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1 als, for which mAbs continue to serve as the mainstay.
2 mited growth rates as compared to industrial mainstays.
3 equences for the right heart are now seen as mainstay abnormalities that begin in the early stages of
4 as a promising future alternative to current mainstay acute and prophylactic treatment with plasma-de
5 tor (MOR, encoded by Oprm1) agonists are the mainstay analgesics for treating moderate to severe pain
6 oad application of the current SAH treatment mainstays, and re-examines agents previously failing cli
7                   Medical treatments are the mainstay approach to reduce the occurrence of angina and
8  is the primary target of beta-agonists, the mainstay asthma drugs.
9 s, we examined the dynamics of response to a mainstay chemotherapeutic, cisplatin, in multiple mouse
10 es to treat cancer into the consciousness of mainstay clinical research.
11                         RECENT FINDINGS: The mainstay definitions of high-risk nonmuscle invasive bla
12 options remain limited, with avoidance being mainstay, despite its adverse effects on quality of life
13                                          The mainstay for addressing conflicts of interest in health
14 alysis using array technology has become the mainstay for analysis of genomes and transcriptomes.
15                      While radiotherapy is a mainstay for cancer therapy, pneumonitis and fibrosis co
16 s of antibiotics that has been a therapeutic mainstay for decades.
17 storation of island habitats, SGARs remain a mainstay for eradication of invasive species.
18     Third-party software vendors provide the mainstay for integration of individual institutional EMR
19                                          The mainstay for intermolecular affinity and AsiA function a
20       Spine motility analysis has become the mainstay for investigating synaptic plasticity but is li
21                Platinum-based therapy is the mainstay for management of high-risk neuroblastoma.
22 ches, including biofeedback therapy, are the mainstay for managing these disorders; new minimally inv
23 ntel (PZQ), which has proved the therapeutic mainstay for over three decades of clinical use.
24       Oral anticoagulation (OAC) remains the mainstay for prevention of ischaemic stroke in atrial fi
25 om subjects with prior immunity has become a mainstay for rational structure-based, next-generation v
26                             The ELISA is the mainstay for sensitive and quantitative detection of pro
27 hnologies, omics experiments have become the mainstay for studying diverse biological effects on a ge
28                              Serology is the mainstay for syphilis diagnosis and treatment monitoring
29 though polymerase chain reaction remains the mainstay for the identification of viral pathogens.
30 umors, with PET and (18)F-FDG has become the mainstay for the imaging evaluation of several cancers.
31 ted genome editing of human cells becoming a mainstay for the investigation of human biology and dise
32                           Lithium has been a mainstay for the treatment of bipolar disorder, yet the
33 ugate tauroursodeoxycholic acid (TUDC), is a mainstay for the treatment of cholestatic liver disease.
34   Inhaled corticosteroids continue to be the mainstay for the treatment of mild and moderate asthma,
35                            They are also the mainstay for the treatment of minimal change nephropathy
36 rapamycin (mTOR) pathways continue to be the mainstay for treating metastatic RCC (mRCC).
37                               Surgery is the mainstay for treating postprostatectomy stress urinary i
38 inolones (e.g., ciprofloxacin) have become a mainstay for treating severe Salmonella infections in ad
39 aining artemisinins, 'ACTs', have become the mainstay for treating uncomplicated malaria in endemic c
40 vent of a pandemic, antiviral agents are the mainstay for treatment, but broadly neutralizing antibod
41 , and electrophysiological evaluation remain mainstays for the diagnosis of demyelinating inflammator
42 eric micro- and nanoparticles are becoming a mainstay in biomedicine, medical diagnostics, and therap
43 the circular scan centered on the ONH is the mainstay in both clinical and research analyses.
44 class of cancer drug, which continue to be a mainstay in breast cancer treatment.
45 onal tube culture systems have long been the mainstay in clinical virology for the growth and identif
46       Gene-expression profiling has become a mainstay in immunology, but subtle changes in gene netwo
47                        Beta-blockers are the mainstay in managing LQTS.
48 n emerging technology that may prove to be a mainstay in personalized gynecologic cancer care.
