ライフサイエンスコーパス: malignant brain tumor

1 Medulloblastoma is the most common pediatric malignant brain tumor.

2 a is both the most common and lethal primary malignant brain tumor.

3 HOXA9 in glioblastoma (GBM), the most common malignant brain tumor.

4 appaB signaling in combination therapies for malignant brain tumors.

5 cells remaining after surgical debulking of malignant brain tumors.

6 of this approach in patients with recurrent malignant brain tumors.

7 all central nervous system tumors and 80% of malignant brain tumors.

8 option for patients with certain benign and malignant brain tumors.

9 ance in improving survival for patients with malignant brain tumors.

10 00 in treating both adults and children with malignant brain tumors.

11 m the suggested benefit from temozolomide in malignant brain tumors.

12 en infused intratumorally into patients with malignant brain tumors.

13 of IL-13R complex in 25 primary explants of malignant brain tumors.

14 in cellular immunotherapy trials for primary malignant brain tumors.

15 llular immunotherapy trials in human primary malignant brain tumors.

16 erapy for some young children with recurrent malignant brain tumors.

17 atients with progressive growth of recurrent malignant brain tumors.

18 or experimental treatment of uniformly fatal malignant brain tumors.

19 cue (ABMR) for young patients with recurrent malignant brain tumors.

20 ft models, to determine its activity against malignant brain tumors.

21 ent antiproliferative activity against human malignant brain tumors.

22 rove the treatment outcomes of patients with malignant brain tumors.

23 lymerases, resulting in 'ultra-hypermutated' malignant brain tumors.

24 as well as diseases, including most notably malignant brain tumors.

25 receiving radiotherapy for the treatment of malignant brain tumors.

26 y contribute to the etiology of these highly malignant brain tumors.

27 that can improve management of patients with malignant brain tumors.

28 ations in the normal brain, and is common in malignant brain tumors.

29 ne therapy approaches to treat patients with malignant brain tumors.

30 ctive against a variety of tumors, including malignant brain tumors.

31 brain and that this pathway is subverted in malignant brain tumors.

32 get for new anti-invasive therapies to treat malignant brain tumors.

33 ession of the anti-bacterial gene deleted in malignant brain tumor 1 (DMBT1) is mediated by p38 and S

34 Lethal 3 malignant brain tumor 1 (L3MBTL1), a homolog of the Dros

35 Further, we find that lethal 3 malignant brain tumor 1 (L3MBTL1), a reader protein with

36 The deleted in malignant brain tumors 1 (DMBT1) gene on 10q25-26 is a c

37 ernatively spliced product of the deleted in malignant brain tumors 1 (DMBT1) gene.

38 y agglutinin [SAG, encoded by the deleted in malignant brain tumors 1 (DMBT1) gene] is an innate immu

39 sephosphate isomerase (TPI1), and deleted in malignant brain tumors 1 protein (DMBT1).

40 Dmbt1 (deleted in malignant brain tumors 1) was identified as a candidate

41 e further show that expression of Deleted in Malignant Brain Tumors 1, the human homologue of the col

42 astoma multiforme is the most common primary malignant brain tumor and despite treatment with surgery

43 Glioblastoma (GBM) is the most malignant brain tumor and is highly resistant to intensi

44 ultiforme is the most common type of primary malignant brain tumor and may arise from a cell with neu

45 GB is the most common and aggressive primary malignant brain tumor and the current standard-of-care t

46 el therapeutic strategy for the treatment of malignant brain tumors and confirm the antitumor activit

47 B opening for drug delivery in patients with malignant brain tumors and effectively facilitate BBB cl

48 treatment related morbidity in infants with malignant brain tumors and in older children with standa

49 cell surface receptors are overexpressed in malignant brain tumors and reportedly involved in tumor

50 the rationale for targeting angiogenesis in malignant brain tumors and summarizes the results of rec

51 Glioblastoma is the most common primary malignant brain tumor, and is refractory to surgical res

52 Gliomas account for 77% of primary malignant brain tumors, and the prognosis has hardly cha

53 Malignant brain tumors are highly lethal and aggressive.

54 s of glioma, the most common type of primary malignant brain tumor, are poorly understood.

