ライフサイエンスコーパス: major factor

1 mistry, dominated by oxidizing agents, was a major factor.

2 erences in the host response implicated as a major factor.

3 olic insults, of which oxidative stress is a major factor.

4 and T bases, is increasingly recognized as a major factor.

5 hereas genetic factors do not appear to be a major factor.

6 suggest that direct viral cytopathicity is a major factor.

7 determine whether the increase in DCD was a major factor.

8 es and body weight, with nutrition being the major factor.

9 f this hybrid material are attributed to two major factors: 1) the 0D structure allowing the bulk cry

10 cted by inherent or induced resistance, is a major factor affecting epidemic development, supporting

11 The major factor affecting morbidity and mortality after lun

12 The major factor affecting performance of alignment-free rea

13 Insect herbivores are hypothesized to be major factors affecting the ecology and evolution of pla

14 serum hepatitis B virus (HBV) DNA levels are major factors affecting the prognosis of adult HBV carri

15 d host protein shutoff is considered to be a major factor allowing viruses to evade innate and acquir

16 owever, being a young or a male student were major factors, along with being exposed to unpleasant pl

17 Oxygen availability is a major factor and evolutionary force determining the meta

18 h platelet glycoproteins and integrins, is a major factor and represents a therapeutic target in earl

19 An investigation of some of the major factors and their geneses at play in explaining th

20 Other major factors are concomitant renal disease, or use of t

21 rvation-induced dormancy and that HPF is the major factor associated with P. aeruginosa ribosome pres

22 Major factors associated with 25(OH)D level were similar

23 Spontaneous preterm birth (SPTB) is a major factor associating with deaths and with lowered qu

24 ry (rRST) of personality with respect to two major factors: behavioral inhibition system (BIS), fight

25 n selection and a massive cytokine storm are major factors behind increased pathogenicity of SIV upon

26 s above lead to the simple prediction that a major factor causing heterogeneity in Bacillus spore ger

27 d as 'Regulatory Communities.' We reveal two major factors, centromere clustering and transcription f

28 With the three major factors considered, the change in carbon stocks is

29 Gene body methylation (gbM) was a major factor constraining cis-regulatory variation, wher

30 at the outflow vein of hemodialysis AVF is a major factor contributing to failure.

31 lk encounters with lymphatic sinuses are the major factor contributing to LN transit times.

32 entially life threatening; this makes them a major factor contributing to the cost and uncertainty of

33 der and that such CNS immune senescence is a major factor contributing to the development of aging-re

34 There does not appear to be any single major factor contributing to the high levels of placebo

35 s simulated by batch experiments, could be a major factor contributing to the high Pb mobility in the

36 inal neurons is increasingly recognized as a major factor contributing to the pathogenesis of vascula

37 A major factor contributing to the persistence of intoxica

38 cleavage of N-glycosidic bond constitutes a major factor contributing to the selectivity of hTDG tow

39 that organization of the template DNA is the major factor contributing to the stimulation of Pol gamm

40 selection against deleterious mutations is a major factor contributing to these patterns in genome re

41 Variability in FKBP5 expression level is a major factor contributing to variation in response to ch

42 ene polymorphisms, rather than race, are the major factors contributing to apparent differences in th

43 cessing to siRNAs in the cells are among the major factors contributing to differential RNAi efficien

44 that coastal nutrient loading is one of the major factors contributing to the increasing levels of b

45 r, and distribution have been considered the major factors contributing to this biological activity o

46 Major factors contributing to this poor K(+) retention a

47 tumor-associated macrophages (TAMs) are the major factors contributing to tumor progression and meta

48 posed of the proteins PB1, PB2, and PA, is a major factor controlling host adaptation, and reassortme

49 n oxidation, we conclude that urate is not a major factor controlling oxidative stress in vivo.

