ライフサイエンスコーパス: malate

1 xpress the ME genes and is unable to utilize malate.

2 t, followed by the binding of oxaloacetate/L-malate.

3 building up the ester side chain to sinapoyl malate.

4 th cell-permeable GSH monoethylester but not malate.

5 hat catalyses the hydration of fumarate into malate.

6 yzes the reversible hydration of fumarate to malate.

7 s enhancing nocturnal CO2 fixation to stored malate.

8 ary RCH were treated with systemic sunitinib malate.

9 cretion of organic acids such as citrate and malate.

10 ylated sugar intermediates and of starch and malate.

11 apillary RCH treated with systemic sunitinib malate.

12 rticularly the roles of starch, sucrose, and malate.

13 nce via a novel mechanism involving sinapoyl malate.

14 [1-(13)C]alanine, [1-(13)C]malate, [4-(13)C]malate, [1-(13)C]aspartate, [4-(13)C]aspartate, and [(13

15 [1-(13)C]lactate, [1-(13)C]alanine, [1-(13)C]malate, [4-(13)C]malate, [1-(13)C]aspartate, [4-(13)C]as

16 cbl1 plants exudated less Al-chelating malate, accumulated more Al, and displayed a severe root

17 tense) leaves, phaselic acid (2-O-caffeoyl-L-malate) accumulates to several mmol kg(-1) fresh weight

18 These perturbations paralleled reduced malate accumulation at dawn and decreased nocturnal star

19 optimizing CAM-associated dark CO2 fixation, malate accumulation, CAM productivity, and core circadia

20 The increased longevity provided by malate addition did not occur in fumarase (fum-1), glyox

21 ion of glucose, glycerol 3- and 2-phosphate, malate, alanine, myo-inositol, and linoleic acid.

22 igher levels of oxaloacetate, aspartate, and malate, along with increased (13)C label exchange rates

23 Malate, along with potassium and chloride ions, is an im

24 Malate also increased NADPH, NAD, and the NAD/NADH ratio

25 VHL) disease treated with systemic sunitinib malate, an agent that inhibits both anti-vascular endoth

26 Ultraviolet spectroscopy of sinapoyl malate, an essential UV-B screening agent in plants, was

27 med) are 2.73 for oxidation of pyruvate plus malate and 1.64 for oxidation of succinate.

28 ate and its downstream metabolites, [1-(13)C]malate and [1-(13)C]aspartate.

29 In addition, signal from [4-(13)C]malate and [4-(13)C]aspartate was markedly blunted and s

30 reduced Km [PEP] coupled with elevated I50 [malate and Asp] values) via in vivo deubiquitination of

31 The appearance of asymmetrically enriched malate and aspartate indicated high rates of anaplerotic

32 ppc2 mutant greatly reduced the synthesis of malate and citrate and severely suppressed ammonium assi

33 20 d of development to correlate changes in malate and citrate exudation with PEPC activity, posttra

34 tion of the Al(3+) -chelating organic acids, malate and citrate.

35 thioesterase that hydrolyzes malyl-CoA into malate and CoA.

36 h the PEP carboxylase competitive inhibitors malate and diethyl oxalacetate (DOA) in the strong isopr

37 Both malate and DOA did not alter the sensitivity of isoprene

38 Malate and fumarate addition increased oxygen consumptio

39 ation to the cell wall and the organic acids malate and fumarate and decreased allocation to starch a

40 tribute to the lifespan extension induced by malate and fumarate by increasing the amount of oxidized

41 previously with an impaired accumulation of malate and fumarate in leaves.

42 lacking AtQUAC1 accumulated higher levels of malate and fumarate.

43 upplying the ppc1/ppc2 mutant with exogenous malate and glutamate, suggesting that low nitrogen statu

44 Malate and lactate dehydrogenases (MDH and LDH) are homo

45 Lactate levels, lactate/malate and lactate/pyruvate ratios were elevated in HKCs

46 pression of maeP and maeE is induced by both malate and low pH, and induction in response to both cue

47 Some metabolites, such as malate and Man, appeared in the models for both conducta

48 Additional structures of the complex with malate and of the apo form of GlcB supported that hypoth

49 ially NADPH-producing pathways involving (S)-malate and ornithine, quorum sensing, sporulation, and c

50 d is its catalysis of the interconversion of malate and oxaloacetate in the tricarboxylic acid cycle.

