ライフサイエンスコーパス: mammary

1 ds to the formation of aggressive metastatic mammary adenocarcinoma at 9-16 months of age.

2 of cancer-induced BTP using female rats with mammary adenocarcinoma cells sealed within the tibia.

3 nsforming growth factor beta1 (TGF-beta1) in mammary adipose tissue in obese mice activates SMAD3 sig

4 reasing microRNA 140 (miR-140) expression in mammary adipose tissue through a novel negative-feedback

5 transcription factor, a master regulator of mammary alveologenesis and luminal cell differentiation,

6 question in the casein locus containing five mammary and two non-mammary genes under the control of a

7 d that patients receiving bilateral internal mammary artery (BIMA) conduits during coronary artery by

8 vival than those receiving a single internal mammary artery (SIMA), data on risk of repeat revascular

9 duit selection, including bilateral internal mammary artery and radial artery use; intraoperative gra

10 nary artery bypass grafting with an internal mammary artery and with 1 to 4 vein grafts were recruite

11 Permanent right internal mammary artery device closure seems to augment extracard

12 mination 6 weeks after distal right internal mammary artery device closure.

13 We describe a pedicled internal mammary artery osteomyocutaneous chimeric flap (PIMOC) f

14 miR-31 is highly expressed in MaSC-enriched mammary basal cell population and in mammary tumors, and

15 . (2017) establish a model for post-pubertal mammary branching morphogenesis in which position-depend

16 ede mammary gland induction, but compromises mammary bud growth, as well as TEB formation, ductal out

17 ify a hitherto unknown function for Fgf20 in mammary budding and branching morphogenesis.

18 elays formation of Eda-induced supernumerary mammary buds and normalizes the embryonic and postnatal

19 Mouse mammary buds dissected at E14 and cultured for 5 days sh

20 iol (E2) resulted in monotonic inhibition of mammary buds ductal growth.

21 ix, MSC cultured with conditioned media from mammary cancer cells expressed increased levels of alpha

22 that TAp63 is crucial for the transition of mammary cancer cells to TICs.

23 DF11 in vitro and suppresses triple-negative mammary cancer metastasis to the lung of syngeneic hosts

24 ll breast cancers and is the most aggressive mammary cancer subtype.

25 ession could be induced in murine chest wall mammary cancers with a topical toll-like receptor (TLR)-

26 yrosine kinase ERB2 (HER2), that define most mammary cancers, there are no targeted therapies for pat

27 polymorphisms as quantitative trait loci in mammary carcinogenesis, and they implicate distinct inte

28 olescence is a highly susceptible period for mammary carcinogenesis, but few prospective studies have

29 tary susceptibility for specific patterns of mammary carcinogenesis.

30 metastatic melanoma, prostate carcinoma, or mammary carcinoma cell lines.

31 ouse tumour models such as HA-expressing 4T1 mammary carcinoma cells, OVA-expressing EG7 lymphoma cel

32 -control studies carried out in Germany: the Mammary Carcinoma Risk Factor Investigation (MARIE), a b

33 take of 2-(18)F-FEtOH in 4T1 and 67NR murine mammary carcinoma tumors grown in mice was measured usin

34 mors using an in vivo mouse model of the 4T1 mammary carcinoma.

35 venting metastasis in poorly immunogenic 4T1 mammary carcinoma.

36 bal gene expression profiling of Ccn6(fl/fl) mammary carcinomas and comparison of orthologous genes w

37 ;MMTV-Cre mice developed invasive high grade mammary carcinomas with bona fide EMT, histologically si

38 Upon aging, the development of Wnt activated mammary carcinomas with squamous differentiation was acc

39 n validated against in-vivo data from murine mammary carcinomas, with particular focus placed on iden

40 changes were not the same in the HER2-driven mammary carcinomas.

41 he lactation stage, suggesting inhibition of mammary cell differentiation.

42 pport a function for BRD4 in promoting basal mammary cell epithelial differentiation, at least in par

43 tional BRCA2 loss in a non-transformed human mammary cell line and see increased replication stress d

44 r by scavenging ROS or by halting the cyclic mammary cell population expansion, attenuated tumor recu

45 In contrast, the cytokeratin 8-positive mammary cell population with progenitor properties is el

46 ons during hormonal-induced expansion of the mammary cell population.

47 ow that, unexpectedly, Par3 is essential for mammary cell survival.

