ライフサイエンスコーパス: male mice

1 e in a mouse model of AD (APPswe/PS1DeltaE9, male mice).

2 emyelination failure in the cuprizone model (male mice).

3 l, lysolecithin-demyelinated lesion in adult male mice.

4 d 10 weeks of age) on sleep-wake behavior in male mice.

5 ng cuprizone-induced demyelinated lesions in male mice.

6 operties of SC cells of head-fixed and alert male mice.

7 isual cortical development and plasticity in male mice.

8 M2 gene promoters than did macrophages from male mice.

9 g, recall, generalization, and extinction in male mice.

10 ation in pericontusional cortex after TBI in male mice.

11 ity than conventional soybean oil in C57BL/6 male mice.

12 anteromedial BNST in female mice but not in male mice.

13 tigate the failure to ensure COs in juvenile male mice.

14 lters specific motor functions of 1-year-old male mice.

15 nt ameliorated TFH cells and GC responses in male mice.

16 c-fos colocalizations in female mice but not male mice.

17 rmatozoa number in the third generation (F3) male mice.

18 mpaired exploratory behavior in Mecp2(308/y) male mice.

19 therapeutic LPS-induced ALI model in C57BL/6 male mice.

20 ys and regulation of Egfr between female and male mice.

21 te the expression of Egfr between female and male mice.

22 the stria terminalis of female mice but not male mice.

23 esia and priming are reduced specifically in male mice.

24 es, hypothermia, and early death seen in RTT male mice.

25 xonal swellings in 120 F2-En1+/- 17 week-old male mice.

26 ulated by exercise in BDNF Val66Met knock-in male mice.

27 had no effect on browning in young female or male mice.

28 (24 months) versus Young (4 months) C57BL/6 male mice.

29 avior and learning abilities in adult mutant male mice.

30 lung and colon tissues from both female and male mice.

31 m of how PPARalpha inhibits Th1 responses in male mice.

32 e GluN1 in dendrites of PVN neurons in adult male mice.

33 s resembled the phenotype of Tex11-deficient male mice.

34 ed renal damage and albuminuria in Cyp4a14KO male mice.

35 in DNA isolated from sperm from drug-treated male mice.

36 tion and a reduced learning ability in adult male mice.

37 Pathogen-free 8-week-old Balb/cJRj male mice.

38 on in hippocampal area CA1 in adult C57BL/6J male mice.

39 betes mellitus (DM) and were mated with lean male mice.

40 Endothelial cells and C57BL/6 male mice.

41 or Cav1.3 LTCC deficiency in 6-OHDA-treated male mice.

42 MeA markedly reduced the severity of DIO in male mice.

43 esponses were more pronounced in female than male mice.

44 e increments in LH secretion in anesthetized male mice.

45 r of OVA-specific TH17 cells from female and male mice.

46 green fluorescent protein, or Balb/c Tsg6-/- male mice.

47 (0.9% NaCl) was administered to 8-month-old male mice.

48 es median lifespan, with a greater effect in male mice.

49 -deficient mammary tumors in the fat pads of male mice.

50 female mice developed more visceral fat than male mice.

51 mbosis in vivo in lupus-prone (NZW x BXSB)F1 male mice.

52 divide significantly more frequently than in male mice.

53 ulomegaly) was observed only in CAPs-exposed male mice.

54 s associated to the metabolism of female and male mice.

55 on results in hypertension in female but not male mice.

56 s was not altered significantly in Ptchd1 KO male mice.

57 ed mice compared with saline-treated control male mice.

58 gulated corticosterone in stress-susceptible male mice.

59 ermates after 10 weeks of a high-fat diet in male mice.

60 n) and control diet in 10-month-old C57BL/6J male mice.

61 CAMK2G were altered in amygdala and mPFC of male mice.

62 bited inflammation only in gluteal muscle of male mice.

63 e effect of their acute silencing in vivo in male mice.

64 lpha7 nAChRs regulate aggressive behavior in male mice.

65 stral Re of brain slices prepared from adult male mice.

66 ment on indices of chronic diseases in adult male mice.