51 ine, aspartate, cysteine, glutamine, lysine, malate and pyroglutamate.

52 sensitivity to the preferred carbon sources malate and succinate and, at the same time, mediate lowe

53 Malate and succinate were found to bind to the membrane-

54 LND inhibits the formation of fumarate and malate and suppresses succinate-induced respiration of i

55 quently, this oxaloacetate is converted into malate and then pyruvate, ostensibly increasing the NADP

56 ng its sensitivity to feedback inhibition by malate and thus enhancing nocturnal CO2 fixation to stor

57 es fumarate hydratase to convert fumarate to malate and uses oxaloacetate decarboxylating malic dehyd

58 three different substrates (L(+)-tartrate, D-malate, and 3-isopropylmalate).

59 of 19 traits, including sucrose, ascorbate, malate, and citrate levels.

60 tes including alpha-KG, succinate, fumarate, malate, and citrate were observed in TGF-beta1-different

61 erts isocitrate and acetyl-CoA to succinate, malate, and CoA.

62 L-Arginine, L-glutamine, DL-histidine, malate, and DL-ornithine promoted swarming on several ty

63 ally relevant concentrations of pyruvate and malate, and flux of respiration, NAD(P)H fluorescence, a

64 ncomitant accumulation of the MDH substrate, malate, and fumarate, its immediate precursor in the Kre

65 lular levels of lactate, succinate, alanine, malate, and fumarate.

66 lite analysis indicated increased succinate, malate, and Glc-6-P and decreased Fru-1,6-bisphosphate,

67 abolic signatures such as high raffinose and malate, and low fumarate contents that could reflect cor

68 itrate, 2-oxoglutarate, succinate, fumarate, malate, and oxaloacetate) were tested for their influenc

69 riptan, eletriptan hydrobromide, almotriptan malate, and rizatriptan benzoate tablets.

70 ull assimilatory flux to produce glyoxylate, malate, and succinate.

71 ral function affording bacterial growth on D-malate as a carbon source, the D-malate dehydrogenase of

72 sIII, and is required for normal growth with malate as a sole carbon source.

73 umarate, so conversion of this metabolite to malate as detected by (13)C-magnetic resonance spectrosc

74 at heart mitochondria utilizing pyruvate and malate as substrates at both subsaturating and saturatin

75 displayed lower production of aspartate and malate, as well as reduced k(pyr->asp) and (13)C-label e

76 eurons on 2.5-5 mm glucose depends on ARALAR-malate aspartate shuttle (MAS), with a 46% drop in arala

77 revealed that retinas use activities of the malate aspartate shuttle to protect >98% of their glutam

78 ism by which GOT2 acetylation stimulates the malate-aspartate NADH shuttle activity and oxidative pro

79 ere we find that the absence of a functional malate-aspartate NADH shuttle caused by aralar/AGC1 disr

80 mitochondria, is the regulatory step in the malate-aspartate NADH shuttle, MAS.

81 r Aralar/AGC1 (Slc25a12), a component of the malate-aspartate shuttle (MAS), is stimulated by modest

82 relies on shuttle mechanisms, including the malate-aspartate shuttle and the glycerol-3-phosphate sh

83 t a profound reliance on glucose metabolism, malate-aspartate shuttle deregulation leads to a specifi

84 The malate-aspartate shuttle is indispensable for the net tr

85 The malate-aspartate shuttle is operated by two pairs of enz

86 Hyperacetylation of mitochondrial malate-aspartate shuttle proteins impaired the transport

87 drogenase (MDH) operate as components of the malate-aspartate shuttle, in which a reducing equivalent

88 partate/glutamate carriers is central to the malate-aspartate shuttle, urea cycle, gluconeogenesis an

89 Reduced levels of aspartate deregulated the malate-aspartate shuttle, which is important for cytopla

90 ate carrier 1 (AGC1), a key component of the malate-aspartate shuttle.