48 In our in vitro model, we dosed MCF10A mammary cells at different times after serum shock to st

49 mmary microenvironment (niche) to direct non-mammary cells including testicular and embryonic stem ce

50 Human mammary cells treated with TGFbeta or undergoing EMT upr

51 raction of transplanted normal MECs with non-mammary cells within the mammary fat-pads of recipient m

52 Moreover, the mammary clock is controlled by the periductal extracellu

53 erexpression partially rescues miR31-induced mammary defects.

54 of the CDK4/6 kinases is a hallmark of most mammary-derived carcinomas.

55 Mammary-derived serotonin makes a significant contributi

56 The contribution of mammary-derived serotonin to circulating serum serotonin

57 ear whether its overexpression alters normal mammary development in vivo.

58 To study the in vivo effects of AZD4547 on mammary development, mammary epithelial cell (MEC) popul

59 During mammary development, Ptprb expression is downregulated d

60 our findings have general importance outside mammary developmental biology.

61 It represses the mammary differentiation gene GATA3 involving DNMT3b and

62 or (Fgf) receptors have a recognized role in mammary ductal development and stem cell maintenance, bu

63 ast-specific PTEN deletion greatly restricts mammary ductal elongation and induces aberrant alveolar

64 100a4-Cre) deletion of Sharpin, have reduced mammary ductal outgrowth during puberty.

65 Accordingly, stroma adjacent to invading mammary ducts of Sharpin(cpdm) mice displayed reduced co

66 f the border CTCF site separating the Csn1s1 mammary enhancer from neighboring genes resulted in the

67 is the predominant SENP transcript in human mammary epithelia but is significantly reduced in precan

68 ks, compromises the self-renewal capacity of mammary epithelia.

69 total cell lysate obtained from normal human mammary epithelial (HME-1) cells treated with variable d

70 suppressor of cell motility and invasion in mammary epithelial and breast cancer cells.

71 CaCo-2 colon, as well as normal human MCF10A mammary epithelial and human peripheral blood mononuclea

72 r and embryonic stem cells (ESCs) to adopt a mammary epithelial cell (MEC) fate.

73 o effects of AZD4547 on mammary development, mammary epithelial cell (MEC) populations, and oncogenic

74 equired for ErbB4 ICD-mediated inhibition of mammary epithelial cell differentiation in a three-dimen

75 trength between metastatic and nonmetastatic mammary epithelial cell lines, which occur over concentr

76 ediator of beta-catenin signaling and normal mammary epithelial cell physiology.

77 Here, we identify a quiescent mammary epithelial cell population expressing high level

78 In a human mammary epithelial cell system that recapitulates early

79 ANCE Here, we use an in vitro model of human mammary epithelial cell transformation to assess how mal

80 of activation in an in vitro model of human mammary epithelial cell transformation.

81 ing Lgr5-EGFP-IRES-CreERT2, to demonstrate a mammary epithelial cell-autonomous requirement of CBL an

82 lower hsa-miR-125b levels than normal human mammary epithelial cells (HMECs).

83 Viability analysis of normal mammary epithelial cells (MCF-12A) under oxygen gradient

84 Characterising the hierarchy of mammary epithelial cells (MECs) and how they are regulat

85 Mechanisms regulating the transition of mammary epithelial cells (MECs) to mammary stem cells (M

86 ctin promotes lactational differentiation of mammary epithelial cells (MECs) via its cognate receptor

87 nd receptors are recruited to the surface of mammary epithelial cells (MECs), and the vesicle transpo

88 Basal-like nonmalignant mammary epithelial cells also display an altered integri

89 yrosine kinase receptor ErbB2/HER2 in normal mammary epithelial cells and breast cancer cells.

90 m cell-like populations from non-tumorigenic mammary epithelial cells and non-aggressive breast cance

91 Here we show that normal mammary epithelial cells consume glutamine, but do not s

92 proteins that maintain the growth of starved mammary epithelial cells contingent upon epithelial cell

93 r-, progesterone receptor-, or ki67-positive mammary epithelial cells in the transgenic mice at the l

94 cell differentiation, is markedly reduced in mammary epithelial cells of transgenic mice.

