ライフサイエンスコーパス: male infertility

1 could apply to treatment of disease such as male infertility.

2 d severe differentiation defects, leading to male infertility.

3 oxiredoxins (PRDXs) is associated with human male infertility.

4 ian families segregating autosomal-recessive male infertility.

5 eiotic division, resulting in cell death and male infertility.

6 t lack of Spem1 causes sperm deformation and male infertility.

7 ccumulation of mucus in the sinus cavity and male infertility.

8 iple components of capacitation resulting in male infertility.

9 d decreased motility, resulting in selective male infertility.

10 o-pulmonary disease, laterality defects, and male infertility.

11 er and viability) and increased incidence of male infertility.

12 ophthalmoparesis (SANDO), Parkinsonism, and male infertility.

13 ents that disrupt its activity could lead to male infertility.

14 CCP5 deficiency does cause male infertility.

15 s for another type of skeletal dysplasia and male infertility.

16 hagun, that is affected by both dwarfism and male infertility.

17 A number of recessive autosomal genes cause male infertility.

18 al examination are essential in diagnosis of male infertility.

19 the long arm of the human Y chromosome cause male infertility.

20 s a rare but surgically correctable cause of male infertility.

21 exclusively in the testis and implicated in male infertility.

22 culatory duct obstruction is a rare cause of male infertility.

23 lications for neurodegenerative diseases and male infertility.

24 ociated with human neurological problems and male infertility.

25 ent and our understanding of the etiology of male infertility.

26 genetic defects are directly responsible for male infertility.

27 receptors may be useful in the treatment of male infertility.

28 implications for the understanding of human male infertility.

29 ate cancer, benign prostatic hyperplasia and male infertility.

30 contribute to some forms of human idiopathic male infertility.

31 f spermatogenesis are common causes of human male infertility.

32 gulating this process might help in treating male infertility.

33 era of considerable improvements in treating male infertility.

34 mosome gene, are an important cause of human male infertility.

35 low blood pressure, kidney dysfunctions, and male infertility.

36 ated using a retroviral gene-trap system for male infertility.

37 pancreatitis resemble those associated with male infertility.

38 eficiency and identifies a treatable form of male infertility.

39 like autosomal) genes may be determinants of male infertility.

40 n some familial cases of autosomal recessive male infertility.

41 provide a candidate locus for some cases of male infertility.

42 disease progression and link SMN to general male infertility.

43 nd its loss results in neurodegeneration and male infertility.

44 drogen receptor gene in PM cells resulted in male infertility.

45 cue sperm function in certain cases of human male infertility.

46 s ranging from a lack of testis formation to male infertility.

47 h causes a number of side effects, including male infertility.

48 found that deletion of Mkrn2 in mice led to male infertility.

49 s meiotic recombination, leading to profound male infertility.

50 ns for the diagnosis and management of human male infertility.

51 t STAG3 is a strong candidate gene for human male infertility.

52 uld hypothesized its putative involvement in male infertility.

53 linical biomarker and therapeutic target for male infertility.

54 Oligo- and azoospermia are severe forms of male infertility.

55 and testicular macrophages that may lead to male infertility.

56 xic to the maturing spermatozoa resulting in male infertility.

57 it is a candidate to exert a causal role in male infertility.

58 evel in spermatozoa could be used to predict male infertility.

59 ronic airway disease, laterality defects and male infertility.

60 as a diagnostic marker for the evaluation of male infertility.

61 ized by recurrent respiratory infections and male infertility.

62 ause of defective sperm function in cases of male infertility.

63 pe resulting from deletion of Ppp1cc gene is male infertility.

64 ERalpha AF-1 is capable of rescuing AF2ERKI male infertility.

65 underlying cause of many cases of idiopathic male infertility.

66 o undergo normal differentiation, leading to male infertility.

67 including obesity, retinal degeneration and male infertility.

68 ntegration into microsurgical procedures for male infertility.

69 of the first meiotic division, resulting in male infertility.

70 luences 4.1G function and is associated with male infertility.

71 f 4.1G in B6-129 hybrids was associated with male infertility.

72 Catpser3; depletion of late spermatids; and male infertility.

73 n, central nervous system abnormalities, and male infertility.

74 for loss of some of these proteins in human male infertility.

75 ance of the abnormal DNA repair mechanism in male infertility.

