ライフサイエンスコーパス: malate dehydrogenase

1 o-overexpression of Mdh1p, the mitochondrial malate dehydrogenase.

2 om the fusion protein with the mitochondrial malate dehydrogenase.

3 rogenase, and citrate synthase and cytosolic malate dehydrogenase.

4 recipitate of citrate synthase and cytosolic malate dehydrogenase.

5 ction between citrate synthase and cytosolic malate dehydrogenase.

6 coli alkaline phosphatase and mitochondrial malate dehydrogenase.

7 equilibrium for glycogen phosphorylase A and malate dehydrogenase.

8 hose substrates include the short-lived Mdh2 malate dehydrogenase.

9 nzymes with multiple isoforms, aconitase and malate dehydrogenase.

10 7998, which encodes a putative mitochondrial malate dehydrogenase.

11 ion of phosphoenolpyruvate carboxylase and L-malate dehydrogenase.

12 e heat-labile proteins, citrate synthase and malate dehydrogenase.

13 e of functional groups at the active site of malate dehydrogenase.

14 as activated primary T cells, that cytosolic malate dehydrogenase 1 (MDH1) is an alternative to LDH a

15 X5 (PEX5C) receptor construct or peroxisomal malate dehydrogenase 1 (pMDH1) cargo protein into sunflo

16 Malate dehydrogenase 1 and malic enzyme 1, enzymes that

17 om novel variants of muscle pyruvate kinase, malate dehydrogenase 1, glyceraldehyde-3-phosphate dehyd

18 % ZL islets): increased V(max) of PC (160%), malate dehydrogenase (170%), and malic enzyme (275%); el

19 ys, fructose-1,6-bisphosphatase (FBPase) and malate dehydrogenase 2 are degraded in the vacuole via t

20 Both FBPase and malate dehydrogenase 2 were associated with actin patche

21 es with isolated lactate dehydrogenase-1 and malate dehydrogenase-2 revealed that generation of 2-HG

22 beta-oxidation system as well as peroxisomal malate dehydrogenase 3 and carnitine acetyltransferase.

23 cinate dehydrogenase (complex II) (+44%) and malate dehydrogenase (+54%) were increased (p < 0.01).

24 within the mitochondria bind this molecule: malate dehydrogenase, a member of Krebs cycle, and adeno

25 led to increased nitrogen assimilation, NADP-malate dehydrogenase activation, and light vulnerability

26 alate valve capacity, with decreases in NADP-malate dehydrogenase activity (but not protein levels) a

27 ne [IM]) contained less than 1% of the total malate dehydrogenase activity (soluble marker), indicati

28 ys using liver extract revealed up-regulated malate dehydrogenase activity, but not aspartate transam

29 han TaHsp17.8C-II in preventing heat-induced malate dehydrogenase aggregation.

30 This is also close to the potential of NADPH-malate dehydrogenase, an enzyme known to be regulated by

31 Mitochondrial malate dehydrogenase and citrate synthase are sequential

32 nd fumarase mutants, and diminished again in malate dehydrogenase and citrate synthase mutants.

33 Channeling of oxaloacetate in the malate dehydrogenase and citrate synthase-coupled system

34 n into two target proteins (Escherichia coli malate dehydrogenase and human histone H3) caused homoge

35 alanine amino transferase and glutamate and malate dehydrogenase and malate, there are no links betw

36 ized recombinant sorghum leaf NADP-dependent malate dehydrogenase and oxidized spinach chloroplastic

37 sgenic plants using nodule-enhanced forms of malate dehydrogenase and phosphoenolpyruvate carboxylase

38 phate synthase and chloroplast stromal NADPH-malate dehydrogenase and pyruvate, Pi dikinase.

39 processed precursor forms of precursor yeast malate dehydrogenase and rat liver pALDH also were degra

40 ome targeting signal (PTS2) from peroxisomal malate dehydrogenase and reduced accumulation of 3-ketoa

41 show here, however, that for the folding of malate dehydrogenase and Rubisco there is also an absolu

42 cleotidyl cyclases, protein kinases, lactate/malate dehydrogenases and trypsin-like serine proteases.