50 Inorganic phosphate (Pi) availability is a major factor determining growth and consequently the pro

51 by drivers of environmental change may be a major factor determining how global environmental change

52 Lignin is a major factor determining saccharification efficiency and

53 nd its specific large dsDNA virus (EhV) is a major factor determining the fate of carbon in the ocean

54 minated layer (LL), which is thought to be a major factor determining the host response to the infect

55 ak, suggesting that prey abundance was not a major factor determining the location of diving behaviou

56 e acquisition of new parasite clones was the major factor determining the risk of clinical illness (i

57 ng sounds show that covert reactivation is a major factor determining the selectivity of memory conso

58 at an attractive electronic interaction is a major factor determining the stability of the complex be

59 (Z) and size (molecular mass, M) are the two major factors determining electrophoretic mobility, in c

60 veness and TGF-beta-mediated suppression are major factors determining human fetal NK cell hyporespon

61 the N-glycan processing branch point and are major factors determining the net outcome of the insect

62 The three major factors determining the tension distribution are t

63 thermodynamic parameters, evidence that the major factor dictating selectivity in the trapping proce

64 Behavior is expected to be a major factor driving animals' responses to global change

65 stant viridans group streptococci (VGS) is a major factor driving empiric use of an anti-gram-positiv

66 Oxygenation has widely been viewed as a major factor driving the emergence and diversification o

67 favoured explanation and is undoubtedly the major factor driving the frequency change.

68 se results suggest that redox imbalance is a major factor driving the morphogenesis of P. aeruginosa

69 rokaryotes indicate that shared habitat is a major factor driving transfers.

70 This study reveals age and seasonality as major factors driving the composition of the nasal micro

71 No consensus has yet been reached on the major factors driving the observed increase in the seaso

72 It is important to identify major factors driving the successful establishment of th

73 Here we review the major factors due for consideration in both eyelid and r

74 We identify mDia1 and Fmnl3 as major factors enhancing actin polymerization and stabili

75 ic relatedness and geographical proximity as major factors facilitating HTT in insects.

76 ites (RBS) and transcriptional activity were major factors favoring integration.

77 Age has long been used as a major factor for assessing suitability for allogeneic he

78 smission and conduction, is believed to be a major factor for brain's high oxidative demand.

79 ivo, addressing PKD isoform specificity as a major factor for future therapeutic strategies.

80 oding risk variants on gene expression are a major factor for phenotypic variation of complex traits

81 ity of input antigens, and valency was not a major factor for potency or breadth of the response.

82 e analysis identified cone eccentricity as a major factor for predicting K(max) outcome (ss coefficie

83 evels in the prostate are postulated to be a major factor for prostate carcinogenesis and prostate ca

84 ocus Sen1/RSe-XIa on potato chromosome XI as major factor for resistance to all four S. endobioticum

85 tension has been recognized for decades as a major factor for stroke, with observational epidemiologi

86 pped-flow fluorometry implicates k(off) as a major factor for the affinity change at alkaline pH and

87 NF-kappaB constitutive activation is a major factor for the apoptosis resistance of melanoma.

88 autoantibody production by B cells may be a major factor for the autoimmune pathology in mice defici

89 Cigarette smoking is a major factor for the development of pulmonary emphysema

90 Although GLP-1 has been suggested as a major factor for the marked improvement of glucose toler

91 Metabolic syndrome (MetS) is a major factor for the occurrence of cardiovascular events

92 A major factor for the population decline of Native Americ

93 poly(A)-specific exoribonuclease PDE12 as a major factor for the quality control of mitochondrial no

94 trate that sympatric occurrence of bats is a major factor for virus transmission.

95 Major factors for viral entry into epithelial cells are

96 The major factor found to impede current efforts to prevent

97 Clonal growth is a major factor governing maximum lifespan.

98 Temperature is a major factor governing the distribution and seasonal beh

99 f research on APN effectiveness to date, two major factors have emerged in developing future studies,

100 We show that glycosylation is a major factor impacting DPP4 receptor function.

101 Acute rejection is a major factor impacting survival in the first 12 months a

102 of conditional, alternative strategies is a major factor in adaptation.

103 ges in a single mutational step and may be a major factor in adaptive evolution.