49       Central venous catheters have become a mainstay in the care of critically ill patients but, unf
50         Although glucocorticoids (GCs) are a mainstay in the clinical management of asthma, the targe
51 anidine ((123)I-MIBG) imaging is currently a mainstay in the evaluation of many neuroendocrine tumors
52                     (123)I-MIBG imaging is a mainstay in the evaluation of neuroblastoma, and (131)I-
53 lian target of rapamycin pathways remain the mainstay in the management of metastatic RCC.
54          Preoperative radiotherapy (RT) is a mainstay in the management of rectal cancer, a tumor cha
55          Surgical reconstruction remains the mainstay in the management.
56                       Metformin has become a mainstay in the modest therapeutic armamentarium for the
57                             Statins remain a mainstay in the prevention and treatment of atherosclero
58 d carbon-carbon bond-forming reactions are a mainstay in the synthesis of pharmaceutical agents.
59       Combination chemotherapies have been a mainstay in the treatment of disseminated malignancies f
60                        Thymectomy has been a mainstay in the treatment of myasthenia gravis, but ther
61            Myocardial revascularisation is a mainstay in the treatment of symptomatic patients or tho
62                          Patching has been a mainstay in treating unilateral congenital cataract.
63 etic derivatives of these hormones have been mainstays in the clinic for treating inflammatory diseas
64 ate numerous physiological processes and are mainstays in the treatment of inflammation, autoimmune d
65              Intravenous thrombolysis is the mainstay of acute ischemic stroke management for any pat
66 issue-type plasminogen activator remains the mainstay of acute stroke therapy within the initial 4.5
67            Although endocrine therapy is the mainstay of adjuvant treatment for ER+ breast cancer, th
68                The roundworm C. elegans is a mainstay of aging research due to its short lifespan and
69 nical assistance programs that have been the mainstay of agricultural water quality policy, alternati
70                                Currently the mainstay of anti-inflammatory therapy in respiratory dis
71                         Platinum drugs are a mainstay of anticancer chemotherapy.
72 s, polyenes and echinocandins constitute the mainstay of antifungal therapy for patients with life-th
73                         Aspirin is still the mainstay of antiplatelet therapy in the secondary preven
74 matory and bronchodilator treatments are the mainstay of asthma therapy and are used in a stepwise ap
75                      Glucocorticoids are the mainstay of asthma therapy.
76 a that is refractory to corticosteroids, the mainstay of asthma treatment.
77 of large numbers of compounds or siRNAs is a mainstay of both academic and pharmaceutical research.
78                            Radiotherapy is a mainstay of brain cancer treatment, but it causes signif
79 rugs targeting ERBB2 (HER2/NEU) signaling, a mainstay of breast cancer chemotherapy, cause dilated ca
80            While combination therapies are a mainstay of cancer chemotherapy, few studies have addres
81                     Proapoptotic drugs are a mainstay of cancer drug treatment.
82 rences between tumors and normal tissue is a mainstay of cancer research.
83 handful of tumor-derived cell lines form the mainstay of cancer therapeutic development, yielding dru
84          Although corticosteroids remain the mainstay of care for IOI, their use is fraught with comp
85                      Fluourouracil (FU) is a mainstay of chemotherapy, although toxicities are common
86    For centuries, opioid drugs have been the mainstay of chronic pain treatment.
87 a patient's risk of adverse events remains a mainstay of clinical care.
88             Quantitative PCR is a diagnostic mainstay of clinical virology, and accurate quantitation
89 oteins and other cellular components are the mainstay of conflicts across life forms.
90                            Radiotherapy is a mainstay of curative prostate cancer treatment, but risk
91                   Mercaptopurine (MP) is the mainstay of curative therapy for acute lymphoblastic leu
92 sure exerted by HIV-1 protease inhibitors, a mainstay of current anti-HIV-1 therapies, results in the
93 es, such as EGFR, ALK, ERBB2, and BRAF, is a mainstay of current cancer therapy but is hindered by in
94 t chains in monoclonal antibodies that are a mainstay of current drug pipelines.
95 etic stem cell transplantation (HSCT) is the mainstay of definitive treatment for children with a wid
96     The allergen challenge test has been the mainstay of diagnosis of allergic diseases for a long ti
97                                          The mainstay of diagnosis remains cystoscopy and transurethr
98 s mean that clinical assessment is still the mainstay of diagnosis.
99 stopathological examination is currently the mainstay of diagnosis.