95 stimulation by FGF2, and Ptprb knockdown in mammary epithelial cells resulted in a higher level of f

96 We have found that human mammary epithelial cells that undergo an epithelial-to-m

97 In contrast, Sharpin(cpdm) mammary epithelial cells transplanted in vivo into wild-

98 gnalling is decreased, matrix-attached human mammary epithelial cells upregulate and internalize beta

99 nges over time, here, we study the motion of mammary epithelial cells within engineered monolayers, i

100 PIK3R1 knockdown transforms human mammary epithelial cells, and genetic ablation of Pik3r1

101 With knockdown of SENP7S in mammary epithelial cells, Axin1-beta-catenin interaction

102 of MCF-7 breast cancer cells versus MCF-10A mammary epithelial cells, when subjected to individual a

103 and DOCK5 extends to non-transformed MCF10A mammary epithelial cells, with DOCK5 'dialing-up' and GI

104 /beta-catenin and Hgf/Met signaling in mouse mammary epithelial cells.

105 ctor-3 (GRHL3) in non-transformed basal-like mammary epithelial cells.

106 mmaH2AX foci in non-transformed MCF10A human mammary epithelial cells.

107 invasive properties to ErbB2-positive human mammary epithelial cells.

108 ical role of a novel SENP7 isoform SENP7S in mammary epithelial cells.

109 RAIL protein levels in human breast milk and mammary epithelial cells.

110 22)/503 cluster as an important regulator of mammary epithelial involution after pregnancy.

111 in breast cancer and provide a link between mammary epithelial involution, tumorigenesis, and the ph

112 reast cancer metastasis, we have generated a mammary epithelial progression series of increasingly ag

113 R-ketorolac treatment significantly reduced mammary epithelial proliferation, based on Ki67 staining

114 ce concomitantly exhibit an expansion of the mammary epithelial stem cell (MaSC) enriched basal/myoep

115 11b acts as a central intrinsic regulator of mammary epithelial stem cell quiescence and exhaustion a

116 ar-derived cells and ESCs to form functional mammary epithelial trees in vivo.

117 We generated a mouse model of mammary epithelial-specific Ccn6 deletion by developing

118 sembly of multiprotein complexes to regulate mammary epithelium and keratinocyte differentiation and

119 PRB regulates branching morphogenesis in the mammary epithelium by modulating the response of the FGF

120 Proliferative mammary epithelium from R-ketorolac-treated mice display

121 investigating trafficking events within the mammary epithelium in real time.

122 Cre-recombinase-mediated Ptch1 ablation in mammary epithelium increased proliferation and branching

123 nd genetic changes within the pre-neoplastic mammary epithelium of mice with and without stromal PTEN

124 nal deletion of both mPot1a and p53 in mouse mammary epithelium resulted in development of highly inv

125 sgenics to delete Apc and/or Apc2 from mouse mammary epithelium to elucidate the significance of thes

126 aSCs) reside in the basal compartment of the mammary epithelium, and their neoplastic counterparts, m

127 nd proper hormone receptor expression in the mammary epithelium.

128 as expected and also elicited an increase in mammary ERalpha and ERbeta expression.

129 Here, we tested whether acellular mammary extracellular matrix (mECM) preparations are suf

130 TMD cells were harvested from the mammary fat pad after transfecting MDA-MB-231 breast can

131 breast cancer cells were coinjected into the mammary fat pad of SCID mice.

132 nse drug extravasation than in contralateral mammary fat pad tissue, which is consistent with enhance

133 vivo shRNA knockdown of Ptprb in the cleared mammary fat pad transplant assay resulted in smaller epi

134 th of MDA-MB-231 TNBC cell xenografts in the mammary fat pads of female nude mice.

135 ormal MECs with non-mammary cells within the mammary fat-pads of recipient mice that had their endoge

136 of phosphatase and tensin homolog (PTEN) in mammary fibroblasts induces an oncogenic secretome that

137 mensional coculture assay for the effects of mammary fibroblasts on associated breast cancer cells.

138 in locus containing five mammary and two non-mammary genes under the control of at least seven putati

139 autophagy and cell death in both the normal mammary gland and BC cells.

140 levated serotonin concentrations in both the mammary gland and circulation compared to controls.

141 benzo-a-pyrene (BaP) metabolism in the mouse mammary gland and develop a circadian in vitro model for

142 gly, this signature is present in the normal mammary gland and is progressively lost in patients with

143 vide new insights into the role of SEMA3B in mammary gland and provides a new branch of GATA3 signali

144 rowth-hormone concentrations that may affect mammary gland and pubertal development.We evaluated the

145 t, WAP-Cre x Tph1 (FL/FL) dams had decreased mammary gland and serum serotonin concentrations compare

146 (V) chains are an abundant product of normal mammary gland basal cells, and that alpha3(V) ablation i

147 y that SHARPIN regulates the normal invasive mammary gland branching morphogenesis in an epithelial c

148 properties of stem cells that participate in mammary gland branching morphogenesis remain contested.