43 ctor protein (SteA), and a metabolic enzyme (malate dehydrogenase), and demonstrate practical applica

44 on enzymes, (cytochrome c, cytochrome b, and malate dehydrogenase), and genes important in glycolysis

45 ycle components, including citrate synthase, malate dehydrogenase, and aconitase, resulted in a one-c

46 ing citrate synthase, lactate dehydrogenase, malate dehydrogenase, and aldolase.

47 uding adenosine triphosphate (ATP) synthase, malate dehydrogenase, and calretinin.

48 itates of citrate synthase and mitochondrial malate dehydrogenase, and citrate synthase and cytosolic

49 -tubulin, histone H2b, ribosomal protein S4, malate dehydrogenase, and elongation factor 2, as well a

50 onitase, isocitrate dehydrogenase, fumarase, malate dehydrogenase, and succinate dehydrogenase, but n

51 lyl versus adenylyl cyclases, lactate versus malate dehydrogenases, and trypsin versus chymotrypsin.

52 of the malate-aspartate NADH shuttle (Mdh1 [malate dehydrogenase] and Aat1 [aspartate amino transfer

53 Using malate dehydrogenase as a substrate, TaHsp16.9C-I was sh

54 etolase of the nonoxidative pentose pathway, malate dehydrogenase, asparagine synthetase, and histidi

55 nzymes such as transaldolase, transketolase, malate dehydrogenase, asparagine synthetase, and histidi

56 s for the extreme discrimination achieved by malate dehydrogenases between a variety of closely relat

57 ino acids of the N terminus of mitochondrial malate dehydrogenase bound to mitochondria, but unlike u

58 roEL-GroES-dependent substrates, Rubisco and malate dehydrogenase, but at rates slower than the cis r

59 ise interact only weakly with NADP-dependent malate dehydrogenase, but the apparent second-order rate

60 ial citrate synthase and yeast mitochondrial malate dehydrogenase channels oxaloacetate between the a

61 A Bacillus subtilis gene for malate dehydrogenase (citH) was found downstream of gene

62 d interfacial residues between mitochondrial malate dehydrogenase, citrate synthase, and aconitase we

63 iants of SR1, in the rescue of mitochondrial malate dehydrogenase, citrate synthase, and Rubisco, are

64 us of four tricarboxylic acid cycle enzymes: malate dehydrogenase, citrate synthase, isocitrate dehyd

65 equence analysis identified p36 as cytosolic malate dehydrogenase (cMDH).

66 ate that AIP 37/6 is an isoform of cytosolic malate dehydrogenase (cMDH; approximately 36.3 kDa; pI a

67 aralogous isoforms (paralogues) of cytosolic malate dehydrogenase (cMDH; EC 1.1.1.37; NAD+: malate ox

68 The lactate and malate dehydrogenases comprise a complex protein superfa

69 cytochrome-C) and others (creatine kinase M, malate dehydrogenase cytosolic, fibrinogen and parvalbum

70 of the large, leaderless, multimeric protein malate dehydrogenase did not lead to extracellular accum

71 he transcript encoding the cytosolic form of malate dehydrogenase displayed prominent drug-associated

72 re reports, the activation of NADP-dependent malate dehydrogenase does not display rate saturation ki

73 rcine citrate synthase and porcine cytosolic malate dehydrogenase does not exhibit any channeling of

74 Escherichia coli malate dehydrogenase (EcMDH) and its eukaryotic counterp

75 Five positions in the Escherichia coli malate dehydrogenase (eMDH) sequence, which distinguish

76 We report that a 1.6-fold increase in malate dehydrogenase enzyme specific activity in root ti

77 Codisruption of NDH1 and genes encoding malate dehydrogenases essentially eliminates growth on n

78 Model substrates firefly luciferase and malate dehydrogenase form strong contacts with multiple

79 Malate dehydrogenase from Escherichia coli is highly spe

80 milar analysis carried out on the tetrameric malate dehydrogenase from H. marismortui.

81 the release of cytochrome c, the release of malate dehydrogenase from the mitochondrial matrix, the

82 space to the cytosol; and (c) the release of malate dehydrogenase from the mitochondrial matrix.