67 nd glucose intolerance in female rather than male mice.

68 ons in mediating susceptibility to stress in male mice.

69 d insulin resistance specifically in HFD-fed male mice.

70 al cells (MCs) in the olfactory bulb (OB) of male mice.

71 BL of adult female mice but not in the BL of male mice.

72 ctor expressing tetanus toxin light chain in male mice.

73 ring up to 100 Hz in brain slices from Swiss male mice.

74 scle, heart, kidney, and bone in female than male mice.

75 etter functional recovery in female, but not male, mice.

76 9 are highly co-localized in female, but not male, mice.

77 gastrointestinal motility in female, but not male, mice.

78 COT1 in hepatic lipid metabolism in C57Bl/6J male mice 1 week after adenovirus-mediated Acot1 knockdo

79 ly greater in PTH2R knock-out than wild-type male mice 2 and 4 weeks after a 2 s 1.5 mA footshock.

80 is period, although at 4 months mortality in male mice (47%) was substantially higher compared with f

81 l antigens were identified in 81% of K8-null male mice 8 mo or older.

82 IHC of male mice AAA aortas showed increased p308, AKT-Ser-473,

83 haracterization of the adipose tissue of the male mice after HFD challenge revealed that the mRNA lev

84 -cell mass and proliferation in 12-month-old male mice after just 2 weeks.

85 and for smaller infarct sizes in female and male mice after permanent coronary ligation.

86 d basolateral amygdala of stress-susceptible male mice after remote memory retrieval.

87 Male mice aged 8-12 wk were subjected to intestinal I/R

88 those observed in AngII-induced hypertensive male mice and may be ascribed in part to baseline diffe

89 rformed controlled cortical impact injury on male mice and determined the expression of serum amyloid

90 n female mice compared with that observed in male mice and discovered an intermediate phenotype after

91 o negatively regulate IFN-gamma responses in male mice and identified Ifng as the gene target of PPAR

92 preventing inappropriate HIF-1 activation in male mice and identifies RANTES as a novel therapeutic t

93 RNA levels of Ppm1f in amygdala and mPFC in male mice and in mPFC of female mice.

94 vitro, increased in obese/insulin resistant male mice and increased in obese/insulin-resistant human

95 those observed in AngII-induced hypertensive male mice and may be ascribed in part to baseline differ

96 rbing osteoclasts and increased bone mass in male mice and protected female mice from bone loss follo

97 uce LTB4 levels in exudates of female versus male mice and rats.

98 OT increased social interaction in stressed male mice and reduced freezing in the resident-intruder

99 which was maintained to a greater extent in male mice and was associated with greater bacterial load

100 uces comparable results to those obtained in male mice and will greatly facilitate studying female st

101 oietic stem-cell division in female, but not male, mice and attenuated the increases in haematopoieti

102 macrophages and neutrophils in the lungs of male mice, and depletion of inflammatory monocyte macrop

103 s, a major risk factor for mammary cancer in male mice, and one that would appear to be due to pfp's

104 Bmpr1b resulted in osteopenia in 8-week-old male mice, and the phenotype was transient and gender sp

105 irus (DENV), in the testis and epididymis of male mice, and this was associated with tissue injury th

106 Male mice, approximately 25 g, were gavaged with EtOH (2

107 expression levels of Egfr between female and male mice are also different.

108 Male mice are more sensitive to silica-induced lung fibr

109 In their absence, sperm does not form and male mice are sterile.

110 Prdx6 (-/-) male mice are subfertile, and the deficiency or inactiva

111 eature-negative conditioning paradigm, where male mice are trained on a trial in which a conditioned

112 Depending on whether female or male mice are used, differences in biodistribution and n

113 , revealing phenotypic changes in female and male mice associated with changes in circulating levels

114 bial fracture with intramedullary pinning in male mice, associated with cognitive deficits, we charac

115 uits of relevance to cognitive processing in male mice at 6, 24, and 72 h postsurgery.

116 , ManR mRNA, but not ASGR mRNA, decreases in male mice at the time of sexual maturation.