76 Male infertility, a common barrier that prevents success

77 is, and mice with inactivated Pde11a exhibit male infertility, a known testicular germ cell tumor (TG

78 Male infertility accounts for almost half of infertility

79 Male infertility, affecting as many as 10% of the adult

80 transposons, followed by cell death, causing male infertility and a complete block of spermatogenesis

81 Studies of the association between male infertility and CaP are inconsistent.

82 and (iii) establishes a model for studies of male infertility and contraception.

83 Loss of ADAM3 is strongly associated with male infertility and is observed in knockouts of male ge

84 ASE), concentrating on those associated with male infertility and neuropathology.

85 njection has revolutionized the treatment of male infertility and offers an alternative to vasectomy

86 ly, its use is expanding in the treatment of male infertility and patients with chronic testicular or

87 currently being explored in the treatment of male infertility and patients with chronic testicular pa

88 aim to identify Y specific factors governing male infertility and phenotypic sex variation.

89 out of BRD7 (BRD7(-/-)) resulted in complete male infertility and spermatogenesis defects, including

90 se data demonstrate that BRD7 is involved in male infertility and spermatogenesis in mice, and BRD7 d

91 ignificant opportunity to identify causes of male infertility and targets for male contraceptives.

92 implications for common diseases, including male infertility and testicular cancer, due to abnormali

93 ding raises the possibility for treatment of male infertility and testosterone deficiency through the

94 vitro fertilization techniques for treating male infertility and whole-animal cloning by nuclear tra

95 unction, including retinopathy, renal cysts, male infertility, and a deficit in olfaction.

96 y, and is also associated with pancreatitis, male infertility, and cachexia, features characteristic

97 t subregions of the epididymis, for treating male infertility, and for generating novel methods of ma

98 ed to examine spermatogenic defects, correct male infertility, and generate transgenic animals.

99 phenotypes, including retinal degeneration, male infertility, and increased body fat.

100 pertrophic cardiomyopathy to muscle wasting, male infertility, and mental retardation, yet recent rep

101 ice have PCD characterized by hydrocephalus, male infertility, and mucus accumulation.

102 n phenotype, including retinal degeneration, male infertility, and obesity.

103 ile cilia lead to chronic airway infections, male infertility, and situs abnormalities.

104 In mice and humans, growth insufficiency and male infertility are common disorders that are genetical

105 Many cases of male infertility are diagnosed as idiopathic, reflecting

106 The genetic etiologies of idiopathic male infertility are unknown, partly due to lack of simp

107 transcription and how this relates to human male infertility are unknown.

108 reduction in H3.3 histone levels, leading to male infertility, as well as abnormal sperm and testes m

109 f the sNHE gene in mice resulted in absolute male infertility associated with a complete loss of sper

110 elopment as demonstrated by the incidence of male infertility associated with abnormal sperm ad shapi

111 ressors, which might play important roles in male infertility associated with cryptorchidism.

112 AMHCre and Rosa26CreERT2 lines) resulted in male infertility, atrophic testes with vacuolation, azoo

113 that genetic ablation ofCul4ain mice led to male infertility because of aberrant meiotic progression

114 soform, but not p53 or DeltaNp73, results in male infertility because of severe impairment of spermat

115 olism have been widely implicated in causing male infertility, but there has been little progress in

116 rm injection revolutionized the treatment of male infertility by requiring a minimal number of sperm

117 rove further reproductive research and treat male infertility by using natural plant extracts.

118 Heritable forms of nonsyndromic male infertility can arise from single-gene defects as w

119 owledge about the genetic aetiology of human male infertility can be expanded.

120 ant, but not directly translatable, to human male infertility cases.

121 ormal sense of smell, is a treatable form of male infertility caused by a congenital defect in the se

122 dy provided insights into a new mechanism of male infertility caused by the MKRN2 downregulation.

123 These results suggest that male infertility caused by thermal insult is at least pa

124 Mice that are nullizygous for Sbf1 exhibit male infertility characterized by azoospermia.

125 ame time, the TAM treatment reversed AF2ERKI male infertility compared with the vehicle-treated group

126 ociations between occupational exposures and male infertility could be identified in this study.

