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1 e approximately 30% larger than those of the mammalian homolog.
2 on, and that sd activity is conserved in its mammalian homolog.
3 ganogenesis, similar to the functions of its mammalian homologs.
4 control genes identified in C. elegans have mammalian homologs.
5 h amino acid identity and structure with the mammalian homologs.
6 e of SNARE interaction within both yeast and mammalian homologs.
7 ly 140-fold), as well as in combination with mammalian homologs.
8 may act less specifically than their fly and mammalian homologs.
9 re conserved, particularly between yeast and mammalian homologs.
10 shown to be highly conserved with chick and mammalian homologs.
11 ficient frameshifting are identical to their mammalian homologs.
12 ntical, respectively, to their corresponding mammalian homologs.
13 l regulation comes from studies of yeast and mammalian homologs.
17 he Manduca genes are highly similar to their mammalian homologs and show similar biochemical properti
20 yeast SWI/SNF complex and its Drosophila and mammalian homologs are thought to control gene expressio
22 ring Drosophila development, and some of its mammalian homologs are tumor suppressors, highlighting i
23 parisons of arginine vasotocin (AVT) and its mammalian homolog arginine vasopressin (AVP) demonstrate
28 ssues, comparable to the expression of other mammalian homologs, but less restricted than the express
29 posing interactions between their respective mammalian homologs CAAT Displacement Protein (CDP; now C
30 t dELL is a nuclear protein, which, like its mammalian homologs, can increase the catalytic rate of t
32 y conserved regions of Hap5p, Php5p, and the mammalian homolog CBF-C revealed two essential domains w
33 Rad9) is required for activation of scRad53 (mammalian homolog Chk2) and transduction of the signal f
35 chicken brain is very similar to that of the mammalian homologs, consistent with the view that the ex
36 ions for understanding how disruption of its mammalian homolog contributes to cancer and metastasis.
37 elial apical membrane protein Crumbs and its mammalian homolog CRB1 in photoreceptor cell morphogenes
38 their molecular functions, including how the mammalian homologs Cripto-1 and Cryptic recognize and re
39 ns genes ced-2, ced-5, and ced-10, and their mammalian homologs crkII, dock180, and rac1, mediate cyt
41 cal substrates, the Drosophila NinaA and its mammalian homolog, cyclophilin-B, impair opsin biogenesi
42 show that both the yeast PNG1 enzyme and its mammalian homolog display N-glycanase activity towards i
44 approximately 10 years ago that Dot1 and its mammalian homolog, DOT1L (DOT1-Like), possess histone me
46 calponin homology domain (CH) protein, whose mammalian homolog Ehbp1 was previously shown to function
48 orced expression of fly eya or of one of its mammalian homologs, Eya2, triggers rapid apoptosis in in
53 sms and stability by supplying better stable mammalian homologs for structural biology and other biop
54 inase (DRK) and daughter of sevenless (DOS) (mammalian homologs, Grb2 and Gab2, respectively) and the
56 up genes have been cloned in Drosophila, and mammalian homologs have been identified for most of thes
63 ranching, whereas overexpression of Cut or a mammalian homolog in lower-level neurons resulted in tra
64 Conversely, misexpression of Dar1 or its mammalian homolog in unipolar and bipolar neurons causes
67 is regulated by a series of genes that have mammalian homologs, including rad1, rad9, hus1, and rad1
68 eported on the recombinase activities of the mammalian homologs, including the human protein, denoted
72 he Caenorhabditis elegans unc-6 locus, whose mammalian homolog is Netrin, is perhaps the best known o
75 ctively) and the GEF son of sevenless (SOS) (mammalian homolog, mSOS) are required for efficient acti
77 e in Drosophila melanogaster that have known mammalian homologs, Numb is the best candidate to have a
79 ce that the GMEBs contact Ubc9, which is the mammalian homolog of a yeast E2 ubiquitin-conjugating en
80 brid screen, SCNM1 interacted with LUC7L2, a mammalian homolog of a yeast protein involved in recogni
83 series for WD40 repeat protein 1 (Wdr1), the mammalian homolog of Aip1, and report that reductions in
84 r adhesion molecule beta-catenin, which is a mammalian homolog of ARMADILLO, a component of the WINGL
87 Recent work demonstrating a function for the mammalian homolog of BRK1 (HSPC300) in activation of Arp
88 roper subcellular localization of mPar3, the mammalian homolog of C. elegans polarity protein Par3.