55 Glioblastomas (GBMs), the most common and malignant brain tumors, are highly resistant to current

56 or in 20 patients with pathologically proven malignant brain tumors (astrocytoma, n = 17; oligodendro

57 iving acute lymphoblastic leukemia (ALL) and malignant brain tumors (BTs) have a higher incidence of

58 Glioblastoma is the most common primary malignant brain tumor, but despite multimodal treatment

59 ma multiforme, the most common adult primary malignant brain tumor, but not in grade II to III glioma

60 A significant proportion of children with malignant brain tumors can avoid radiotherapy and prolon

61 Potent immune responses against malignant brain tumors can be elicited by paracrine intr

62 el in which the spatio-temporal expansion of malignant brain tumor cells is guided by environmental h

63 TM-601 binds to malignant brain tumor cells with high affinity and does

64 Malignant brain tumors consist of a number of distinct s

65 Nervous System Lymphomas (PCNSLs) are rare, malignant brain tumors derived from lymphocytes B.

66 Diffuse malignant brain tumors develop during early embryogenesi

67 The protein deleted in malignant brain tumors (DMBT1) and the trefoil factor (T

68 ike family of proteins, often accompanied by malignant brain tumor domain (MBT) and sterile alpha mot

69 SFMBT1 belongs to the malignant brain tumor domain-containing chromatin reader

70 We present a protocol for using the triple malignant brain tumor domains of L3MBTL1 (3xMBT), which

71 BT1 (Scm [Sex comb on midleg] with four MBT [malignant brain tumor] domains 1) is a poorly characteri

72 The dismal prognosis of malignant brain tumors drives the development of new tre

73 In archival malignant brain tumors expression levels of ALK and PTN

74 omplexes, polycomb repressive complexes, and malignant brain tumor family proteins, that collectively

75 pressor protein, the product of the lethal(3)malignant brain tumor gene.

76 endent intercellular signaling of the highly malignant brain tumor glioblastoma multiforme (GBM).

77 ealed a number of miRNAs dysregulated in the malignant brain tumor glioblastoma.

78 bitors for many tumors, including the highly malignant brain tumor glioblastoma.

79 CL12 and its cognate receptor CXCR4 regulate malignant brain tumor growth and are potential chemother

80 lymphoblastic leukemia, hepatoblastoma, and malignant brain tumors had the highest risk of early dea

81 stoma (GBM), the most common type of primary malignant brain tumors harboring a subpopulation of stem

82 Glioblastoma, the most common primary malignant brain tumor, harbors a small population of tum

83 the activation of developmental programs in malignant brain tumors has emerged as a driver for growt

84 f medulloblastoma, the most common childhood malignant brain tumor: However, many long-term survivors

85 Glioblastoma is the most common malignant brain tumor in adults and carries a particular

86 ligodendrogliomas are the second most common malignant brain tumor in adults and exhibit characterist

87 glioblastoma (GBM), the most common primary malignant brain tumor in adults, remains a significant u

88 astoma is the most common and lethal primary malignant brain tumor in adults.

89 ioblastoma multiforme (GBM), the most common malignant brain tumor in adults.

90 own in glioblastoma, the most common primary malignant brain tumor in adults.

91 o medulloblastoma formation, the most common malignant brain tumor in childhood.

92 Medulloblastoma is the most common malignant brain tumor in children, and despite improveme

93 Medulloblastoma, the most common malignant brain tumor in children, is a biologically het

94 Medulloblastoma, the most common primary malignant brain tumor in children, is a radiosensitive a

95 eatment for medulloblastoma, the most common malignant brain tumor in children, remains limited to su

96 a subset of medulloblastoma, the most common malignant brain tumor in children, was found to contain

97 Medulloblastoma (MB) is the most common malignant brain tumor in children, where one-third of pa

98 leading to medulloblastoma, the most common malignant brain tumor in children.