100                                          The mainstay of diagnostic imaging is non-enhanced chest-com
101            For decades, culture has been the mainstay of diagnostic testing for bacterial enteric pat
102 f sulfadoxine-pyrimethamine (IPTp-SP) is the mainstay of efforts in sub-Saharan Africa to prevent pre
103 ual antiplatelet therapy (DAPT) has been the mainstay of efforts to prevent stent thrombosis.
104 the assessment of changes in tumour burden-a mainstay of evaluation of cancer therapeutics that provi
105                                          The mainstay of first-line treatment by professionals includ
106 he acid-suppressive medications that are the mainstay of GERD treatment.
107          Second, IFN-alpha, which has been a mainstay of HBV and HCV therapy over decades, and ribavi
108                     beta-Blockers (BB) are a mainstay of heart failure (HF) treatment, yet there are
109                                          The mainstay of hemochromatosis management is still removal
110         Whereas substitution of FVIII is the mainstay of hemophilia A therapy, treatment of patients
111  therapeutic antitoxin products that are the mainstay of human botulism treatment.
112 hibitors such as cyclosporin A (CsA) are the mainstay of immunosuppressive treatment for organ transp
113  Although intravenous immune globulin is the mainstay of initial treatment, the role for additional p
114                                          The mainstay of irAE treatment consists of immunosuppression
115                                          The mainstay of laboratory diagnosis for Lyme disease is two
116                       Blood cultures are the mainstay of laboratory diagnosis, but lack sensitivity d
117                        Statin therapy is the mainstay of lipid-lowering therapy; however, many patien
118 tries where this insecticide class forms the mainstay of malaria control.
119                           Agriculture is the mainstay of Malawi's economy and maize is the most impor
120  if uric acid lowering therapy will become a mainstay of management in diseases other than gout and t
121                                          The mainstay of management includes high-dose corticosteroid
122 eal shockwave lithotripsy (SWL) has been the mainstay of management of urolithiasis; recognized widel
123 SA-AKI by avoiding renal insults remains the mainstay of management.
124 tidiarrheals and biofeedback therapy are the mainstay of management; surgery may be useful in refract
125     Fluoroquinolone-based regimens, once the mainstay of many protocols, are increasingly ineffective
126                       Formalin fixation is a mainstay of modern histopathologic analysis, yet the pra
127 surgery, radiation and chemotherapy) are the mainstay of modern oncologic therapy.
128 ly, nuclear imaging techniques have been the mainstay of molecular imaging in the clinical arena.
129 ases, pathogens and organisms has become the mainstay of molecular science and medicine.
130  (MDA) with preventive chemotherapies is the mainstay of morbidity control for schistosomiasis and so
131                                       EDA is mainstay of multimodal pain management within enhanced r
132                Immunosuppression remains the mainstay of myasthenia gravis treatment.
133         Focussed Ion Beam (FIB) milling is a mainstay of nano-scale machining.
134          While antiresorptive therapy is the mainstay of OI treatment, it has limited efficacy in WNT
135               Somatostatin analogues are the mainstay of oncologic management of bowel NETs; everolim
136 nificantly increasing the effectiveness of a mainstay of oncologic therapy.
137 antagonists, such as warfarin, have been the mainstay of oral anticoagulation for many decades.
138  the mu opioid receptor (muR), have been the mainstay of pain management, but their use is highly lim
139 cement with levodopa (L-DOPA) represents the mainstay of Parkinson's disease (PD) therapy.
140                Dopaminergic drugs remain the mainstay of Parkinson's disease therapy but often fail t
141 oid analgesics are typically embraced as the mainstay of pharmaceutical interventions in this area, t
142                   Afterload reduction is the mainstay of pharmacological treatment of heart failure (
143 eta2-adrenoreceptor agonists (LABA), are the mainstay of pharmacological treatment of stable chronic
144 tural continence mechanism should remain the mainstay of PPI prevention.
145 partum antibiotic prophylaxis is the current mainstay of prevention, reducing early-onset infant dise
146                                 Surgery, the mainstay of primary tumor management, also plays a role
147 ndrogen deprivation therapy (ADTh) remains a mainstay of prostate cancer treatment, but its efficacy
148        Household-based interventions are the mainstay of public health policy against epidemic respir
149 unction and relocation of proteins forms the mainstay of regulatory pathways.