104 ability that increasingly is recognized as a major factor in ALD.

105 ic neuron at the neuromuscular junction is a major factor in AMAN.

106 Recognition of DNA might be a major factor in antimicrobial immune responses against c

107 study implicated ultraviolet radiation as a major factor in both the initiation and progression of m

108 dings demonstrate that IDH2 activities are a major factor in cancer, and as such, these results impli

109 udies demonstrated that the S17 insert was a major factor in cell culture adaptation.

110 ions from airway mucous glands that may be a major factor in CF pathology.

111 Pol II dissociation after transcription is a major factor in chromatin disruption and that it may be

112 organizing system (MICOS) was found to be a major factor in CJ formation.

113 Pase (V-ATPase) activity of tumor cells is a major factor in control of cytoplasmic and extracellular

114 CALM is thus a major factor in controlling CCV size and maturation and

115 ted that the Mdm2 ubiquitin ligase acts as a major factor in controlling p53 stability and activity i

116 m the long-range action of tropomyosin are a major factor in cooperative activation, with each additi

117 icating the role of female sex hormones as a major factor in determining migraine risk and characteri

118 A major factor in determining steady state proved to be th

119 nd turn formation in the unfolded state is a major factor in determining the folding dynamics.

120 ability of a mutant RT in virions could be a major factor in determining the virus titer and, by exte

121 Behavioral persistence is a major factor in determining when and under which circums

122 ence that self-reactive CD8(+) T cells are a major factor in development and progression of type 1 di

123 omerular epithelial cell, the podocyte, as a major factor in disease pathogenesis.

124 linator-mediated reproductive isolation is a major factor in driving the diversification of flowering

125 m vulnerability to embolism is emerging as a major factor in drought-induced tree mortality events ac

126 ising from KCNE2-dependent achlorhydria is a major factor in early-onset NAFLD in Kcne2( horizontal l

127 Biological activity is a major factor in Earth's chemical cycles, including facil

128 alled bioluminescence, is considered to be a major factor in ecological interactions.

129 ion of these domains does not appear to be a major factor in evolution of these orthologous families.

130 ctus, leading to speculation that this was a major factor in expansion.

131 Inflammation is a major factor in heart disease.

132 ronic hepatitis B virus (HBV) infection is a major factor in hepatocellular carcinoma (HCC) pathogene

133 s underlying context-induced drug relapse, a major factor in human drug addiction.

134 lin resistance during weight gain could be a major factor in increasing the cardiometabolic risk of A

135 Because the microbiome is a major factor in mammalian physiology, we aimed to identi

136 Aging is a major factor in many cardiovascular diseases.

137 ted Tau with 14-3-3zeta are supposed to be a major factor in microtubule destabilization, the binding

138 Overexpression of RND-type efflux pumps is a major factor in multidrug resistance (MDR), which makes

139 on, it is not clear if drug formulation is a major factor in optimizing pharmacodynamics using this t

140 D), where transcriptional dysregulation is a major factor in pathogenesis.

141 ochondrial oxidant stress is widely viewed a major factor in PD pathogenesis.

142 Growth is a major factor in plant organ morphogenesis and is influen

143 s show how age-targeted predation could be a major factor in population decline of K-selected colonia

144 that the composition of the microbiota is a major factor in pre-determining the type and robustness

145 The degree of tumor removal at surgery is a major factor in predicting outcome for ovarian cancer.

146 esses macrophage-mediated inflammation, is a major factor in promoting clinical disease in muscle.

147 that proximity in the primary structure is a major factor in promoting helix formation and associatio

148 f K(+) ions from the selectivity filter is a major factor in promoting inactivation, which defeats tr

149 ort RA to Cyp26 enzymes for degradation is a major factor in promoting robustness.

150 issue contact force (CF) is believed to be a major factor in radiofrequency lesion size.

151 If reduced drug uptake is a major factor in resistance, hCTR1 is unlikely to be a pr

152 ABT-263 or ABT-737 and is considered to be a major factor in resistance.

153 tnerships--the analog of life partners--as a major factor in science career development.