127 sp1 results in elevated perinatal lethality, male infertility, crosslinker hypersensitivity, and an F

128 Germ cell-specific deletion of Cul4bled to male infertility, despite normal testicular morphology a

129 wildlife and plants and have been linked to male infertility disorders in humans.

130 m but show defects in growth after birth and male infertility due to a block in spermatogenesis.

131 ermined TG repeat number in 98 patients with male infertility due to congenital absence of the vas de

132 ull-length transcript is sufficient to cause male infertility due to congenital bilateral absence of

133 been shown to cause cystic fibrosis (CF) and male infertility due to congenital bilateral absence of

134 wn that targeted mutagenesis of Bmp8b causes male infertility due to germ cell degeneration.

135 have application for treating some cases of male infertility (e.g., secondary to gonadotoxic therapy

136 pleiotropic, also resulting in sparse hair, male infertility, failure to thrive, and hydrocephaly, t

137 Poor sperm motility is a common cause of male infertility for which there are no empirical therap

138 upported by their homology with a Drosophila male infertility gene boule and sterility of Daz11 knock

139 ospermia, and its homology with a Drosophila male infertility gene boule.

140 cally, bs mice exhibit nuclear cataracts and male infertility; genetic analyses assigned the bs locus

141 In epidemiological studies, male infertility has shown an association with TGCT that

142 and is commonly characterized by sinusitis, male infertility, hydrocephalus, and situs inversus.

143 H2AX-/- mice, including growth retardation, male infertility, immune defects, chromosome instability

144 Male infertility impacts a substantial proportion of men

145 s of HNRNPGT could, therefore, be a cause of male infertility in humans.

146 und in globozoospermia, one of the causes of male infertility in humans.

147 As more gene mutations causing male infertility in mice become known, there are improvi

148 to defective sperm chromatin compaction and male infertility in mice, mirroring the observation of l

149 cell proliferation, and subsequently led to male infertility in mice.

150 et mRNAs and inactivation of Alkbh5 leads to male infertility in mice.

151 deletion of either of those channels confers male infertility in mice.

152 lls (azoospermia), which is a major cause of male infertility in the human population.

153 ormal chromosome segregation, and leading to male infertility in the patient.

154 have application for treating some cases of male infertility, including those caused by chemotherapy

155 Male infertility is a long-standing enigma of significan

156 Male infertility is associated with a loss in spermatocy

157 The association between varicocele and male infertility is well established.

158 e has been identified as causative for human male infertility, male mice deficient for members of the

159 insights on some of the potential causes of male infertility, new underlining molecular mechanisms s

160 ith a severe CFTR mutation, 5T can result in male infertility, nonclassic cystic fibrosis, or a norma

161 This result could not be attributed to male infertility nor to lack of sexual receptivity in ma

162 The biggest improvement in the management of male infertility over the past 10 years has been the int

163 n specific stimulation, could participate in male infertility pathogenesis via inflammatory cytokine

164 3-positive spermatozoa) were found in 51% of male infertility patients (n = 72), in 20% of men from c

165 dicated urologic evaluation and care for all male infertility patients.

166 This male infertility phenotype resulted from a combination o

167 for a vinclozolin-induced transgenerational male infertility phenotype.

168 n humans, ALOX15 inhibitors might counteract male infertility related to GPX4 deficiency.

169 ic and postmeiotic development, resulting in male infertility resembling oligoasthenoteratozoospermia

170 the most proximal region of the epididymis, male infertility results.

171 ngers of transmitting traits responsible for male infertility, sex and autosomal chromosome aberratio

172 Tpst2-deficient mice have male infertility, sperm motility defects, and possible a

173 te that the ERalpha AF-2 mutation results in male infertility, suggesting that the AF-1 is regulated

174 nction and could serve as a novel target for male infertility therapies.

175 With the exception of male infertility, these phenotypes are not caused by a c

176 intracytoplasmic sperm injection (ICSI) for male infertility was used and whether embryos were fresh

177 her RHOX cluster methylation associates with male infertility, we evaluated the methylation status of

178 hat mutations in CFTR are a leading cause of male infertility, we propose that defective ATP signalli

179 resulting accumulation of GlcCer results in male infertility, whereas mutations in the GBA1 gene and

180 ndrial morphology, synaptic dysfunction, and male infertility, which are features often observed in h

181 iral vectors can be used for gene therapy of male infertility without the risk of germ-line transmiss