99 Medulloblastoma is the most common malignant brain tumor in children.

100 ormation in medulloblastoma, the most common malignant brain tumor in children.

101 Medulloblastoma is the most common malignant brain tumor in children.

102 l models of medulloblastoma, the most common malignant brain tumor in children.

103 Medulloblastoma is the most common malignant brain tumor in children.

104 origin for medulloblastoma, the most common malignant brain tumor in children.

105 on promotes medulloblastoma, the most common malignant brain tumor in children.

106 nating in the cerebellum, is the most common malignant brain tumor in children.

107 ciated with medulloblastoma, the most common malignant brain tumor in children.

108 Medulloblastoma (MB) is the most common malignant brain tumor in children.

109 tly linked to medulloblastoma (MB), a common malignant brain tumor in children.

110 that collectively represent the most common malignant brain tumor in children.

111 ve rise to medulloblastomas, the most common malignant brain tumor in children.

112 Medulloblastoma is the most common malignant brain tumor in children.

113 Medulloblastoma is the most common malignant brain tumor in children.Chromosome arm 17p13.3

114 Glioblastoma is the most malignant brain tumor in humans and an average survival

115 Astrocytoma is the most common malignant brain tumor in humans.

116 Glioblastoma is the most common malignant brain tumor in humans.

117 poor prognosis, are the most common primary malignant brain tumors in adults.

118 Medulloblastoma, one of the most malignant brain tumors in children, is thought to arise

119 omprise medulloblastoma, are the most common malignant brain tumors in children.

120 otherapy resulted in a high response rate of malignant brain tumors in infants.

121 system and the efficacy of gene therapy for malignant brain tumors include: 1) the design of more ef

122 dality of therapy for all commonly occurring malignant brain tumors, including medulloblastoma and gl

123 Evaluation of treatment effects in malignant brain tumors is challenging because of the lac

124 Medulloblastoma, the most common pediatric malignant brain tumor, is an example of a disease that h

125 Glioblastoma, the most common and aggressive malignant brain tumor, is propagated by stem-like cancer

126 blastoma multiforme, the most common form of malignant brain tumor,is resistant to all forms of thera

127 gene delivery in gene therapy strategies for malignant brain tumors, it is important to determine the

128 ogue of Drosophila tumor suppressor lethal(3)malignant brain tumor (l(3)mbt), binds histones in a met

129 Lethal malignant brain tumors (lmbt) result from the loss of th

130 his mechanism persists in medulloblastoma, a malignant brain tumor markedly sensitive to radiation an

131 Malignant brain tumor (MBT) domain of PHF20L1 binds to m

132 tial recognition of p53K382me1 by the triple malignant brain tumor (MBT) repeats of the chromatin com

133 Human L3MBTL1, which contains three malignant brain tumor (MBT) repeats, binds monomethylate

134 61, which encodes a protein composed of four malignant brain tumor (MBT) repeats.

135 We demonstrate that the malignant-brain-tumor (MBT) protein L3MBTL1 is in a comp

136 Glioblastoma is the most common primary malignant brain tumor of adults and one of the most leth

137 Glioblastoma is the most common malignant brain tumor of adults and one of the most leth

138 Medulloblastoma, the most common malignant brain tumor of childhood, is believed to deriv

139 uggest that medulloblastoma, the most common malignant brain tumor of childhood, is comprised of four

140 Medulloblastoma is a common malignant brain tumor of childhood.

141 Medulloblastoma is the most common malignant brain tumor of childhood.

142 ulloblastomas (PNET/MB), are the most common malignant brain tumor of childhood.