150             Induction immunosuppression is a mainstay of rejection prevention after transplantation.
151 rfusion imaging (MPI), a technique that is a mainstay of risk assessment for ischemic heart disease.
152 errations are known to drive AML and are the mainstay of risk classification.
153 chanisms that cause sudden infant death, the mainstay of risk reduction continues to be a safe sleep
154                    Cisplatin chemotherapy, a mainstay of SCC treatment, promotes dissociation of p63
155                           Opioids remain the mainstay of severe pain management in patients with canc
156       High-throughput screening has become a mainstay of small-molecule probe and early drug discover
157                   Blood transfusions are the mainstay of stroke prevention in pediatric sickle cell a
158 aining for laparoscopic surgery has become a mainstay of surgical training.
159 disease with dopaminergic agents remains the mainstay of symptomatic therapy for this incurable neuro
160                                          The mainstay of syphilis treatment is parenteral penicillin
161 tivity, sputum smear microscopy is still the mainstay of TB diagnosis in resource-limited settings.
162 n-based combination therapies (ACTs) are the mainstay of the current treatment of uncomplicated Plasm
163                                          The mainstay of the diagnosis of vWD is laboratory testing.
164 re workers and other high-risk groups is the mainstay of the public health strategy to combat influen
165 ariants of host-use trade-offs have become a mainstay of theoretical explanations of the prevalence o
166                            Triazoles are the mainstay of therapy against Aspergillus infections for t
167                    Elimination diets are the mainstay of therapy but have been rarely studied.
168            Primary surgical treatment is the mainstay of therapy but the effectiveness and extent of
169 onventional surgical replacement remains the mainstay of therapy for aortic stenosis, transcutaneous
170                      Lithium salts, once the mainstay of therapy for bipolar disorder, have tolerabil
171  Intracranial pressure (ICP) monitoring is a mainstay of therapy for children with traumatic brain in
172    BCR/ABL kinase inhibitors have become the mainstay of therapy for CML, although CML cells can deve
173           Furthermore, acid suppression, the mainstay of therapy for GER, increases the burden of non
174                               Currently, the mainstay of therapy for liposarcoma is surgical excision
175     Although surgical resection has been the mainstay of therapy for localized, primary GIST, postope
176 rosis Factor (anti-TNF) therapy has become a mainstay of therapy for patients with CD who are unrespo
177 and secondary SND, cardiac pacing may be the mainstay of therapy for patients with predominant fibrot
178 oietic stem cell transplantation (HSCT) is a mainstay of therapy for relapsed intermediate-grade B-ce
179 c valve replacement (SAVR) has long been the mainstay of therapy for severe aortic stenosis.
180                                          The mainstay of therapy in DMS patients is medical managemen
181                   Glucocorticoids remain the mainstay of therapy in most cases, though their mechanis
182 lthough administration of epinephrine is the mainstay of therapy of acute anaphylaxis, the interactio
183 , treatment with carbapenem antibiotics is a mainstay of therapy that can lead to the emergence of re
184 re now chemically synthesized and remain the mainstay of therapy to treat malaria.
185          Although corticosteroids remain the mainstay of therapy, many new pharmacological agents hav
186   Although topical steroids continue to be a mainstay of therapy, none are presently Food and Drug Ad
187 ent of bleeding, bypassing agents remain the mainstay of therapy.
188 e cardioverter-defibrillators (ICDs) are the mainstay of therapy.
189                     beta-Betalockers are the mainstay of therapy; when they fail, implantable cardiov
190                                            A mainstay of this narrative is the impact of incidental s
191            Oral anticoagulation (OAC) is the mainstay of thromboembolism prevention, and management o
192     Intracranial pressure (ICP) control is a mainstay of traumatic brain injury (TBI) management.
193                               Radiation is a mainstay of treatment and significantly improves surviva
194                               Surgery is the mainstay of treatment and until recently there have been
195                         Therapies remain the mainstay of treatment and work in this area needs to be
196 ess clear and radical cystectomy remains the mainstay of treatment at this time.