149 isplay convergent co-option by placental and mammary gland cell types to optimize offspring success.

150 ow-dose effects include persistent delays in mammary gland development (perfluorooctanoic acid; PFOA)

151 The p53 family member, p63, is critical for mammary gland development and contains transactivation d

152 have revealed its specific roles in pubertal mammary gland development and potential contributions to

153 Mammary gland development begins with the appearance of

154 e studies showed that it is not required for mammary gland development during puberty, it is not clea

155 not alter puberty in male and female rats or mammary gland development in female rats.

156 se environmental chemical exposure on normal mammary gland development in rats to motivate and evalua

157 Here, we examined the role of SHARPIN in mammary gland development, a process strongly regulated

158 be used to study the hormonal regulation of mammary gland development, and to test newly synthesized

159 showed that estrogens directly altered fetal mammary gland development.

160 licate FOXC1 as a new important regulator of mammary gland development.

161 emokines, is differentially expressed during mammary gland development.

162 lts provide a global, unbiased view of adult mammary gland development.

163 Serotonin is a homeostatic regulator of the mammary gland during lactation.

164 t has minimal or less effect on normal human mammary gland epithelial cells (HMECs) and estrogen rece

165 mapping of accessible chromatin in the mouse mammary gland epithelial EpH4 cell line and its Ras-tran

166 The mammary gland epithelium consists of differentiated lumi

167 dates resulted in the hyper-proliferation of mammary gland epithelium.

168 into wild-type stroma, fully repopulate the mammary gland fat pad, undergo unperturbed ductal outgro

169 essing EMT-associated genes in normal murine mammary gland homeostasis and human breast cancer still

170 To improve our knowledge of mammary gland immune protection, cows immunized either i

171 Fgf20 deficiency does not impede mammary gland induction, but compromises mammary bud gro

172 cterized by dynamic tissue remodeling in the mammary gland involving ductal elongation, resolution in

173 The female mammary gland is a very dynamic organ that undergoes con

174 her analysis of the function of TAp63 in the mammary gland is critical for improved diagnosis and pat

175 An important feature of the mammary gland is its ability to undergo profound morphol

176 In mouse models, PELP1 overexpression in the mammary gland leads to premalignant lesions and eventual

177 trolled variables across tumor and non-tumor mammary gland microvasculature with and without applicat

178 m and progenitor cell subpopulations driving mammary gland morphogenesis and homoeostasis are poorly

179 The mammary gland niche must support its associated stem cel

180 helial, stromal and systemic roles in murine mammary gland organogenesis, yet specific functions rema

181 Thus, SHARPIN is required in mammary gland stroma during development.

182 Moreover, Sharpin(cpdm) mammary gland stromal fibroblasts demonstrated defects i

183 n of neoplastic cells within the duct of the mammary gland that have not invaded into the surrounding

184 RCA-/-, p53-/- breast tumor tissue or normal mammary gland tissue with methyl-tert-butyl ether (MTBE)

185 revealed a shift from high triglycerides in mammary gland to high phospholipid levels in tumors.

186 te the interactions between CSCs and CAFs in mammary gland tumors driven by combined activation of Wn

187 e developed an ex vivo culture method of the mammary gland where the direct action of estrogens can b

188 EMT in vivo, in developing mouse embryos and mammary gland, and in vitro, in cultured 3D cell aggrega

189 ases basal levels of autophagy in the normal mammary gland, highlighting the potential of vitamin D a

190 Here, we show that, in mouse mammary gland, kidney, and human prostate, these feature

191 is during development and postnatally in the mammary gland.

192 ng E. coli vaccine-induced protection of the mammary gland.

193 hormonal action on critical targets like the mammary gland.

194 n of polar lipids is highly regulated in the mammary gland.

195 ent, and secretory function in the lactating mammary gland.

196 me and bacterial load in cows with a healthy mammary gland.

197 s necessary for long-term maintenance of the mammary gland.

198 regulating the postnatal development of the mammary gland.

199 exposure influences BaP metabolism in mouse mammary glands and describe an in vitro model that can b

200 Dams were euthanized on d10 postpartum and mammary glands and duodenal tissue were harvested.

201 report that Fgf20 is expressed in embryonic mammary glands and is regulated by the Eda pathway.

202 ecific binding of (64)Cu-DOTA-alendronate in mammary glands and mammary tumors.

203 s are enriched for cells that can regenerate mammary glands in secondary transplants.

204 ulated) were differentially expressed in the mammary glands of the two groups.