154 e albedo contrast between water and ice is a major factor in seasonal sea ice retreat, and has receiv

155 functions, developmental plasticity can be a major factor in shaping the overall phenotypes of geneti

156 rimary determinant of local recurrence and a major factor in survival in rectal cancer.

157 st that recognition of such neoantigens is a major factor in the activity of clinical immunotherapies

158 thmic cortical feedback to the thalamus is a major factor in the amplification of thalamocortical osc

159 thmic cortical feedback to the thalamus is a major factor in the amplification of thalamocortical osc

160 traviolet or ionizing gamma rays, and is the major factor in the conditioned medium that leads to the

161 Cytotoxic T lymphocytes (CTL) are a major factor in the control of HIV replication.

162 ther, these findings identify gigaxonin as a major factor in the degradation of cytoskeletal IFs and

163 s in the cytoplasm of motor neurons may be a major factor in the development of ALS.

164 without viral protein expression would be a major factor in the development of cancer in individuals

165 the hypothesis that NAA accumulation is the major factor in the development of CD.

166 ms suggest that dietary diversification is a major factor in the earliest mammaliaform evolution.

167 Age-related diastolic dysfunction is a major factor in the epidemic of heart failure.

168 Whole genome duplication (WGD) is a major factor in the evolution of multicellular eukaryote

169 regulator of cartilage differentiation was a major factor in the evolution of the vertebrate head ske

170 ersification of paired appendages has been a major factor in the evolutionary radiation of vertebrate

171 ost frequent cause for the common cold and a major factor in the exacerbation of chronic pulmonary di

172 ave stayed behind, and with no health care a major factor in the flight of refugees, the effect exten

173 (iii) The major factor in the heterogeneity in germination of indi

174 decreased grazing pressure is likely to be a major factor in the increased abundance of both diatoms

175 x changes in titin occur that combined are a major factor in the increased passive myocardial stiffne

176 Colonization density was found to be a major factor in the level of pneumococcal shedding and r

177 hat full-length Ikaros (IK-1) functions as a major factor in the maintenance of viral latency in Epst

178 croenvironment, such as myeloid cells, are a major factor in the overall prognosis of malignant disea

179 ar activities lead to genomic instability, a major factor in the pathogenesis of cancer and other dis

180 level resistance to antimicrobial drugs is a major factor in the pathogenesis of chronic Staphylococc

181 phylococcus aureus (MRSA) strain USA300 is a major factor in the pathogenesis of severe pneumonia and

182 onalcoholic fatty liver disease (NAFLD) is a major factor in the pathogenesis of type 2 diabetes (T2D

183 coholic fatty liver disease (NAFLD) and is a major factor in the pathogenesis of type 2 diabetes.

184 ellular spreading of protein assemblies is a major factor in the progression of neurodegenerative dis

185 immunodeficiency virus coinfection is not a major factor in the United States, since only approximat

186 A major factor in the variation of SUMO-target function is

187 nating the bacterial cloning step has been a major factor in the vastly improved efficiency of massiv

188 s, suggesting that recent gene flow is not a major factor in their formation.

189 Here, we demonstrate that a major factor in this process involves epigenetic changes

190 arrhythmias, and sympathetic discharge is a major factor in triggering TdP in female long-QT syndrom

191 CONSTITUTIVELY PHOTOMORPHOGENIC 1 (COP1), a major factor in UV-B signaling.

192 y loss, so this property is unlikely to be a major factor in vivo.

193 m plants to neighbouring plants, can both be major factors in determining non-random herbivore distri

194 dence that gender, age and disease class are major factors in determining the structure of the diseas

195 in corresponding areas, suggesting these as major factors in psychopathology.