83 It protected citrate synthase and malate dehydrogenase from thermal aggregation and inacti

84 the second case, that of a citrate synthase-malate dehydrogenase fusion protein, a transfer efficien

85 Two putative malate dehydrogenase genes, MJ1425 and MJ0490, from Meth

86 lanine dehydrogenase, lactate dehydrogenase, malate dehydrogenase, glutamine transaminase K, aspartat

87 CD spectroscopy reveals that mitochondrial malate dehydrogenase in 3M guanidinium chloride shows li

88 result of the participation of mitochondrial malate dehydrogenase in both citrate cycle and malate sh

89 cipitated citrate synthase and mitochondrial malate dehydrogenase in polyethylene glycol was used at

90 HG is generated by lactate dehydrogenase and malate dehydrogenase in response to hypoxia.

91 Partially folded malate dehydrogenase is devoid of catalytic activity.

92 he activity of a non-Fe-S-containing enzyme (malate dehydrogenase) is unaffected.

93 uch as fructose-1,6-bisphosphatase (FBPase), malate dehydrogenase, isocitrate lyase, and phosphoenolp

94 6.9, and the heat-denatured model substrates malate dehydrogenase (MDH) and firefly luciferase.

95 sHSP from pea, prevented the aggregation of malate dehydrogenase (MDH) and glyceraldehyde-3-phosphat

96 c(1) complex was identified as mitochondrial malate dehydrogenase (MDH) by matrix-assisted laser deso

97 The kinetics of malate dehydrogenase (MDH) catalyzed oxidation/reduction

98 Malate dehydrogenase (MDH) catalyzes the readily reversi

99 Malate dehydrogenase (MDH) from Escherichia coli is high

100 The evolutionary history of the malate dehydrogenase (MDH) gene family [NAD-dependent MD

101 sequence and phylogenetic relationships of a malate dehydrogenase (MDH) gene from the amitochondriate

102 lus HB27 strain was constructed in which the malate dehydrogenase (mdh) gene was deleted.

103 ne dinucleotide phosphate- (NADP-) dependent malate dehydrogenase (MDH) in the wild-type enzyme and i

104 Two cytosolic malate dehydrogenase (MDH) isozymes have different spati

105 Malate dehydrogenase (MDH) may be important in carbohydr

106 to be more closely related to the cytosolic malate dehydrogenase (MDH) of the same species than to a

107 Two isoenzymes of malate dehydrogenase (MDH) operate as components of the

108 s, firefly luciferase, citrate synthase, and malate dehydrogenase (MDH) provide new insights into sHS

109 fusion protein of citrate synthase (CS) and malate dehydrogenase (MDH) to assess the chances of oxal

110 hosphate, reduced are used by NADP-dependent malate dehydrogenase (MDH) to reduce OAA to malate, thus

111 oxaloacetate from one of the active sites of malate dehydrogenase (MDH) to the active sites of citrat

112 Malate dehydrogenase (MDH), a key enzyme in the tricarbo

113 ter effect does not extend to the subunit of malate dehydrogenase (MDH), also 33 kDa.

114 For the chaperonin substrates, rhodanese, malate dehydrogenase (MDH), and glutamine synthetase (GS

115 s TCA cycle enzymes from yeast mitochondrial malate dehydrogenase (MDH), citrate synthase (CS), and a

116 set of GroEL binary complexes with nonnative malate dehydrogenase (MDH), imaged by cryo-electron micr

117 MDH2 encodes mitochondrial malate dehydrogenase (MDH), which is essential for the c

118 coli aspartate aminotransferase (AATase) and malate dehydrogenase (MDH).

119 ate and oxaloacetate catalyzed by the enzyme malate dehydrogenase (MDH).

120 tamate oxaloacetate transaminases (GOT), and malate dehydrogenases (MDH).

121 phosphate dehydrogenase (Gpdh) and cytosolic malate dehydrogenase (Mdh1) genotype activity on adult t

122 hese two isoenzymes as well as mitochondrial malate dehydrogenase, Mdh1p, and have shown that Cit2p w

123 uncated form (deltanMDH2) of yeast cytosolic malate dehydrogenase (MDH2) lacking 12 residues on the a

124 Another gluconeogenic enzyme malate dehydrogenase (MDH2) showed the same degradation

125 peroxisomal NADH is reoxidised to NAD(+) by malate dehydrogenase (Mdh3p) and reduction equivalents a

126 Similarly, nine out of ten malate dehydrogenases (MDHs) selected had an arginine re

127 Mitochondrial malate dehydrogenase (mMDH) folds more rapidly in the pr

128 Mitochondrial malate dehydrogenase (mMDH; EC 1.1.1.37) has multiple ro

129 found in the nuclear gene for mitochondrial malate dehydrogenase (mMDH; EC 1.1.1.37) in the living i