143 Medulloblastoma (MB) is the most common malignant brain tumor of childhood.

144 Medulloblastoma (MB) is the most common malignant brain tumor of children.

145 Medulloblastomas are the most common malignant brain tumors of childhood, and despite recent

146 e blood-brain barrier (BBB) in patients with malignant brain tumors or metastases.

147 roliferation of abnormal microvasculature in malignant brain tumor patients, we have undertaken a cel

148 Malignant brain tumors pose diagnostic and therapeutic p

149 the human homolog of the Drosophila lethal(3)malignant brain tumor protein, is a member of the polyco

150 ranscriptional repressor protein, lethal (3) malignant brain tumor protein, L(3)MBT, and the histone

151 s without systemic toxicity in patients with malignant brain tumors refractory to conventional therap

152 apies, the clinical outcome of patients with malignant brain tumors remains extremely poor.

153 with Glioblastoma Multiforme (GM), a highly malignant brain tumor, remains poor despite concerted ef

154 It contains two MBT (malignant brain tumor) repeats; the MBT is a protein mod

155 Gliomas, the most common malignant brain tumors, represent the main focus of the

156 Mutations in any of three genes [l(3)malignant brain tumor, shackleton, and out of sync] affe

157 TB) is a major obstacle for drug delivery to malignant brain tumors such as glioblastoma (GBM).

158 egion, and rearrangements or inactivation in malignant brain tumors, suggest that LGI1 is a candidate

159 Medulloblastoma is a malignant brain tumor that arises in the cerebellum in c

160 Medulloblastoma (MB) is a malignant brain tumor that arises in the cerebellum of c

161 Medulloblastoma (MB) is a highly malignant brain tumor that occurs primarily in children.

162 Gliomas are highly malignant brain tumors that are highly invasive and resi

163 Glioblastomas are malignant brain tumors that are very difficult to cure,

164 Medulloblastomas are malignant brain tumors that arise by transformation of n

165 Medulloblastomas are malignant brain tumors that arise in the cerebellum in c

166 Medulloblastomas are malignant brain tumors that arise in the cerebellum in c

167 ermal tumors (PNETs) are a family of primary malignant brain tumors that include medulloblastomas.

168 A relatively novel combination treatment for malignant brain tumors that includes focused ultrasound

169 Glioblastomas are highly vascular malignant brain tumors that often overexpress vascular e

170 ight of clinical trials of oncolytic HSV for malignant brain tumors, these findings suggest that anti

171 Given the propensity for malignant brain tumors to infiltrate the surrounding nor

172 owever, the immune escape mechanisms used by malignant brain tumors to subvert this innate type of im

173 microenvironment might affect the ability of malignant brain tumors to traverse between brain and vas

174 lationships in newly diagnosed patients with malignant brain tumors treated with direct injections of

175 al antibody (MAb) in patients with recurrent malignant brain tumors, treated by direct injections of

176 New approaches to treating patients with malignant brain tumors use advanced magnetic resonance a

177 an effective agent used in the treatment of malignant brain tumors, was examined in an animal tumor

178 CXCL12 is a stroma-derived growth factor for malignant brain tumors, we tested the hypothesis that CX

179 (median age, 30 months) with newly diagnosed malignant brain tumors were enrolled onto this trial.

180 98 children younger than 3 years of age with malignant brain tumors were treated with prolonged posto

181 n younger than 6 years of age with recurrent malignant brain tumors who had not previously been expos

182 glioma/GBM) is the most common primary adult malignant brain tumor with poor prognosis.

183 Glioblastomas (GBMs) are malignant brain tumors with a median survival of less th

184 s intracranial growth in xenograft models of malignant brain tumors with comparable efficacy to AMD 3

185 Treatment of malignant brain tumors with conventional approaches is l

186 igh-grade glioma (HGG) is a group of primary malignant brain tumors with dismal prognosis.

187 e investigated regional therapy of recurrent malignant brain tumors with transferrin-CRM107, a conjug

188 alignant gliomas are the most common primary malignant brain tumors, with an annual incidence of 5.26