196 These events are major factors in regulation of zinc homeostasis.

197 not HIR) and liver triglyceride content are major factors in the elevation of plasma aminotransferas

198 otein misfolding and aggregation are seen as major factors in the pathogenesis of Parkinson's disease

199 ophagy is reportedly either irrelevant, or a major factor, in the lethal cardiomyopathy evoked by car

200 sults suggest that body size should not be a major factor influencing dose reduction decisions in wom

201 of words they know when they enter school, a major factor influencing subsequent school and workplace

202 The major factor influencing the reaction rate constants of

203 Here we present evidence that RecG is a major factor influencing these processes in bacteria.

204 Major factors influencing adherence were: non-disclosure

205 Bacteria are not considered among the major factors influencing coccolithophore physiology.

206 The major factors influencing the structural arrangement and

207 Although ubiquitination has emerged as a major factor involved in RIG-I activation, the potential

208 h factor (VEGF) is generally accepted as the major factor involved in the process of angiogenesis.

209 A major factor involved in this effect is consumption of u

210 Weight loss improves the major factors involved in the pathogenesis of T2DM, name

211 utant, revealing that both PHR1 and PHL1 are major factors involved in the regulation of iron homeost

212 An additional major factor is the ion shape: Fully convex ions driftin

213 A major factor is the presence in the protein of a segment

214 One of the major factors is phase transformation, with change to mo

215 Ischemia-reperfusion (I/R) injury is a major factor leading to intestinal dysfunction or graft

216 tension in the carotenoid structure were the major factors leading to the increase of ROO() scavengin

217 Correspondence noise is a major factor limiting direction discrimination performan

218 nic lung allograft dysfunction (CLAD) is the major factor limiting long-term success of lung transpla

219 epitope by quaternary constraints was not a major factor limiting neutralization.

220 Chilling stress is a major factor limiting plant development and crop product

221 Development of drug resistance is a major factor limiting the continued success of cancer ch

222 to the extravascular tumor tissue is often a major factor limiting the efficacy of cancer treatments.

223 genic plants has long been hypothesized as a major factor limiting the production of industrially use

224 Disease relapse remains a major factor limiting the survival of cancer patients.

225 The major factor limiting the use of VE analogues is their l

226 However, viral disease is still a major factor limiting tomato production.

227 traits and their thermal dependence are two major factors limiting the CO2 assimilation potential of

228 rived suppressor cells (MDSC) are one of the major factors limiting the immune response in cancer.

229 , we demonstrated that HNRNPU functions as a major factor maintaining 3D chromatin architecture, sugg

230 Toxoplasma ROP18 Ser/Thr protein kinase as a major factor mediating acute virulence in mice.

231 pores by reactive oxygen species (ROS) is a major factor mediating intermitochondrial coupling, and

232 Agrin is the major factor mediating the neuronal regulation of postsy

233 of the HLA-viral peptide interaction as the major factor modulating durable control of HIV infection

234 Epistaxis is a major factor negatively affecting quality of life in pat

235 c analyses unveil the AICAR/NTP balance as a major factor of AICAR antiproliferative effects.

236 For these elements mining is the major factor of anthropogenic influence, whereas petrole

237 ol crystals (ChCs) have been identified as a major factor of plaque vulnerability and as a potential

238 and number of maskers used were found to be major factors on the value of the slope of the psychomet

239 ngoing central nervous system infection is a major factor perpetuating the debate.

240 Three major factors predicting the utilization of dental servi

241 ological habitat connectivity by dams is the major factor reducing climate change resilience.

242 resynaptic sensor-membrane interactions as a major factor regulating the speed of the release machine

243 e, we summarize current understanding of the major factors regulating protein expression.

244 s and the high expression of miR-21 were the major factors related to the poor prognosis of patients.

245 ctor under hypoxia (RafH) and that it is the major factor responsible for DosR-mediated hypoxic survi

246 IFN-gamma was identified as the major factor responsible for Th-1-induced DC tumoricidal

247 These observations indicate that the major factor responsible for the cognitive impairment in

248 ate that these molecules do not comprise the major factors responsible for stimulating TLR2 by whole

249 ion on variability at linked sites, may be a major factor shaping genome-wide patterns of genetic div

250 Inflammation is a major factor shaping outcome during the early, acute pha

251 suggest that the transmission mechanism is a major factor shaping pathogen-induced changes in host-pl

252 ontane systems has long been recognized as a major factor shaping plant community biodiversity, metab

253 of predation or interference competition are major factors shaping the distribution of species.