91 eotide breakdown and partial reversal of the malate/aspartate shuttle.

92 d modestly reduced nonfermentative growth on malate at both pH 7.5 and 10.5.

93 e with increased levels of fruit citrate and malate at breaker stage to identify a metabolic engineer

94 derably reduced capacity to grow on limiting malate at high pH.

95 he restoration of respiration with glutamate/malate back to control levels.

96 catalyze the oxidative decarboxylation of D-malate-based substrates with various specificities.

97 The broader role of a malate/beta-methylmalate synthase in human physiology an

98 We report that CLYBL encodes a malate/beta-methylmalate synthase, converting glyoxylate

99 the reverse direction (malate dehydration), malate binds the protonated form of the enzyme, and a pr

100 oascorbic (DHAA) acids and validated in 20mM malate buffer (pH 3.8).

101 o CoA) by HCT2 was observed with p-coumaroyl-malate but not phaselic acid.

102 studied: calcium carbonate, calcium citrate malate, calcium phosphate and calcium bisglycinate.

103 Malate can be synthesized from fumarate by the enzyme fu

104 haliana Our results also show that exogenous malate can rescue the long-root phenotype of lpi5 and lp

105 lling the production of organic acid anions (malate, citrate) that are excreted in copious amounts by

106 accumulation of key organic acids, including malate, citrate, dehydroascorbate, and threonate, in pep

107 hat chemically reduce iron(III) from citrate-malate complexes.

108 e roots constitutively and had 2-fold higher malate concentrations in the xylem sap than nulls, indic

109 3)C-label exchange rate between pyruvate and malate, consistent with down-regulated gluconeogenesis.

110 lar reductions in both fumarase activity and malate content as observed in tomato fruit expressing th

111 Modulation of the malate content of tomato (Solanum lycopersicum) fruit by

112 The alternative malate decarboxylase, NADP-ME, did not appear to compens

113 ) catalyze two key steps during light-period malate decarboxylation that underpin secondary CO(2) fix

114 In the reverse direction (malate dehydration), malate binds the protonated form of

115 The kinetics of malate dehydrogenase (MDH) catalyzed oxidation/reduction

116 Two isoenzymes of malate dehydrogenase (MDH) operate as components of the

117 hosphate, reduced are used by NADP-dependent malate dehydrogenase (MDH) to reduce OAA to malate, thus

118 Malate dehydrogenase (MDH), a key enzyme in the tricarbo

119 MDH2 encodes mitochondrial malate dehydrogenase (MDH), which is essential for the c

120 peroxisomal NADH is reoxidised to NAD(+) by malate dehydrogenase (Mdh3p) and reduction equivalents a

121 Mitochondrial malate dehydrogenase (mMDH; EC 1.1.1.37) has multiple ro

122 as activated primary T cells, that cytosolic malate dehydrogenase 1 (MDH1) is an alternative to LDH a

123 X5 (PEX5C) receptor construct or peroxisomal malate dehydrogenase 1 (pMDH1) cargo protein into sunflo

124 led to increased nitrogen assimilation, NADP-malate dehydrogenase activation, and light vulnerability

125 alate valve capacity, with decreases in NADP-malate dehydrogenase activity (but not protein levels) a

126 ys using liver extract revealed up-regulated malate dehydrogenase activity, but not aspartate transam

127 n into two target proteins (Escherichia coli malate dehydrogenase and human histone H3) caused homoge

128 alanine amino transferase and glutamate and malate dehydrogenase and malate, there are no links betw

129 cytochrome-C) and others (creatine kinase M, malate dehydrogenase cytosolic, fibrinogen and parvalbum

130 HG is generated by lactate dehydrogenase and malate dehydrogenase in response to hypoxia.

131 growth on D-malate as a carbon source, the D-malate dehydrogenase of Escherichia coli (EcDmlA) natura