117 ision cut liver slices and in vivo on hybrid male mice BDF1.

118 FES PET could clearly visualize the tumor in male mice bearing a SKOV3 xenograft.

119 skin-specific androgen receptor deletion in male mice, both of which reversed the male phenotype.

120 3 replicated efficiently in the intestine of male mice but not female mice.

121 eversed the effects of stress on behavior in male mice, but effects were mixed in female mice.

122 gene 1 (PLAG1) leads to reduced fertility in male mice, but the mechanism by which PLAG1 contributes

123 Liver damage was induced in male mice by placing them on choline-deficient, ethionin

124 stemic anaphylaxis was induced in female and male mice by using histamine, as well as IgE or IgG rece

125 uronal changes in the brains of C3-deficient male mice (C3 KO) compared with age-, strain-, and gende

126 vascular responses to experimental stroke in male mice can be evaluated with wide range sensitivity f

127 onstrate here that VSG in C57BL/6J wild-type male mice can reverse these chromatin modifications and

128 This sexual dimorphism suggests that male mice cannot be used as proxies for females in pain

129 ly, deletion of one PRL1 allele in PRL2(-/-) male mice causes complete infertility.

130 Vaccinated male mice challenged with Zika virus were protected agai

131 rations in microglia were more pronounced in male mice compared with female mice.

132 l hierarchy on micturition patterns in adult male mice, confirming the existence of a micturition con

133 All studies were conducted in age-matched, male mice consuming alcohol-containing liquid diets.

134 Tumor number was significantly lower in male mice consuming red tomato diets (1.73 +/- 0.50, P =

135 ed differences was found to be testosterone: male mice could be rendered susceptible to liver inflamm

136 ruption of hepatic estrogens action in adult male mice could recapitulate aspects of the metabolic sy

137 In male mice, decreased expression of NRXN3 mRNA was observ

138 Here we show that female (not male) mice deficient in Arg-II (Arg-II(-/-)) are protect

139 Twenty five percent of Mrc1(-/-)Asgr2(-/-) male mice develop priapism when mating due to thrombosis

140 beta-cell function; a greater proportion of male mice developed CP than female mice.

141 The 12 M and 19 M+ male mice developed more cartilage erosions and thicker

142 contrast, podocyte-specific PTP1B transgenic male mice developed spontaneous proteinuria and foot pro

143 pe 1 via streptozotocin injection, Cyp4a14KO male mice developed worse renal disease than streptozoto

144 in sex-specific histologic alterations, with male mice developing urothelial hyperplasia and female m

145 In this report, we show that male mice devoid of Stag3 display a severe meiotic pheno

146 In contrast to females, HCD-fed male mice did not exhibit any fertility decline compared

147 ss 10 extended-access sessions more than A/A male mice did.

148 that they have been conducted exclusively in male mice due to the difficulty of initiating attack beh

149 ntaneous GnRH secretion in brain slices from male mice during perinatal and postnatal development usi

150 ge Esr1(+) neuronal activity in the VMHvl of male mice engaged in these social behaviours.

151 CA1 region of the hippocampus in young adult male mice, enhances neuronal excitability and improves c

152 Furthermore, G/G male mice escalated the amount of heroin self-administra

153 Optogenetic stimulation of VMHvl in male mice evokes attack toward conspecifics and inactiva

154 Ptchd1 knock-out (KO) male mice exhibit cognitive alterations, including defec

155 ateral ventricle dilation) preferentially in male mice exposed to CAPs, and it persisted through youn

156 Previously, we found that adult male mice expressing the autism-associated SERT Ala56 va

157 , we show that sperm derived from Plcz1(-/-) male mice fail to trigger Ca(2+) oscillations in eggs, c

158 insulin, glucose, and cholesterol in C57BL/6 male mice fed a high-fat diet.

159 PR30 had no significant metabolic effects in male mice fed the HFD and both sexes of mice fed a chow

160 or (ER) alpha compared with macrophages from male mice following allergen challenge.

161 by osmotic minipump to 38-week-old C57BL/6J male mice for 2 weeks.