254 ndicating that the hydrophobic effect is the major factor stabilizing the dimer, and suggesting that,

255 mmatory response (IBMIR) has been shown as a major factor that causes damage to transplanted islets.

256 This identifies ATM as a major factor that controls germination in aged seeds, in

257 ranes is cooperative and identifies SPA as a major factor that controls this cooperativity.

258 A major factor that determines influenza A virus fitness a

259 A major factor that directs Hsp70 signaling activity appea

260 sed body weight after smoking cessation as a major factor that interferes with their attempts to quit

261 ess associated with drought or salinity is a major factor that limits plant productivity.

262 Thus, although thymic tolerance is not a major factor that limits protective T cell responses, th

263 posure; hence, specimen movement is a second major factor that limits resolution.

264 rved Ctf19/CCAN kinetochore sub-complex as a major factor that minimizes potentially deleterious cent

265 Premature rupture of membranes (PROM) is a major factor that predisposes women to preterm delivery.

266 therefore, the heading bias constitutes the major factor that produces the chemotactic drift.

267 The background signal is a major factor that restricts the limit of detection of bi

268 cies from the photocatalytic coatings is the major factor that significantly reduces the bacterial gr

269 One major factor that stabilizes miRNAs and siRNAs in plants

270 imuli, vision science has identified several major factors that affect detection thresholds, includin

271 particularly in right lobe liver grafts, are major factors that contribute to biliary complications i

272 swimming direction and speed biases are two major factors that contribute to their tactic drift moti

273 the tri-dimensional shape of the PS are the major factors that determine cellular uptake, subcellula

274 The two major factors that drove the nature of connectivity abno

275 In this review, we focus on three major factors that ensure optimal brain perfusion and fu

276 nhouse Gases (GHG) and Land Use (LU) are the major factors that gave rise to warming during the 20(th

277 One of the major factors that have impeded rapid progress in these

278 lular pH (pHe) of living cells is one of the major factors that influence cell behaviors including cy

279 Astrocyte cellular edema is one of the major factors that leads to high morbidity post-mTBI.

280 Major factors that promote TBMM acceptability include th

281 Salinization is one of the major factors that threaten the existence of plants worl

282 recognition and TF activation involves three major factors: the cellular network, protein and DNA as

283 Although being a major factor to influence the thermo-tolerance of bacter

284 etic proteins in the reactive astrocytes are major factors to inhibit OL differentiation of OPCs and

285 tumor necrosis factor alpha (TNF-alpha) as a major factor triggering cancer cell immunosuppression ag

286 ound-dependent variation in collaterals is a major factor underlying differences in ischemic tissue i

287 stress-induced cardiac myocyte growth) is a major factor underlying heart failure.

288 stress-induced cardiac myocyte growth) is a major factor underlying heart failure.

289 cating that deficits in WM development are a major factor underlying impaired brain growth and microc

290 ed decline in Sirt3 protective function is a major factor underlying increasing mitochondrial oxidati

291 l oxidative stress is widely posited to be a major factor underlying the loss of substantia nigra par

292 the notion that altered RNA metabolism is a major factor underlying the pathogenesis of ALS.

293 paired protein glycosylation seems to be the major factor underlying these defects although disturban

294 A major factor underlying this is reduced neovascularizati

295 We characterized 3 major factors underlying this effect.

296 Tumour heterogeneity is a major factor undermining the success of therapies target

297 These data implicate FGF2 as a major factor VAT releases to transform epithelial cells-

298 The liver is a major factor VIII (FVIII) synthesis site, and mesenchyma

299 It is believed that feed composition is a major factor which determines the physicochemical charac

300 ond stabilization of helical structures is a major factor, which determines sequence-dependent behavi