ライフサイエンスコーパス: mammalian chromosome

1 mutation frequencies at a specific site in a mammalian chromosome.

2 ression levels of mini-genes integrated into mammalian chromosomes.

3 ole in chromosome-wide replication timing of mammalian chromosomes.

4 inappropriate repair at the natural ends of mammalian chromosomes.

5 s to study intrachromosomal recombination in mammalian chromosomes.

6 n can serve as a major DSB repair pathway in mammalian chromosomes.

7 (homeologous recombination) is suppressed in mammalian chromosomes.

8 , analogous to the fragile sites observed in mammalian chromosomes.

9 of telomere replication patterns of specific mammalian chromosomes.

10 iC31 integrase, can mediate integration into mammalian chromosomes.

11 large-scale variation in G + C content along mammalian chromosomes.

12 etroposons, integrate at staggered breaks in mammalian chromosomes.

13 e for RNA in the topological organization of mammalian chromosomes.

14 l, functional and evolutionary basis for the mammalian chromosome and chromosomal banding patterns.

15 ing the mechanism of DNA damage tolerance in mammalian chromosomes and their connection to pathologic

16 The temporal order of replication of mammalian chromosomes appears to be linked to their func

17 select for loxP-specific genome targeting in mammalian chromosomes are also present.

18 Several studies reveal that mammalian chromosomes are composed of topological domain

19 Centromeres of mammalian chromosomes are rich in repetitive DNAs that a

20 We show that the distribution of cohesins on mammalian chromosome arms is not driven by transcription

21 Such divergence is unprecedented in mammalian chromosome biology and has implications for mo

22 predictions of the arrangement of ancestral mammalian chromosomes, but the basis for these rearrange

23 Replicated mammalian chromosomes condense to segregate during anaph

24 during development and provide evidence that mammalian chromosomes consist of multiple independent un

25 Mammalian chromosome duplication progresses in a precise

26 ht into the effect of reduced DSB numbers on mammalian chromosome dynamics.

27 tion, revealing that compartmentalization of mammalian chromosomes emerges independently of proper in

28 We conclude that mammalian chromosome ends are highly susceptible to homo

29 Mammalian chromosome ends contain long arrays of TTAGGG

30 telomeric DNA binding protein POT1 protects mammalian chromosome ends from the ATR-dependent DNA dam

31 Telomerase adds TTAGGG repeats onto mammalian chromosome ends, replenishing the terminal seq

32 vents DNA damage signaling and DNA repair at mammalian chromosome ends.

33 s functions in vertebrates and as a tool for mammalian chromosome engineering.

34 des an improved resource for the analysis of mammalian chromosome evolution, the identification of ca

35 nd should contribute to our understanding of mammalian chromosome evolution.

36 ther species provides an emerging picture of mammalian chromosome evolution.

37 demonstrated that in their compacted state, mammalian chromosomes form arrays of closely stacked con

38 een developed to address questions regarding mammalian chromosome function and for biotechnological a

39 to further define the elements necessary for mammalian chromosome function.

40 erstanding of the structure and evolution of mammalian chromosomes, including gene deserts, segmental

41 model in which homeologous recombination in mammalian chromosomes is suppressed by a nondestructive

42 nter-strand DNA cross-links are removed from mammalian chromosomes is unknown, these lesions are repa

43 eractions leading to kinetochore assembly on mammalian chromosomes is unknown.

44 ivalent to homogeneously staining regions in mammalian chromosomes) or extrachromosomal palindromic m

45 erated will be a cornerstone for elucidating mammalian chromosome phylogeny and the identification of

46 hromosome conformation capture revealed that mammalian chromosomes possess a rich hierarchy of struct

47 portant traits, the phylogenomic analysis of mammalian chromosomes, proofing of the BAC fingerprint m

48 e molecular mechanisms underlying folding of mammalian chromosomes remain poorly understood.

49 which may be critical for a fully functional mammalian chromosome, remains poor.

50 Establishing how mammalian chromosome replication is regulated and how gr

51 Mammalian chromosome replication starts from distinct si

52 at-rich pericentromeric regions of plant and mammalian chromosomes results from their high level of D

53 Replication time bands in mammalian chromosomes show overall congruency with struc

54 channel gene or gene cluster on a different mammalian chromosome, supporting the hypothesis that fou

55 Mammalian chromosomes terminate in stretches of repetiti

56 Mammalian chromosomes terminate with a 3' tail which con

57 breakpoint reuse are distinctive features of mammalian chromosomes that are not well understood in ev

58 leading to initiation of DNA replication in mammalian chromosomes, the time when hamster origin reco

59 rying defined site-specific DNA lesions into mammalian chromosomes, using phage integrase-mediated in

60 repair of DNA double-strand breaks (DSBs) in mammalian chromosomes, we designed DNA substrates contai

61 uble-strand break (DSB)-induced mutations in mammalian chromosomes, we stably transfected thymidine k

62 uble-strand break (DSB)-induced mutations in mammalian chromosomes, we transfected thymidine kinase (

63 Using an optical tweezers system, isolated mammalian chromosomes were held in a 1064 nm laser trap.

64 riants form a unique epigenetic landscape on mammalian chromosomes where the principal epigenetic het

65 systems and between bacterial nucleoids and mammalian chromosomes with respect to physical propertie