162 Here we show that the typical preference of male mice for females is eliminated in mutants lacking o

163 c consequences of high-fat diet feeding than male mice, for reasons that are incompletely understood.

164 Male mice from 45 strains of the Collaborative Cross (CC

165 Female and male mice from the same recombinant inbred (RI) strain h

166 The right knees of eight-week old male mice from two recombinant inbred lines (LGXSM-6 and

167 Here, we used male mice genetically deficient on either uPA (uPA(-/-))

168 e examined the effects of SPP1 deficiency in male mice given 40% calories derived from ad libitum con

169 insulin and high adiponectin levels, whereas male mice had impaired glucose homeostasis, compromised

170 We found that aged isolated male mice had significantly increased infarct volume, ne

171 al obstacles, preclinical modeling of UTI in male mice has been limited.

172 In vivo studies revealed that JDP2 null male mice have normal reproductive function, as expected

173 Male mice have reduced numbers of ILC2 progenitors (ILC2

174 Surprisingly, male mice heterozygous for Gpx4_U46S presented subfertil

175 Male mice heterozygous for HDAC4(A778T) did not show any

176 Male mice, homozygous for a disrupted 5alphaR1 allele (5

177 /CA3a-restricted excitatory neurons in adult male mice impaired the persistence of long-term SRM but

178 We exposed male mice implanted with wireless telemetry transmitters

179 nths of age, induction of activated FoxM1 in male mice improved glucose homeostasis with unchanged be

180 gnificantly decreased by food deprivation in male mice in a manner that was partially reversed by the

181 tudies have shown that inhibiting miR-34a in male mice in settings of pathological cardiac hypertroph

182 d disordered brain sexual differentiation of male mice in which the kisspeptin receptor was deleted s

183 the long bones of Prkca(-/-) female but not male mice, in which bone tissue progressively invades th

184 (+/-) mice accelerates BCC carcinogenesis in male mice, in which UVR does not produce D3.

185 ocaine conditioned place preference (CPP) in male mice increased Cav1.2 L-type Ca(2+) channel mRNA an

186 Hepatic Sugp1 overexpression in CD1 male mice increased plasma cholesterol levels 20-50%.

187 duces social approach in female mice but not male mice, increased early growth response factor 1 immu

188 nsplanted cardiac MSCs from TLR4(-/-) and WT male mice into the infarcted myocardium of female WT mic

189 monstrate that overexpression of TRAF3IP2 in male mice is sufficient to induce myocardial hypertrophy

190 atory infiltrates showed that female but not male mice lacking p38alpha in myeloid cells exhibited re

191 Male mice lacking two key genes involved in Se metabolis

192 spermatogenesis and reproductive ability of male mice, likely due to functional compensation by the

193 In male mice, liver tumor burden was recently found to corr

194 nt project utilised heterogeneous stock (HS) male mice (n = 580) to investigate the genetic basis for

195 female mice and decreased social approach in male mice naive to defeat.

196 st- (F1) and second-generation (F2) C57BL/6J male mice offspring.

197 ong-term voluntary wheel-running in C57BL/6J male mice on their offspring's predisposition to insulin

198 Here, we show that, in male mice, OxtrINs regulate anxiety-related behaviors.

199 ht gain from 9.6 +/- 1.5 to 4.2 +/- 1.4 g in male mice (P < 0.001), while the weight gain in female m

200 Male mice permanently lacking 5-HT2B receptors, even res

201 The homozygous male mice present with massive loss of spermatozoa as a

202 Gestational bisphenol-A in male mice primed macrophages in adulthood and raised gra

203 ediated deletion of Esr1 in the MeA of adult male mice produced a rapid body weight gain that was ass

204 perphagia following germline loss of MC4R in male mice promotes growth while suppressing the growth h

205 activity, and decreased body growth rate in male mice raised by foster mothers that exhibit high lev

206 nance and histological study of 45 wild-type male mice randomized to doxorubicin (n=30, 5 mg/kg of do