132 The heat-denatured malate dehydrogenase that did not refold by the assistan

133 trate channeling (e.g., of oxaloacetate from malate dehydrogenase to citrate synthase), and use of al

134 rase and further oxidized to oxaloacetate by malate dehydrogenase with the accompanying reduction of

135 ctor protein (SteA), and a metabolic enzyme (malate dehydrogenase), and demonstrate practical applica

136 ption of few outlier loci (notably mtDNA and malate dehydrogenase), the positions and slopes of Fundu

137 ycle components, including citrate synthase, malate dehydrogenase, and aconitase, resulted in a one-c

138 d interfacial residues between mitochondrial malate dehydrogenase, citrate synthase, and aconitase we

139 uch as fructose-1,6-bisphosphatase (FBPase), malate dehydrogenase, isocitrate lyase, and phosphoenolp

140 es with isolated lactate dehydrogenase-1 and malate dehydrogenase-2 revealed that generation of 2-HG

141 d two key enzymes-glycerol dehydrogenase and malate dehydrogenase-were overexpressed to improve PA ti

142 nzymes with multiple isoforms, aconitase and malate dehydrogenase.

143 hose substrates include the short-lived Mdh2 malate dehydrogenase.

144 tamate oxaloacetate transaminases (GOT), and malate dehydrogenases (MDH).

145 nd MDH2 encoding mitochondrial and cytosolic malate dehydrogenases, respectively; and (iv) GLN1 encod

146 Lifespan extension induced by malate depended upon the longevity regulators DAF-16 and

147 ion during therapy, treatment with sunitinib malate did not improve visual acuity or reduce the size

148 Despite these conditions, sinapoyl malate displays anomalous spectral broadening extending

149 ntext of current models of the importance of malate during tomato fruit ripening.

150 that increasing OsALMT4 expression affected malate efflux and compartmentation within the tissues, w

151 way for the biosynthesis of hydroxycinnamoyl-malate esters in plants.

152 d to form the corresponding hydroxycinnamoyl-malate esters in vitro.

153 cue the long-root phenotype of lpi5 and lpi6 Malate exudation is required for the accumulation of Fe

154 Root malate exudation is the major contributor to Arabidopsis

155 o underlie Arabidopsis Al tolerance via root malate exudation, known as SENSITIVE TO PROTON RHIZOTOXI

156 culates as ferric complexes with citrate and malate (Fe(III)3Cit2Mal2, Fe(III)3Cit3Mal1, Fe(III)Cit2)

157 Malate feeding resulted in the inhibition of net assimil

158 We detected signals from fumarate and malate following intravenous administration of hyperpola

159 EMC pathway product glyoxylate, resulting in malate formation.

160 petitive inhibition, excluding the substrate malate from binding to the active site.

161 anion channel responsible for the release of malate from guard cells, is essential for efficient stom

162 histologically, production of [1,4-(13)C(2)]malate from hyperpolarized [1,4-(13)C(2)]fumarate in the

163 Production of [1,4-(13)C(2)]malate from hyperpolarized [1,4-(13)C(2)]fumarate increa

164 The active endobacterium likely extracted malate from the fungal host as the primary carbon substr

165 e lines overexpressing (OX) OsALMT4 released malate from the roots constitutively and had 2-fold high

166 of various metabolites including sucrose and malate (from several potential sources; including guard

167 schemia, PTP opening may result in succinate/malate-fueled ROS production from complex III due to act

168 ne), tricarboxylic acid cycle intermediates (malate, fumarate), glutamate, fatty acid acylcarnitines,

169 sensitivity, including alpha-ketoglutarate, malate, fumarate, succinate, 2-hydroxyglutarate, citrate

170 ome metabolites, including Glc-6-P, Fru-6-P, malate, fumarate, Xyl, and ribose.

171 rowth yields of B. pseudofirmus OF4 cells on malate further revealed that the c12 mutants have a cons

172 ormances of such LDA model, were found to be malate, glucose, fructose, glutamine and succinate.