94 mutation of the transcription factor Gli2, a mammalian homolog of Ci, results in severe skeletal abno
96 We studied the signaling controlled by the mammalian homolog of DAF-16, FOXO3a, in model systems of
97 (GTP)-binding protein Rho and its effector, mammalian homolog of Diaphanous (mDia), in migrating cel
100 nduced stress fiber formation caused by RhoB/mammalian homolog of Drosophila diaphanous-induced actin
101 mmalian sterile 20-like kinase 1 (Mst1) is a mammalian homolog of Drosophila Hippo, the master regula
102 The present study found that CIAP1, a major mammalian homolog of Drosophila IAPs, is irreversibly in
105 ciation inhibitor (GDI) proteins like LGN, a mammalian homolog of Drosophila Partner of Inscuteable (
107 oR protein levels are regulated by mSiah2, a mammalian homolog of Drosophila Seven in absentia that t
108 and found to be identical to RBPJkappa, the mammalian homolog of Drosophila Suppressor of Hairless (
110 trated that one of the CIF components is the mammalian homolog of Drosophila TAF(II)150, which is not
116 ter paralog of ESC, ESC-like (ESCL), and the mammalian homolog of ESC, EED, also interact with histon
118 Furthermore, the localization of MAP1B, the mammalian homolog of Futsch, is altered in ALS spinal co
119 otein of the peroxisomal membrane 22PMP, the mammalian homolog of geranylgeranyl pyrophosphate syntha
122 nterestingly, reduction of expression of the mammalian homolog of HNT, RREB1, by siRNA inhibited coll
123 kinase 1 and 2 (ERK1/2), as well as p38, the mammalian homolog of HOG1 in yeast which is a major kina
130 e extended some of these observations to the mammalian homolog of Msn, Nck-interacting kinase (NIK),
138 We speculate that Naip5 is a functional mammalian homolog of plant "resistance" proteins that mo
146 ave isolated a human cDNA clone encoding the mammalian homolog of stanniocalcin (STC), a calcium- and
148 its ability to activate CBF1/RBP-Jkappa, the mammalian homolog of Suppressor of Hairless, a protein t
149 shown to bind to HSP60, the highly conserved mammalian homolog of the bacterial protein, and it was f
152 sphorylation-dependent interaction between a mammalian homolog of the C. elegans polarity protein Par
153 n by differential display PCR of Munc13-3, a mammalian homolog of the Caenorhabditis elegans "uncoord
155 taining protein hDlg/SAP97 (DLG), which is a mammalian homolog of the Drosophila discs large tumor su
157 to 200-amino-acid N-terminal fragment of the mammalian homolog of the Drosophila Enhancer of zeste [E
158 ion factor genes whose archetype is TFCP2, a mammalian homolog of the Drosophila gene grainyhead.
160 these modifications, we examined ASH1L, the mammalian homolog of the Drosophila melanogaster Trithor
161 and characterized the mouse cDNA of a third mammalian homolog of the Drosophila period gene and desi
163 n could activate the cation channel TRPC3, a mammalian homolog of the Drosophila phototransduction ch
164 (embryonic ectoderm development) protein, a mammalian homolog of the Drosophila Polycomb group prote
166 n, Lrp4 (a co-receptor of agrin) or with the mammalian homolog of the Drosophila tumorous imaginal di
169 the first evidence for elevation of MYH, the mammalian homolog of the Escherichia coli MutY DNA glyco
170 s type 9 E4-ORF1, evolved to target the Dlg1 mammalian homolog of the membrane-associated Drosophila
171 linker histone H1oo (1) constitutes a novel mammalian homolog of the oocyte-specific linker histone
174 P)-target 1 (RAFT1, also known as FRAP) is a mammalian homolog of the Saccharomyces cerevisiae target
176 show that c-Abl binds constitutively to the mammalian homolog of the Schizosaccharomyces pombe Rad9
178 with hsp90 and a 50-kDa protein that is the mammalian homolog of the yeast cell cycle control protei
179 ere maintenance component 1, a member of the mammalian homolog of the yeast heterotrimeric CST telome
181 mber of these complexes as class II mMOB1, a mammalian homolog of the yeast protein MOB1, and show th
182 be involved in vesicle trafficking, and the mammalian homolog of the yeast septin protein cdc10, whi
187 We have examined the developmental role of a mammalian homolog of trx and putative oncogene, Mll.
188 ole in yeast, TIP does not interact with the mammalian homolog of type 2A-associated protein of 42 kD
189 protein Mig-2 (mitogen inducible gene-2), a mammalian homolog of UNC-112, and the actin binding prot
192 cently, Golgi phosphoprotein 3 (GOLPH3), the mammalian homolog of Vps74, has been shown to control th
196 part of the 19S cap, we identified USP14, a mammalian homolog of yeast Ubp6p, as being bound to the
200 DNA replication and repair in yeast, and the mammalian homolog of yFEN-1 (DNase IV, FEN-1, or MF1) pa
201 for an activator protein predicted to be the mammalian homolog of yHac1, the activity of which can be
207 phenotypes, propose the hypothesis that the mammalian homologs of Cx36.7 and Nkx2.5 lie in a pathway
209 especially dependent upon the expression of mammalian homologs of Drosophila segmentation genes.