197  HCC, transarterial chemoembolization is the mainstay of treatment but is only possible in a minority
198                     Immunosuppression is the mainstay of treatment but many patients do not tolerate
199                                          The mainstay of treatment for adult MCD, oral glucocorticoid
200    Inhaled corticosteroid (ICS) therapy is a mainstay of treatment for asthma, but the clinical respo
201        Antibiotic-based therapies remain the mainstay of treatment for CDI, but new therapies have be
202                       Artesunate remains the mainstay of treatment for cerebral malaria, but it is le
203    Glucocorticoid replacement therapy is the mainstay of treatment for congenital adrenal hyperplasia
204 , oral valganciclovir are now considered the mainstay of treatment for cytomegalovirus (CMV) infectio
205                 Anticoagulant agents are the mainstay of treatment for deep vein thrombosis and pulmo
206              Cisplatin-based chemotherapy, a mainstay of treatment for disseminated germ cell tumors
207                   Intravenous rituximab is a mainstay of treatment for follicular lymphoma.
208                                          The mainstay of treatment for Gaucher's disease type 1 is al
209  drug that inhibits topoisomerase II, is the mainstay of treatment for HLH, although its therapeutic
210         While radical cystectomy remains the mainstay of treatment for muscle-invasive disease, there
211                                          The mainstay of treatment for NAFLD remains lifestyle modifi
212 only called dual antiplatelet therapy, are a mainstay of treatment for patients with acute coronary s
213 y medical or surgical castration remains the mainstay of treatment for patients with advanced prostat
214               Radiotherapy has long been the mainstay of treatment for patients with head and neck ca
215                            Vancomycin is the mainstay of treatment for patients with Staphylococcus a
216  (PPIs) to endoscopic therapy has become the mainstay of treatment for peptic ulcer bleeding, with cu
217        Antithrombotic therapy represents the mainstay of treatment for prevention of recurrent ischem
218 al studies indicate that antipsychotics, the mainstay of treatment for schizophrenia patients, may al
219                           Opioids remain the mainstay of treatment for severe pain, but the associate
220 l excision with predetermined margins is the mainstay of treatment for squamous-cell carcinoma and fo
221 aded full-thickness blepharotomy remains the mainstay of treatment for the condition.
222                                    While the mainstay of treatment for this devastating condition rem
223       Indefinite anticoagulation remains the mainstay of treatment for thrombotic APS.
224                     Although surgery was the mainstay of treatment for valvular heart disease, transc
225   Inhaled glucocorticosteroids (ICS) are the mainstay of treatment in asthma.
226                  Although azacitidine is the mainstay of treatment in MDS, only half of all patients
227 propriate intravenous antibiotics remain the mainstay of treatment in most cases, novel technologies,
228 ecrosis factor alpha (anti-TNF) therapy is a mainstay of treatment in rheumatoid arthritis (RA).
229                                          The mainstay of treatment is amplification.
230  For non-muscle-invasive bladder cancer, the mainstay of treatment is complete resection of the tumou
231                                   Although a mainstay of treatment is orthopedic repair, a multidisci
232 factor VIII concentrates represents the safe mainstay of treatment of all patients, particularly thos
233 o the agent that is currently considered the mainstay of treatment of CRS, specifically glucocorticoi
234               Steroid therapy is the current mainstay of treatment of idiopathic SSNHL in the United
235 n the use of LMWHs such as enoxaparin as the mainstay of treatment of pediatric provoked VTE; identif
236 -dose methotrexate-based chemotherapy is the mainstay of treatment of primary central nervous system
237             Chemotherapy continues to be the mainstay of treatment of these lesions, but the effects
238 ng a golden period where mAbs are becoming a mainstay of treatment regimes for diseases ranging from
239                                          The mainstay of treatment remains corticosteroids; other med
240 ce and resource burden of bronchiolitis, the mainstay of treatment remains supportive care, which fre
241                      Antibiotic therapy is a mainstay of treatment, although antimicrobial resistance
242  HCC, transarterial chemoembolization is the mainstay of treatment, although there is increasing evid
243 emonstrates that surgery continues to be the mainstay of treatment, and that there is a need to defin
244                          Surgery remains the mainstay of treatment, and the role of adjuvant chemothe
245             Immunosuppressive agents are the mainstay of treatment, but long-term remissions are rare
246                      Although surgery is the mainstay of treatment, radioactive iodine (RAI) is routi
247                        Surgery, which is the mainstay of treatment, should be complemented with antib
248 cal excision with margin control remains the mainstay of treatment, whereas the use of radiotherapy i
249 ral decades, supportive therapies remain the mainstay of treatment.