173 gen flux after the addition of glutamate and malate (GM), adenosine diphosphate (d), succinate (S) an

174 poIIIJ showing respectively greater roles in malate growth at pH 7.5 and 10.5.

175 trate, isocitrate and the two enantiomers of malate have been studied by (1)H NMR titration experimen

176 irst-line imatinib and second-line sunitinib malate have improved progression-free and OS rates.

177 ntrations of citrate, and to a lesser extent malate, have a major impact on nucleus-encoded transcrip

178 products acetate, propionate, succinate and malate; (ii) the potential use of carbon monoxide as an

179 lts of this study collectively indicate that malate importantly controls the chloroplast reductive st

180 yme (ME), the primary enzyme decarboxylating malate in bundle sheath cells to supply CO(2) to Rubisco

181 nulls, indicating greater concentrations of malate in the apoplast.

182 the reversible oxidative decarboxylation of malate in the presence of NADP.

183 ions in reporter strains grown on glucose or malate, including very weakly transcribed genes under st

184 , KCS combinations of glutamate, citrate and malate increased PFP (from 1.22 to 1.29 mmol peroxides/k

185 ges in isoprene emission rate in control and malate-inhibited leaves were associated with changes in

186 Malate inhibition of isoprene emission was associated wi

187 Malate is a central metabolite involved in a multiplicit

188 Cabozantinib S-malate is a vascular endothelial growth factor receptor

189 closure, there is controversy as to whether malate is also metabolised.

190 sides the active site, where the substrate S-malate is bound bidentate to the unique iron of the [4Fe

191 The role of sinapoyl malate is confirmed through the use of a mutant compromi

192 Although malate is exported from guard cells during stomatal clos

193 Copper-malate is shown to have a 5/6-O-ring structure, and Cu-e

194 Both citrate and malate levels were increased in ripe fruit of the transg

195 lenced plants, phaselic acid and p-coumaroyl-malate levels were reduced to <5% that of wild-type cont

196 h was coordinated predominantly by phosphate/malate ligands.

197 ented changes in primary pump activities and malate (Mal) synthesis imposed over a diurnal cycle.

198 Systemic sunitinib malate may be useful in slowing progression of ocular di

199 in this small series, and systemic sunitinib malate may not be safe for treatment of RCH when used at

200 ains predicted to impact the activity of the malate metabolic pathway.

201 carboxykinase (PEPCK), an enzyme involved in malate metabolism and gluconeogenesis, is necessary for

202 These results show that malate metabolism is important during dark-induced stoma

203 Therefore, to increase lifespan, malate must be first converted to fumarate, then fumarat

204 ose, lactate, alanine, glycerol 3-phosphate, malate, myo-inositol, or stearic acid tissue concentrati

205 l b, fructose, fumarate, glucose, glutamate, malate, nitrate, starch, sucrose, total amino acids, and

206 he dark or in nonphotosynthetic tissues, the malate-OAA shuttle was proposed to be mediated by the co

207 time courses of the hydration of fumarate to malate obtained over a wide range of buffer and substrat

208 oyl-CoA derivatives, HCT2 favors transfer to malate of p-coumaroyl and feruloyl moieties over caffeoy

209 ivery pathways to the bundle sheath (BS; via malate or aspartate), and rates of phosphoglyceric acid

210 the predominance of Mn(II), bound mostly to malate or citrate, in roots and stems of all four specie

211 mulated in vacuoles as either soluble Mn(II) malate or citrate.

212 ochondria (n = 7) for glycolysis (pyruvate + malate)- or FA (palmitoylcarnitine)-derived substrates,

213 bution of isotopes when (13)C-glucose, (13)C-malate, or (13)C-pyruvate was provided as a substrate to

214 ure following incubation with abscisic acid, malate, or citrate.