205 Mammary glands were analyzed for tumor number and immuno

206 and molecular clock gene expression in mouse mammary glands.

207 in (PTHrP) in their developing epidermis and mammary glands] with those from wild type, we show that

208 cidate the significance of these proteins in mammary homeostasis and delineate their influences on Wn

209 strains that cause persistent and transient mammary infections in dairy cattle.

210 but not in serum, suggesting that an entero-mammary link may exist for food-specific antibody-secret

211 tion factor that regulates genes involved in mammary luminal cell differentiation and tumor suppressi

212 e we report that induced p53 loss in Krt8(+) mammary luminal cells leads to their clonal expansion wi

213 addition to GATA3, FoxM1b also represses the mammary luminal differentiation marker FoxA1 by promoter

214 was to evaluate (64)Cu-DOTA-alendronate as a mammary microcalcification-targeting PET imaging agent,

215 y, we demonstrated the ability of the normal mammary microenvironment (niche) to direct non-mammary c

216 pore channel TPC2 reduced lung metastasis of mammary mouse cancer cells.

217 Brca2(-/-);p53(-/-) and Brca1(-/-);p53(-/-) mammary mouse tumours, suggesting that mitotic progressi

218 Here we compare the secretome of human mammary normal and cancer-associated fibroblasts (CAFs).

219 Mammary or subcutaneous tumours grow despite suppression

220 reERT; mT/mG), we show that Cbl/Cbl-b DKO in mammary organoids leads to hyperactivation of AKT-mTOR s

221 nd queen pheromones in social insects to the mammary pheromone produced by mother rabbits.

222 In mice, Eda regulates mammary placode formation and branching morphogenesis, b

223 d early treatment discontinuation within the Mammary Prevention.3 (MAP.3) breast cancer prevention tr

224 Mammary SCs (MaSCs) reside in the basal compartment of t

225 Either Lgr4 haploinsufficiency or mammary-specific deletion inhibited mouse mammary tumor

226 Although mammary-specific deletion of p110alpha dramatically dela

227 s to characterize dams with a lactation- and mammary-specific disruption of Lrp5 (WAP-Cre x Lrp5 (FL/

228 eeping Beauty transposon system in mice with mammary-specific inactivation of Cdh1.

229 ss these questions in the Wap locus with its mammary-specific super-enhancer separated by CTCF sites

230 nctions of specific microRNAs in controlling mammary stem cell (MaSC) activity and breast cancer form

231 These tumours exhibit a mammary stem cell (MaSC)-like expression signature and m

232 background, as well as a tamoxifen-inducible mammary stem cell (MaSC)-specific Cbl and Cbl-b double k

233 hway components, the oncogene c-Myc, and the mammary stem cell regulator Id4 This signature drove clu

234 Thus, Blimp1 expression defines a mammary stem cell subpopulation with unique functional c

235 sition of mammary epithelial cells (MECs) to mammary stem cells (MaSCs) and to tumor-initiating cells

236 show that Ptprb is highly expressed in adult mammary stem cells and also, although at lower levels, i

237 transcriptional effector, acts within mouse mammary stromal cells to direct a hormone-responsive nic

238 fat on myofibroblast differentiation in the mammary stromal microenvironment.

239 ithelium, and their neoplastic counterparts, mammary TICs (MaTICs), are thought to serve as the TICs

240 se data indicate a crucial role for TAp63 in mammary TICs and provide a mechanism for its role as a t

241 rograms promote stemness and thereby support mammary tissue outgrowth and tumors of basal origin.

242 e results in elevated expression of Ramp3 in mammary tissue through augmented promoter-enhancer inter

243 he lowest uptake in benign tumors and normal mammary tissue.

244 in situ cancers growing within primary human mammary tissues and is also required for metastasis in v

245 e results in loss of Ramp3 expression in non-mammary tissues.

246 a-catenin signaling pathways in premalignant mammary tissues.

247 ZDHHC3 ablation in human MDA-MB-231 mammary tumor cell xenografts reduced the sizes of both

248 We demonstrate here that mammary tumor cells arising from more epithelial carcino

249 1), A77636, inhibited proliferation of 4T1.2 mammary tumor cells as well as MDA-MB-231 breast cancer

250 LOXL2 ablation in mammary tumor cells dramatically decreased lung metastas

251 Data show that invading mammary tumor cells, when cultured in a stiffened three-

252 Thus, Notch-induced mammary tumor development is Rbpj-independent.

253 y) for 10 weeks during the 'risk window' for mammary tumor development.