130 t and dithiothreitol-denatured mitochondrial malate dehydrogenase (mtMDH), a reaction that normally r

131 l enzymes: beta-lactamase, chymotrypsin, and malate dehydrogenase, none of which are considered targe

132 n between citrate synthase and mitochondrial malate dehydrogenase occurred but no interaction between

133 growth on D-malate as a carbon source, the D-malate dehydrogenase of Escherichia coli (EcDmlA) natura

134 s: NADH dehydrogenase and the NADH-dependent malate dehydrogenase of the M. tuberculosis complex.

135 pig heart citrate synthase and mitochondrial malate dehydrogenase or cytosolic malate dehydrogenase w

136 But in the presence of bound malate dehydrogenase or rhodanese, whereas similar rapid

137 ation with two stringent substrate proteins, malate dehydrogenase or Rubisco, required a minimum of t

138 nge activities against Plasmodium falciparum malate dehydrogenase (pfMDH), which may fill the role of

139 determine the function of peroxisomal NAD(+)-malate dehydrogenase (PMDH) in fatty acid beta-oxidation

140 ted by the production of NADH by peroxisomal malate dehydrogenase (PMDH).

141 ukaryotic counterpart, porcine mitochondrial malate dehydrogenase (PmMDH), are highly homologous prot

142 oacetate with citrate synthase-mitochondrial malate dehydrogenase precipitate was inefficient at high

143 re found to function to different degrees as malate dehydrogenases, reducing oxalacetate to (S)-malat

144 mdh encoding aspartate aminotransferase and malate dehydrogenase, respectively, flank era in F. tula

145 nd MDH2 encoding mitochondrial and cytosolic malate dehydrogenases, respectively; and (iv) GLN1 encod

146 is about one-third as efficient as the best malate dehydrogenase selected, whilst the latter had abo

147 del of the fusion protein with the cytosolic malate dehydrogenase shows no clear positive electrostat

148 Malate dehydrogenase specifically oxidizes malate to oxa

149 The heat-denatured malate dehydrogenase that did not refold by the assistan

150 ption of few outlier loci (notably mtDNA and malate dehydrogenase), the positions and slopes of Fundu

151 trate channeling (e.g., of oxaloacetate from malate dehydrogenase to citrate synthase), and use of al

152 in refolding guanidine hydrochloride-treated malate dehydrogenase to its native state.

153 Binding of denatured mitochondrial malate dehydrogenase to the apical domain of GroEL cause

154 in 2), and energy metabolism (alpha-enolase, malate dehydrogenase, triosephosphate isomerase, and F1

155 By this mechanism, malate dehydrogenase uses charge balancing to achieve fi

156 complex formed by thioredoxin and monomeric malate dehydrogenase was detected by SDS/PAGE.

157 s more resistant (K(i)(app) = 6 micrometer), malate dehydrogenase was unaffected, and succinate dehyd

158 itochondrial enzymes of citrate synthase and malate dehydrogenase was used, showing that a positive e

159 of yeast aldehyde dehydrogenase (pALDH) and malate dehydrogenase were mutated so that they would not

160 ochondrial malate dehydrogenase or cytosolic malate dehydrogenase were studied using the frontal anal

161 eins, Rv1265, Rv2971, GroEL2, PE_PGRS6a, and malate dehydrogenase, were identified from BCG by mass s

162 d two key enzymes-glycerol dehydrogenase and malate dehydrogenase-were overexpressed to improve PA ti

163 acetic acid was coupled to NADH formation by malate dehydrogenase, which allowed the rates of both in

164 The activation state of malate dehydrogenase, which reflects reduced thioredoxin

165 recognizes partially folded intermediates of malate dehydrogenase with a dissociation constant of 6 m

166 eractions of mitochondrial but not cytosolic malate dehydrogenase with citrate synthase.

167 t and dithiothreitol-denatured mitochondrial malate dehydrogenase with great efficiency.

168 rase and further oxidized to oxaloacetate by malate dehydrogenase with the accompanying reduction of

169 of a ternary complex of porcine cytoplasmic malate dehydrogenase with the alternative substrate alph