207 Male mice received a controlled cortical impact or sham

208 Tumors developed in 72% of the male mice receiving both oncogenes plus IL-33 by 10 week

209 After puberty, male mice recover, but female corticalization is still i

210 changes in gene expression, predominantly in male mice, reflecting potential shifts in vasculature, a

211 ure miRNA-22 is more abundant in muscle from male mice relative to females and that this enables sex-

212 Additional phenotyping of male mice revealed PTSD-associated behaviors, including

213 Male mice selected for TRAV8/TRAJ52 (CATDLNTGANTGKLTFG)

214 utilized an aggression-seeking task in which male mice self-initiated aggression trials to gain brief

215 urs/day for >/=21 consecutive days) to adult male mice, several hippocampal characteristics were exam

216 Female and estrogen-treated male mice show greater resistance to pneumococcal pneumo

217 fat diet maintain CX3CL1-CX3CR1 levels while male mice show reductions in both ligand and receptor ex

218 However, PRL1(-/-)/PRL2(+/-) male mice show testicular atrophy phenotype similar to P

219 enic effects of the high fat diet, and obese male mice showed decreased locomotion activity in respon

220 ice experiencing pain (in all combinations); male mice similarly treated displayed unimpeded sexual m

221 Full blockade of IGF-1R affected female and male mice similarly.

222 mice resulted in loss of social interest in male mice specifically during the sexually receptive pha

223 th and exercise capacity in adult hemizygous male mice starting from 7 to 10 months of age.

224 ance, these changes were more pronounced for male mice than for female mice.

225 n of Cul4a results in cardiac hypertrophy in male mice that can be partially rescued by the deletion

226 We used Cyp4a14KO male mice that exhibit androgen-sensitive hypertension d

227 toantibodies were detected in aging K18-null male mice that had a related liver phenotype but normal

228 ession of fluorescent marker into the VTA of male mice that had Cre-recombinase driven by OTR gene ex

229 ulatory proteins particularly in hearts from male mice that had depressed levels of SERCA2 and phosph

230 verall these results indicate that, in adult male mice, the BDNF Val66Met polymorphism impairs the be

231 Indeed, in ovariectomized females and in male mice, the dominance of M2-like macrophages observed

232 Of 3 groups of Mus musculus Swiss male mice, the first was inoculated intramuscularly with

233 However, in male mice, the vitamin D response to UVB was attenuated

234 onversely, increasing brain CX3CL1 levels in male mice through central pharmacological administration

235 wt and AhRR Tg mice were less sensitive than male mice to acute toxicity induced by TCDD.

236 /NOD.H2(h4) female mice were more prone than male mice to developing pathogenic TSHR Abs.

237 arly from hippocampal CA1 of awake, behaving male mice to examine both subthreshold activity and spik

238 he behavioral and physiological responses of male mice to females on a moment-to-moment basis.

239 We exposed C57BL/6 male mice to graded CR (from 0 to 40%) for three months

240 Exposing male mice to nicotine or cocaine enables their male offs

241 Enhanced susceptibility of male mice to SARS-CoV was associated with elevated virus

242 the predominant form of plasticity in naive male mice, to spike-timing-dependent long-term potentiat

243 lus IL-33 by 10 weeks but in only 20% of the male mice transduced with the oncogenes alone.

244 ion and progression upon removal of MeCP2 in male mice transitions from 3 to 4 months to only several

245 Male mice underwent a unilateral (right) nephrectomy fol

246 CA1 region of the hippocampus of middle-aged male mice using a viral vector rejuvenates hippocampal f

247 In male mice, using pathway-specific retrograde tracing, wh

248 The transient decrease of body weight in male mice was accompanied by decreased fat mass.

249 GnRH neuron deficiency in male mice was accompanied by impaired testes growth, a c

250 In vivo characterization using tumor-bearing male mice was performed by PET/CT for (86)Y- 4: - 6: and

251 Further characterization of SEFL effects on male mice was performed with additional behavioral tests

252 estrogen receptor-alpha (ESR1) knockout (KO) male mice, we describe a unique SFM whose inhabitants di