210 catenin degradation was discovered involving mammalian homologs of Drosophila Sina (Siah), which bind
212 The Mst1 and Mst2 protein kinases are the mammalian homologs of hippo, a major inhibitor of cell p
218 Clock together with the recent discovery of mammalian homologs of per indicate that there is high st
220 To examine the functional similarity of mammalian homologs of SID-1 (SIDT1 and SIDT2), we expres
221 RB-like, E2F, and MuvB (DREAM) that contains mammalian homologs of synMuvB proteins LIN-9, LIN-37, LI
222 tudies of mouse recently have implicated the mammalian homologs of the C. elegans heterochronic gene
230 oplasmic domain binds to proteins encoded by mammalian homologs of the Drosophila seven in absentia (
231 ransmembrane domain receptor family that are mammalian homologs of the Drosophila tissue polarity gen
232 ereditary colon cancer and is one of several mammalian homologs of the Escherichia coli mutL DNA mism
235 ytosine (5mC), we identified TET proteins as mammalian homologs of the trypanosome proteins JBP1 and
236 We generated mice lacking Cks2, one of two mammalian homologs of the yeast Cdk1-binding proteins, S
239 es the possibility of as yet uncharacterized mammalian homologs of these new amphibian peptides.
245 cell death and inhibits cell proliferation, mammalian homologs of Warts, termed Lats1 and Lats2, may
246 zinc finger transcription factor PAG-3, the mammalian homologs of which are coexpressed in olfactory
247 ganic solute transporter alpha-like protein, mammalian homologs of which have been implicated in memb
250 f class III histone deacetylases such as the mammalian homologs of yeast Silent Information Regulator
253 the ATPase site motifs is a feature of many mammalian homologs, our proposed model has broad implica
254 Contrary to the observations made for its mammalian homologs, overexpression of dTIS11 does not pr
256 quired to complete mitosis, and Ess1 and its mammalian homolog, Pin1, interact directly with RNA poly
257 family of proteins (RBF1 and RBF2) and their mammalian homologs (pRB, p130, and p107) are best known
258 2 is stably associated with KHT-1, while its mammalian homolog, prostatic acid phosphatase (PAP; also
261 phila p90 ribosomal S6 kinase (S6KII) or its mammalian homolog RSK has not been performed in the cont
263 g analysis carried out on homology models of mammalian homologs shows that these family members also
265 in Drosophila cells, and their corresponding mammalian homologs STIM1 and Orai1 in T cells, as essent
266 s upward of 85% amino acid identity with its mammalian homologs (termed Siahs), but the function of t
269 ein, band 3, that are not conserved in other mammalian homologs, the question arose whether GEs can o
270 ith the recent biochemical analysis of their mammalian homologs, these results simultaneously identif
271 80% of these Drosophila glial genes have mammalian homologs; these are now excellent candidates f
272 st in Xenopus laevis where, similar to their mammalian homologs, they form functional heterodimers.
273 and because the majority of these genes have mammalian homologs, this approach provides an avenue for
275 s and some saturated pyrimidines is NEIL1, a mammalian homolog to Escherichia coli endonuclease VIII.
276 identified were: a Y-box protein (MSY2), the mammalian homolog to the Xenopus oocyte masking protein
278 y the patterns of conserved sequences in the mammalian homologs to the beta-globin LCR, we determined
279 he S. pombe telomeric protein Tpz1, like its mammalian homolog TPP1, increases the affinity of Pot1 f
280 Atg1 serine/threonine protein kinase and its mammalian homologs ULK1 and ULK2 play critical roles dur
283 as been cloned, but this N-glycanase and its mammalian homolog were reported to be incapable of degly
285 The two tomato MMPs were found to resemble mammalian homologs with respect to gelatinolytic activit
287 The Drosophila Yorkie (Yki) protein and its mammalian homolog Yes-associated protein (YAP) are poten
288 s, investigations of the role of Yki and its mammalian homolog Yes-associated protein (YAP) in develo
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