215 ase, converting glyoxylate and acetyl-CoA to malate, or glyoxylate and propionyl-CoA to beta-methylma

216 in lipid vesicles catalyzed the exchange of malate, oxaloacetate, and aspartate for phosphate plus a

217 graphic analyses with succinate, fumarate, L-malate, oxaloacetate, pyruvate and D- and L-2HG support

218 duction-oxidation (redox) homeostasis is the malate-oxaloacetate (OAA) shuttle.

219 ase (MDH) catalyzed oxidation/reduction of L-malate/oxaloacetate is pH-dependent due to the proton ge

220 found that in glucose grown cells, both the malate/oxaloacetate shuttle and a glycerol-3-phosphate d

221 alents are transferred to the cytosol by the malate/oxaloacetate shuttle.

222 required for expression of genes encoding a malate permease (maeP) and malic enzyme (maeE).

223 A malate-phosphate anti-porter DctA is regulated by RpoN a

224 hydrogen peroxide emission using pyruvate + malate (PM) or succinate + rotenone (SR) as substrates.

225 ing in increased [(13)C]-glucose flux toward malate production, potentially explaining the susceptibi

226 relevant ligands such as EDTA, citrate, and malate provided a bridge between spectroscopic studies a

227 ing to cytosolic glucose carbon flow via OAA-malate-pyruvate and acetyl-CoA-fatty acid pathways in TR

228 First, expression of the putative malate-pyruvate NADH shuttle increases in ssy5Delta cell

229 Here, we investigate the staphylococcal malate-quinone and l-lactate-quinone oxidoreductases (Mq

230 onated enzyme and a proton addition prior to malate release in the fumarate hydration reaction.

231 rom chemoreceptors that sense amino acids or malate responded to surfaces to produce c-di-GMP.

232 of mitochondria by the addition of glutamate/malate resulted in a 10-fold decrease in the ratio of ox

233 In the presence of malate, RoxS transiently escapes from repression by the

234 ALMT and AtMATE, responsible for citrate and malate secretion, respectively, were elevated under Ga s

235 atives most closely associated with sinapoyl malate showing characteristic broadening even under jet-

236 Particularly, the citrate-malate shuttle supplies cytosolic acetyl-CoA and plastid

237 racteristics brought on by the electron-rich malate side chain.

238 A significant increase in [1,4-(13)C(2)]malate signal was identified in the kidneys of mice with

239 altered as reflected by increased nighttime malate, starch, and glutathione levels and a reduced res

240 diethyl succinate were identified in vivo as malate, succinate, fumarate, and aspartate.

241 induced changes in amino acids, fumarate and malate, suggesting Krebs cycle up-regulation.

242 Malate supplementation did not extend the lifespan of lo

243 Genes encoding isocitrate lyase (aceA) and malate synthase (aceB), both involved in the carbon cons

244 We have used a fragment-based approach on malate synthase (GlcB) from Mycobacterium tuberculosis a

245 Here, we report that malate synthase (MS), the second enzyme of the glyoxylat

246 lidated the increase in isocitrate lyase and malate synthase activities.

247 as an essential physiologic function of Mtb malate synthase and advances its validation as a target

248 tudy the genes encoding isocitrate lyase and malate synthase from Chlorogloeopsis fritschii PCC 9212

249 g pathway of an 82-kDa slow folding protein, malate synthase G (MSG), was investigated.

250 anscript abundances for isocitrate lyase and malate synthase increased, and C. fritschii grew faster,

251 Our results suggest that the malate synthase reaction is a bottleneck for growth on C

252 When the genes encoding isocitrate lyase and malate synthase were expressed in Synechococcus sp. PCC

253 glyoxylate shunt genes (isocitrate lyase and malate synthase) was >300-fold higher in the light--but

254 orted the activities of isocitrate lyase and malate synthase, the key enzymes of the glyoxylate cycle

255 n metabolism, specifically isocitrate lyase, malate synthase, transaldolase, fructose bisphosphatase

256 yoxylate cycle this reaction is catalyzed by malate synthase, whereas in the ethylmalonyl-CoA pathway

257 Malate synthases are best known for their established ro

258 showed a stronger interaction with dianionic malate than with the trianionic citrate or isocitrate, s

259 ety of carbon sources, with the exception of malate, the most oxidized substrate used, resulted in ni

260 Malate, the tricarboxylic acid (TCA) cycle metabolite, i

261 conversion of hyperpolarized oxaloacetate to malate, the two signal components are separated into com

262 e and glutamate and malate dehydrogenase and malate, there are no links between single enzyme activit

263 in hydroponics but, when combined with 1 mm malate, this concentration inhibited growth.