253 ophysiology in juvenile-adolescent GAD67-GFP male mice, we examined excitatory plasticity in fluoresc

254 In muscle of symptomatic AR113Q male mice, we found expression upregulation of Pax-7, my

255 In freely moving male mice, we show that SOM+ cells can fire immediately

256 e transporter (VNUT)-deficient and wild-type male mice, we showed that ATP has a crucial role in urin

257 C57BL/6 male mice were administered a dose of nicotine (3, 6.3,

258 C57BL/6J male mice were administered FOS, GOS, or a combination o

259 Male mice were allowed to exercise voluntarily for 21 da

260 ic WT female mice mated with SOD1 transgenic male mice were analyzed.

261 Male mice were assigned into Fracture + Sham TBI (FX) or

262 Here, male mice were characterized as alcohol-heightened (AHAs

263 In vivo, adult C57BL/6J male mice were fed a folate-free diet for 4 weeks to ind

264 Male mice were fed a HFD (60% calories from fat) or regu

265 C57BL/6 male mice were fed a Western diet (WD) +/-75 mg PDX twic

266 Weanling C57BL/6 male mice were fed an iron-deficient (4 ppm) or iron-ade

267 Calr mcKO male mice were fertile, but fcKO female mice were steril

268 and homozygous BDNF Val66Met (BDNF(Met/Met)) male mice were housed in cages equipped with or without

269 Anxiodepressive-like behaviors in C57BL/6J male mice were induced by neuropathic pain, unpredictabl

270 o test this possibility healthy young Balb/c male mice were injected with serpin B13 mAb or IgG contr

271 Young male mice were injected with vehicle or recombinant iris

272 Here, C57BL/6-Min male mice were mated with females from 27 Collaborative

273 When ZIKV-infected male mice were mated with naive female mice, the weight

274 5alphaR1-KO male mice were more susceptible to fibrosis after CCl4 a

275 Our results showed that male mice were more susceptible to SARS-CoV infection co

276 Male mice were more vulnerable to the anxiogenic effects

277 Swiss male mice were randomly assigned to Sham-operated mice (

278 e mice developed marked cholangitis, whereas male mice were resistant to cholangitis induction.

279 C57BL6 male mice were supplemented with 8% (w/v) alcohol in wat

280 Four-day-old male mice were treated with AFB1 using a regimen that in

281 ized (OVX) female mice, and estrogen-treated male mice were treated with silica, and lung injury was

282 hree-month-old control and 24-month-old aged male mice were used.

283 ne production in the skin of female, but not male, mice when compared with infection with an isogenic

284 sufficient to promote courtship behavior in male mice, whereas robust courtship behavior can be indu

285 ved in aortic root, arch, and total aorta of male mice, whereas the effect was less pronounced and si

286 was not rescued in Jmjd3- and Utx-deficient male mice, which carry the catalytically inactive Utx ho

287 cFC) at 2 months of age in APPswe/PS1DeltaE9 male mice, which could be reversed by the actin-polymeri

288 In addition, both CD- and WD-fed FXR KO male mice, which had hepatic lymphocyte and neutrophil i

289 s induced by continuous GH infusion (cGH) in male mice, which rapidly feminizes the temporal profile

290 sticity, alters specific social behaviors in male mice, while leaving females unaffected.

291 We show that in Mecp2-deficient male mice, whisker-evoked activity is roughly topographi

292 Treating STZ-HFD male mice with 2% cholestyramine led to significant impr

293 Male mice with a deletion of a 1.1 Mb Nxf2-Nxf3 X-chromo

294 Male mice with a germline-specific deletion of Utf1 resu

295 olactin on blood pressure (BP), we generated male mice with a single-copy transgene (Tg; inserted int

296 Using male mice with germline loss of the MC4R, we assessed pu

297 We report that treatment of male mice with melphalan (MLP), a bifunctional alkylatin

298 Since hemizygous male mice with Nsdhl mutations die by midgestation, we g

299 ng induced a much higher incidence of HCC in male mice with substantially increased intrahepatic rete

300 The prostates from virgin male mice with the above four genotypes were analyzed at