254 ion to tamoxifen, resulting in abrogation of mammary tumor growth and progression.

255 ssess the contribution of endogenous Muc4 to mammary tumor growth properties, we first created a gene

256 enhanced, whereas overexpression, suppressed mammary tumor growth, consistent with a significant asso

257 Loss of miR-31 compromises mammary tumor growth, reduces the number of cancer stem

258 l was also estimated in-vivo in DMBA induced mammary tumor in female Sprague-Dawley rats.

259 2 transgenic mice dramatically shortened the mammary tumor latency and accelerated tumor growth due t

260 h which endogenous hyperinsulinemia promotes mammary tumor metastases.

261 hange (MNX)-we showed that mtDNA could alter mammary tumor metastasis.

262 Fibroblasts within the mammary tumor microenvironment are active participants i

263 This novel Wnt-driven mammary tumor model highlights the importance of functio

264 tracellular milieu accelerating ErbB2-driven mammary tumor progression.

265 or mammary-specific deletion inhibited mouse mammary tumor virus (MMTV)- PyMT- and MMTV- Wnt1-driven

266 c acid (PA), inhibits lung metastases in the mammary tumor virus (MMTV)-Neu transgenic mouse breast c

267 ance between mesenchymal Wingless-type Mouse Mammary Tumor Virus integration site family, member 10B

268 riven model of luminal breast cancer [murine mammary tumor virus promoter (MMTV-NIC)].

269 tered breast cancer development in the mouse mammary tumor virus-polyoma middle T-antigen model.

270 ce were generated and crossed with the Mouse Mammary Tumor Virus-Polyoma Middle T-Antigen mouse.

271 using a mouse model of bone metastasis from mammary tumor.

272 or virus (MMTV)- PyMT- and MMTV- Wnt1-driven mammary tumorigenesis and metastasis.

273 In this study, we generated a mouse model of mammary tumorigenesis harboring the MMTV-HER2 oncogene a

274 we found that ERalpha and ERbeta expression, mammary tumorigenesis, and survival are energy balance d

275 ted a significant suppression in spontaneous mammary tumorigenesis.

276 (Neu DeLetion mutant) model of ErbB2-induced mammary tumorigenesis.

277 K activation and P50 phosphorylation causing mammary tumorigenesis.

278 ed with muscle was observed in both the SSM3 mammary tumors (2.4 +/- 0.17 vs. 1.6 +/- 0.14 percentage

279 on on two separate transposon screens of 123 mammary tumors and 20 B-cell acute lymphoblastic leukemi

280 howed that HER2(+)/PIK3CA(H1047R) transgenic mammary tumors are resistant to the HER2 antibodies tras

281 for the sensitive and specific detection of mammary tumors as well as the differentiation of maligna

282 cyclin D1 expression are suppressed, primary mammary tumors from Muc4(ko)/NDL female mice exhibit sim

283 However, mammary tumors had no effect on hippocampal doublecortin

284 These mice developed multiple independent mammary tumors of which the majority resembled human ILC

285 one metastatic cancer cells, but not primary mammary tumors or visceral metastases.

286 In vivo, oncogenic PIK3CA-driven mouse mammary tumors treated daily with aspirin resulted in de

287 ng C-Met signaling were confirmed in vivo in mammary tumors using the in vivo invasion assay and intr

288 nriched mammary basal cell population and in mammary tumors, and is regulated by NF-kappaB signaling.

289 of Cdh1 does not predispose mice to develop mammary tumors, implying that mutations in additional ge

290 v mice bearing estrogen-dependent SSM3 mouse mammary tumors, male athymic nude mice bearing androgen-

291 These animals mainly developed mammary tumors, most of which had transposon insertions

292 ls (1 x 10(5) cells per injection) to induce mammary tumors.

293 64)Cu-DOTA-alendronate in mammary glands and mammary tumors.

294 leads to premalignant lesions and eventually mammary tumors.

295 , Wap-Int3/P50 knockout mice did not develop mammary tumors.

296 ells, and that alpha3(V) ablation in a mouse mammary tumour model inhibits mammary tumour progression

297 asis, an MMTV-PyMT transgenic mouse model of mammary tumour progression and clinical breast cancer sa

298 ion in a mouse mammary tumour model inhibits mammary tumour progression by reducing the proliferative

299 All induced mice develop mammary tumours with 9qA1 (Yap1) and/or 6qA2 (Met) ampli

300 cells and predisposes them to development of mammary tumours with loss of luminal identity.