243 od and beverage intakes, we investigated the main effects of time, treatment, and the treatment-by-ti
244    Cox proportional hazards models showed no main effects of treatment (P=0.61) or AS (P=0.72) for ti
245                                          The main effects of treatment demonstrated no overall improv
246                          While there were no main effects of treatment, venlafaxine treatment was ass
247                                          The main effects of treatments and their interaction were as
248                          In this review, the main effects of vitamin E on enzymes involved in signal
249                    Somatization levels had a main effect on all 5 symptoms (P < .0001), independent o
250           Paternal depression did not have a main effect on any psychiatric disorder in adolescents a
251             We found that acute stress had a main effect on mtRNA expression and that expression of N
252      Conversion of Gly-336 to valine has its main effect on the Kd of serine binding to one form of t
253   Installation of information signage had no main effect on visitor attitudes or learning.
254                           CRF produced three main effects on dLGN stimulus evoked activity: (1) incre
255                            TPD did not exert main effects on mood or on task behavior, but affected b
256 ntrols, we found that rs3782206 genotype had main effects on the 1-back task (P=0.005), the 2-back ta
257 e, and physical properties of emulsions with main effects on their quality and stability.
258  The rs1344706 genotype produced significant main effects on total, frontal, and parietal lobe WM vol
259  interval [95% CI] 1.12, 2.66) and TNFalpha (main effect OR 1.49; 95% CI 1.16, 1.90) concentrations w
260       Each of the other markers had either a main effect or a Q x E interaction effect but not both.
261 the absence of a significant combat exposure main effect or diagnosis x exposure interaction.
262 rrespective of whether it is mostly due to a main effect or due to some interaction effect(s), via an
263 th time to a suicidal event and no treatment main effect or treatment x time interaction on suicidal
264 tivity index (SIT 56 +/- 15%, ET 29 +/- 12%; main effect P < 0.05).
265 ilt: 49 +/- 14 vs. 40 +/- 10 bursts min(-1); main effect, P < 0.05).
266 8.6 +/- 3.6 ml min(-1) (100 g)(-1)) men (age main effect, P = 0.001).
267 (-1); old men: 25.1 +/- 15.4 ml min(-1); age main effect, P = 0.77) as blood flow per unit mass of mu
268 pports conventional hypothesis tests for QTL main effect, pleiotropy, and QTL-by-environment interact
269                                              Main effect plots showed total FAAs extraction was favou
270 sent study, a heritability-adjusted genotype main effect plus genotype x environment (HA-GGE) biplot
271 e (ANOVA) and heritability adjusted-genotype main effect plus genotype-environment interaction (HA-GG
272                          In the first stage, main effect QTL are searched and mapped.
273                               The search for main effect QTL is robust and does not bias the search f
274                                   In all, 44 main effect QTL were detected above a 5% genome-wide sig
275                    We found that the largest main-effect QTL (single marker) and the largest epistati
276                  Thus by first mapping those main-effect QTL, the statistical power for the second an
277                                A total of 78 main-effect QTLs (M-QTLs) and 10 E-QTLs have been detect
278          This study identified a total of 78 main-effect QTLs (M-QTLs) with up to 42.33% phenotypic v
279 -age interactions only in whites but had DBP main effects replicated (p = 8.3 x 10(-4)) in 8,682 Asia
280 able logistic regression controlling for the main effects revealed that previous cardiac surgery, chr
281                                  Analysis of main effects revealed that training induced 33, 105 and
282 s first, and interactions second, from those main effects selected) in finding true interactions, esp
283 nt of Framingham risk score and DM, and such main effects significantly differed from controls (P = 0
284 on was primarily due to selection on genetic main effects tailored to temperature-dependent plasticit
285            Crystal structures revealed their main effect to be a weakening of interactions with the C
286       The linear model demonstrates that QTL main effects varied with DAR, and that some epistasis or
287                          At P7-15 the drug's main effect was behavioral depression; i.e., kittens, aw
288                           Parametrically, no main effect was found for TICV when predicting a dementi
289                  A statistically significant main effect was found for time (F1,198 = 75.92; P = .001
290                                          The main effect was observed in prothorax of Scr-RNAi adults
291 effects of group according to sex on GMV and main effects were analyzed throughout the whole brain by
292 .19 and OR, 0.55; 95% CI, 0.36-0.83], but no main effects were found among African-Americans.
293                          The qSD1 and qSD7-1 main effects were increased, while the qSD12 additive ef
294 ions were significant (P < 0.05) in the men; main effects were nonsignificant.
295 required analysis of 16 samples in which the main effects were not confounded by two-factor interacti
296                            Significant group main effects were observed for both response (odds ratio
297                            Within men, group main effects were observed involving these same regions,
298 d early degenerative mechanisms, because the main effects were seen at 7 d and lasted beyond the trea
299 be underestimated or even go undetected as a main effect when it is hidden in gene-by-environment (Gx
300 ction being driven by a significant genotype main effect (wildtype>heterozygote>null mutant).

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