264 malate dehydrogenase (MDH) to reduce OAA to malate, thus regenerating the electron acceptor NADP.

265 the malic enzyme (ME) pathway, which allows malate to be used as a supplemental carbon source for gr

266 (transfer of hydroxycinnamoyl moieties from malate to CoA) by HCT2 was observed with p-coumaroyl-mal

267 H), which is essential for the conversion of malate to oxaloacetate as part of the proper functioning

268 carboxylases that catalyse the conversion of malate to pyruvate and are essential for NADPH regenerat

269 carboxylating malic dehydrogenase to convert malate to pyruvate and to convert NADP(+) to NADPH; the

270 fumarate with a progressive increase in the malate-to-fumarate (MA/FA) ratio at days 2 to 5 after so

271 This study reveals new links between malate transport and mineral nutrition.

272 Vacuolar malate transport has been characterized at the molecular

273 anion flux through plant aluminium-activated malate transporter (ALMT) proteins is activated by anion

274 Triticum aestivum aluminum-activated malate transporter (TaALMT1) is the founding member of a

275 RHIZOTOXICITY (STOP1) and ALUMINUM ACTIVATED MALATE TRANSPORTER 1 (ALMT1), represent a critical check

276 ophosphate dikinase, and the 2'-oxoglutarate/malate transporter are expressed in oat and generate tra

277 m genes, including carbonic anhydrases and a malate transporter.

278 xpression of AtALMT1, which encodes the root malate transporter.

279 nts degradation of the yflS mRNA, encoding a malate transporter.

280 ic acid (MA) transporter (ALUMINUM-ACTIVATED MALATE TRANSPORTER1 [ALMT1]) expression leading to incre

281 unction analysis is shown using the aluminum malate transporter1 gene.

282 identification of ALMT4 (ALUMINUM ACTIVATED MALATE TRANSPORTER4) as an Arabidopsis thaliana ion chan

283 Aluminum-activated malate transporters (ALMTs) form a family of anion chann

284 The aluminum-activated malate transporters (ALMTs) form a membrane protein fami

285 Aluminum-activated malate transporters (ALMTs) form an important family of

286 of plastid-cytosol and mitochondrion-cytosol malate transporters in recycling the ammonia liberated d

287 Furthermore, malate uptake and utilization contribute to the adaptive

288 o S. pyogenes' carbon source repertory, that malate utilization is a highly regulated process, and th

289 Additionally, malate utilization requires the PTS transporter EI enzym

290 s suggest that other mechanisms, such as the malate valve and the Mehler reaction, were able to maint

291 ence was seen, however, for a restriction to malate valve capacity, with decreases in NADP-malate deh

292 glucose, fructose, sucrose, starch, citrate, malate, vitamin C and soluble and insoluble oxalic acid.

293 No such increase in renal [1,4-(13)C(2)]malate was observed in mice with acute GN.

294 much more effective chelator of Al(3+) than malate, we used a promoter-swap strategy to test whether

295 ntration, in the presence of L-carnitine and malate, were performed.

296 n 2-day hypoxia and is mediated by cytosolic malate whereas in 10-day hypoxia the rewiring is mediate

297 o the active mechanism intrinsic to sinapoyl malate, which is tentatively attributed to mixing of the

298 ich a reducing equivalent is transported via malate, which when oxidized to oxaloacetate, transfers a

299 er, our results indicate that MDH1 generates malate with carbons derived from glutamine, thus enablin

300 p. palustris, grew photoheterotrophically on malate without electron acceptors or H2 production.