250 ion of emergency medication is currently the mainstay of treatment.
251 screening of novel therapeutics becoming the mainstay of treatment.
252 tivating agent hydroxyurea are currently the mainstay of treatment.
253               Medical therapy has formed the mainstay of treatment.
254 antipsychotic medications continue to be the mainstay of treatment.
255  patients, where proteasome inhibitors are a mainstay of treatment.
256            Systemic chemotherapy remains the mainstay of treatment; however, the development of multi
257 bined with antibiotic therapy is the current mainstay of treatment; however, the reported duration of
258 ass oral azithromycin distributions remain a mainstay of treatment; studies have assessed the appropr
259                                          The mainstay of tuberculosis care is early detection of acti
260        Incretin mimetics are set to become a mainstay of type 2 diabetes treatment.
261                                          The mainstay of VTE treatment is anticoagulation, while inte
262                   Radiotherapy is one of the mainstays of anticancer treatment, but the relationship
263     Although inhaled glucocorticoids are the mainstays of asthma treatment, they are poorly effective
264 produced by environmental bacteria have been mainstays of both chemical and biological research for d
265              As glass is becoming one of the mainstays of building construction materials, and conduc
266 g, ion pairing, and pi stacking, have become mainstays of catalyst design, the cation-pi interaction
267 puted tomography (CT) and spirometry are the mainstays of clinical pulmonary assessment.
268     Balloon angioplasty and stenting are the mainstays of endovascular therapy.
269 increased physical activity, are the current mainstays of NASH treatment.
270              Diet and exercise represent the mainstays of obesity treatment.
271        Mu-opioid receptor agonists represent mainstays of pain management.
272 both imaging and radioligand therapy are the mainstays of the current success.
273 drenocorticotrophic hormones are the current mainstays of therapy for the treatment of acute optic ne
274 brillator for prevention of sudden death are mainstays of therapy when deemed necessary and appropria
275 cell (RBC) and platelet transfusions are the mainstays of therapy, but data to guide neonatal transfu
276 cal decompression or observation remains the mainstays of therapy.
277 fficacy, half-life, and bioavailability, the mainstays of traditional pharmaceutical screening.
278                                          The mainstays of treatment are immunomodulators and biologic
279 nd prevention of sudden death continue to be mainstays of treatment.
280       Although PET and SPECT remain clinical mainstays, optical readouts of ionizing radiation offer
281 ceptor blockade with tocilizumab remains the mainstay pharmacologic therapy for CRS, though indicatio
282                               Lithium is the mainstay prophylactic treatment for bipolar disorder (BD
283 PCa) after androgen deprivation therapy, the mainstay systemic treatment for PCa.
284 reverse transcriptase inhibitors (NRTIs) are mainstay therapeutics for HIV that block retrovirus repl
285 r necrosis factor-alpha (TNF) antibodies are mainstay therapies for IBD.
286 eart failure (HF) and inhibition of RAS is a mainstay therapy for HF.
287                Glucocorticoids represent the mainstay therapy for many lung diseases, providing outst
288  are the primary target of corticosteroid, a mainstay therapy for problematic IH.
289 hich beta-adrenergic receptor blockers are a mainstay therapy.
290 f AKI, and a preventive strategy remains the mainstay to attenuate its impact.
291 athology; however computed tomography is the mainstay to delineate and characterize lesions in this l
292 d triamcinolone acetonide are pharmaceutical mainstays to treat chronic inflammatory diseases.
293         Intravenous thrombolysis remains the mainstay treatment for acute ischemic stroke.
294    Androgen deprivation therapy (ADT) is the mainstay treatment for advanced prostate cancer.
295                           L-dopa remains the mainstay treatment for Parkinson's disease (PD), althoug
296                              Antibiotics are mainstay treatment for patients with severe COPD with an
297 al resection with mesorectal excision is the mainstay treatment for rectal cancer.
298                   Corticosteroids remain the mainstay treatment in alcoholic hepatitis pending the re
299 an estrogen receptor (ER) antagonist, is the mainstay treatment of breast cancer and the development
300      Glucocorticoids (GCS) remain one of the mainstay treatments in the management of ulcerative coli

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